Target PMID Function Species Induce.Inhibit Drug.Combination Effect Regulation Journal Cell.Type Cell.Name Detection.Method OCT4 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR OCT4 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR OCT4 29767511 Reproductive-toxicity Mus musculus Induce - - Downregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR OCT4 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR OCT4 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Large cell lung cancer cell NCI-H460 QRT-PCR, Western blot OCT4 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot OCT4 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Front Oncol Head and neck squamous cell carcinoma cell SAS HN-CICs Western blot OCT4 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Front Oncol Head and neck squamous cell carcinoma cell SAS-CisPt R Western blot 70S6K 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Phosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot 8-nitroguanine 20804627 Neuronal-toxicity Mus musculus Induce Taurine detoxicity Upregulation J Biomed Sci - - IHC 8-OHdG 28849511 Kidney-toxicity Mus musculus Induce Taurine detoxicity Upregulation Adv Exp Med Biol - - IHC ABCA1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ABCA3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ABCA9 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ABCB1 29274627 Lung-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 ELISA ABCB1 19513507 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Hepatocellular carcinoma cell HEPG2 RT-PCR, Western blot ABCB1 19513507 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 RT-PCR, Western blot ABCC 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ABCC1 29274627 Lung-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 ELISA ABCC1 19513507 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Hepatocellular carcinoma cell HEPG2 RT-PCR, Western blot ABCC1 19513507 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 RT-PCR, Western blot ABCC13 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ABCC2 19513507 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Hepatocellular carcinoma cell HEPG2 RT-PCR, Western blot ABCC2 19513507 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 RT-PCR, Western blot ABCC5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ABCG2 29274627 Lung-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 ELISA, QRT-PCR ABHD1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ABL1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ABL1 21570118 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelocytic leukemia cell CML-LBC QRT-PCR ABL1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell HL-60 QRT-PCR ABL1 24939418 Leukemia Homo sapiens Inhibit Bortezomib synergy Downregulation Mol Med Rep Chronic myelogenous leukemia cell K-562 QRT-PCR,Western blot ABL1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot ABL1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 QRT-PCR, Western blot ABL1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot ABL1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Burkitt's lymphoma cell Raji QRT-PCR, Western blot ABL1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Myeloma cell RPMI 8226 QRT-PCR, Western blot ABL1 22898604 Leukemia Homo sapiens Inhibit - - Downregulation Blood Chronic myelogenous leukemia cell K-562 Western blot ABL1 22339968 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5 Western blot ABL1 22339968 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5R Western blot ABL1 17550858 Leukemia Homo sapiens Inhibit Dl-buthionine-(s,r)-sulfoximine synergy Dephosphorylation,Upregulation Haematologica Chronic myeloid leukemia cell KCL22-r Western blot ABL1 27965050 Leukemia Homo sapiens Inhibit - - Downregulation J Ethnopharmacol Chronic myelogenous leukemia cell K-562 Western blot ABL1 17121903 Leukemia Homo sapiens Inhibit - - Downregulation Clin Cancer Res Embryonic kidney cell HEK-293 Western blot ABL1 11721366 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot ABL1 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot ABL1 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot ABL1 24129092 Leukemia Homo sapiens Inhibit - - Downregulation Hematology Chronic myelogenous leukemia cell K-562 Western blot ABL1 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Phosphorylation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 Western blot ABLIM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ACC 25344585 Leukemia Homo sapiens Inhibit - - Dephosphorylation Mol Cancer Ther Histiocytic lymphoma cell U-937 Western blot ACH3 25628765 Leukemia Homo sapiens Inhibit Panobinostat synergy Downregulation Clin Epigenetics Leukemia cell A/E9A;NRAS G12D Western blot ACO1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Acta2 25123535 Pulmonary-fibrosis Rattus norvegicus Inhibit - - Downregulation Life Sci - - IHC Acta2 31612257 Renal-fibrosis Rattus norvegicus Inhibit - - Downregulation Naunyn Schmiedebergs Arch Pharmacol - - QRT-PCR Acta2 27671604 Heart-toxicity Rattus norvegicus Induce - - Upregulation Sci Rep - - QRT-PCR,Western blot, IFA Acta2 31270803 Liver-toxicity Rattus norvegicus Induce - - Upregulation J Cell Physiol - - Western blot ACTA2 30317545 Skin-toxicity Homo sapiens Induce - - Downregulation J Cell Physiol Primary skin fibroblast Primary skin fibroblast IFA, QRT-PCR, Western blot ACTA2 32954055 Vascular-toxicity Homo sapiens Induce - - Upregulation Bioact Mater Primary coronary artery smooth muscle cell PCASMCs QRT-PCR ACTA2 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR,Western blot, IFA ACTA2 32954055 Vascular-toxicity Homo sapiens Induce - - Upregulation Bioact Mater Aortic SMC cell VSMCs Western blot ACTA2 30677399 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Chem Biol Interact Hepatic stellate cell LX-2 Western blot ACTB 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ACTG1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ACTIN 20164031 Leukemia Homo sapiens Inhibit - - Downregulation Folia Histochem Cytobiol Chronic myelogenous leukemia cell K-562 Flow cytometry ACTL6B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ACTN3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ADAM28 26340916 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res B cell acute lymphoblastic leukemia cell B-ALL QRT-PCR,Western blot ADAM29 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ADAMDEC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ADAMTS2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ADAMTS5 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ADAR 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ADAR 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR ADAR 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 QRT-PCR ADAR 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B QRT-PCR ADENINE 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation Cancers (Basel) Cervical carcinoma cell Ca Ski Western blot ADENINE 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation Cancers (Basel) Cervix squamous cell carcinoma cell SiHa Western blot ADFP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ADH1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AFF4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Afp 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR AFP 23382965 Gastric-cancer Homo sapiens Inhibit - - Downregulation PLoS One Gastric cancer cell FU97 QRT-PCR, Western blot AFTPH 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Agt12 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR Agt13 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR Agt3 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR Agt5 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR AHR 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - Kit AHSA2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AHSG 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis AID 21570118 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelocytic leukemia cell CML-LBC QRT-PCR, Western blot Aif 19141569 Liver-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Ind Health Hepatocyte Hepatocytes Western blot AIF 18695917 Cervical-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Cervical adenocarcinoma cell HeLa Western blot AIF 19771260 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot AIF 15604259 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Cervical adenocarcinoma cell HeLa Western blot AIF 15604259 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Cervical adenocarcinoma cell HeLa Western blot AKAP13 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Akap3 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR, Western blot AKAP3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Akap4 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR, Western blot AKAP8L 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AKAP9 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AKNA 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis akt1 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Environ Pollut - - Western blot Akt1 31326754 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - QRT-PCR Akt1 32184170 Muscle-toxicity Mus musculus Induce - - Dephosphorylation Toxicol In Vitro Myoblast cell C2C12 Western blot Akt1 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Downregulation Int J Biochem Cell Biol - - Western blot Akt1 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Downregulation Int J Biochem Cell Biol Myoblast cell C2C12 Western blot Akt1 28454374 Skin-cancer Mus musculus Inhibit - - Dephosphorylation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell Western blot Akt1 28454374 Skin-cancer Mus musculus Inhibit - - Dephosphorylation Oncol Lett Melanoma cell B16 Western blot Akt1 22622864 Muscle-toxicity Mus musculus Induce - - Dephosphorylation Arch Toxicol Myoblast cell C2C12 Western blot Akt1 21180886 Leukemia Rattus norvegicus Inhibit Ly294002 synergy Phosphorylation Braz J Med Biol Res Basophilic leukemia cell RBL-2H3 Western blot Akt1 20299303 Skin-toxicity Mus musculus Induce - - Phosphorylation,Downregulation Environ Health Perspect Myoblast cell C2C12 Western blot Akt1 20299303 Skin-toxicity Mus musculus Induce - - Phosphorylation,Downregulation Environ Health Perspect - - Western blot Akt1 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Dephosphorylation Biomed Pharmacother Heart myoblast H9C2 Western blot Akt1 27980225 Liver-toxicity Rattus norvegicus Induce Melatonin detoxicity Dephosphorylation Oncotarget - - Western blot Akt1 27664319 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation Regul Toxicol Pharmacol Brain microglia cell HAPI Western blot Akt1 15688020 Leukemia Cercopithecus aethiops Inhibit - - Upregulation Oncogene Kidney cell COS-1 Western blot Akt1 12168106 Leukemia Homo sapiens Inhibit - - Downregulation Int J Oncol Histiocytic lymphoma cell U-937 Western blot Akt1 26359868 Muscle-toxicity Mus musculus Induce - - Dephosphorylation PLoS One Myoblast cell C2C12 Western blot Akt1 23662152 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Dephosphorylation Evid Based Complement Alternat Med - - Western blot AKT1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AKT1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR AKT1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR AKT1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR AKT1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR AKT1 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR AKT1 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR AKT1 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR AKT1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR AKT1 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Phosphorylation,Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot AKT1 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot AKT1 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot AKT1 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot AKT1 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot AKT1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Dephosphorylation Endocr Relat Cancer Ovarian cancer cell SK-OV-3 Western blot AKT1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Dephosphorylation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot AKT1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Dephosphorylation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 Western blot AKT1 23255002 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation Int J Oncol Breast cancer cell MCF7 Western blot AKT1 23239002 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Dephosphorylation Chin J Integr Med Acute promyelocytic leukemia cell HL-60 Western blot AKT1 23178716 Ovary-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation FEBS Lett Ovarian carcinoma cell HEY Western blot AKT1 22730174 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation J Cell Biochem Hepatocellular carcinoma cell HEPG2 Western blot AKT1 22730174 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation J Cell Biochem Hepatocellular carcinoma cell SMMC-7721 Western blot AKT1 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Dephosphorylation PLoS One Prostate carcinoma cell LNCaP Western blot AKT1 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Dephosphorylation PLoS One Prostate carcinoma cell PC-3 Western blot AKT1 22339968 Leukemia Homo sapiens Inhibit - - Dephosphorylation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5 Western blot AKT1 22339968 Leukemia Homo sapiens Inhibit - - Dephosphorylation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5R Western blot AKT1 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Downregulation Int J Oncol Liver cancer cell BEL-7402 Western blot AKT1 21655183 Ovary-cancer Homo sapiens Inhibit Ly294002 synergy Dephosphorylation PLoS One Ovarian cancer cell COC1 Western blot AKT1 21655183 Ovary-cancer Homo sapiens Inhibit Ly294002 synergy Dephosphorylation PLoS One Ovarian cancer cell A2780 Western blot AKT1 21655183 Ovary-cancer Homo sapiens Inhibit Ly294002 synergy Dephosphorylation PLoS One Ovarian cancer cell OVCAR-3 Western blot AKT1 21649584 Liver-cancer Homo sapiens Inhibit - - Phosphorylation Biochem J Hepatocellular carcinoma cell HEPG2 Western blot AKT1 21649584 Liver-cancer Homo sapiens Inhibit - - Phosphorylation Biochem J Liver cancer cell Huh7 Western blot AKT1 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Toxicol Sci Epidermoid carcinoma cell A-431 Western blot AKT1 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Toxicol Sci Keratinocyte HACAT Western blot AKT1 21180886 Leukemia Homo sapiens Inhibit Ly294002 synergy Phosphorylation Braz J Med Biol Res Acute promyelocytic leukemia cell HL-60 Western blot AKT1 20862710 Breast-cancer Homo sapiens Inhibit - - Phosphorylation J Cell Biochem Breast epithelial cell MCF 10A Western blot AKT1 20592496 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Biol Ther Osteosarcoma cell HOS Western blot AKT1 20534739 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res B cell chronic lymphocytic leukemia cell B-CLL Western blot AKT1 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Phosphorylation,Downregulation Autophagy Fibrosarcoma cell HT1080 Western blot AKT1 20137118 Leukemia Homo sapiens Inhibit Ly294002 synergy Upregulation,Phosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot AKT1 20137118 Leukemia Homo sapiens Inhibit Rapamycin synergy Upregulation,Phosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot AKT1 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Upregulation,Phosphorylation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot AKT1 19457607 Leukemia Homo sapiens Inhibit - - Dephosphorylation Cancer Lett Acute promyelocytic leukemia cell NB4 Western blot AKT1 19457607 Gastric-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Lett Gastric cancer cell MGC-803 Western blot AKT1 19457607 Gastric-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Lett Gastric adenocarcinoma cell SGC-7901 Western blot AKT1 19242099 Brain-cancer Homo sapiens Inhibit Irradiation synergy Dephosphorylation Autophagy Glioblastoma cell U-118MG Western blot AKT1 18937079 Liver-cancer Homo sapiens Inhibit Wortmannin synergy Dephosphorylation Med Oncol Hepatocellular carcinoma cell HEPG2 Western blot AKT1 18566239 Leukemia Homo sapiens Inhibit - - Downregulation Mol Cancer Ther Acute promyelocytic leukemia cell NB4 Western blot AKT1 18566239 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Acute promyelocytic leukemia cell NB4 Western blot AKT1 18566239 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Cancer Ther Breast adenocarcinoma cell MDA-MB-468 Western blot AKT1 18546268 Leukemia Homo sapiens Inhibit Genistein synergy Dephosphorylation Int J Cancer Histiocytic lymphoma cell U-937 Western blot AKT1 18491231 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Dephosphorylation Apoptosis Acute promyelocytic leukemia cell NB4 Western blot AKT1 18359480 Leukemia Homo sapiens Inhibit Quercetin synergy Phosphorylation Biochem Pharmacol Histiocytic lymphoma cell U-937 Western blot AKT1 18359480 Leukemia Homo sapiens Inhibit Quercetin synergy Phosphorylation Biochem Pharmacol Acute promyelocytic leukemia cell NB4 Western blot AKT1 18172319 Brain-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Res Glioblastoma cell U-87 MG Western blot AKT1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute myelogenous leukemia cell KG-1 Western blot AKT1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Leukemia cell MM6 Western blot AKT1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot AKT1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Histiocytic lymphoma cell U-937 Western blot AKT1 28024471 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Dephosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Histiocytic lymphoma cell U-937 Western blot AKT1 27795556 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Leukemia Lymphoma cell DEL Western blot AKT1 27795556 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Leukemia Lymphoma cell SU-DHL-1 Western blot AKT1 27795556 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Leukemia Lymphoma cell SUP-M2 Western blot AKT1 27794399 Lung-cancer Homo sapiens Inhibit Pd173074 synergy Downregulation,Dephosphorylation Lung Cancer Lung cancer cell SK-MES-1 Western blot AKT1 27733358 Lymphoma Homo sapiens Inhibit - - Phosphorylation Blood Hodgkin lymphoma cell L1236 Western blot AKT1 27671604 Heart-toxicity Homo sapiens Induce - - Phosphorylation Sci Rep Aortic endothelial cell HAECs Western blot AKT1 27189198 Leukemia Homo sapiens Inhibit Vorinostat synergy Downregulation,Dephosphorylation J Int Med Res Acute promyelocytic leukemia cell NB4 Western blot AKT1 27010069 Leukemia Homo sapiens Inhibit - - Phosphorylation Sci Rep Acute promyelocytic leukemia cell HL-60 Western blot AKT1 27010069 Leukemia Homo sapiens Inhibit - - Phosphorylation Sci Rep Acute promyelocytic leukemia cell NB4 Western blot AKT1 26883975 Prostate-cancer Homo sapiens Inhibit - - Dephosphorylation Life Sci Prostate carcinoma cell LNCaP Western blot AKT1 26883975 Prostate-cancer Homo sapiens Inhibit - - Dephosphorylation Life Sci Prostate carcinoma cell PC-3 Western blot AKT1 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Dephosphorylation Mol Cell Endocrinol Breast cancer cell SK-BR-3 Western blot AKT1 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Dephosphorylation Mol Cell Endocrinol Breast cancer cell MDA-MB-231 Western blot AKT1 17332940 Myeloma Homo sapiens Inhibit - - Phosphorylation Int J Oncol Multiple myeloma cell IM-9 Western blot AKT1 17332940 Myeloma Homo sapiens Inhibit - - Dephosphorylation Int J Oncol Myeloma cell U266 Western blot AKT1 16904648 Gallbladder-cancer Homo sapiens Inhibit - - Dephosphorylation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell Western blot AKT1 16482209 Leukemia Homo sapiens Inhibit 17-AAG synergy Phosphorylation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot AKT1 16434995 Leukemia Homo sapiens Inhibit - - Dephosphorylation Br J Cancer Leukemia cell Jurkat Western blot AKT1 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Downregulation J Investig Med Myelodysplastic syndrome cell MUTZ-1 Western blot AKT1 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Downregulation J Investig Med Myelodysplastic syndrome cell SKM-1 Western blot AKT1 30554581 Laryngeal-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Hela carcinoma cell HEP-2 Western blot AKT1 30477221 Gastric-cancer Homo sapiens Inhibit - - Upregulation,Phosphorylation Int J Mol Sci Gastric cancer cell MGC-803 Western blot AKT1 30477221 Gastric-cancer Homo sapiens Inhibit - - Upregulation,Phosphorylation Int J Mol Sci Gastric adenocarcinoma cell SGC-7901 Western blot AKT1 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Phosphorylation,Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Western blot AKT1 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Oncotarget Acute myeloid leukemia cell MOLM14 Western blot AKT1 30213730 Leukemia Homo sapiens Inhibit - - Phosphorylation,Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot AKT1 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot AKT1 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Mol Cancer Ther Primary leukemia cell PRIMARY FLT3-ITD AML Western blot AKT1 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Testis carcinoma cell F9 Western blot AKT1 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot AKT1 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot AKT1 26540567 Leukemia Homo sapiens Inhibit - - Phosphorylation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot AKT1 26038719 Leukemia Homo sapiens Inhibit Vorinostat synergy Downregulation,Dephosphorylation PeerJ Chronic myelogenous leukemia cell K-562 Western blot AKT1 25758096 Leukemia Homo sapiens Inhibit Rapamycin synergy Upregulation,Phosphorylation Int J Hematol Histiocytic lymphoma cell U-937 Western blot AKT1 25577250 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Tumour Biol Chondrosarcoma cell SW 1353 Western blot AKT1 25506699 Leukemia Homo sapiens Inhibit Etomoxir synergy Phosphorylation PLoS One Acute promyelocytic leukemia cell HL-60 Western blot AKT1 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Dephosphorylation Cancer Lett Osteosarcoma cell HOS Western blot AKT1 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Dephosphorylation Cancer Lett Fibrosarcoma cell HT1080 Western blot AKT1 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Dephosphorylation Tumour Biol Hepatocellular carcinoma cell HEPG2 Western blot AKT1 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Dephosphorylation Tumour Biol Liver cancer cell Huh7 Western blot AKT1 25128771 Bone-toxicity Homo sapiens Induce - - Phosphorylation Environ Toxicol Pharmacol Osteoblasts cell HFOB1.19 Western blot AKT1 24969414 Gastric-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot AKT1 24791595 Leukemia Homo sapiens Inhibit - - Phosphorylation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot AKT1 24762191 Pulmonary-fibrosis Homo sapiens Inhibit - - Dephosphorylation Respir Res Normal human lung fibroblast NHLFs Western blot AKT1 24482137 Gastric-cancer Homo sapiens Inhibit - - Dephosphorylation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot AKT1 23980369 Myeloma Homo sapiens Inhibit Homoharringtonine synergy Dephosphorylation Zhongguo Zhong Xi Yi Jie He Za Zhi Myeloma cell RPMI 8226 