Details
Disease Name Alzheimer Disease
Nocoding RNA Name mmu-miR-16
Expression Pattern up-regulated
Species Mus musculus
Detection Methods SemiQuantitative RT-PCR,Real-time RT-PCR,Western Blot,Luciferase Reporter Assay etc.
Target APP
Tissue brain
Treatment N/A
PubMed ID 20619502
Year 2012
Detail Description Overexpression of miR-16,both in vitro and in vivo,led to reduced APP protein expression.Taken together,these findings demonstrate that APP is a target of miR-16 and the abnormally low expression of miR-16 could potentially lead to APP protein accumulation in AD mice.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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