| Details |
| Disease Name | Parkinson Disease |
| Nocoding RNA Name | hsa-miR-7 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Real-time PCR,Reporter gene assay,Western Blot,Immunocytochemistry etc. |
| Target | RelA |
| Tissue | MPP-induced toxicity in dopaminergic SH-SY5Y cell line |
| Treatment | N/A |
| PubMed ID | 25232110 |
| Year | 2014 |
| Detail Description | To investigate the role of miR-7 in the cell death pathway initiated by MPP, human dopaminergic SH-SY5Y cells were transfected with either pre-miR-7 or pre-miR-SC for 48 h. Transfected cells were treated with varying concentrations of MPP for 24 h before assessing cell survival. transfection of pre-miR-7 resulted in significantly higher cell viability following treatment with 2 and 3 mM MPP.miR-7 significantly decreased luciferase activity from the RelA 3-UTR construct. |
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback
© All right reserved 2016