Western blot AKT1 23700110 Myeloma Homo sapiens Inhibit Matrine synergy Dephosphorylation Planta Med Myeloma cell RPMI 8226 Western blot AKT1 23700110 Myeloma Homo sapiens Inhibit Matrine synergy Dephosphorylation Planta Med Myeloma cell U266 Western blot AKT1 23548265 Lung-cancer Homo sapiens Inhibit Erlotinib synergy Phosphorylation Mol Cancer Ther Lung adenocarcinoma cell A549 Western blot AKT1 23542114 Brain-cancer Homo sapiens Inhibit - - Dephosphorylation Toxicol Lett Cancer stem-like cell GBM neurospheres Western blot AKT1 23352504 Cervical-cancer Homo sapiens Inhibit Ly294002 synergy Phosphorylation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot AKT2 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR ALAS2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ALDH3A2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ALK1 18231732 Myeloma Homo sapiens Inhibit - - Downregulation J Huazhong Univ Sci Technolog Med Sci Myeloma cell RPMI 8226 Microarray analysis Alp 22465848 Bone-toxicity Rattus norvegicus Induce - - Downregulation Bone Primary osteoblast progenitor cell Mature asteoblast QRT-PCR, RT-PCR ALS2CR13 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Alt 16273603 Liver-cancer Rattus norvegicus Inhibit - - Downregulation World J Gastroenterol - - Kit Alt 17690699 Liver-toxicity Mus musculus Induce Trolox detoxicity Upregulation Leukemia Lymphoma cell P388 Western blot ALX4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AMH 25076250 Esophageal-cancer Homo sapiens Inhibit - - Downregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR AMH 25076250 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Tumori Colorectal cancer cell LS 174 QRT-PCR Ampk 32184170 Muscle-toxicity Mus musculus Induce - - Phosphorylation Toxicol In Vitro Myoblast cell C2C12 Western blot AMPK 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Dephosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell CCLP-1 Western blot AMPK 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Phosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot AMPK 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Dephosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell HCCC-9810 Western blot AMPK 25344585 Leukemia Homo sapiens Inhibit - - Phosphorylation,Dephosphorylation Mol Cancer Ther Histiocytic lymphoma cell U-937 Western blot AMPK 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Downregulation Pharmazie Acute promyelocytic leukemia cell HL-60 Western blot AMPK 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Upregulation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot ANGPT1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ANGPT2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ANKIB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ANKRD11 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ANKRD29 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ANNII 21223737 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR ANNII 19781379 Leukemia Homo sapiens Inhibit - - Downregulation Chin Med J (Engl) Bone marrow cell Bone marrow mononuclear cell QRT-PCR ANP32B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ANP32D 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ANXA1 18081892 Immune-toxicity Homo sapiens Induce - - Upregulation Br J Haematol Neutrophil cell Neutrophil IHC ANXA1 25983101 Esophageal-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Esophageal squamous carcinoma cell ECA109 RT-PCR,QRT-PCR ANXA1 25983101 Gastric-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Gastric adenocarcinoma cell SGC-7901 RT-PCR,QRT-PCR, Western blot ANXA1 25983101 Pancreas-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Pancreatic cancer cell BxPC-3 RT-PCR,QRT-PCR, Western blot ANXA1 25983101 Colorectal-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Colorectal cancer cell LS 174 RT-PCR,QRT-PCR, Western blot ANXA2 26051726 Leukemia Homo sapiens Inhibit Daunorubicin synergy Downregulation Pak J Pharm Sci Acute promyelocytic leukemia cell NB4 ELISA ANXA2 12165291 Leukemia Homo sapiens Inhibit - - Downregulation Thromb Res Acute promyelocytic leukemia cell NB4 RT-PCR ANXA2 12165291 Leukemia Homo sapiens Inhibit - - Downregulation Thromb Res Acute promyelocytic leukemia cell NB4 Western blot ANXA5 16166054 Brain-cancer Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Flow cytometry ANXA5 16166054 Brain-cancer Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Neuroblastoma cell SK-N-AS Flow cytometry ANXA5 16166054 Leukemia Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Flow cytometry ANXA6 28466809 Leukemia Homo sapiens Inhibit - - Upregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS ANXA7 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Kidney cancer cell CAKI-1 Western blot ANXA7 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Kidney cancer cell CAKI-2 Western blot ANXA7 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Renal cell adenocarcinoma cell 786-O Western blot ANXA7 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Renal cell adenocarcinoma cell ACHN Western blot AOC 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - Kit AOC3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis AP1 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical adenocarcinoma cell HeLa ELISA AP1 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell Ca Ski ELISA AP1 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell C-33A ELISA AP1 15494640 Bladder-cancer Homo sapiens Inhibit - - Downregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 EMSA AP3S1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Apaf1 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis APAF1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis APAF1 11172589 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Head and neck cancer cell PCI-1 Western blot APAF1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot APAF1 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot APBB1IP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis APC 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR APP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AQP9 23358330 Leukemia Homo sapiens Inhibit Realgar synergy Upregulation Biol Pharm Bull Chronic myelogenous leukemia cell K-562 QRT-PCR Ar 18630931 Reproductive-toxicity Mus musculus Induce - - Downregulation Chem Res Toxicol - - RT-PCR AR 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis Arc 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR ARF 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Upregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR ARF 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Upregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR ARF1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARFIP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARFIP2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Arg1 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Melanoma cell B16 RT-PCR Arg1 28454374 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Hepatoma cell Heptoma 22 RT-PCR ARHGAP21 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARHGAP5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARHGDIB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARID1B 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARK5 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARL10B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARL3 22898604 Leukemia Homo sapiens Inhibit - - Downregulation Blood Chronic myelogenous leukemia cell K-562 Western blot ARL3 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Upregulation Autophagy Fibrosarcoma cell HT1080 Western blot ARMC8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARMET 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARNT2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARRDC3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ARSA 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot ARSA 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot Art 29097844 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation J Toxicol Pathol - - Western blot AS3MT 31355259 Liver-toxicity Homo sapiens Induce Proanthocyanidins detoxicity Upregulation Biomed Res Int Embryo hepatocyte L-O2 ELISA AS3MT 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR AS3MT 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR AS3MT 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR AS3MT 24819152 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR ASAH1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ASAH2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ASB2 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR ASB5 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Asc 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis ASK1 17331470 Leukemia Homo sapiens Inhibit - - Phosphorylation Biochem Biophys Res Commun Acute promyelocytic leukemia cell NB4 Western blot ASK1 17331470 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Biochem Biophys Res Commun Chronic myelogenous leukemia cell K-562 Western blot ASl 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ASNA1 27736728 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot ASNA1 27736728 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot ASNA1 27736728 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR,Western blot ASNA1 27736728 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR,Western blot ASNS 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis ASNS 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis ASPM 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ASXL2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AT1A1 28466809 Leukemia Homo sapiens Inhibit - - Upregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS ATF2 12239215 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot ATF2 11454688 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Cancer Res Prostate carcinoma cell PC-3 Western blot ATF3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis ATF3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis ATF3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Atf4 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Atf4 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Atf4 27461142 Immune-toxicity Mus musculus Induce - - Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot Atf4 23892647 Vascular-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot ATF4 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis ATF4 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis ATF4 27655700 Liver-cancer Homo sapiens Inhibit Shikonin synergy Upregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot ATF4 23880367 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Auris Nasus Larynx Hela carcinoma cell HEP-2 Western blot ATF5 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute monocytic leukemia cell THP-1 QRT-PCR ATF5 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR, Western blot ATF5 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR, Western blot Atf6 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget - - Western blot Atf6 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Atf6 23892647 Vascular-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot ATF6 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis ATF6 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis ATF6 17963750 Posterior-capsule-opacification Homo sapiens Inhibit - - Upregulation Exp Eye Res Lens epithelial cell FHL 124 QRT-PCR ATF6 19878647 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Polymorphonuclear neutrophils cell Polymorphonuclear neutrophils RT-PCR ATF6 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell MUTZ-1 Western blot ATF6 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell SKM-1 Western blot ATF6 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot ATF6 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot ATF6 25107562 Heart-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Naunyn Schmiedebergs Arch Pharmacol Embryonic kidney cell HEK-293 Western blot ATF6 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Downregulation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 Western blot ATF7IP 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ATG101 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR ATG101 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR Atg12 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Atg12 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot ATG12 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR ATG12 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR ATG12 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR ATG12 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR ATG12 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell PC-3 Western blot ATG12 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell LNCaP Western blot Atg13 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Atg13 31605998 Development-toxicity Mus musculus Induce NaF detoxicity Upregulation Chemosphere - - QRT-PCR Atg14 32044640 Reproductive-toxicity Mus musculus Induce - - Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 QRT-PCR Atg3 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Atg3 31846860 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf Spermatogonial cell GC-1 QRT-PCR ATG4B 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot ATG4B 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot ATG4B 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot ATG4B 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot ATG4B 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATG5 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR ATG5 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot ATG5 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot ATG5 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot ATG5 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot ATG5 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATG5 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATG5 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATG5 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATG5 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot ATG5 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot ATG5 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot ATG5 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell LNCaP Western blot ATG5 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Downregulation PLoS One Prostate carcinoma cell PC-3 Western blot ATG5 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Osteosarcoma cell HOS Western blot ATG5 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Fibrosarcoma cell HT1080 Western blot Atg7 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Atg7 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR Atg7 32044640 Reproductive-toxicity Mus musculus Induce Rapamycin detoxicity Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 QRT-PCR, Western blot Atg7 32044640 Reproductive-toxicity Mus musculus Induce 3-MA detoxicity Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 Western blot ATG7 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR ATG7 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR ATG7 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot ATG7 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot ATGB 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATGB 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATGB 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot ATHL1 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Atm 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis ATM 28533173 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR ATM 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR ATM 26871293 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Oncotarget Glioma cell U87 Western blot ATP synthase beta 22093145 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Cancer Breast epithelial carcinoma cell T-47D Western blot ATP11A 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ATP11A 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ATP1A1 29274627 Lung-cancer Homo sapiens Inhibit - - Downregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 Kit Atp2a2 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Downregulation Oncotarget - - Kit Atp2a2 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Downregulation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Kit Atp2a2 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Downregulation Molecules Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Atp2a2 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Downregulation Molecules - - Western blot ATP2A2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ATP5I 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ATP6V1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ATP6V1C1 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR ATP6V1G1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ATPA 28466809 Leukemia Homo sapiens Inhibit - - Downregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS ATPASE 29274627 Lung-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 Kit ATPIF1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ATR 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot, IFA Atrogin1 32635466 Muscle-toxicity Mus musculus Induce - - Upregulation Molecules - - IHC Atrogin1 32184170 Muscle-toxicity Mus musculus Induce - - Upregulation Toxicol In Vitro Myoblast cell C2C12 Western blot ATTG5 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR ATXN2 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis AURKA 26871293 Brain-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation Oncotarget Glioma cell U87 Western blot AVIL 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis AZU1 26892147 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Life Sci Acute promyelocytic leukemia cell HL-60 QRT-PCR B1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis B4GALT5 18439752 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell SHG44 RT-PCR, Western blot B4GALT5 18439752 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell U87 Western blot B4GALT5 18439752 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell U251 Western blot B7-H4 26781180 Liver-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Hepatocellular carcinoma cell MHCC97H QRT-PCR, Western blot BACH1 29260515 Lung-cancer Homo sapiens Inhibit - - Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Lung adenocarcinoma cell A549 Western blot Bad 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis Bad 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Cell Physiol Biochem Heart myoblast H9C2 Western blot Bad 19141569 Liver-toxicity Rattus norvegicus Induce - - Downregulation Toxicol Ind Health Hepatocyte Hepatocytes Western blot BAD 31539632 Breast-cancer Homo sapiens Inhibit BKM120 synergy Upregulation Int J Biochem Cell Biol Breast cancer cell MCF7 QRT-PCR BAD 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR BAD 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR BAD 24161621 Brain-cancer Homo sapiens Inhibit U0126 synergy Upregulation Neurochem Int Neuroblastoma cell SK-N-BE(2) QRT-PCR BAD 16904648 Gallbladder-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell RT-PCR, Western blot BAD 23239002 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Dephosphorylation Chin J Integr Med Acute promyelocytic leukemia cell HL-60 Western blot BAD 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Upregulation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot BAD 19364129 Myeloma Homo sapiens Inhibit - - Upregulation J Proteome Res Myeloma cell U266 Western blot BAD 26629016 Leukemia Homo sapiens Inhibit Hyperoside synergy Dephosphorylation Int J Clin Exp Med Acute promyelocytic leukemia cell HL-60 Western blot BAD 16467208 Leukemia Homo sapiens Inhibit Pd184352 synergy Phosphorylation Blood Acute myelogenous leukemia cell AML blasts Western blot Bak 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Upregulation Exp Ther Med Leukemia cell WEHI-3 Western blot BAK 17530438 Brain-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis BAK 23529539 Myeloma Homo sapiens Inhibit Cryptotanshinone synergy Upregulation Metallomics Myeloma cell U266 Western blot BAK 28927142 Lung-cancer Homo sapiens Inhibit - - Upregulation Oncol Lett Lung cancer cell SW 900 Western blot BAK 19701692 Bone-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Osteosarcoma cell Saos-2 Western blot BAK 26680881 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Treat Acute promyelocytic leukemia cell HL-60 Western blot BAK 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot BAK 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot BAK 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot BAK 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot BAK 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot BAK 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot BAK 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell HCC4006 Western blot Bak1 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis BAK1 31442540 Liver-toxicity Gallus gallus Induce - - Upregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR,Western blot BAK1 24479808 Brain-cancer Homo sapiens Inhibit - - Upregulation Curr Pharm Des Glioma cell U251 QRT-PCR, Western blot BAMBI 25076250 Esophageal-cancer Homo sapiens Inhibit - - Upregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR BAPX1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BASP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis bax 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Environ Pollut - - Western blot bax 23121984 Liver-cancer Poeciliopsis lucida Inhibit - - Upregulation Chemosphere Hepatocellular carcinoma cell PLHC-1 Western blot Bax 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Upregulation Biomed Pharmacother Heart myoblast H9C2 Kit Bax 19260322 Reproductive-toxicity Rattus norvegicus Induce - - Upregulation Zhongguo Zhong Yao Za Zhi - - IHC Bax 12609071 Vascular-disease Rattus norvegicus Inhibit - - Upregulation Chin Med J (Engl) Ascular smooth muscle cell VSMCs IHC Bax 10712780 Liver-cancer Mus musculus Inhibit - - Upregulation Zhonghua Gan Zang Bing Za Zhi Hepatocellular carcinoma cell HEPA IHC Bax 31258454 Development-toxicity Rattus norvegicus Induce - - Upregulation Dose Response - - QRT-PCR Bax 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Upregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR Bax 23892647 Vascular-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR Bax 25787108 Neuronal-toxicity Mus musculus Induce - - Upregulation J Occup Health - - QRT-PCR,Western blot Bax 32096187 Heart-toxicity Rattus norvegicus Induce - - Upregulation Eur Rev Med Pharmacol Sci Ventricular cardiomyocyte H9c2 QRT-PCR, Western blot Bax 31718892 Lymphoma Homo sapiens Inhibit - - Upregulation Bioorg Chem Burkitt's lymphoma cell Raji QRT-PCR, Western blot Bax 28454374 Skin-cancer Mus musculus Inhibit - - Upregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell RT-PCR Bax 19141569 Liver-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Ind Health Hepatocyte Hepatocytes RT-PCR, Western blot Bax 23542815 Heart-toxicity Cavia porcellus Induce - - Upregulation Toxicol Lett Cardiac fibroblast Cardiac fibroblasts Western blot Bax 23542815 Heart-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Lett