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Introduction:
BioM2MetDisease is a database aims to establish the manually curated associations between various metabolic diseases and biomolecules. In the current release, BioM2MetDisease provides 2681 manually curated associations including relationships between 524 miRNAs and 45 metabolic diseases; 281 metabolites and 35 metabolic diseases; 349 small molecules (or drugs) and 57 metabolic diseases across 14 species from nearly 1300 published literatures (the same biomolecules in different species were counted only once).
Metabolic disease also known as metabolic disorder, which has become one of the leading threat to people’s health in the word. Emerging evidence suggest that metabolic disease is related with the aberrant level of multiple type biomolecules.
MicroRNA is a small non-coding RNA molecule containing about 22 nucleotides, which functions in RNA silencing and post-transcriptional regulation of gene expression. Evidence suggests that microRNAs play critical roles in a number of human diseases, including metabolic diseases.
Metabolite is the intermediates and products of metabolism, which directly reflect the physiological state of biological systems. Accumulating evidence indicate that metabolites are also closely related with metabolic diseases.
Small molecule (or drug) can regulate multiple biological processes and have been used to therapy human diseases.
Statistics:
Today is : 2024-09-19
- Number of diseases: 78
- Number of miRNAs: 524
- Number of metabolites: 281
- Number of small molecules: 153
- Number of drugs: 196
- Number of species: 14
- Number of pubmed literatures: 1261
Latest News:
- The data in BioM2MetDisease was updated with 499 new entries. (Mar 20, 2017)
- BioM2MetDisease has been formally launched and is freely available at http://www.bio-bigdata.com/BioM2MetDisease/. (Sep 18, 2016)
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