| Details |
| Disease Name | Alzheimer Disease |
| Nocoding RNA Name | hsa-miR-29b-1 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Western Blot,Luciferase Reporter Assay,qRT-PCR,Northern Blot etc. |
| Target | BACE1 |
| Tissue | brain |
| Treatment | N/A |
| PubMed ID | 18434550 |
| Year | 2008 |
| Detail Description | We show here that miR-29a,miR-29b-1,and miR-9 can regulate BACE1 expression in vitro.The miR-29a,miR-29b-1 cluster was significantly(and AD-dementia-specific)decreased in AD patients displaying abnormally high BACE1 protein.Finally,we provide evidence for a potential causal relationship between miR-29a/b-1 expression and Aβ generation in a cell culture model. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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