Details
Disease Name Alzheimer Disease
Nocoding RNA Name 17A
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time RT-PCR,Immunoprecipitation,Western Blot etc.
Target N/A
Tissue brain
Treatment N/A
PubMed ID 20888417
Year 2011
Detail Description 17A is expressed in human brain, and we report that it is upregulated in cerebral tissues derived from Alzheimer disease patients. We demonstrate that 17A expression in neuroblastoma cells enhances the secretion of amyloidβpeptide (Aβ) and the Aβx-42/Αβx-40 peptide ratio and that its synthesis is induced in response to inflammatory stimuli.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

Contact wanglh211@163.com for inquiries and feedback

© All right reserved 2016