RNAactDrug a comprehensive database of RNAs associated with Drug sensitivity from multi-omics data

RNAactDrug is a comprehensive resource for querying associations between drug sensitivity and RNA molecules including mRNAs, lncRNAs and miRNAs at four molecular levels (expression, copy number variation, mutation and methylation) from integrated analysis of three large-scale pharmacogenomic databases (GDSC, CellMiner and CCLE). Currently, RNAactDrug contains more than 4924200 RNA molecules-drug sensitivity associations at multidimensional molecular levels covering more than 19770 mRNAs, 11119 lncRNAs, 438 miRNAs and 4155 drugs. RNAactDrug aims to help make use of the full breadth and depth of existing large-scale pharmacogenomic data by making this knowledge accessible to both basic researchers.


The drug sensitivity-RNA molecule associations in RNAactDrug
Omics drug-mRNA drug-lncRNA drug-miRNA
Associations mRNA drug Associations lncRNA drug Associations miRNA drug
expression 39835 10371 24 7502 2229 23 419 210 19
CNV 5368 3796 16 361 271 12 - - -
methylation 8204 4609 17 453 230 17 - - -
mutation 47858 15517 24 1979 712 22 - - -
The drug sensitivity-RNA molecule associations in RNAactDrug
Omics drug-mRNA drug-lncRNA drug-miRNA
Associations mRNA drug Associations lncRNA drug Associations miRNA drug
expression 1315879 16456 198 7922 113 197 - - -
CNV 1063322 17759 155 496299 8110 154 - - -
methylation 1167600 15926 197 7855 133 196 - - -
mutation 392 307 77 13 11 10 - - -
The drug sensitivity-RNA molecule associations in RNAactDrug
Omics drug-mRNA drug-lncRNA drug-miRNA
Associations mRNA drug Associations lncRNA drug Associations miRNA drug
expression 1182814 15853 3321 35793 801 2373 28536 232 1980
methylation 730575 18002 2138 19108 465 1749 - - -
mutation 84712 4245 1821 - - - - - -

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CCLE CellMiner CellMiner GDSC

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