17A is expressed in human brain, and we report that it is upregulated in cerebral tissues derived from Alzheimer disease patients. We demonstrate that 17A expression in neuroblastoma cells enhances the secretion of amyloidβpeptide (Aβ) and the Aβx-42/Αβx-40 peptide ratio and that its synthesis is induced in response to inflammatory stimuli.
NSDNA: The Nervous System Disease NcRNAome Atlas
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