Details
Disease Name Alzheimer Disease
Nocoding RNA Name hsa-miR-101
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods qRT-PCR etc.
Target N/A
Tissue brain
Treatment N/A
PubMed ID 18434550
Year 2008
Detail Description We show here that miR-29a,miR-29b-1,and miR-9 can regulate BACE1 expression in vitro.The miR-29a,miR-29b-1 cluster was significantly(and AD-dementia-specific)decreased in AD patients displaying abnormally high BACE1 protein.Finally,we provide evidence for a potential causal relationship between miR-29a/b-1 expression and Aβ generation in a cell culture model.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

Contact wanglh211@163.com for inquiries and feedback

© All right reserved 2016