Neonatal cardiac fibroblast NRCF Western blot Bax 31632492 Leukemia Homo sapiens Inhibit Resveratrol synergy Upregulation J Cancer Chronic myelogenous leukemia cell K-562 Western blot Bax 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Cell Physiol Biochem Heart myoblast H9C2 Western blot Bax 23201927 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Toxicol Lett Heart myoblast H9C2 Western blot Bax 22622864 Muscle-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Myoblast cell C2C12 Western blot Bax 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Bax 27561292 Liver-toxicity Rattus norvegicus Induce Allicin detoxicity Upregulation Biol Trace Elem Res - - Western blot Bax 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Upregulation Biomed Pharmacother - - Western blot Bax 29610575 Brain-cancer Rattus norvegicus Inhibit - - Upregulation Cell Mol Biol Lett Glioma cell C6 Western blot Bax 29610575 Brain-cancer Rattus norvegicus Inhibit - - Upregulation Cell Mol Biol Lett Gliosarcoma cell 9L/lacZ Western blot Bax 23662152 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Upregulation Evid Based Complement Alternat Med - - Western blot Bax 23337567 Bone-cancer Rattus norvegicus Inhibit - - Downregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot Bax 25123535 Pulmonary-fibrosis Rattus norvegicus Inhibit - - Downregulation Life Sci - - Western blot, IHC BAX 19208092 Leukemia Homo sapiens Inhibit - - Downregulation Int J Lab Hematol Peripheral blood mononuclear cell Peripheral blood mononuclear Flow cytometry BAX 11819674 Liver-cancer Homo sapiens Inhibit - - Upregulation World J Gastroenterol Liver cancer cell BEL-7402 Flow cytometry BAX 31534777 Breast-cancer Homo sapiens Inhibit - - Upregulation Future Sci OA Breast cancer cell MCF7 IFA BAX 20403207 Gastric-cancer Homo sapiens Inhibit - - Upregulation World J Surg Oncol Gastric adenocarcinoma cell SGC-7901 IFA BAX 11135700 Liver-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Gan Zang Bing Za Zhi Hepatocarcinoma cell QGY-7701 IHC BAX 24908354 Leukemia Homo sapiens Inhibit Deferoxamine synergy Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 IHC, IFA BAX 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BAX 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis BAX 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR BAX 29164574 Brain-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Glioma cell U87 QRT-PCR BAX 28459147 Brain-cancer Homo sapiens Inhibit Radiation synergy Upregulation Iran Biomed J Glioblastoma cell U-87 MG QRT-PCR BAX 27427852 Breast-cancer Homo sapiens Inhibit Melatonin synergy Upregulation Biomed Pharmacother Breast cancer cell MCF7 QRT-PCR BAX 27039805 Brain-cancer Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR BAX 30600718 Leukemia Homo sapiens Inhibit - - Upregulation Artif Cells Nanomed Biotechnol Acute promyelocytic leukemia cell NB4 QRT-PCR BAX 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR BAX 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR BAX 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR BAX 29571380 Liver-toxicity Dicentrarchus labrax Induce - - Upregulation Mar Pollut Bull - - QRT-PCR BAX 24161621 Brain-cancer Homo sapiens Inhibit U0126 synergy Upregulation Neurochem Int Neuroblastoma cell SK-N-BE(2) QRT-PCR BAX 23968587 Brain-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Glioblastoma cell U-87 MG QRT-PCR BAX 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Upregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR BAX 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot BAX 31442540 Liver-toxicity Gallus gallus Induce - - Upregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR,Western blot BAX 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot BAX 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot BAX 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot BAX 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot BAX 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot BAX 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot BAX 16882451 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Acute lymphoblastic leukemia cell MOLT-4 QRT-PCR, Western blot BAX 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Lymphoma cell Kappas299 QRT-PCR, Western blot BAX 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot BAX 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell Jurkat QRT-PCR, Western blot BAX 23382965 Gastric-cancer Homo sapiens Inhibit - - Upregulation PLoS One Gastric cancer cell FU97 QRT-PCR, Western blot BAX 27665715 Leukemia Homo sapiens Inhibit Triptolide synergy Upregulation Mol Med Rep Myelodysplastic syndrome cell SKM-1 RT-PCR BAX 26883975 Prostate-cancer Homo sapiens Inhibit - - Upregulation Life Sci Prostate carcinoma cell PC-3 RT-PCR BAX 26117010 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR BAX 16904648 Gallbladder-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell RT-PCR, Western blot BAX 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Upregulation PLoS One Acute promyelocytic leukemia cell NB4 RT-PCR, Western blot BAX 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Upregulation PLoS One Primary acute promyelocytic leukemia cell Primary APL cell RT-PCR, Western blot BAX 25815518 Myeloma Homo sapiens Inhibit Valproic Acid synergy Upregulation Mol Med Rep Myeloma cell RPMI 8226 RT-PCR, Western blot BAX 25130820 Myeloma Homo sapiens Inhibit Valproic Acid synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell RPMI 8226 RT-PCR, Western blot BAX 24738333 Lymphoma Homo sapiens Inhibit Doxorubicin synergy Upregulation J Biomed Nanotechnol Burkitt's lymphoma cell Raji RT-PCR, Western blot BAX 23660868 Leukemia Homo sapiens Inhibit Vitamin-D3 synergy Upregulation Oncol Rep Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot BAX 23660868 Leukemia Homo sapiens Inhibit Vitamin-D3 synergy Upregulation Oncol Rep Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot BAX 23529539 Myeloma Homo sapiens Inhibit Cryptotanshinone synergy Upregulation Metallomics Myeloma cell U266 Western blot BAX 32952848 Bladder-cancer Homo sapiens Inhibit - - Upregulation Oxid Med Cell Longev Bladder carcinoma cell T24 Western blot BAX 31218953 Colorectal-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Curr Pharm Des Colorectal carcinoma cell HCT116 Western blot BAX 29138840 Liver-cancer Homo sapiens Inhibit - - Upregulation Mol Med Rep Hepatocellular carcinoma cell HEPG2 Western blot BAX 31079498 Tongue-cancer Homo sapiens Inhibit - - Upregulation Artif Cells Nanomed Biotechnol Oral squamous cell carcinoma cell Tca-8113 Western blot BAX 28966729 Colorectal-cancer Homo sapiens Inhibit - - Upregulation J Cancer Sci Ther Colorectal adenocarcinoma cell HT-29 Western blot BAX 28823259 Leukemia Homo sapiens Inhibit Itraconazole synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot BAX 28467781 Lung-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Lung cancer cell NCI-H1299 Western blot BAX 28446277 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot BAX 28239804 Gastric-cancer Homo sapiens Inhibit - - Upregulation Eur Rev Med Pharmacol Sci Gastric adenocarcinoma cell BGC823 Western blot BAX 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Downregulation Int J Oncol Liver cancer cell BEL-7402 Western blot BAX 21779797 Lung-toxicity Homo sapiens Induce - - Upregulation Mol Biol Rep Pulmonary fibroblast Human pulmonary fibroblast Western blot BAX 21741957 Leukemia Homo sapiens Inhibit Irradiation synergy Upregulation Chem Biol Interact Acute promyelocytic leukemia cell HL-60 Western blot BAX 21418039 Liver-cancer Homo sapiens Inhibit - - Upregulation Cell Biol Int Hepatocellular carcinoma cell SMMC-7721 Western blot BAX 21061466 Melanoma Homo sapiens Inhibit - - Upregulation Am J Chin Med Uveal melanoma cell SP6.5 Western blot BAX 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Multiple myeloma cell KMS28PE Western blot BAX 20605902 Leukemia Homo sapiens Inhibit Curcumin synergy Upregulation J Pharmacol Exp Ther Histiocytic lymphoma cell U-937 Western blot BAX 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Hepatocellular carcinoma cell HEPG2 Western blot BAX 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Hepatocellular carcinoma cell HEP3B Western blot BAX 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Liver adenocarcinoma cell SK-HEP-1 Western blot BAX 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Upregulation Autophagy Fibrosarcoma cell HT1080 Western blot BAX 20164150 Leukemia Homo sapiens Inhibit - - Upregulation Ann Oncol Leukemia cell Promyelocyte cell Western blot BAX 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Upregulation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot BAX 19664237 Lung-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation J Exp Clin Cancer Res Large cell lung cancer cell H460 Western blot BAX 19489279 Gastric-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Yi Xue Za Zhi Coronary smooth muscle cell HCSMC Western blot BAX 19364129 Myeloma Homo sapiens Inhibit - - Upregulation J Proteome Res Myeloma cell U266 Western blot BAX 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-1906 Western blot BAX 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-2020 Western blot BAX 18695917 Cervical-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Cervical adenocarcinoma cell HeLa Western blot BAX 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-1 Western blot BAX 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Downregulation Blood Myeloma cell OPM2 Western blot BAX 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-6 Western blot BAX 18412143 Cervical-cancer Homo sapiens Inhibit - - Upregulation J Cell Physiol Cervical adenocarcinoma cell HeLa Western blot BAX 27655700 Liver-cancer Homo sapiens Inhibit Shikonin synergy Upregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot BAX 27498627 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Chronic myelogenous leukemia cell K-562 Western blot BAX 27498627 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Acute promyelocytic leukemia cell NB4 Western blot BAX 26883975 Prostate-cancer Homo sapiens Inhibit - - Upregulation Life Sci Prostate carcinoma cell LNCaP Western blot BAX 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot BAX 26772155 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Chem Biol Interact Lung adenocarcinoma cell A549 Western blot BAX 17390014 Cervical-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Cervix squamous cell carcinoma cell SiHa Western blot BAX 17374990 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot BAX 17300860 Brain-cancer Homo sapiens Inhibit Lipoic-acid detoxicity Downregulation Food Chem Toxicol Glioblastoma cell U118 Western blot BAX 17237268 Leukemia Homo sapiens Inhibit Phytosphingosine synergy Downregulation Mol Cancer Ther Histiocytic lymphoma cell U-937 Western blot BAX 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Western blot BAX 16972261 Leukemia Homo sapiens Inhibit U0126 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot BAX 16972261 Leukemia Homo sapiens Inhibit SP600125 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot BAX 16685442 Lung-cancer Homo sapiens Inhibit Sulindac synergy Downregulation Int J Oncol Lung cancer cell NCI-H157 Western blot BAX 16467208 Leukemia Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Acute myelogenous leukemia cell AML blasts Western blot BAX 30668372 Neuronal-toxicity Homo sapiens Induce Thymoquinone detoxicity Upregulation Phytomedicine Neuroblastoma cell SH-SY5Y Western blot BAX 30554581 Laryngeal-cancer Homo sapiens Inhibit - - Upregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Hela carcinoma cell HEP-2 Western blot BAX 30333888 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Lett Burkitt's lymphoma cell Raji Western blot BAX 30333888 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Lett Leukemia cell Jurkat Western blot BAX 16020671 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Neuroblastoma cell SK-N-BE(2)C Western blot BAX 15781666 Leukemia Homo sapiens Inhibit 19-nor-1,25(oh)-2-d-2 synergy Upregulation Cancer Res Acute promyelocytic leukemia cell HL-60 Western blot BAX 15538402 Leukemia Homo sapiens Inhibit Pd98059 synergy Upregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot BAX 12939460 Immune-toxicity Homo sapiens Induce - - Upregulation Mol Cancer Ther Normal peripheral blood cell T cell Western blot BAX 12883267 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Pancreas Pancreatic cancer cell MIA PaCa-2 Western blot BAX 11172589 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Head and neck cancer cell PCI-1 Western blot BAX 10850458 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Res Myeloma cell MC/CAR Western blot BAX 26579413 Liver-cancer Homo sapiens Inhibit N-(beta-elemene-13-yl)tryptophan-methyl-ester synergy Upregulation Acta Pharm Sin B Hepatocellular carcinoma cell SMMC-7721 Western blot BAX 26524030 Lymphoma Homo sapiens Inhibit Adriamycin synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji Western blot BAX 26494474 Head-and-neck-cancer Homo sapiens Inhibit Dithiothreitol synergy Upregulation Environ Toxicol Oral cancer cell Primarily cultured cell Western blot BAX 25972196 Liver-cancer Homo sapiens Inhibit - - Upregulation J Toxicol Sci Hepatocellular carcinoma cell HEPG2 Western blot BAX 25932150 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Clin Exp Med Hepatocellular carcinoma cell HEPG2 Western blot BAX 25577250 Bone-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot BAX 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Upregulation Tumour Biol Liver cancer cell Huh7 Western blot BAX 25338570 Leukemia Homo sapiens Inhibit Curcumin synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot BAX 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot BAX 25128771 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Pharmacol Osteoblasts cell HFOB1.19 Western blot BAX 24993472 Leukemia Homo sapiens Inhibit - - Upregulation Acta Haematol Chronic myelogenous leukemia cell K-562 Western blot BAX 24969414 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot BAX 24956101 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Leukemia cell MEC-1 Western blot BAX 24944602 Leukemia Homo sapiens Inhibit - - Upregulation Exp Ther Med Acute monocytic leukemia cell THP-1 Western blot BAX 24884809 Liver-cancer Homo sapiens Inhibit Nutlin-3 synergy Upregulation Mol Cancer Hepatocellular carcinoma cell HEPG2 Western blot BAX 24884809 Liver-cancer Homo sapiens Inhibit Nutlin-3 synergy Upregulation Mol Cancer Hepatocellular carcinoma cell SMMC-7721 Western blot BAX 24666483 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot BAX 24482137 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot BAX 24356076 Leukemia Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Acute promyelocytic leukemia cell NB4 Western blot BAX 24356076 Leukemia Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Acute promyelocytic leukemia cell HL-60 Western blot BAX 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot BAX 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot BCAT2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis BCHE 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Bcl-xL 18546268 Leukemia Homo sapiens Inhibit Genistein synergy Downregulation Int J Cancer Histiocytic lymphoma cell U-937 Western blot BCL-XL 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR BCL-XL 22391178 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell KM3 RT-PCR BCL-XL 15498110 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR BCL-XL 16904648 Gallbladder-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell RT-PCR, Western blot BCL-XL 23178716 Ovary-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Ovarian carcinoma cell HEY Western blot BCL-XL 23082001 Leukemia Homo sapiens Inhibit Ethacrynic-acid synergy Upregulation Clin Cancer Res Acute promyelocytic leukemia cell HL-60 Western blot BCL-XL 23082001 Leukemia Homo sapiens Inhibit Ethacrynic-acid synergy Upregulation Clin Cancer Res Chronic myelogenous leukemia cell K-562 Western blot BCL-XL 20953137 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Multiple myeloma cell KMS28PE Western blot BCL-XL 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Downregulation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot BCL-XL 19701692 Bone-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Osteosarcoma cell Saos-2 Western blot BCL-XL 19701692 Bone-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Osteosarcoma cell Saos-2 Western blot BCL-XL 19159621 Leukemia Homo sapiens Inhibit - - Downregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot BCL-XL 18359480 Leukemia Homo sapiens Inhibit Quercetin synergy Upregulation Biochem Pharmacol Histiocytic lymphoma cell U-937 Western blot BCL-XL 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell U266 Western blot BCL-XL 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell RPMI 8226 Western blot BCL-XL 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell MM.1S Western blot BCL-XL 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Multiple myeloma cell KMS-11 Western blot BCL-XL 17568816 Lymphoma Homo sapiens Inhibit Interferon-alpha synergy Downregulation Leukemia Lymphoma cell BC-3 Western blot BCL-XL 28024471 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Histiocytic lymphoma cell U-937 Western blot BCL-XL 26883975 Prostate-cancer Homo sapiens Inhibit - - Downregulation Life Sci Prostate carcinoma cell LNCaP Western blot BCL-XL 26883975 Prostate-cancer Homo sapiens Inhibit - - Downregulation Life Sci Prostate carcinoma cell PC-3 Western blot BCL-XL 16685442 Lung-cancer Homo sapiens Inhibit Sulindac synergy Downregulation Int J Oncol Lung cancer cell NCI-H157 Western blot BCL-XL 29738779 Liver-cancer Homo sapiens Inhibit - - Downregulation Life Sci Hepatocellular carcinoma cell HEP3B Western blot BCL-XL 29738779 Liver-toxicity Homo sapiens Induce - - Downregulation Life Sci Liver cell Chang liver cell Western blot BCL-XL 16105982 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute myeloid leukemia cell ML1 Western blot BCL-XL 15538402 Leukemia Homo sapiens Inhibit Pd98059 synergy Upregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot BCL-XL 15291359 Leukemia Homo sapiens Inhibit Phenylarsine-oxide synergy Upregulation Leuk Lymphoma Acute promyelocytic leukemia cell NB4 Western blot BCL-XL 14559676 Lymphoma Homo sapiens Inhibit - - Downregulation Di Yi Jun Yi Da Xue Xue Bao Burkitt's lymphoma cell Raji Western blot BCL-XL 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot BCL-XL 11739184 Lymphoma Homo sapiens Inhibit - - Downregulation Blood HTLV-1-transformed cell C8166 Western blot BCL-XL 25577250 Bone-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot BCL-XL 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Downregulation Tumour Biol Liver cancer cell Huh7 Western blot BCL-XL 24944602 Leukemia Homo sapiens Inhibit - - Downregulation Exp Ther Med Acute monocytic leukemia cell THP-1 Western blot BCL-XL 23980369 Myeloma Homo sapiens Inhibit Homoharringtonine synergy Downregulation Zhongguo Zhong Xi Yi Jie He Za Zhi Myeloma cell RPMI 8226 Western blot BCL-XL 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell SMMC-7721 Western blot BCL-XL 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell HEPG2 Western blot BCL-XL 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Downregulation Cancer Biol Ther Kidney cancer cell CAKI-1 Western blot BCL-XL 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell 143B Western blot BCL-XL 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell Saos-2 Western blot BCL-XL 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell U-2 OS Western blot BCL-XL 23770046 Ovary-cancer Homo sapiens Inhibit - - Downregulation Biochim Biophys Acta Ovarian cancer cell SK-OV-3 Western blot BCL-XL 23337567 Bone-cancer Homo sapiens Inhibit - - Downregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot BCL-XL 23337567 Bone-cancer Homo sapiens Inhibit - - Downregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot bcl2 27736677 Liver-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR bcl2 27736677 Kidney-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR bcl2 24905690 Immune-toxicity Danio rerio Induce - - Downregulation Ecotoxicol Environ Saf - - QRT-PCR bcl2 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Environ Pollut - - Western blot bcl2 23121984 Liver-cancer Poeciliopsis lucida Inhibit - - Downregulation Chemosphere Hepatocellular carcinoma cell PLHC-1 Western blot Bcl2 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother Heart myoblast H9C2 Kit Bcl2 19260322 Reproductive-toxicity Rattus norvegicus Induce - - Downregulation Zhongguo Zhong Yao Za Zhi - - IHC Bcl2 12609071 Vascular-disease Rattus norvegicus Inhibit - - Downregulation Chin Med J (Engl) Ascular smooth muscle cell VSMCs IHC Bcl2 10712780 Liver-cancer Mus musculus Inhibit - - Downregulation Zhonghua Gan Zang Bing Za Zhi Hepatocellular carcinoma cell HEPA IHC Bcl2 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Downregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR Bcl2 31605998 Development-toxicity Mus musculus Induce NaF detoxicity Downregulation Chemosphere - - QRT-PCR,Western blot Bcl2 25787108 Neuronal-toxicity Mus musculus Induce - - Downregulation J Occup Health - - QRT-PCR,Western blot Bcl2 33352257 Liver-toxicity Mus musculus Induce Rapamycin detoxicity Downregulation In Vitro Normal hepatocyte AML12 QRT-PCR, Western blot Bcl2 32781346 Reproductive-toxicity Mus musculus Induce - - Downregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot Bcl2 32096187 Heart-toxicity Rattus norvegicus Induce - - Downregulation Eur Rev Med Pharmacol Sci Ventricular cardiomyocyte H9c2 QRT-PCR, Western blot Bcl2 29297235 Heart-toxicity Rattus norvegicus Induce L-ascorbic-acid detoxicity Downregulation Toxicol Mech Methods Heart myoblast H9C2 RT-PCR Bcl2 29297235 Heart-toxicity Rattus norvegicus Induce Alpha-tocopherol detoxicity Downregulation Toxicol Mech Methods Heart myoblast H9C2 RT-PCR Bcl2 19141569 Liver-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Ind Health Hepatocyte Hepatocytes RT-PCR, Western blot Bcl2 23542815 Heart-toxicity Cavia porcellus Induce - - Downregulation Toxicol Lett Cardiac fibroblast Cardiac fibroblasts Western blot Bcl2 23542815 Heart-toxicity Rattus norvegicus Induce - - Downregulation Toxicol Lett Neonatal cardiac fibroblast NRCF Western blot Bcl2 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Downregulation Exp Ther Med Leukemia cell WEHI-3 Western blot Bcl2 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Downregulation Cell Physiol Biochem Heart myoblast H9C2 Western blot Bcl2 23201927 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Downregulation Toxicol Lett Heart myoblast H9C2 Western blot Bcl2 22622864 Muscle-toxicity Mus musculus Induce - - Downregulation Arch Toxicol Myoblast cell C2C12 Western blot Bcl2 19066063 Brain-cancer Rattus norvegicus Inhibit - - Downregulation Zhongguo Zhong Yao Za Zhi Glioma cell C6 Western blot Bcl2 18349030 Skin-cancer Mus musculus Inhibit - - Downregulation Ann Oncol Sezary Syndrome cell HuT 78 Western blot Bcl2 18349030 Skin-cancer Mus musculus Inhibit - - Downregulation Ann Oncol Cutaneous t-cell lymphoma cell MyLa 2059 Western blot Bcl2 17507598 Kidney-cancer Mus musculus Inhibit - - Downregulation Am J Physiol Renal Physiol Kidney cell AS4.1 Western blot Bcl2 29610575 Brain-cancer Rattus norvegicus Inhibit - - Downregulation Cell Mol Biol Lett Glioma cell C6 Western blot Bcl2 29610575 Brain-cancer Rattus norvegicus Inhibit - - Downregulation Cell Mol Biol Lett Gliosarcoma cell 9L/lacZ Western blot Bcl2 25123535 Pulmonary-fibrosis Rattus norvegicus Inhibit - - Upregulation Life Sci - - Western blot Bcl2 23662152 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Downregulation Evid Based Complement Alternat Med - - Western blot Bcl2 25268089 Brain-cancer Rattus norvegicus Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Glioma cell C6 Western blot, IHC BCL2 20369471 Leukemia Homo sapiens Inhibit Tanshinone-ii-a synergy Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Acute promyelocytic leukemia cell NB4 Flow cytometry BCL2 19208092 Leukemia Homo sapiens Inhibit - - Downregulation Int J Lab Hematol Peripheral blood mononuclear cell Peripheral blood mononuclear Flow cytometry BCL2 15844663 Lung-cancer Homo sapiens Inhibit - - Downregulation J Exp Ther Oncol Lung cancer cell PG Flow cytometry BCL2 15352174 Breast-cancer Homo sapiens Inhibit - - Downregulation J Cell Biochem Breast cancer cell MCF7 Flow cytometry BCL2 11877007 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Flow cytometry BCL2 11819674 Liver-cancer Homo sapiens Inhibit - - Upregulation World J Gastroenterol Liver cancer cell BEL-7402 Flow cytometry BCL2 11589617 Lymphoma Homo sapiens Inhibit - - Downregulation Cell Biol Int Burkitt's lymphoma cell Raji Flow cytometry BCL2 9737686 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute promyelocytic leukemia cell NB4 Flow cytometry BCL2 9737686 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Myeloma cell NOP-1 Flow cytometry BCL2 9737686 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute myeloid leukemia cell NKM-1 Flow cytometry BCL2 21473291 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Res Burkitt's lymphoma cell Raji Kit,QRT-PCR BCL2 21473291 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Res Burkitt's lymphoma cell NAMALWA Kit,QRT-PCR BCL2 18357729 Asthma Homo sapiens Inhibit - - Downregulation Yao Xue Xue Bao Peripheral blood cell T cell IFA, ELISA BCL2 20723295 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 IHC BCL2 19673332 Gastric-cancer Homo sapiens Inhibit - - Downregulation Zhongguo Zhong Xi Yi Jie He Za Zhi Gastric adenocarcinoma cell SGC-7901 IHC BCL2 12490120 Lung-cancer Homo sapiens Inhibit - - Downregulation Zhonghua Jie He He Hu Xi Za Zhi Small cell lung cancer cell NEI-H IHC BCL2 11780464 Bladder-cancer Homo sapiens Inhibit - - Downregulation Chin Med J (Engl) Bladder carcinoma cell BIU-87 IHC BCL2 11135700 Liver-cancer Homo sapiens Inhibit - - Downregulation Zhonghua Gan Zang Bing Za Zhi Hepatocarcinoma cell QGY-7701 IHC BCL2 24833880 Gastric-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol - - IHC BCL2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BCL2 15622746 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Northern blot, Western blot BCL2 8704214 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute promyelocytic leukemia cell NB4 Northern blot, Western blot BCL2 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR BCL2 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR BCL2 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR BCL2 31539632 Breast-cancer Homo sapiens Inhibit BKM120 synergy Downregulation Int J Biochem Cell Biol Breast cancer cell MCF7 QRT-PCR BCL2 31442540 Liver-toxicity Gallus gallus Induce - - Downregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR BCL2 28459147 Brain-cancer Homo sapiens Inhibit Radiation synergy Downregulation Iran Biomed J Glioblastoma cell U-87 MG QRT-PCR BCL2 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR BCL2 27784375 Myeloma Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell NCI-H929 QRT-PCR BCL2 27427852 Breast-cancer Homo sapiens Inhibit Melatonin synergy Downregulation Biomed Pharmacother Breast cancer cell MCF7 QRT-PCR BCL2 30600718 Leukemia Homo sapiens Inhibit - - Upregulation Artif Cells Nanomed Biotechnol Acute promyelocytic leukemia cell NB4 QRT-PCR BCL2 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR BCL2 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR BCL2 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR BCL2 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR BCL2 29571380 Liver-toxicity Dicentrarchus labrax Induce - - Downregulation Mar Pollut Bull - - QRT-PCR BCL2 25945059 Colorectal-cancer Homo sapiens Inhibit Ly294002 synergy Downregulation Onco Targets Ther Colorectal adenocarcinoma cell HT-29 QRT-PCR BCL2 23968587 Brain-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Glioblastoma cell U-87 MG QRT-PCR BCL2 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR BCL2 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR BCL2 23293885 Leukemia Homo sapiens Inhibit BIBR1532 synergy Downregulation Anticancer Agents Med Chem Acute promyelocytic leukemia cell NB4 QRT-PCR BCL2 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot BCL2 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Chemosphere - - QRT-PCR,Western blot BCL2 30339249 Heart-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - QRT-PCR,Western blot BCL2 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - QRT-PCR,Western blot BCL2 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot BCL2 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot BCL2 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR, Western blot BCL2 31718892 Lymphoma Homo sapiens Inhibit - - Downregulation Bioorg Chem Burkitt's lymphoma cell Raji QRT-PCR, Western blot BCL2 22959511 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot BCL2 22959511 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot BCL2 25110043 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Burkitt's lymphoma cell Raji QRT-PCR, Western blot BCL2 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Lymphoma cell Kappas299 QRT-PCR, Western blot BCL2 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot BCL2 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell Jurkat QRT-PCR, Western blot BCL2 23382965 Gastric-cancer Homo sapiens Inhibit - - Downregulation PLoS One Gastric cancer cell FU97 QRT-PCR, Western blot BCL2 32154163 Leukemia Homo sapiens Inhibit L-ascorbic-acid synergy Downregulation Front Oncol Acute promyelocytic leukemia cell HL-60 RT-PCR BCL2 32154163 Leukemia Homo sapiens Inhibit Alpha-tocopherol synergy Downregulation Front Oncol Acute promyelocytic leukemia cell HL-60 RT-PCR BCL2 22519831 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Mech Methods Chronic myelogenous leukemia cell K-562 RT-PCR BCL2 22519831 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Mech Methods Chronic myelogenous leukemia cell K-562 RT-PCR BCL2 20416161 Leukemia Homo sapiens Inhibit Flavonoids-of-puerarin synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR BCL2 20377131 Liver-cancer Homo sapiens Inhibit - - Downregulation Oncol Res Hepatocellular carcinoma cell HEPG2 RT-PCR BCL2 27665715 Leukemia Homo sapiens Inhibit Triptolide synergy Downregulation Mol Med Rep Myelodysplastic syndrome cell SKM-1 RT-PCR BCL2 29697268 Liver-toxicity Homo sapiens Induce L-ascorbic-acid detoxicity Downregulation Nutr Cancer Liver cell Chang liver cell RT-PCR BCL2 29697268 Liver-toxicity Homo sapiens Induce Alpha-tocopherol detoxicity Downregulation Nutr Cancer Liver cell Chang liver cell RT-PCR BCL2 14966945 Myelodysplastic-syndrome Homo sapiens Inhibit - - Downregulation Zhejiang Da Xue Xue Bao Yi Xue Ban Myelodysplastic syndrome cell MUTZ-1 RT-PCR BCL2 26117010 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR BCL2 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell MDA-MB-231 RT-PCR, Western blot BCL2 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell MCF7 RT-PCR, Western blot BCL2 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell SK-BR-3 RT-PCR, Western blot BCL2 22922982 Breast-cancer Homo sapiens Inhibit 89-strontium-chloride synergy Downregulation Oncol Rep Breast cancer cell MCF7 RT-PCR, Western blot BCL2 18726487 Cervical-cancer Homo sapiens Inhibit - - Downregulation Sci China C Life Sci Cervical adenocarcinoma cell HeLa RT-PCR, Western blot BCL2 16966277 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot BCL2 16904648 Gallbladder-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell RT-PCR, Western blot BCL2 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Downregulation PLoS One Acute promyelocytic leukemia cell NB4 RT-PCR, Western blot BCL2 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Downregulation PLoS One Primary acute promyelocytic leukemia cell Primary APL cell RT-PCR, Western blot BCL2 25815518 Myeloma Homo sapiens Inhibit Valproic Acid synergy Downregulation Mol Med Rep Myeloma cell RPMI 8226 RT-PCR, Western blot BCL2 25130820 Myeloma Homo sapiens Inhibit Valproic Acid synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell RPMI 8226 RT-PCR, Western blot BCL2 24738333 Lymphoma Homo sapiens Inhibit Doxorubicin synergy Downregulation J Biomed Nanotechnol Burkitt's lymphoma cell Raji RT-PCR, Western blot BCL2 23660868 Leukemia Homo sapiens Inhibit Vitamin-D3 synergy Downregulation Oncol Rep Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot BCL2 23660868 Leukemia Homo sapiens Inhibit Vitamin-D3 synergy Downregulation Oncol Rep Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot BCL2 23529539 Myeloma Homo sapiens Inhibit Cryptotanshinone synergy Upregulation Metallomics Myeloma cell U266 Western blot BCL2 32952848 Bladder-cancer Homo sapiens Inhibit - - Downregulation Oxid Med Cell Longev Bladder carcinoma cell T24 Western blot BCL2 29214213 Liver-cancer Homo sapiens Inhibit - - Downregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Western blot BCL2 31218953 Colorectal-cancer Homo sapiens Inhibit Resveratrol synergy Downregulation Curr Pharm Des Colorectal carcinoma cell HCT116 Western blot BCL2 29138840 Liver-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Hepatocellular carcinoma cell HEPG2 Western blot BCL2 31079498 Tongue-cancer Homo sapiens Inhibit - - Downregulation Artif Cells Nanomed Biotechnol Oral squamous cell carcinoma cell Tca-8113 Western blot BCL2 28980872 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Breast cancer cell MCF7 Western blot BCL2 28980872 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Breast cancer cell SK-BR-3 Western blot BCL2 28966729 Colorectal-cancer Homo sapiens Inhibit - - Upregulation J Cancer Sci Ther Colorectal adenocarcinoma cell HT-29 Western blot BCL2 28927142 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung cancer cell SW 900 Western blot BCL2 28927142 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung cancer cell SK-MES-1 Western blot BCL2 28823259 Leukemia Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot BCL2 28446277 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot BCL2 28239804 Gastric-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Gastric adenocarcinoma cell BGC823 Western blot BCL2 22751450 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot BCL2 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell LNCaP Western blot BCL2 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Downregulation PLoS One Prostate carcinoma cell PC-3 Western blot BCL2 22093145 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Cancer Breast epithelial carcinoma cell T-47D Western blot BCL2 21971985 Leukemia Homo sapiens Inhibit - - Downregulation Int J Mol Med Chronic myelogenous leukemia cell K-562 Western blot BCL2 21779797 Lung-toxicity Homo sapiens Induce - - Downregulation Mol Biol Rep Pulmonary fibroblast Human pulmonary fibroblast Western blot BCL2 21418039 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Int Hepatocellular carcinoma cell SMMC-7721 Western blot BCL2 21061466 Melanoma Homo sapiens Inhibit - - Downregulation Am J Chin Med Uveal melanoma cell SP6.5 Western blot BCL2 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM1 Western blot BCL2 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM2 Western blot BCL2 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell KU7 Western blot BCL2 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Downregulation Cancer Sci Hepatocellular carcinoma cell HEPG2 Western blot BCL2 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Downregulation Cancer Sci Hepatocellular carcinoma cell HEP3B Western blot BCL2 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Downregulation Cancer Sci Liver adenocarcinoma cell SK-HEP-1 Western blot BCL2 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Downregulation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot BCL2 19701692 Bone-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Osteosarcoma cell Saos-2 Western blot BCL2 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Leuk Res Myeloma cell RPMI 8226 Western blot BCL2 19489279 Gastric-cancer Homo sapiens Inhibit - - Downregulation Zhonghua Yi Xue Za Zhi Coronary smooth muscle cell HCSMC Western blot BCL2 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/GGT Western blot BCL2 19159621 Leukemia Homo sapiens Inhibit - - Downregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot BCL2 19096576 Brain-cancer Homo sapiens Inhibit Berberine synergy Downregulation J Korean Neurosurg Soc Neuroblastoma cell SH-SY5Y Western blot BCL2 18539383 Lung-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Lung cancer cell CALU-6 Western blot BCL2 18412143 Cervical-cancer Homo sapiens Inhibit - - Downregulation J Cell Physiol Cervical adenocarcinoma cell HeLa Western blot BCL2 18359480 Leukemia Homo sapiens Inhibit Quercetin synergy Upregulation Biochem Pharmacol Histiocytic lymphoma cell U-937 Western blot BCL2 27655700 Liver-cancer Homo sapiens Inhibit Shikonin synergy Downregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot BCL2 27498627 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Rep Chronic myelogenous leukemia cell K-562 Western blot BCL2 27498627 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Rep Acute promyelocytic leukemia cell NB4 Western blot BCL2 27189198 Leukemia Homo sapiens Inhibit Vorinostat synergy Downregulation J Int Med Res Acute promyelocytic leukemia cell NB4 Western blot BCL2 27158419 Lung-cancer Homo sapiens Inhibit - - Downregulation J Cancer Sci Ther Lung adenocarcinoma cell A549 Western blot BCL2 26883975 Prostate-cancer Homo sapiens Inhibit - - Downregulation Life Sci Prostate carcinoma cell LNCaP Western blot BCL2 26883975 Prostate-cancer Homo sapiens Inhibit - - Downregulation Life Sci Prostate carcinoma cell PC-3 Western blot BCL2 26871293 Brain-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Glioma cell U87 Western blot BCL2 26772155 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Downregulation Chem Biol Interact Lung adenocarcinoma cell A549 Western blot BCL2 26622477 Leukemia Homo sapiens Inhibit - - Downregulation Exp Ther Med Acute promyelocytic leukemia cell NB4 Western blot BCL2 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Downregulation Mol Cell Endocrinol Breast cancer cell SK-BR-3 Western blot BCL2 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Downregulation Mol Cell Endocrinol Breast cancer cell MDA-MB-231 Western blot BCL2 17374990 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot BCL2 17300860 Brain-cancer Homo sapiens Inhibit Lipoic-acid detoxicity Upregulation Food Chem Toxicol Glioblastoma cell U118 Western blot BCL2 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Western blot BCL2 16972261 Leukemia Homo sapiens Inhibit U0126 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot BCL2 16972261 Leukemia Homo sapiens Inhibit SP600125 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot BCL2 16867262 Liver-cancer Homo sapiens Inhibit Ascorbic-acid synergy Downregulation Acta Pharmacol Sin Hepatocellular carcinoma cell HEPG2 Western blot BCL2 16818652 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Res Acute promyelocytic leukemia cell NB4 Western blot BCL2 16517539 Brain-cancer Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot BCL2 19771260 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot BCL2 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell MUTZ-1 Western blot BCL2 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell SKM-1 Western blot BCL2 30668372 Neuronal-toxicity Homo sapiens Induce Thymoquinone detoxicity Downregulation Phytomedicine Neuroblastoma cell SH-SY5Y Western blot BCL2 30516227 Kidney-toxicity Gallus gallus Induce - - Downregulation Metallomics - - Western blot BCL2 30343279 Brain-cancer Homo sapiens Inhibit Resveratrol synergy Downregulation Cancer Genomics Proteomics Neuroblastoma cell SKNSH Western blot BCL2 30333888 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Lett Burkitt's lymphoma cell Raji Western blot BCL2 30333888 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Lett Leukemia cell Jurkat Western blot BCL2 16166054 Brain-cancer Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot BCL2 16166054 Brain-cancer Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Neuroblastoma cell SK-N-AS Western blot BCL2 16166054 Leukemia Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Western blot BCL2 16115949 Lymphoma Homo sapiens Inhibit (-)-Epigallocatechin-3-gallate synergy Upregulation Clin Cancer Res Burkitt's lymphoma cell HS-Sultan Western blot BCL2 16105982 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute myeloid leukemia cell ML1 Western blot BCL2 15781666 Leukemia Homo sapiens Inhibit 19-nor-1,25(oh)-2-d-2 synergy Downregulation Cancer Res Acute promyelocytic leukemia cell HL-60 Western blot BCL2 15494640 Bladder-cancer Homo sapiens Inhibit - - Upregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 Western blot BCL2 15493360 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot BCL2 15493360 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot BCL2 15493360 Breast-cancer Homo sapiens Inhibit - - Downregulation Cancer Invest Breast cancer cell MCF7 Western blot BCL2 15291359 Leukemia Homo sapiens Inhibit Phenylarsine-oxide synergy Downregulation Leuk Lymphoma Acute promyelocytic leukemia cell NB4 Western blot BCL2 14703445 Lung-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Jie He He Hu Xi Za Zhi Lung adenocarcinoma cell A549 Western blot BCL2 12975549 Leukemia Homo sapiens Inhibit - - Downregulation Acta Haematol Acute promyelocytic leukemia cell HL-60 Western blot BCL2 12939460 Immune-toxicity Homo sapiens Induce - - Downregulation Mol Cancer Ther Normal peripheral blood cell T cell Western blot BCL2 12883267 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Pancreas Pancreatic cancer cell MIA PaCa-2 Western blot BCL2 12181429 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Mol Pharmacol Large cell lung cancer cell H460 Western blot BCL2 12181429 Breast-cancer Homo sapiens Inhibit - - Phosphorylation Mol Pharmacol Breast cancer cell MCF7 Western blot BCL2 12005185 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell SW480 Western blot BCL2 11834893 Gastric-cancer Homo sapiens Inhibit - - Downregulation Pharmacology Gastric cancer cell MGC-803 Western blot BCL2 11520058 Leukemia Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot BCL2 11027660 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Neuroblastoma cell SK-N-BE(2) Western blot BCL2 11027660 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Neuroblastoma cell IMR-32 Western blot BCL2 11027660 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Neuroblastoma cell SH-SY5Y Western blot BCL2 10942401 Leukemia Homo sapiens Inhibit - - Downregulation Blood Human umbilical vein endothelial cells HUVECs Western blot BCL2 10850458 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Res Myeloma cell MC/CAR Western blot BCL2 9716575 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot BCL2 9716575 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute promyelocytic leukemia cell HL-60 Western blot BCL2 9716575 Leukemia Homo sapiens Inhibit - - Downregulation Blood Histiocytic lymphoma cell U-937 Western blot BCL2 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot BCL2 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot BCL2 26579413 Liver-cancer Homo sapiens Inhibit N-(beta-elemene-13-yl)tryptophan-methyl-ester synergy Upregulation Acta Pharm Sin B Hepatocellular carcinoma cell SMMC-7721 Western blot BCL2 26524030 Lymphoma Homo sapiens Inhibit Adriamycin synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji Western blot BCL2 26494474 Head-and-neck-cancer Homo sapiens Inhibit Dithiothreitol synergy Upregulation Environ Toxicol Oral cancer cell Primarily cultured cell Western blot BCL2 25972196 Liver-cancer Homo sapiens Inhibit - - Upregulation J Toxicol Sci Hepatocellular carcinoma cell HEPG2 Western blot BCL2 25932150 Liver-cancer Homo sapiens Inhibit - - Downregulation Int J Clin Exp Med Hepatocellular carcinoma cell HEPG2 Western blot BCL2 25869069 Leukemia Homo sapiens Inhibit Fludarabine synergy Dephosphorylation Biochem Biophys Res Commun Chronic lymphocytic leukemia cell CLL cell Western blot BCL2 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Downregulation Leuk Lymphoma Acute myelogenous leukemia cell KG-1a Western blot BCL2 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Downregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 Western blot BCL2 25577250 Bone-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot BCL2 25572414 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol lung cancer cell H841 Western blot BCL2 25492486 Liver-cancer Homo sapiens Inhibit Metformin synergy Downregulation Tumour Biol Hepatocellular carcinoma cell HEPG2 Western blot BCL2 25492486 Liver-cancer Homo sapiens Inhibit Metformin synergy Downregulation Tumour Biol Liver cancer cell BEL-7402 Western blot BCL2 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Downregulation Tumour Biol Liver cancer cell Huh7 Western blot BCL2 25338570 Leukemia Homo sapiens Inhibit Curcumin synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot BCL2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot BCL2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot BCL2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot BCL2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot BCL2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot BCL2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot BCL2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC4006 Western blot BCL2 25128771 Bone-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Pharmacol Osteoblasts cell HFOB1.19 Western blot BCL2 24993472 Leukemia Homo sapiens Inhibit - - Downregulation Acta Haematol Chronic myelogenous leukemia cell K-562 Western blot BCL2 24956101 Leukemia Homo sapiens Inhibit - - Downregulation PLoS One Leukemia cell MEC-1 Western blot BCL2 24944602 Leukemia Homo sapiens Inhibit - - Downregulation Exp Ther Med Acute monocytic leukemia cell THP-1 Western blot BCL2 24666483 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot BCL2 24479808 Brain-cancer Homo sapiens Inhibit - - Downregulation Curr Pharm Des Glioma cell U251 Western blot BCL2 24377552 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Asian Pac J Cancer Prev Myeloma cell RPMI 8226 Western blot BCL2 24276018 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Med (Berl) Glioma cell SFxL Western blot BCL2 24276018 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Med (Berl) Glioblastoma cell LN-229 Western blot BCL2 24276018 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Med (Berl) Glioblastoma cell T98G Western blot BCL2 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell