Details
Disease Name Alzheimer Disease
Nocoding RNA Name mmu-miR-1
Expression Pattern differentially expressed
Species Mus musculus
Detection Methods qRT-PCR,Luciferase Reporter Assay etc.
Target Stx6
Tissue brain
Treatment N/A
PubMed ID 24022509
Year 2013
Detail Description We found for the first time miRNAs that were inversely regulated in AD and EE, and may affect synaptic proteins and modulators, molecular factors associated with AD pathology, and survival and neuroprotective factors. MiRNAs that were upregulated only in 3xTgAD mice model of AD compared with their control mice were localized to synapses, predicted to downregulate essential synaptic proteins and are highly associated with regulating apoptosis, AD-associated processes and axon guidance.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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