Details
Disease Name Parkinson Disease
Nocoding RNA Name hsa-miR-205
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Western Blot,Quantitative Real-time PCR,Luciferase Reporter Assay etc.
Target LRRK2
Tissue brain(frontal cortex)
Treatment N/A
PubMed ID 23125283
Year 2013
Detail Description the level of miR-205 expression was remarkably downregulated in the frontal cortex of PD patients compared with NPC,As a result, the luciferase activity of pGL3-LRRK2was significantly decreased by co-expression of miR-205, which was also dose-dependent.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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