Details
Disease Name Muscular Dystrophy, Duchenne
Nocoding RNA Name nclNT44s2
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR,Northern Blot,Luciferase Reporter Assay etc.
Target Dp427m
Tissue cell lines(human RD and SJCRH30 rhabdomyosarcoma cell lines,SH-SY5Y neuroblastoma cell lines and both normal and MyoD-induced fibroblasts)
Treatment N/A
PubMed ID 23028937
Year 2012
Detail Description Overall these findings unveil an unprecedented complexity of the transcriptional pattern of the DMD locus and reveal that DMD lncRNAs may contribute to the orchestration and homeostasis of the muscle dystrophin expression pattern by either selective targeting and down-modulating the dystrophin promoter transcriptional activity.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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