Details
Disease Name Alzheimer Disease
Nocoding RNA Name mmu-miR-29c
Expression Pattern down-regulated
Species Mus musculus
Detection Methods RT-PCR,transfection,Western Blot,Luciferase Reporter Assay,Immunohistochemistry etc.
Target NAV3
Tissue hippocampus and the frontal cortex
Treatment N/A
PubMed ID 26212654
Year 2015
Detail Description We observed that miR-29c directly mediated downregulation of NAV3 protein expression in vitro.Our results showed that miR-29c was one of the multiple miRNAs that regulate expression of NAV3 and suggested that miR-29c may play a vital role in AD neurodegenerative processes by regulating NAV3 expression,as well as other miR-29c targets such as BACE1,at least in the young AD mouse.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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