| Details |
| Disease Name | Parkinson Disease |
| Nocoding RNA Name | dme-miR-133-3p |
| Expression Pattern | up-regulated |
| Species | Drosophila |
| Detection Methods | high-throughput sequencing,qRT-PCR etc. |
| Target | N/A |
| Tissue | brain |
| Treatment | N/A |
| PubMed ID | 26361355 |
| Year | 2015 |
| Detail Description | five mature miRNAs (dme-miR-1008-5p, dme-miR-133-3p, dme-miR-137-3p, dme-miR-13b-3p, dme-miR-932-5p) were differentially expressed between PD and control groups (p<0.05). Interestingly, all these miRNAs were upregulated in PD flies. Among them, dme-miR-133-3p, dme-miR-137-3p and dme-miR-13b-3p (the mature sequence both for dme-mir-13b-1 and dme-mir-13b-2) were highly conserved from flies to humans and enriched in nervous system. We choose them for validation using qRT-PCR. The results were consistent with miRNA sequencing data. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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