SMMC-7721 Western blot BCL2 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell HEPG2 Western blot BCL2 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Downregulation Cancer Biol Ther Kidney cancer cell CAKI-1 Western blot BCL2 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell 143B Western blot BCL2 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell Saos-2 Western blot BCL2 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell U-2 OS Western blot BCL2 23700110 Myeloma Homo sapiens Inhibit Matrine synergy Downregulation Planta Med Myeloma cell RPMI 8226 Western blot BCL2 23700110 Myeloma Homo sapiens Inhibit Matrine synergy Downregulation Planta Med Myeloma cell U266 Western blot Bcl2a1d 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis Bcl2l 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis BCL2L1 19096576 Brain-cancer Homo sapiens Inhibit Berberine synergy Downregulation J Korean Neurosurg Soc Neuroblastoma cell SH-SY5Y Western blot BCL2L1 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Western blot BCL2L1 30343279 Brain-cancer Homo sapiens Inhibit Resveratrol synergy Downregulation Cancer Genomics Proteomics Neuroblastoma cell SKNSH Western blot BCL2L1 15781666 Leukemia Homo sapiens Inhibit 19-nor-1,25(oh)-2-d-2 synergy Downregulation Cancer Res Acute promyelocytic leukemia cell HL-60 Western blot BCL2L1 12939460 Immune-toxicity Homo sapiens Induce - - Downregulation Mol Cancer Ther Normal peripheral blood cell T cell Western blot BCL2L1 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Upregulation Mol Cancer Ther Renal cell adenocarcinoma cell A-498 Western blot BCL2L1 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Downregulation Mol Cancer Ther Renal cell carcinoma cell UOK121N Western blot BCL2L1 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot Bcl2l10 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis BCL2L11 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot BCL2L14 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Bcl2l2 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis BCL7A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BCL9 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis Bclxll 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Downregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR Bclxll 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell RT-PCR Bclxll 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Downregulation Exp Ther Med Leukemia cell WEHI-3 Western blot Bclxll 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Downregulation Cell Physiol Biochem Heart myoblast H9C2 Western blot Bclxll 23201927 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Downregulation Toxicol Lett Heart myoblast H9C2 Western blot Bclxll 18349030 Skin-cancer Mus musculus Inhibit - - Downregulation Ann Oncol Sezary Syndrome cell HuT 78 Western blot Bclxll 18349030 Skin-cancer Mus musculus Inhibit - - Downregulation Ann Oncol Cutaneous t-cell lymphoma cell MyLa 2059 Western blot Bclxll 27561292 Liver-toxicity Rattus norvegicus Induce Allicin detoxicity Downregulation Biol Trace Elem Res - - Western blot Bclxll 23337567 Bone-cancer Rattus norvegicus Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot BCR 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BCR 22330069 Leukemia Homo sapiens Inhibit - - Downregulation Cell Signal Chronic myelogenous leukemia cell K-562 Western blot BCR 22330069 Leukemia Homo sapiens Inhibit - - Downregulation Cell Signal Chronic myelogenous leukemia cell KCL22 Western blot BCR 17121903 Leukemia Homo sapiens Inhibit - - Downregulation Clin Cancer Res Embryonic kidney cell HEK-293 Western blot Bdnf 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR BDNF 16711005 Melanoma Homo sapiens Inhibit - - Downregulation J Huazhong Univ Sci Technolog Med Sci Myeloma cell KM3 Western blot Becn1 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR Becn1 31605998 Development-toxicity Mus musculus Induce NaF detoxicity Upregulation Chemosphere - - QRT-PCR,Western blot Becn1 30225639 Neuronal-toxicity Mus musculus Induce - - Upregulation Arch Toxicol - - QRT-PCR,Western blot Becn1 30225639 Neuronal-toxicity Mus musculus Induce - - Upregulation Arch Toxicol - - QRT-PCR,Western blot Becn1 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot Becn1 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot Becn1 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot Becn1 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot Becn1 32044640 Reproductive-toxicity Mus musculus Induce - - Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 QRT-PCR, Western blot BECN1 17683884 Kidney-toxicity Homo sapiens Induce - - Upregulation Toxicol Lett Epithelial SV40 immortalized uroepithelium cell SV-HUC-1 IHC, Western blot BECN1 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR BECN1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR BECN1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR BECN1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR BECN1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR BECN1 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot BECN1 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot BECN1 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot BECN1 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot BECN1 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot BECN1 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot BECN1 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot BECN1 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell PC-3 QRT-PCR, Western blot BECN1 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell LNCaP QRT-PCR, Western blot BECN1 16882451 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Acute lymphoblastic leukemia cell MOLT-4 QRT-PCR, Western blot BECN1 25110043 Lymphoma Homo sapiens Inhibit - - Upregulation Oncol Rep Burkitt's lymphoma cell Raji QRT-PCR, Western blot BECN1 22519831 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Mech Methods Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot BECN1 22519831 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Mech Methods Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot BECN1 27151017 Myeloma Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell RPMI 8226 RT-PCR, Western blot BECN1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Downregulation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot BECN1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot BECN1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot BECN1 28612524 Liver-cancer Homo sapiens Inhibit - - Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Western blot BECN1 21971985 Leukemia Homo sapiens Inhibit - - Upregulation Int J Mol Med Acute promyelocytic leukemia cell HL-60 Western blot BECN1 21971985 Leukemia Homo sapiens Inhibit - - Upregulation Int J Mol Med Chronic myelogenous leukemia cell K-562 Western blot BECN1 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Upregulation Autophagy Fibrosarcoma cell HT1080 Western blot BECN1 25081691 Lymphoma Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Burkitt's lymphoma cell Raji Western blot betabeta-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis BF1 10673743 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell NB4 RT-PCR Bfar 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis BFAR 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BFL1 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR Bglap 22465848 Bone-toxicity Rattus norvegicus Induce - - Downregulation Bone Primary osteoblast progenitor cell Mature asteoblast QRT-PCR, RT-PCR BGLAP 32954055 Vascular-toxicity Homo sapiens Induce - - Downregulation Bioact Mater Aortic SMC cell VSMCs Western blot BGLF4 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J BurkittĄ¯s lymphoma cell MuTu Western blot BHC80 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Bid 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Upregulation Exp Ther Med Leukemia cell WEHI-3 Western blot Bid 19141569 Liver-toxicity Rattus norvegicus Induce - - Downregulation Toxicol Ind Health Hepatocyte Hepatocytes Western blot BID 28533173 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR BID 21418039 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Int Hepatocellular carcinoma cell SMMC-7721 Western blot BID 19364129 Myeloma Homo sapiens Inhibit - - Upregulation J Proteome Res Myeloma cell U266 Western blot BID 19096576 Brain-cancer Homo sapiens Inhibit Berberine synergy Downregulation J Korean Neurosurg Soc Neuroblastoma cell SH-SY5Y Western blot BID 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Downregulation Blood Myeloma cell RPMI 8226 Western blot BID 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Downregulation Blood Myeloma cell JJN3 Western blot BID 18546268 Leukemia Homo sapiens Inhibit Genistein synergy Downregulation Int J Cancer Histiocytic lymphoma cell U-937 Western blot BID 18359480 Leukemia Homo sapiens Inhibit Quercetin synergy Upregulation Biochem Pharmacol Histiocytic lymphoma cell U-937 Western blot BID 30343279 Brain-cancer Homo sapiens Inhibit Resveratrol synergy Downregulation Cancer Genomics Proteomics Neuroblastoma cell SKNSH Western blot BID 16007134 Leukemia Homo sapiens Inhibit - - Downregulation Oncogene Leukemia cell Jurkat Western blot BID 15735709 Leukemia Homo sapiens Inhibit - - Upregulation Oncogene Multiple myeloma cell IM-9 Western blot BID 11866444 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HLE Western blot BID 11021749 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot BID 24276018 Brain-cancer Homo sapiens Inhibit - - Downregulation J Mol Med (Berl) Glioma cell SFxL Western blot BID 24276018 Brain-cancer Homo sapiens Inhibit - - Downregulation J Mol Med (Berl) Glioblastoma cell LN-229 Western blot BID 24276018 Brain-cancer Homo sapiens Inhibit - - Downregulation J Mol Med (Berl) Glioblastoma cell T98G Western blot Bid3 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis Biklk 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis Bim 22391178 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell KM3 RT-PCR BIM 29574283 Leukemia Homo sapiens Inhibit Vs-5584 synergy Upregulation Biomed Pharmacother Acute lymphoblastic leukemia cell NALM6 QRT-PCR BIM 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell HEPG2 QRT-PCR BIM 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell SMMC-7721 QRT-PCR BIM 21655183 Ovary-cancer Homo sapiens Inhibit Ly294002 synergy Upregulation PLoS One Ovarian cancer cell COC1 Western blot BIM 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Leuk Res Myeloma cell RPMI 8226 Western blot BIM 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Western blot BIM 26540567 Leukemia Homo sapiens Inhibit - - Upregulation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot BIM 26310857 Lymphoma Homo sapiens Inhibit Bortezomib synergy Downregulation Cancer Med Lymphoma cell JeKo-1 Western blot BIM 24956101 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Leukemia cell MEC-1 Western blot Birc1b 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis Birc1e 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis BIRC3 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR Birc4 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis BIRC5 30871073 Brain-cancer Homo sapiens Inhibit (-)-Gossypol synergy Downregulation Cancers (Basel) Glioma stem cell GS-5 QRT-PCR,Western blot BIRC6 30982490 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Res Acute myeloid leukemia cell AML-5 QRT-PCR BIRC6 30982490 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Res Acute promyelocytic leukemia cell HL-60 QRT-PCR BLOC1S4 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot BLOC1S4 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot BMF 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell U266 Western blot BMF 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell RPMI 8226 Western blot BMF 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell MM.1S Western blot BMF 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Multiple myeloma cell KMS-11 Western blot BMI1 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR BMP1 25076250 Esophageal-cancer Homo sapiens Inhibit - - Downregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR BMP1 25076250 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Tumori Colorectal cancer cell LS 174 QRT-PCR BMP4 26215597 Anemia Homo sapiens Inhibit - - Upregulation Acta Biochim Biophys Sin (Shanghai) Mesenchymal stem cells MSCs QRT-PCR,Western blot BMPR2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BMRF1 21605886 Lung-cancer Homo sapiens Inhibit - - Upregulation Virology Nasopharyngeal carcinoma cell CNE1 QRT-PCR BMRF1 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J BurkittĄ¯s lymphoma cell MuTu Western blot BMRF1 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J BurkittĄ¯s lymphoma cell RaeL Western blot BMRF1 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J Peripheral blood mononuclear cell PBMC Western blot BMRF1 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J Lymphoma cell SAV5 Western blot Bnip3 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis BNIP3 15592527 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncogene Glioblastoma cell U-87 MG RT-PCR BNIP3 15592527 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncogene Glioblastoma cell T98G RT-PCR BNIP3 25446377 Lymphoma Homo sapiens Inhibit MG132 synergy Downregulation Eur J Cancer Burkitt's lymphoma cell Raji RT-PCR BNIP3 15592527 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncogene Glioma cell U373MG RT-PCR,Western blot,IHC BNIP3L 15592527 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncogene Glioblastoma cell U-87 MG RT-PCR BNIP3L 15592527 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncogene Glioblastoma cell T98G RT-PCR BNIP3L 15592527 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncogene Glioma cell U373MG RT-PCR,Western blot,IHC BNP 28094846 Heart-toxicity Homo sapiens Induce - - Downregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Kit BOP1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BPI 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BRAF 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR BRAF 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR BRAF 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR BRAF 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR BRCA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BTF3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BTG1 25687055 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot BTG2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis BTK 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR BTK 27733358 Lymphoma Homo sapiens Inhibit - - Phosphorylation Blood Hodgkin lymphoma cell L1236 Western blot BUBR1 19781537 Leukemia Homo sapiens Inhibit Paclitaxel synergy Upregulation,Phosphorylation Chem Biol Interact Leukemia cell Jurkat Western blot BUBR1 19397590 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation Cell Prolif Cervical adenocarcinoma cell HeLa Western blot BUBR1 19371599 Cervical-cancer Homo sapiens Inhibit 17-DMAG synergy Upregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot BUBR1 19371599 Cervical-cancer Homo sapiens Inhibit Knk437 synergy Upregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot BUBR1 18668508 Bladder-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Tumorigenic cell CGL-4 Western blot BUBR1 18668508 Bladder-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Bladder urothelial carcinoma cell BFTC905 Western blot BUBR1 18668508 Bladder-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Bladder transitional carcinoma cell NTUB1 Western blot BUBR1 18668508 Ovary-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Ovarian cancer cell OVCAR-3 Western blot C/EBPBETA 19690170 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot C10ORF3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis C1ORF77 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis C1R 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CA2+-MG2+ATPASE 29274627 Lung-cancer Homo sapiens Inhibit - - Downregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 Kit CA9 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR CABIN1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Cacna1c 23363563 Heart-toxicity Rattus norvegicus Induce Genistein synergy Upregulation Cell Physiol Biochem - - Western blot Cacna1c 23363563 Heart-toxicity Rattus norvegicus Induce Genistein synergy Upregulation Cell Physiol Biochem Neonatal ventricular cell NRVCs Western blot CACNA2D1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CACNB2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CACNG3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CACNG5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CAD 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CALNEXIN 25107562 Heart-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Naunyn Schmiedebergs Arch Pharmacol Embryonic kidney cell HEK-293 Western blot CALPAIN-1 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot CALPAIN-1 27461142 Immune-toxicity Mus musculus Induce - - Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot CALPAIN-1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot CALPAIN-1 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot CALR 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CALR 25107562 Heart-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Naunyn Schmiedebergs Arch Pharmacol Embryonic kidney cell HEK-293 Western blot Camk2 24831965 Neuronal-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR, Western blot Camk2 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Phosphorylation Oncotarget - - Western blot Camk2 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Phosphorylation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot CAMK2G 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CANX 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Capn1 31274337 Vascular-toxicity Mus musculus Induce - - Upregulation Environ Health Perspect - - Western blot CAPN1 31274337 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Health Perspect Human umbilical vein endothelial cells HUVECs Western blot CAPT 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis CAPZA2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CAR 24928535 Ovary-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Ovarian cancer cell OVCAR-3 QRT-PCR CAR 24928535 Ovary-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Ovarian cancer cell CAOV-3 QRT-PCR CASK 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CASKIN2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Casp 16942797 Pheochromocytoma Rattus norvegicus Inhibit - - Upregulation Neurotoxicology Pheochromocytoma cell PC-12 Kit CASP 16579651 Leukemia Homo sapiens Inhibit - - Upregulation Radiat Res Histiocytic lymphoma cell U-937 Kit CASP1 30237538 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Cell Death Dis Hepatocellular carcinoma cell HEPG2 Western blot CASP10 12388546 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Northern blot, Kit CASP10 19771260 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot Casp11 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis casp12 27461142 Immune-toxicity Mus musculus Induce - - Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot Casp12 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis Casp12 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget - - Western blot Casp12 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Casp12 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Casp12 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Molecules Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Casp12 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Molecules - - Western blot Casp12 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Upregulation Toxicol Lett Heart myoblast H9C2 Western blot Casp12 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Upregulation Toxicol Lett Myoblast cell H9c2 Western blot CASP12 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot CASP12 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot CASP12 33174611 Leukemia Homo sapiens Inhibit - - Upregulation Mol Med Rep Acute promyelocytic leukemia cell NB4 R1 Western blot CASP12 33174611 Leukemia Homo sapiens Inhibit - - Upregulation Mol Med Rep Acute promyelocytic leukemia cell NB4 Western blot CASP12 26772155 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Chem Biol Interact Lung adenocarcinoma cell A549 Western blot CASP12 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Upregulation PLoS One Acute promyelocytic leukemia cell NB4 Western blot CASP2 12388546 Leukemia Homo sapiens Inhibit - - Downregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot,Kit casp3 23023949 Genotoxicity Poeciliopsis lucida Induce Selenium detoxicity Upregulation Environ Toxicol Chem Hepatocellular carcinoma cell PLHC-1 Kit casp3 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Environ Pollut - - Western blot Casp3 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Upregulation Biol Trace Elem Res Heart myoblast H9C2 Kit Casp3 23201927 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Toxicol Lett Heart myoblast H9C2 Kit Casp3 18332854 Heart-toxicity Mus musculus Induce Resveratrol detoxicity Upregulation Br J Pharmacol Heart myoblast H9C2 Kit Casp3 28092839 Heart-toxicity Mus musculus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Upregulation Biomed Pharmacother - - Kit Casp3 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Upregulation Biomed Pharmacother Heart myoblast H9C2 Kit Casp3 20079407 Bone-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Lett Bone marrow mononuclear cell BMMCs Kit Casp3 25746422 Heart-toxicity Rattus norvegicus Induce Phloretin detoxicity Upregulation Eur J Pharmacol Heart myoblast H9C2 Kit Casp3 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 Kit, Western blot Casp3 31258454 Development-toxicity Rattus norvegicus Induce - - Upregulation Dose Response - - QRT-PCR Casp3 33352257 Liver-toxicity Mus musculus Induce 3-MA detoxicity Upregulation In Vitro Normal hepatocyte AML12 QRT-PCR, Western blot Casp3 33352257 Liver-toxicity Mus musculus Induce Rapamycin detoxicity Upregulation In Vitro Normal hepatocyte AML12 QRT-PCR, Western blot Casp3 18346055 Heart-toxicity Mus musculus Induce - - Upregulation Basic Clin Pharmacol Toxicol Heart myoblast H9C2 Kit Casp3 23363563 Heart-toxicity Rattus norvegicus Induce Genistein synergy Upregulation Cell Physiol Biochem Neonatal ventricular cell NRVCs Western blot Casp3 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - Western blot Casp3 29095437 Liver-toxicity Mus musculus Induce Metformin detoxicity Upregulation Cell Death Dis Liver cell AML12 Western blot Casp3 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Cell Physiol Biochem Heart myoblast H9C2 Western blot Casp3 22622864 Muscle-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Myoblast cell C2C12 Western blot Casp3 19141569 Liver-toxicity Rattus norvegicus Induce - - Downregulation Toxicol Ind Health Hepatocyte Hepatocytes Western blot Casp3 27748945 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Rep Hepatoma cell HEPA1-6 Western blot Casp3 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Casp3 27461142 Immune-toxicity Mus musculus Induce - - Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot Casp3 15761769 Lymphoma