Details
Disease Name Parkinson Disease
Nocoding RNA Name mmu-miR-124
Expression Pattern down-regulated
Species Mus musculus
Detection Methods RT-PCR,Luciferase Reporter Assay etc.
Target Bim
Tissue brain
Treatment N/A
PubMed ID 25976060
Year 2015
Detail Description we found that the expression of miR-124 decreased after intraperitoneal injection of MPTP;The decrease of miR-124 in DA neurons was determined again on MPP+-intoxicated SH-SY5Y cells in vitro;MiR-124 attenuates mitochondria-dependent apoptotic cell death by targeting to Bim.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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