CHNmiRD is a web-based tool for inferring novel miRNA-disease associations based on a complex heterogeneous network (CHN) involving 402 miRNAs and 5080 diseases. CHNmiRD integrates multiple genomic and phenotype data, including protein-protein interaction data, gene ontology data, experimentally verified miRNA-target relationships, disease phenotype information and known miRNA-disease connections. In particular, CHNmiRD displays excellent performance for diseases without any known related miRNAs. Given a disease, CHNmiRD provides a candidate miRNA list and assigns each miRNA a probability score which reflects the correlation between the miRNA and the disease. It is noteworthy that CHNmiRD only provides novel miRNA-disease associations, the known miRNA-disease associations from HMDD (version 2.0) (Lu et al. 2008) can be down loaded from the 'DOWNLOAD' page.