Mus musculus Inhibit - - Upregulation Cancer Chemother Pharmacol B cell lymphoma cell LY-ar Western blot Casp3 15761769 Lymphoma Mus musculus Inhibit - - Upregulation Cancer Chemother Pharmacol B cell lymphoma cell LY-as Western blot Casp3 24801902 Heart-toxicity Mus musculus Induce - - Upregulation Toxicology Atrial cardiomyocyte HL-1 Western blot Casp3 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Upregulation Toxicol Lett Heart myoblast H9C2 Western blot Casp3 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Upregulation Toxicol Lett Myoblast cell H9c2 Western blot Casp3 25268089 Brain-cancer Rattus norvegicus Inhibit - - Upregulation Eur Rev Med Pharmacol Sci Glioma cell C6 Western blot, IHC CASP3 15498110 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 ELISA CASP3 11027660 Brain-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Neuroblastoma cell SK-N-BE(2) ELISA CASP3 11027660 Brain-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Neuroblastoma cell IMR-32 ELISA CASP3 11027660 Brain-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Neuroblastoma cell SH-SY5Y ELISA CASP3 29214213 Liver-cancer Homo sapiens Inhibit - - Upregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Flow cytometry CASP3 28679299 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell Tregs Flow cytometry CASP3 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 Flow cytometry CASP3 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 Flow cytometry CASP3 20796291 Leukemia Homo sapiens Inhibit - - Upregulation J Hematol Oncol Acute promyelocytic leukemia cell HL-60 Flow cytometry CASP3 19208092 Leukemia Homo sapiens Inhibit - - Downregulation Int J Lab Hematol Peripheral blood mononuclear cell Peripheral blood mononuclear Flow cytometry CASP3 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Flow cytometry CASP3 27158419 Lung-cancer Homo sapiens Inhibit - - Upregulation J Cancer Sci Ther Lung adenocarcinoma cell A549 Flow cytometry, Western blot CASP3 15544921 Cervical-cancer Homo sapiens Inhibit - - Upregulation Free Radic Biol Med Esophageal carcinoma cell EC/CUHK1 Kit CASP3 27212442 Pancreas-cancer Homo sapiens Inhibit Px-478 synergy Upregulation Cancer Lett Pancreatic cancer cell PANC-1 IHC CASP3 26887578 Cervical-cancer Homo sapiens Inhibit - - Upregulation Nanoscale Res Lett Cervical carcinoma cell C-33A IHC CASP3 26887578 Cervical-cancer Homo sapiens Inhibit - - Upregulation Nanoscale Res Lett Keratinocyte HK IHC CASP3 26887578 Cervical-cancer Homo sapiens Inhibit - - Upregulation Nanoscale Res Lett Cervical adenocarcinoma cell HeLa IHC CASP3 24908354 Leukemia Homo sapiens Inhibit Deferoxamine synergy Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 IHC, IFA CASP3 15665116 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Kit CASP3 20471514 Leukemia Homo sapiens Inhibit Bortezomib synergy Upregulation Cancer Genet Cytogenet Acute promyelocytic leukemia cell HL-60 Kit CASP3 19465042 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Acute promyelocytic leukemia cell HL-60 Kit CASP3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Kit CASP3 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Kit CASP3 20632473 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Environ Res Public Health Lung adenocarcinoma cell A549 Kit CASP3 20454603 Lung-cancer Homo sapiens Inhibit - - Upregulation Met Ions Biol Med Lung adenocarcinoma cell A549 Kit CASP3 20889596 Rheumatoid-arthritis Homo sapiens Inhibit - - Upregulation J Rheumatol Fibroblast-like synoviocyte fibroblast-like synoviocytes Kit CASP3 17202112 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Acute promyelocytic leukemia cell NB4 Kit CASP3 25128771 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Pharmacol Osteoblasts cell HFOB1.19 Kit CASP3 22245994 Cervical-cancer Homo sapiens Inhibit - - Upregulation Anticancer Drugs Cervical carcinoma cell Ca Ski Kit CASP3 22245994 Cervical-cancer Homo sapiens Inhibit - - Upregulation Anticancer Drugs Cervical adenocarcinoma cell HeLa Kit CASP3 20138156 Leukemia Homo sapiens Inhibit - - Upregulation Int Immunopharmacol Acute monocytic leukemia cell THP-1 Kit CASP3 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-1 Kit CASP3 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-2 Kit CASP3 21787592 Cervical-cancer Homo sapiens Inhibit Humic-acid synergy Upregulation Environ Toxicol Pharmacol Cervical adenocarcinoma cell HeLa Kit CASP3 18633430 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell NB4 Kit CASP3 18633430 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Multiple myeloma cell IM-9 Kit CASP3 18633430 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute lymphoblastic leukemia cell CCRF-CEM Kit CASP3 18633430 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell AR2 Kit CASP3 27592447 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Osteosarcoma cell MG-63 Kit CASP3 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Kit CASP3 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Environ Mol Mutagen Bronchial epithelial cell HBE Kit CASP3 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR CASP3 28459147 Brain-cancer Homo sapiens Inhibit Radiation synergy Upregulation Iran Biomed J Glioblastoma cell U-87 MG QRT-PCR CASP3 27770503 Leukemia Homo sapiens Inhibit - - Upregulation Asia Pac J Clin Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR CASP3 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR CASP3 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR CASP3 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR CASP3 29571380 Liver-toxicity Dicentrarchus labrax Induce - - Upregulation Mar Pollut Bull - - QRT-PCR CASP3 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot CASP3 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot CASP3 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot CASP3 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot CASP3 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot CASP3 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot CASP3 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR,Kit CASP3 32017938 Liver-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Hepatocellular carcinoma cell HEPG2 QRT-PCR, Western blot CASP3 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot CASP3 31718892 Lymphoma Homo sapiens Inhibit - - Upregulation Bioorg Chem Burkitt's lymphoma cell Raji QRT-PCR, Western blot CASP3 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Lymphoma cell Kappas299 QRT-PCR, Western blot CASP3 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot CASP3 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell Jurkat QRT-PCR, Western blot CASP3 22391178 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell KM3 RT-PCR CASP3 27665715 Leukemia Homo sapiens Inhibit Triptolide synergy Upregulation Mol Med Rep Myelodysplastic syndrome cell SKM-1 RT-PCR CASP3 15979894 Leukemia Homo sapiens Inhibit - - Upregulation Pharmacol Res Chronic myelogenous leukemia cell K-562 RT-PCR CASP3 22988968 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Biother Radiopharm Breast cancer cell MCF7 RT-PCR, Western blot CASP3 24738333 Lymphoma Homo sapiens Inhibit Doxorubicin synergy Upregulation J Biomed Nanotechnol Burkitt's lymphoma cell Raji RT-PCR, Western blot CASP3 23660868 Leukemia Homo sapiens Inhibit Vitamin-D3 synergy Upregulation Oncol Rep Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot CASP3 23660868 Leukemia Homo sapiens Inhibit Vitamin-D3 synergy Upregulation Oncol Rep Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot CASP3 23542114 Brain-cancer Homo sapiens Inhibit - - Upregulation Toxicol Lett Glioma cell U251MG Western blot CASP3 23382965 Gastric-cancer Homo sapiens Inhibit - - Upregulation PLoS One Gastric cancer cell FU97 Western blot CASP3 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot CASP3 32952848 Bladder-cancer Homo sapiens Inhibit - - Upregulation Oxid Med Cell Longev Bladder carcinoma cell T24 Western blot CASP3 32290325 Lung-cancer Homo sapiens Inhibit Valproic Acid synergy Upregulation Int J Mol Sci Lung cancer cell NCI-H460 Western blot CASP3 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Hepatocellular carcinoma cell HepG2 Western blot CASP3 31637008 Liver-cancer Homo sapiens Inhibit - - Upregulation Signal Transduct Target Ther Liver cancer cell Huh7 Western blot CASP3 31632492 Leukemia Homo sapiens Inhibit Resveratrol synergy Upregulation J Cancer Chronic myelogenous leukemia cell K-562 Western blot CASP3 31550857 Brain-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Zhong Liu Za Zhi Neuroblastoma cell SKNSH Western blot CASP3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CASP3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot CASP3 29207612 Liver-cancer Homo sapiens Inhibit Andrographolide synergy Upregulation Oncotarget - - Western blot CASP3 29207612 Liver-cancer Homo sapiens Inhibit Andrographolide synergy Downregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot CASP3 29207612 Liver-cancer Homo sapiens Inhibit Andrographolide synergy Upregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot CASP3 29164574 Brain-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Glioma cell U87 Western blot CASP3 31079498 Tongue-cancer Homo sapiens Inhibit - - Upregulation Artif Cells Nanomed Biotechnol Oral squamous cell carcinoma cell Tca-8113 Western blot CASP3 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell MM.1S Western blot CASP3 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell RPMI 8226-S Western blot CASP3 28966729 Colorectal-cancer Homo sapiens Inhibit - - Upregulation J Cancer Sci Ther Colorectal adenocarcinoma cell HT-29 Western blot CASP3 28927142 Lung-cancer Homo sapiens Inhibit - - Upregulation Oncol Lett Lung cancer cell SW 900 Western blot CASP3 28927142 Lung-cancer Homo sapiens Inhibit - - Upregulation Oncol Lett Lung cancer cell SK-MES-1 Western blot CASP3 28823259 Leukemia Homo sapiens Inhibit Itraconazole synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot CASP3 28446277 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot CASP3 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Upregulation J Hematol Oncol Intrahepatic cholangiocarcinoma cell CCLP-1 Western blot CASP3 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Downregulation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot CASP3 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Downregulation J Hematol Oncol Intrahepatic cholangiocarcinoma cell HCCC-9810 Western blot CASP3 23041229 Leukemia Homo sapiens Inhibit 2-deoxy-d-glucose synergy Downregulation Biochem Pharmacol Acute promyelocytic leukemia cell HL-60 Western blot CASP3 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation J Int Med Res Gastric adenocarcinoma cell SGC-7901 Western blot CASP3 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation J Int Med Res Gastric cancer cell MGC-803 Western blot CASP3 22922937 Myeloma Homo sapiens Inhibit Sulforaphane synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot CASP3 22922937 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot CASP3 22922937 Myeloma Homo sapiens Inhibit Erysolin synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot CASP3 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell LNCaP Western blot CASP3 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell PC-3 Western blot CASP3 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Upregulation Int J Oncol Liver cancer cell BEL-7402 Western blot CASP3 21826188 Leukemia Homo sapiens Inhibit Crude-methanolic-extract-of-mucuna-macrocarpa synergy Upregulation Evid Based Complement Alternat Med Acute promyelocytic leukemia cell HL-60 Western blot CASP3 21826188 Leukemia Homo sapiens Inhibit Crude-methanolic-extract-of-mucuna-macrocarpa synergy Upregulation Evid Based Complement Alternat Med Leukemia cell Jurkat Western blot CASP3 21729541 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5R Western blot CASP3 21729541 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5 Western blot CASP3 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioblastoma cell A-172 Western blot CASP3 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Hepatocellular carcinoma cell HEPG2 Western blot CASP3 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Liver cancer cell Huh7 Western blot CASP3 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Sci Epidermoid carcinoma cell A-431 Western blot CASP3 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Sci Keratinocyte HACAT Western blot CASP3 21061466 Melanoma Homo sapiens Inhibit - - Upregulation Am J Chin Med Uveal melanoma cell SP6.5 Western blot CASP3 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Chronic myelogenous leukemia cell K-562 Western blot CASP3 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot CASP3 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell NB4 Western blot CASP3 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell HL-60 Western blot CASP3 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Burkitt's lymphoma cell Raji Western blot CASP3 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Myeloma cell RPMI 8226 Western blot CASP3 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell OPM2 Western blot CASP3 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot CASP3 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Multiple myeloma cell KMS28PE Western blot CASP3 20799280 Mesothelioma Homo sapiens Inhibit - - Upregulation J Cell Physiol Mesothelioma cell NCI-H2052 Western blot CASP3 20724260 Brain-cancer Homo sapiens Inhibit - - Upregulation Can J Neurol Sci Glioma cell U251MG Western blot CASP3 20724260 Brain-cancer Homo sapiens Inhibit - - Upregulation Can J Neurol Sci Glioblastoma cell T98G Western blot CASP3 20723298 Lymphoma Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Mantle cell lymphoma cell MCL Western blot CASP3 19701692 Bone-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Osteosarcoma cell Saos-2 Western blot CASP3 19563028 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell 23DP210 Western blot CASP3 19428345 Leukemia Homo sapiens Inhibit Esculetin synergy Downregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot CASP3 19364129 Myeloma Homo sapiens Inhibit - - Downregulation J Proteome Res Myeloma cell U266 Western blot CASP3 19322013 Bladder-cancer Homo sapiens Inhibit - - Upregulation Urol Int Bladder carcinoma cell T24 Western blot CASP3 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/GGT Western blot CASP3 19159621 Leukemia Homo sapiens Inhibit - - Upregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot CASP3 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-1690 Western blot CASP3 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-1906 Western blot CASP3 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-2020 Western blot CASP3 19096576 Brain-cancer Homo sapiens Inhibit Berberine synergy Downregulation J Korean Neurosurg Soc Neuroblastoma cell SH-SY5Y Western blot CASP3 19060284 Retinoblastoma Homo sapiens Inhibit - - Downregulation Invest Ophthalmol Vis Sci Retinoblastoma cell SNUOT-Rb1 Western blot CASP3 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-1 Western blot CASP3 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell RPMI 8226 Western blot CASP3 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Primary multiple myeloma cell Primary multiple myeloma cell Western blot CASP3 18539383 Lung-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Lung cancer cell CALU-6 Western blot CASP3 18538921 Leukemia Homo sapiens Inhibit ETME synergy Downregulation Cancer Lett Acute promyelocytic leukemia cell HL-60 Western blot CASP3 18538921 Leukemia Homo sapiens Inhibit ETME synergy Downregulation Cancer Lett Acute promyelocytic leukemia cell NB4 Western blot CASP3 18451318 Lung-cancer Homo sapiens Inhibit - - Upregulation J Pharmacol Exp Ther Keratinocyte HACAT Western blot CASP3 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell PC-3 Western blot CASP3 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell LNCaP Western blot CASP3 27665785 Bone-cancer Homo sapiens Inhibit Etoposide synergy Upregulation Int J Oncol Ewing's sarcoma cell A-673 Western blot CASP3 27665785 Bone-cancer Homo sapiens Inhibit Etoposide synergy Upregulation Int J Oncol Neuroblastoma cell SK-N-MC Western blot CASP3 27655700 Liver-cancer Homo sapiens Inhibit Shikonin synergy Downregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot CASP3 27655700 Liver-cancer Homo sapiens Inhibit Shikonin synergy Upregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot CASP3 27430728 Leukemia Homo sapiens Inhibit Curcumin synergy Upregulation Oncol Rep Myelodysplastic syndrome cell SKM-1 Western blot CASP3 27430728 Leukemia Homo sapiens Inhibit Curcumin synergy Upregulation Oncol Rep Acute myelogenous leukemia cell KG-1a Western blot CASP3 27010069 Leukemia Homo sapiens Inhibit - - Upregulation Sci Rep Acute promyelocytic leukemia cell HL-60 Western blot CASP3 27010069 Leukemia Homo sapiens Inhibit - - Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 Western blot CASP3 26987203 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Wei Sheng Yan Jiu Lung adenocarcinoma cell A549 Western blot CASP3 26883975 Prostate-cancer Homo sapiens Inhibit - - Upregulation Life Sci Prostate carcinoma cell LNCaP Western blot CASP3 26883975 Prostate-cancer Homo sapiens Inhibit - - Upregulation Life Sci Prostate carcinoma cell PC-3 Western blot CASP3 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot CASP3 26772155 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Chem Biol Interact Lung adenocarcinoma cell A549 Western blot CASP3 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell RD Western blot CASP3 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell CCA Western blot CASP3 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell RUCH3 Western blot CASP3 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot CASP3 17182041 Leukemia Homo sapiens Inhibit - - Upregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot CASP3 17182041 Leukemia Homo sapiens Inhibit - - Upregulation FEBS Lett Chronic myelogenous leukemia cell KCL22 Western blot CASP3 17145888 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Res Histiocytic lymphoma cell U-937 Western blot CASP3 17145888 Lymphoma Homo sapiens Inhibit - - Downregulation Cancer Res Leukemia cell Jurkat Western blot CASP3 16904648 Gallbladder-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell Western blot CASP3 16867262 Liver-cancer Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Acta Pharmacol Sin Hepatocellular carcinoma cell HEPG2 Western blot CASP3 16569477 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Neuroblastoma cell IMR-32 Western blot CASP3 16517539 Brain-cancer Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot CASP3 19771260 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot CASP3 16434995 Leukemia Homo sapiens Inhibit - - Upregulation Br J Cancer Leukemia cell Jurkat Western blot CASP3 16434995 Leukemia Homo sapiens Inhibit - - Downregulation Br J Cancer Leukemia cell Jurkat Western blot CASP3 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell MUTZ-1 Western blot CASP3 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell SKM-1 Western blot CASP3 30343279 Brain-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Cancer Genomics Proteomics Neuroblastoma cell SKNSH Western blot CASP3 30338810 Leukemia Homo sapiens Inhibit Chloroquine synergy Upregulation Eur Rev Med Pharmacol Sci Acute promyelocytic leukemia cell NB4 Western blot CASP3 30333888 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Lett Burkitt's lymphoma cell Raji Western blot CASP3 30333888 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Lett Leukemia cell Jurkat Western blot CASP3 30213730 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot CASP3 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Lett Chronic myelogenous leukemia cell K-562 Western blot CASP3 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Lett Chronic myelogenous leukemia cell KU812 Western blot CASP3 29774349 Leukemia Homo sapiens Inhibit - - Upregulation Metallomics Acute promyelocytic leukemia cell NB4 Western blot CASP3 16174796 Leukemia Homo sapiens Inhibit - - Downregulation J Pharmacol Exp Ther Blood monocyte BLOOD MONOCYTES Western blot CASP3 16115949 Lymphoma Homo sapiens Inhibit (-)-Epigallocatechin-3-gallate synergy Upregulation Clin Cancer Res Burkitt's lymphoma cell HS-Sultan Western blot CASP3 16051535 Cervical-cancer Homo sapiens Inhibit - - Upregulation J Drug Target Cervical adenocarcinoma cell HeLa Western blot CASP3 16020671 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Neuroblastoma cell SK-N-BE(2)C Western blot CASP3 15735709 Leukemia Homo sapiens Inhibit - - Upregulation Oncogene Multiple myeloma cell IM-9 Western blot CASP3 15604259 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Cervical adenocarcinoma cell HeLa Western blot CASP3 15493360 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot CASP3 15493360 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot CASP3 15493360 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Breast cancer cell MCF7 Western blot CASP3 15178684 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot CASP3 14559676 Lymphoma Homo sapiens Inhibit - - Upregulation Di Yi Jun Yi Da Xue Xue Bao Burkitt's lymphoma cell Raji Western blot CASP3 12760770 Head-and-neck-cancer Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation Zhonghua Kou Qiang Yi Xue Za Zhi Tongue cancer cell OSC-19 Western blot CASP3 12760770 Head-and-neck-cancer Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation Zhonghua Kou Qiang Yi Xue Za Zhi Oral squamous cell carcinoma cell Tca-8113 Western blot CASP3 12754411 Liver-cancer Homo sapiens Inhibit - - Upregulation Exp Mol Med Hepatocellular carcinoma cell HEPG2 Western blot CASP3 12609832 Leukemia Homo sapiens Inhibit Docosahexaenoic-acid synergy Upregulation Blood Acute promyelocytic leukemia cell HL-60 Western blot CASP3 12492118 Myeloma Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Myeloma cell U266 Western blot CASP3 12492118 Myeloma Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Myeloma cell MM.1S Western blot CASP3 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot CASP3 12388546 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot CASP3 12296996 Leukemia Homo sapiens Inhibit - - Upregulation J Biochem Mol Biol Chronic myelogenous leukemia cell K-562 Western blot CASP3 12181429 Lung-cancer Homo sapiens Inhibit - - Downregulation Mol Pharmacol Large cell lung cancer cell H460 Western blot CASP3 12174905 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Anticancer Res Pancreatic cell HPAF Western blot CASP3 12174905 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Anticancer Res Pancreatic cancer cell MIA PaCa-2 Western blot CASP3 12174905 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Anticancer Res Pancreatic cancer cell PANC-1 Western blot CASP3 12168106 Leukemia Homo sapiens Inhibit - - Upregulation Int J Oncol Histiocytic lymphoma cell U-937 Western blot CASP3 26680881 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Treat Acute promyelocytic leukemia cell HL-60 Western blot CASP3 12063550 Cervical-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Cervical adenocarcinoma cell HeLa Western blot CASP3 12034346 Liver-cancer Homo sapiens Inhibit - - Downregulation Life Sci Hepatocellular carcinoma cell HEPG2 Western blot CASP3 12023044 Cervical-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Cervical adenocarcinoma