Details
Disease Name Parkinson Disease
Nocoding RNA Name mmu-miR-26b
Expression Pattern up-regulated
Species Mus musculus
Detection Methods microarray etc.
Target N/A
Tissue brain(Striatal tissue)
Treatment N/A
PubMed ID 24427314
Year 2014
Detail Description These experiments identified 24 mature miRNAs that were misregulated in LRRK2 KO mice when a FDR of 0.2 was used. By qRT-PCR, we confirmed significant changes in 3 miRNAs in LRRK2-deficient mice when compared to controls, includingmiR-16 (p<0.0003, 2.1 fold), miR-15a (p=0.0128, 1.9 fold), and miR-25 (p=0.0037, 1.6 fold).

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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