| Details |
| Disease Name | Alzheimer Disease |
| Nocoding RNA Name | hsa-miR-29b-1 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | qRT-PCR,Western Blot,Luciferase Reporter Assay etc. |
| Target | SPTLC2 |
| Tissue | brain |
| Treatment | N/A |
| PubMed ID | 21994399 |
| Year | 2011 |
| Detail Description | We identified that the loss of miR-137,-181c,-9,and 29a/b-1 increases SPT and in turn Aβlevels,and provides a mechanism for the elevated risk of AD associated with age,high-saturated-fat diet,and gender.Finally,these results suggest SPT and the respective miRNAs may be potential therapeutic targets for sporadic AD. |
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback
© All right reserved 2016