cell HeLa Western blot CASP3 12005185 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell SW480 Western blot CASP3 11866444 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HLE Western blot CASP3 11739184 Lymphoma Homo sapiens Inhibit - - Upregulation Blood T cell leukemia cell MT-2 Western blot CASP3 11520058 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot CASP3 11389037 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Western blot CASP3 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot CASP3 11304686 Leukemia Homo sapiens Inhibit - - Upregulation Int J Cancer Histiocytic lymphoma cell U-937 Western blot CASP3 11172589 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Head and neck cancer cell PCI-1 Western blot CASP3 11146441 Gastric-cancer Homo sapiens Inhibit - - Upregulation Int J Cancer Gastric adenocarcinoma cell AGS Western blot CASP3 11021749 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot CASP3 10850458 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Res Myeloma cell MC/CAR Western blot CASP3 10477740 Leukemia Homo sapiens Inhibit - - Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot CASP3 10428472 Brain-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Neuroblastoma cell SH-SY5Y Western blot CASP3 10328107 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Burkitt's lymphoma cell NAMALWA Western blot CASP3 10328107 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Burkitt's lymphoma cell Raji Western blot CASP3 9864170 Leukemia Homo sapiens Inhibit Ascorbic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot CASP3 26524030 Lymphoma Homo sapiens Inhibit Adriamycin synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji Western blot CASP3 26510911 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma stem cell T387 Western blot CASP3 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell HEPG2 Western blot CASP3 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell SMMC-7721 Western blot CASP3 25932150 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Clin Exp Med Hepatocellular carcinoma cell HEPG2 Western blot CASP3 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Upregulation Leuk Lymphoma Acute myelogenous leukemia cell KG-1a Western blot CASP3 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Upregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 Western blot CASP3 25721870 Leukemia Homo sapiens Inhibit Icariin synergy Upregulation Cell Biochem Biophys Acute promyelocytic leukemia cell HL-60 Western blot CASP3 25721870 Leukemia Homo sapiens Inhibit Icariin synergy Upregulation Cell Biochem Biophys Acute promyelocytic leukemia cell NB4 Western blot CASP3 25721868 Brain-cancer Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Glioma cell U87 Western blot CASP3 25721868 Brain-cancer Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Glioma cell U251 Western blot CASP3 25577250 Bone-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot CASP3 25572414 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol lung cancer cell H841 Western blot CASP3 25506699 Leukemia Homo sapiens Inhibit Etomoxir synergy Upregulation PLoS One Acute promyelocytic leukemia cell HL-60 Western blot CASP3 25499136 Liver-cancer Homo sapiens Inhibit 4-amino-1,8-naphthalimide synergy Upregulation Chem Biol Interact Hepatocellular carcinoma cell HEPG2 Western blot CASP3 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Downregulation Cancer Lett Osteosarcoma cell HOS Western blot CASP3 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Osteosarcoma cell HOS Western blot CASP3 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Downregulation Cancer Lett Fibrosarcoma cell HT1080 Western blot CASP3 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Fibrosarcoma cell HT1080 Western blot CASP3 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Downregulation Tumour Biol Hepatocellular carcinoma cell HEPG2 Western blot CASP3 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Downregulation Tumour Biol Liver cancer cell Huh7 Western blot CASP3 25415199 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Myelodysplastic syndrome cell MUTZ-1 Western blot CASP3 25415199 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Myelodysplastic syndrome cell SKM-1 Western blot CASP3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot CASP3 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot CASP3 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot CASP3 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot CASP3 25115845 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Acute promyelocytic leukemia cell NB4 Western blot CASP3 25110043 Lymphoma Homo sapiens Inhibit - - Upregulation Oncol Rep Burkitt's lymphoma cell Raji Western blot CASP3 24944602 Leukemia Homo sapiens Inhibit - - Upregulation Exp Ther Med Acute monocytic leukemia cell THP-1 Western blot CASP3 24815320 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Western blot CASP3 24482137 Gastric-cancer Homo sapiens Inhibit - - Downregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot CASP3 24482137 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot CASP3 24428916 Leukemia Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation BMC Cancer Acute promyelocytic leukemia cell HL-60 Western blot CASP3 24377552 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Asian Pac J Cancer Prev Myeloma cell RPMI 8226 Western blot CASP3 24356076 Leukemia Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Acute promyelocytic leukemia cell NB4 Western blot CASP3 24356076 Leukemia Homo sapiens Inhibit - - Downregulation Cell Physiol Biochem Acute promyelocytic leukemia cell NB4 Western blot CASP3 24356076 Leukemia Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Acute promyelocytic leukemia cell HL-60 Western blot CASP3 23967052 Bladder-cancer Homo sapiens Inhibit 2-methoxyestradiol synergy Upregulation PLoS One Bladder transitional carcinoma cell NTUB1 Western blot CASP3 23967052 Bladder-cancer Homo sapiens Inhibit 2-methoxyestradiol synergy Upregulation PLoS One Bladder carcinoma cell T24 Western blot CASP3 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Downregulation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 Western blot CASP3 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell 143B Western blot CASP3 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell Saos-2 Western blot CASP3 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell U-2 OS Western blot CASP3 23542114 Brain-cancer Homo sapiens Inhibit - - Upregulation Toxicol Lett Glioblastoma cell U-87 MG Western blot CASP3 12388546 Leukemia Homo sapiens Inhibit - - Downregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot,Kit CASP3 15674346 Leukemia Homo sapiens Inhibit - - - Oncogene Lymphoma cell BJAB Western blot,Kit CASP3 26998898 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation Basic Clin Pharmacol Toxicol Acute promyelocytic leukemia cell NB4 Western blot, IHC CASP4 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioma cell U87 Western blot CASP4 20138156 Leukemia Homo sapiens Inhibit - - Upregulation Int Immunopharmacol Acute monocytic leukemia cell THP-1 Western blot CASP4 19878647 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Polymorphonuclear neutrophils cell Polymorphonuclear neutrophils Western blot CASP4 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot CASP4 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot CASP5 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioma cell U251 Western blot CASP6 25932150 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Clin Exp Med Hepatocellular carcinoma cell HEPG2 Western blot CASP7 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CASP7 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot CASP7 19771260 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot CASP7 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Oncogene Testis carcinoma cell F9 Western blot CASP7 15493360 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot CASP7 15493360 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot CASP7 15493360 Breast-cancer Homo sapiens Inhibit - - Downregulation Cancer Invest Breast cancer cell MCF7 Western blot CASP7 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot CASP7 12181429 Lung-cancer Homo sapiens Inhibit - - Downregulation Mol Pharmacol Large cell lung cancer cell H460 Western blot CASP7 24815320 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Western blot CASP7 23967052 Bladder-cancer Homo sapiens Inhibit 2-methoxyestradiol synergy Upregulation PLoS One Bladder transitional carcinoma cell NTUB1 Western blot CASP7 23967052 Bladder-cancer Homo sapiens Inhibit 2-methoxyestradiol synergy Upregulation PLoS One Bladder carcinoma cell T24 Western blot Casp8 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Upregulation Biomed Pharmacother Heart myoblast H9C2 Western blot CASP8 28679299 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell Tregs Flow cytometry CASP8 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Flow cytometry CASP8 20471514 Leukemia Homo sapiens Inhibit Bortezomib synergy Upregulation Cancer Genet Cytogenet Acute promyelocytic leukemia cell HL-60 Kit CASP8 20889596 Rheumatoid-arthritis Homo sapiens Inhibit - - Upregulation J Rheumatol Fibroblast-like synoviocyte fibroblast-like synoviocytes Kit CASP8 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-1 Kit CASP8 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-2 Kit CASP8 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Environ Mol Mutagen Bronchial epithelial cell HBE Kit CASP8 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR CASP8 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR CASP8 29571380 Liver-toxicity Dicentrarchus labrax Induce - - Upregulation Mar Pollut Bull - - QRT-PCR CASP8 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot CASP8 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot CASP8 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot CASP8 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot CASP8 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Lymphoma cell Kappas299 QRT-PCR, Western blot CASP8 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot CASP8 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell Jurkat QRT-PCR, Western blot CASP8 32290325 Lung-cancer Homo sapiens Inhibit Valproic Acid synergy Upregulation Int J Mol Sci Lung cancer cell NCI-H460 Western blot CASP8 32290325 Lung-cancer Homo sapiens Inhibit Valproic Acid synergy Upregulation Int J Mol Sci Lung cancer cell NCI-H1299 Western blot CASP8 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell MM.1S Western blot CASP8 21729541 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5R Western blot CASP8 21729541 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5 Western blot CASP8 20657188 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot CASP8 20657188 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot CASP8 20138156 Leukemia Homo sapiens Inhibit - - Upregulation Int Immunopharmacol Acute monocytic leukemia cell THP-1 Western blot CASP8 19563028 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell 23DP210 Western blot CASP8 19428345 Leukemia Homo sapiens Inhibit Esculetin synergy Downregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot CASP8 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Downregulation Blood Myeloma cell XG-1 Western blot CASP8 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Downregulation Blood Myeloma cell RPMI 8226 Western blot CASP8 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell JJN3 Western blot CASP8 17182041 Leukemia Homo sapiens Inhibit - - Upregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot CASP8 16972261 Leukemia Homo sapiens Inhibit U0126 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot CASP8 16972261 Leukemia Homo sapiens Inhibit SP600125 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot CASP8 16249384 Leukemia Homo sapiens Inhibit Imatinib-mesylate synergy Upregulation Blood Chronic myelogenous leukemia cell K-562 Western blot CASP8 16174796 Leukemia Homo sapiens Inhibit - - Downregulation J Pharmacol Exp Ther Blood monocyte BLOOD MONOCYTES Western blot CASP8 16007134 Leukemia Homo sapiens Inhibit - - Downregulation Oncogene Leukemia cell Jurkat Western blot CASP8 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell ARP-1 Western blot CASP8 12531793 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell U266 Western blot CASP8 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Burkitt's lymphoma cell HS-Sultan Western blot CASP8 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Multiple myeloma cell IM-9 Western blot CASP8 12388546 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot CASP8 11866444 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HLE Western blot CASP8 11021749 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot CASP8 25415199 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Myelodysplastic syndrome cell MUTZ-1 Western blot CASP8 25415199 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Myelodysplastic syndrome cell SKM-1 Western blot CASP8 25130820 Myeloma Homo sapiens Inhibit Valproic Acid synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell RPMI 8226 Western blot CASP8 24969414 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot CASP8 24377552 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Asian Pac J Cancer Prev Myeloma cell RPMI 8226 Western blot Casp8ap2 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis casp9 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Environ Pollut - - Western blot Casp9 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis Casp9 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Upregulation Exp Ther Med Leukemia cell WEHI-3 Western blot Casp9 22622864 Muscle-toxicity Mus musculus Induce - - Downregulation Arch Toxicol Myoblast cell C2C12 Western blot Casp9 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Upregulation Biomed Pharmacother Heart myoblast H9C2 Western blot Casp9 27748945 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Rep Hepatoma cell HEPA1-6 Western blot Casp9 24801902 Heart-toxicity Mus musculus Induce - - Upregulation Toxicology Atrial cardiomyocyte HL-1 Western blot CASP9 28679299 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell Tregs Flow cytometry CASP9 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Flow cytometry CASP9 15544921 Cervical-cancer Homo sapiens Inhibit - - Upregulation Free Radic Biol Med Esophageal carcinoma cell EC/CUHK1 Kit CASP9 20471514 Leukemia Homo sapiens Inhibit Bortezomib synergy Upregulation Cancer Genet Cytogenet Acute promyelocytic leukemia cell HL-60 Kit CASP9 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Kit CASP9 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Kit CASP9 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-1 Kit CASP9 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-2 Kit CASP9 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Environ Mol Mutagen Bronchial epithelial cell HBE Kit CASP9 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR CASP9 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR CASP9 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR CASP9 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR CASP9 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR CASP9 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR CASP9 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR CASP9 29571380 Liver-toxicity Dicentrarchus labrax Induce - - Upregulation Mar Pollut Bull - - QRT-PCR CASP9 29571380 Gill-toxicity Dicentrarchus labrax Induce - - Upregulation Mar Pollut Bull - - QRT-PCR CASP9 29571380 Immune-toxicity Dicentrarchus labrax Induce - - Upregulation Mar Pollut Bull - - QRT-PCR CASP9 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot CASP9 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot CASP9 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot CASP9 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot CASP9 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Lymphoma cell Kappas299 QRT-PCR, Western blot CASP9 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot CASP9 24103880 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell Jurkat QRT-PCR, Western blot CASP9 25815518 Myeloma Homo sapiens Inhibit Valproic Acid synergy Upregulation Mol Med Rep Myeloma cell RPMI 8226 RT-PCR, Western blot CASP9 25130820 Myeloma Homo sapiens Inhibit Valproic Acid synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell RPMI 8226 RT-PCR, Western blot CASP9 32290325 Lung-cancer Homo sapiens Inhibit Valproic Acid synergy Upregulation Int J Mol Sci Lung cancer cell NCI-H1299 Western blot CASP9 29164574 Brain-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Glioma cell U87 Western blot CASP9 28446277 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot CASP9 23239002 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation Chin J Integr Med Acute promyelocytic leukemia cell HL-60 Western blot CASP9 23041229 Leukemia Homo sapiens Inhibit 2-deoxy-d-glucose synergy Downregulation Biochem Pharmacol Acute promyelocytic leukemia cell HL-60 Western blot CASP9 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation J Int Med Res Gastric adenocarcinoma cell SGC-7901 Western blot CASP9 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation J Int Med Res Gastric cancer cell MGC-803 Western blot CASP9 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Downregulation Int J Oncol Liver cancer cell BEL-7402 Western blot CASP9 21729541 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5R Western blot CASP9 21729541 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5 Western blot CASP9 21061466 Melanoma Homo sapiens Inhibit - - Upregulation Am J Chin Med Uveal melanoma cell SP6.5 Western blot CASP9 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Multiple myeloma cell KMS28PE Western blot CASP9 20723298 Lymphoma Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Mantle cell lymphoma cell MCL Western blot CASP9 20657188 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot CASP9 20657188 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot CASP9 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Hepatocellular carcinoma cell HEPG2 Western blot CASP9 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Hepatocellular carcinoma cell HEP3B Western blot CASP9 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Liver adenocarcinoma cell SK-HEP-1 Western blot CASP9 20138156 Leukemia Homo sapiens Inhibit - - Upregulation Int Immunopharmacol Acute monocytic leukemia cell THP-1 Western blot CASP9 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Upregulation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot CASP9 19701692 Bone-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Osteosarcoma cell Saos-2 Western blot CASP9 19563028 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell 23DP210 Western blot CASP9 19468689 Leukemia Homo sapiens Inhibit - - Upregulation Invest New Drugs Acute promyelocytic leukemia cell HL-60 Western blot CASP9 19428345 Leukemia Homo sapiens Inhibit Esculetin synergy Downregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot CASP9 19371599 Cervical-cancer Homo sapiens Inhibit 17-DMAG synergy Downregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot CASP9 19371599 Cervical-cancer Homo sapiens Inhibit Knk437 synergy Downregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot CASP9 19371599 Cervical-cancer Homo sapiens Inhibit Knk437 synergy Downregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot CASP9 19096576 Brain-cancer Homo sapiens Inhibit Berberine synergy Downregulation J Korean Neurosurg Soc Neuroblastoma cell SH-SY5Y Western blot CASP9 18652763 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation J Int Med Res Acute promyelocytic leukemia cell HL-60 Western blot CASP9 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-1 Western blot CASP9 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell RPMI 8226 Western blot CASP9 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell JJN3 Western blot CASP9 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Primary multiple myeloma cell Primary multiple myeloma cell Western blot CASP9 18387645 Cervical-cancer Homo sapiens Inhibit - - Downregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa Western blot CASP9 18387645 Breast-cancer Homo sapiens Inhibit - - Downregulation Toxicol Appl Pharmacol Breast cancer cell MCF7 Western blot CASP9 17568816 Lymphoma Homo sapiens Inhibit Interferon-alpha synergy Downregulation Leukemia Lymphoma cell BC-3 Western blot CASP9 26629016 Leukemia Homo sapiens Inhibit Hyperoside synergy Upregulation Int J Clin Exp Med Acute promyelocytic leukemia cell HL-60 Western blot CASP9 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot CASP9 17182041 Leukemia Homo sapiens Inhibit - - Upregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot CASP9 16904648 Gallbladder-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell Western blot CASP9 16646077 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Ewing's sarcoma cell EW7 Western blot CASP9 16646077 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Neuroblastoma cell SK-N-MC Western blot CASP9 19771260 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot CASP9 30343279 Brain-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Cancer Genomics Proteomics Neuroblastoma cell SKNSH Western blot CASP9 30213730 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot CASP9 16249384 Leukemia Homo sapiens Inhibit Imatinib-mesylate synergy Upregulation Blood Chronic myelogenous leukemia cell K-562 Western blot CASP9 16007134 Leukemia Homo sapiens Inhibit - - Downregulation Oncogene Leukemia cell Jurkat Western blot CASP9 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Oncogene Testis carcinoma cell F9 Western blot CASP9 15493360 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot CASP9 15493360 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot CASP9 15493360 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Breast cancer cell MCF7 Western blot CASP9 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell ARP-1 Western blot CASP9 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Burkitt's lymphoma cell HS-Sultan Western blot CASP9 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Multiple myeloma cell IM-9 Western blot CASP9 12492118 Myeloma Homo sapiens Inhibit - - Downregulation Mol Cancer Ther Myeloma cell U266 Western blot CASP9 12492118 Myeloma Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Myeloma cell U266 Western blot CASP9 12492118 Myeloma Homo sapiens Inhibit - - Downregulation Mol Cancer Ther Myeloma cell MM.1S Western blot CASP9 12492118 Myeloma Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Myeloma cell MM.1S Western blot CASP9 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot CASP9 26680881 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Treat Acute promyelocytic leukemia cell HL-60 Western blot CASP9 12023044 Cervical-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Cervical adenocarcinoma cell HeLa Western blot CASP9 11866444 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HLE Western blot CASP9 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot CASP9 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot CASP9 11172589 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Head and neck cancer cell PCI-1 Western blot CASP9 26310857 Lymphoma Homo sapiens