These experiments identified 24 mature miRNAs that were misregulated in LRRK2 KO mice when a FDR of 0.2 was used. By qRT-PCR, we confirmed significant changes in 3 miRNAs in LRRK2-deficient mice when compared to controls, includingmiR-16 (p<0.0003, 2.1 fold), miR-15a (p=0.0128, 1.9 fold), and miR-25 (p=0.0037, 1.6 fold).
NSDNA: The Nervous System Disease NcRNAome Atlas
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