Details
Disease Name Alzheimer Disease
Nocoding RNA Name hsa-miR-146a
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods miRNA array,Western Blot,Luciferase Reporter Assay etc.
Target CFH
Tissue brain(Human neural cells)
Treatment N/A
PubMed ID 19540598
Year 2009
Detail Description These data suggest that (1) as in AD brain,NF-jB-sensitive,miRNA-146a mediated,modulation of CFH gene expression may contribute to inflammatory responses in aluminum-stressed HN cells,and (2) underscores the potential of nanomolar aluminum to drive genotoxic mechanisms characteristic of neurodegenerative disease processes.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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