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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| ACC | ENSG00000175592 | FOSL1 | Cytokine Receptors | 1.754e-03 | 2.807e-02 | -0.3508 | -0.9965 | risk | details |
| ACC | ENSG00000198205 | ZXDA | Antimicrobials | 2.045e-03 | 3.272e-02 | 0.3978 | 0.9959 | protective | details |
| ACC | ENSG00000107485 | GATA3 | Antigen Processing a... | 1.585e-03 | 2.536e-02 | -0.4802 | -0.9968 | risk | details |
| ACC | ENSG00000165891 | E2F7 | Antigen Processing a... | 2.381e-03 | 3.810e-02 | -0.4181 | -0.9952 | risk | details |
| ACC | ENSG00000179388 | EGR3 | Cytokines | 1.377e-03 | 1.384e-02 | 0.4145 | 0.9972 | risk | details |
| ACC | ENSG00000179388 | EGR3 | TGFb Family Member | 1.730e-03 | 1.384e-02 | 0.6447 | 0.9965 | risk | details |
| ACC | ENSG00000197279 | ZNF165 | Antigen Processing a... | 1.377e-03 | 2.204e-02 | 0.5577 | 0.9972 | protective | details |
| ACC | ENSG00000112182 | BACH2 | Cytokines | 1.712e-03 | 1.556e-02 | 0.3992 | 0.9966 | risk | details |
| ACC | ENSG00000112182 | BACH2 | Interleukins | 1.946e-03 | 1.556e-02 | 0.6622 | 0.9961 | risk | details |
| ACC | ENSG00000006047 | YBX2 | Cytokines | 1.555e-03 | 2.488e-02 | 0.3888 | 0.9969 | risk | details |
| ACC | ENSG00000163064 | EN1 | Cytokines | 1.524e-03 | 1.896e-02 | 0.3315 | 0.997 | risk | details |
| ACC | ENSG00000163064 | EN1 | TCR signaling Pathwa... | 2.370e-03 | 1.896e-02 | -0.4678 | -0.9953 | risk | details |
| ACC | ENSG00000106571 | GLI3 | Antigen Processing a... | 1.393e-03 | 1.114e-02 | -0.4332 | -0.9972 | risk | details |
| ACC | ENSG00000106571 | GLI3 | Natural Killer Cell ... | 1.393e-03 | 1.114e-02 | -0.4421 | -0.9972 | risk | details |
| ACC | ENSG00000112033 | PPARD | Natural Killer Cell ... | 1.613e-03 | 2.581e-02 | 0.4422 | 0.9968 | protective | details |
| ACC | ENSG00000113722 | CDX1 | Cytokines | 1.202e-03 | 1.923e-02 | 0.3895 | 0.9976 | risk | details |
| ACC | ENSG00000006468 | ETV1 | TGFb Family Member | 1.715e-03 | 1.490e-02 | 0.7332 | 0.9966 | risk | details |
| ACC | ENSG00000095794 | CREM | Antimicrobials | 1.094e-03 | 1.751e-02 | -0.3872 | -0.9978 | risk | details |
| ACC | ENSG00000171161 | ZNF672 | Cytokine Receptors | 1.767e-03 | 1.040e-02 | -0.3712 | -0.9965 | risk | details |
| ACC | ENSG00000171161 | ZNF672 | Natural Killer Cell ... | 1.866e-03 | 1.040e-02 | -0.4113 | -0.9963 | risk | details |