| Details |
| Disease Name | Alzheimer Disease |
| Nocoding RNA Name | mmu-miR-222 |
| Expression Pattern | down-regulated |
| Species | Mus musculus |
| Detection Methods | RT-qPCR,Luciferase Reporter Assay,Western Blot etc. |
| Target | p27Kip1 |
| Tissue | cerebral cortex |
| Treatment | N/A |
| PubMed ID | 26398571 |
| Year | 2015 |
| Detail Description | MiR-222 was downregulated in AD, in association with p27Kip1 upregulation. MiR-222 can directly target p27Kip1 by binding to the 3'-UTR of p27Kip1 inducing the translational repression of p27Kip1. Therefore, downregulation of miR-222 may be correlated with the dysregulation of the cell cycle in AD by affecting the expression of p27Kip1. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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