Disease Name |
Parkinson Disease |
Nocoding RNA Name |
mmu-miR-15a |
Expression Pattern |
up-regulated |
Species |
Mus musculus |
Detection Methods |
microarray,Real-time qRT-PCR etc. |
Target |
N/A |
Tissue |
brain(Striatal tissue) |
Treatment |
N/A
|
PubMed ID |
24427314 |
Year |
2014 |
Detail Description |
These experiments identified 24 mature miRNAs that were misregulated in LRRK2 KO mice when a FDR of 0.2 was used. By qRT-PCR, we confirmed significant changes in 3 miRNAs in LRRK2-deficient mice when compared to controls, includingmiR-16 (p<0.0003, 2.1 fold), miR-15a (p=0.0128, 1.9 fold), and miR-25 (p=0.0037, 1.6 fold). |
|