Inhibit Bortezomib synergy Upregulation Cancer Med Lymphoma cell JeKo-1 Western blot CASP9 25932150 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Clin Exp Med Hepatocellular carcinoma cell HEPG2 Western blot CASP9 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot CASP9 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot CASP9 24815320 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Western blot CASP9 24482137 Gastric-cancer Homo sapiens Inhibit - - Downregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot CASP9 24482137 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot CASP9 24377552 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Asian Pac J Cancer Prev Myeloma cell RPMI 8226 Western blot CASP9 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Upregulation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 Western blot cat 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Cat 28092839 Heart-toxicity Mus musculus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother - - Kit Cat 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother Heart myoblast H9C2 Kit Cat 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR CAT 29214213 Liver-cancer Homo sapiens Inhibit - - Downregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Kit CAT 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - Kit CAT 29467594 Breast-cancer Homo sapiens Inhibit - - Downregulation Cancer Cell Int Breast cancer cell MCF7 QRT-PCR CAT 29467594 Breast-cancer Homo sapiens Inhibit - - Downregulation Cancer Cell Int Breast cancer cell MCF7 QRT-PCR,Western blot CAT 21689642 Breast-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Breast cancer cell MCF7 Western blot CAT 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Downregulation Free Radic Biol Med Melanoma cell C21/GGT Western blot CAT 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/BASAL Western blot CAT 12430174 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Cervical adenocarcinoma cell HeLa Western blot CATB 20302512 Brain-cancer Homo sapiens Inhibit - - Downregulation Biol Chem Glioma cell U87 QRT-PCR, ELISA CATSPER4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CAV1 28521025 Heart-toxicity Homo sapiens Induce - - Downregulation Toxicol Sci Embryonic kidney cell HEK-293 IFA CAV1 17512576 Cervical-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Cervical adenocarcinoma cell HeLa Western blot CAV1 17512576 Cervical-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Cervix squamous cell carcinoma cell SiHa Western blot CBL 19457607 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Lett Acute promyelocytic leukemia cell NB4 Western blot CBL 19457607 Gastric-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Gastric cancer cell MGC-803 Western blot CBL 19457607 Gastric-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Gastric adenocarcinoma cell BGC823 Western blot Cblb 21180886 Leukemia Rattus norvegicus Inhibit Ly294002 synergy Upregulation Braz J Med Biol Res Basophilic leukemia cell RBL-2H3 Western blot CBLB 19457607 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Lett Acute promyelocytic leukemia cell NB4 Western blot CBLB 19457607 Gastric-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Gastric cancer cell MGC-803 Western blot CBR1 22719067 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Histiocytic lymphoma cell U-937 QRT-PCR, Western blot CBR1 22719067 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot CBR1 22719067 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Acute promyelocytic leukemia cell HL-60 Western blot CBR1 22719067 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Acute promyelocytic leukemia cell NB4 Western blot Ccdc39 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR Ccdc40 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR CCDC47 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CCL1 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay Ccl2 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - QRT-PCR CCL2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CCL2 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a QRT-PCR CCL2 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR CCL2 19828696 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Blood Acute promyelocytic leukemia cell NB4 QRT-PCR CCL7 19828696 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Blood Acute promyelocytic leukemia cell NB4 QRT-PCR CCN1 32954055 Vascular-toxicity Homo sapiens Induce - - Upregulation Bioact Mater Primary coronary artery smooth muscle cell PCASMCs QRT-PCR CCNA1 26671917 Lung-cancer Homo sapiens Inhibit - - Upregulation Postepy Hig Med Dosw (Online) Lung adenocarcinoma cell A549 Flow cytometry, QRT-PCR CCNA1 21741957 Leukemia Homo sapiens Inhibit Irradiation synergy Upregulation Chem Biol Interact Acute promyelocytic leukemia cell HL-60 Western blot CCNA1 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM1 Western blot CCNA1 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM2 Western blot CCNA1 19159621 Leukemia Homo sapiens Inhibit - - Upregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot CCNA1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot CCNA1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot CCNA1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot CCNA1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot CCNA1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot CCNA1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot CCNA1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC4006 Western blot CCNA2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ccnb1 26359868 Muscle-toxicity Mus musculus Induce - - Downregulation PLoS One Myoblast cell C2C12 Western blot Ccnb1 23337567 Bone-cancer Rattus norvegicus Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot CCNB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CCNB1 17530438 Brain-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis CCNB1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR CCNB1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR CCNB1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR CCNB1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR CCNB1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR CCNB1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR CCNB1 19825857 Lung-cancer Homo sapiens Inhibit - - Downregulation Toxicol Ind Health Lung adenocarcinoma cell A549 QRT-PCR,Western blot CCNB1 25499136 Liver-cancer Homo sapiens Inhibit 4-amino-1,8-naphthalimide synergy Downregulation Chem Biol Interact Hepatocellular carcinoma cell HEPG2 QRT-PCR, Western blot CCNB1 29059232 Cervical-cancer Homo sapiens Inhibit - - Downregulation PLoS One Cervical adenocarcinoma cell HeLa Western blot CCNB1 29059232 Lymphoma Homo sapiens Inhibit - - Downregulation PLoS One Histiocytic lymphoma cell U-937 Western blot CCNB1 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell MM.1S Western blot CCNB1 21741957 Leukemia Homo sapiens Inhibit Irradiation synergy Upregulation Chem Biol Interact Acute promyelocytic leukemia cell HL-60 Western blot CCNB1 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM1 Western blot CCNB1 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM2 Western blot CCNB1 19159621 Leukemia Homo sapiens Inhibit - - Upregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot CCNB1 18539383 Lung-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Lung cancer cell CALU-6 Western blot CCNB1 26871293 Brain-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Glioma cell U87 Western blot CCNB1 16517539 Brain-cancer Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot CCNB1 16517539 Leukemia Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Western blot CCNB1 12181429 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Pharmacol Breast cancer cell MCF7 Western blot CCNB1 11520058 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot CCNB1 26579413 Liver-cancer Homo sapiens Inhibit N-(beta-elemene-13-yl)tryptophan-methyl-ester synergy Upregulation Acta Pharm Sin B Hepatocellular carcinoma cell SMMC-7721 Western blot CCNB1 25577250 Bone-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot CCNB1 23548265 Lung-cancer Homo sapiens Inhibit Erlotinib synergy Downregulation Mol Cancer Ther Lung adenocarcinoma cell A549 Western blot CCNB1 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot CCNB1 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot CCNB1 12063549 Brain-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Glioblastoma cell U-87 MG Western blot, IFA CCNB1 12063549 Brain-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Glioblastoma cell T98G Western blot, IFA Ccnd1 17617380 Gallbladder-cancer Mus musculus Inhibit - - Downregulation Biochem Biophys Res Commun Gallbladder carcinoma cell Gallbladder carcinoma cell RT-PCR, Western blot Ccnd1 26359868 Muscle-toxicity Mus musculus Induce - - Downregulation PLoS One Myoblast cell C2C12 Western blot CCND1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CCND1 17530438 Brain-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis CCND1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Lymphoma cell JeKo-1 QRT-PCR CCND1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell Mino QRT-PCR CCND1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell SP53 QRT-PCR CCND1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR CCND1 27784375 Myeloma Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell NCI-H929 QRT-PCR CCND1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR CCND1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR CCND1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR CCND1 25945059 Colorectal-cancer Homo sapiens Inhibit Ly294002 synergy Downregulation Onco Targets Ther Colorectal adenocarcinoma cell HT-29 QRT-PCR CCND1 29159499 Leukemia Homo sapiens Inhibit - - Upregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot CCND1 28565807 Leukemia Homo sapiens Inhibit - - Downregulation Exp Ther Med Leukemia cell Jurkat QRT-PCR, Western blot CCND1 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR, Western blot CCND1 20862710 Breast-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Breast epithelial cell MCF 10A QRT-PCR, Western blot CCND1 28245381 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR CCND1 28028657 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot CCND1 25537191 Skin-cancer Homo sapiens Induce - - Upregulation Arch Toxicol Keratinocyte HACAT RT-PCR, Western blot CCND1 29059232 Cervical-cancer Homo sapiens Inhibit - - Downregulation PLoS One Cervical adenocarcinoma cell HeLa Western blot CCND1 29059232 Lymphoma Homo sapiens Inhibit - - Downregulation PLoS One Histiocytic lymphoma cell U-937 Western blot CCND1 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM1 Western blot CCND1 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM2 Western blot CCND1 20723298 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Mantle cell lymphoma cell MCL Western blot CCND1 26883975 Prostate-cancer Homo sapiens Inhibit - - Downregulation Life Sci Prostate carcinoma cell LNCaP Western blot CCND1 26883975 Prostate-cancer Homo sapiens Inhibit - - Downregulation Life Sci Prostate carcinoma cell PC-3 Western blot CCND1 16517539 Leukemia Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Western blot CCND1 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell SCC-4 Western blot CCND1 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell SCC-15 Western blot CCND1 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell CAL 27 Western blot CCND1 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck squamous cell carcinoma cell UM-SCC-47 Western blot CCND1 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck squamous cell carcinoma cell UPCI-SCC-090 Western blot CCND1 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck cancer cell 93-VU-147T Western blot CCND1 10558879 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Head and neck cancer cell PCI-1 Western blot CCND1 26579413 Liver-cancer Homo sapiens Inhibit N-(beta-elemene-13-yl)tryptophan-methyl-ester synergy Upregulation Acta Pharm Sin B Hepatocellular carcinoma cell SMMC-7721 Western blot CCND1 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Downregulation Tumour Biol Liver cancer cell Huh7 Western blot CCND1 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell SMMC-7721 Western blot CCND1 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell HEPG2 Western blot CCND2 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR CCND2 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR CCND2 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR CCND3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CCNE1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR CCNE1 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR CCNE1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR CCNE1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR CCNE1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR CCNE1 29159499 Leukemia Homo sapiens Inhibit - - Upregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot CCNF 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis CCNF 29159499 Leukemia Homo sapiens Inhibit - - Downregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot CCNG2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CCT8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CD11 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 Flow cytometry CD11 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 Flow cytometry CD11 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell Flow cytometry CD13 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40821 Flow cytometry CD13 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR, Flow cytometry CD13 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell HSR-GBM1 QRT-PCR, Western blot, IHC CD133 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR CD133 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97H QRT-PCR CD133 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Large cell lung cancer cell NCI-H460 QRT-PCR, Western blot CD133 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot CD133 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B QRT-PCR, Western blot CD133 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 QRT-PCR, Western blot, Flow cytometry CD133 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioma cell U251MG Western blot CD133 21788103 Gallbladder-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Liver cancer cell Huh7 Western blot CD133 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG Western blot CD133 21788103 Gallbladder-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Gallbladder carcinoma cell Gallbladder carcinoma cell Western blot, IFA CD14 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 Flow cytometry CD14 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 Flow cytometry CD14 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell Flow cytometry CD14 15781666 Leukemia Homo sapiens Inhibit 19-nor-1,25(oh)-2-d-2 synergy Upregulation Cancer Res Acute promyelocytic leukemia cell NB4 Flow cytometry CD14 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR CD147 23232515 Liver-cancer Homo sapiens Inhibit - - Downregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Hepatocellular carcinoma cell SMMC-7721 QRT-PCR, Western blot CD18 18055984 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Haematologica Acute promyelocytic leukemia cell NB4 IFA CD19 27733358 Lymphoma Homo sapiens Inhibit - - Upregulation Blood Hodgkin lymphoma cell L1236 QRT-PCR CD19 27733358 Lymphoma Homo sapiens Inhibit - - Upregulation Blood Hodgkin lymphoma cell L428 QRT-PCR CD20 27733358 Lymphoma Homo sapiens Inhibit - - Upregulation Blood Hodgkin lymphoma cell L1236 QRT-PCR,Western blot CD20 27733358 Lymphoma Homo sapiens Inhibit - - Upregulation Blood Hodgkin lymphoma cell L428 QRT-PCR,Western blot CD22 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Cd31 27671604 Heart-toxicity Rattus norvegicus Induce - - Downregulation Sci Rep - - QRT-PCR,Western blot, IFA CD31 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell SK-OV-3 QRT-PCR CD31 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell A2780 QRT-PCR CD31 27671604 Heart-toxicity Homo sapiens Induce - - Downregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR,Western blot, IFA CD31 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR, IHC CD33 15625759 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell APL Flow cytometry Cd36 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Upregulation Int J Biochem Cell Biol - - Western blot Cd36 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Upregulation Int J Biochem Cell Biol Myoblast cell C2C12 Western blot CD40LG 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay CD44 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR CD44 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97H QRT-PCR CD44V6 22391160 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot CD52 10673743 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell NB4 RT-PCR CD74 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CD86 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CD95 15382040 Cervical-cancer Homo sapiens Inhibit - - Upregulation Int J Cancer Cervical adenocarcinoma cell HeLa RT-PCR, Flow cytometry CD95L 15382040 Cervical-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Cervical adenocarcinoma cell HeLa RT-PCR, Flow cytometry CDC10 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Cdc2 23337567 Bone-cancer Rattus norvegicus Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot CDC2 10558879 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Head and neck cancer cell PCI-1 Northern blot, Western blot CDC2 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling CDC2 19825857 Lung-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Toxicol Ind Health Lung adenocarcinoma cell A549 QRT-PCR,Western blot CDC2 18088464 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR CDC2 22730174 Liver-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation J Cell Biochem Hepatocellular carcinoma cell HEPG2 Western blot CDC2 22730174 Liver-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation J Cell Biochem Hepatocellular carcinoma cell SMMC-7721 Western blot CDC2 21741957 Leukemia Homo sapiens Inhibit Irradiation synergy Upregulation,Phosphorylation Chem Biol Interact Acute promyelocytic leukemia cell HL-60 Western blot CDC2 19159621 Leukemia Homo sapiens Inhibit - - Upregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot CDC2 18539383 Lung-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Lung cancer cell CALU-6 Western blot CDC2 10850458 Myeloma Homo sapiens Inhibit - - Phosphorylation Cancer Res Myeloma cell MC/CAR Western blot CDC2 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot CDC2 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot CDC20 29950208 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot CDC25A 24161621 Brain-cancer Homo sapiens Inhibit U0126 synergy Downregulation Neurochem Int Neuroblastoma cell SK-N-BE(2) QRT-PCR CDC25A 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR, Western blot CDC25B 10850458 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Res Myeloma cell MC/CAR Western blot Cdc25c 23337567 Bone-cancer Rattus norvegicus Inhibit - - Downregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot CDC25C 19781537 Leukemia Homo sapiens Inhibit Paclitaxel synergy Upregulation,Phosphorylation Chem Biol Interact Leukemia cell Jurkat Western blot CDC25C 10850458 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Res Myeloma cell MC/CAR Western blot CDC25C 23337567 Bone-cancer Homo sapiens Inhibit - - Downregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot CDC25C 23337567 Bone-cancer Homo sapiens Inhibit - - Downregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot CDC27 19397590 Cervical-cancer Homo sapiens Inhibit - - Dephosphorylation Cell Prolif Cervical adenocarcinoma cell HeLa Western blot CDC34 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CDC42 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CDC42 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR CDC6 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR, Western blot CDC6 20862710 Breast-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Breast epithelial cell MCF 10A QRT-PCR, Western blot Cdh1 24756364 Liver-cancer Rattus norvegicus Inhibit - - Downregulation J Cancer Res Clin Oncol Hepatoma cell MCA-RH7777 IHC, Western blot CDH1 31003765 Liver-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HCCLM3 QRT-PCR,Western blot CDH1 31003765 Liver-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell SMMC-7721 QRT-PCR,Western blot CDH1 24729530 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Breast cancer cell MDA-MB-231 QRT-PCR, Western blot CDH1 25537191 Skin-cancer Homo sapiens Induce - - Upregulation Arch Toxicol Keratinocyte HACAT RT-PCR, Western blot CDH1 31274337 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Health Perspect Human umbilical vein endothelial cells HUVECs Western blot CDH1 27576314 Bone-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Articular chondrocyte cell HCS-2/8 Western blot CDH1 27576314 Bone-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Chondrosarcoma cell SW 1353 Western blot CDH1 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell 5-8F Western blot CDH1 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell CNE-2 Western blot CDH1 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngealcarcinoma cell 5-8F Western blot CDH1 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngeal carcinoma cell CNE-2 Western blot CDH1 24729530 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Carcinog Breast cancer cell MDA-MB-231 Western blot CDH1 29138840 Liver-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Hepatocellular carcinoma cell HEPG2 Western blot, IHC CDH23 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CDK1 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR CDK1 19781537 Leukemia Homo sapiens Inhibit Paclitaxel synergy Upregulation,Phosphorylation Chem Biol Interact Leukemia cell Jurkat Western blot CDK1 16517539 Brain-cancer Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot CDK1 16517539 Leukemia Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Western blot Cdk2 26359868 Muscle-toxicity Mus musculus Induce - - Downregulation PLoS One Myoblast cell C2C12 Western blot CDK2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CDK2 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR CDK2 30012499 Leukemia Homo sapiens Inhibit Ruxolitinib synergy Downregulation Eur J Pharmacol Histiocytic lymphoma cell U-937 QRT-PCR CDK2 24370028 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell NAMALWA RT-PCR, Western blot CDK2 22331136 Leukemia Homo sapiens Inhibit Tetramethylpyrazine synergy Downregulation Braz J Med Biol Res Acute promyelocytic leukemia cell HL-60 Western blot CDK2 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell SRH Western blot CDK2 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell RD Western blot CDK2 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell RUCH3 Western blot CDK2 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Alveolar hrabdomyosarcomas cell RH-30 Western blot CDK2 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell ZF Western blot CDK2 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot Cdk4 26359868 Muscle-toxicity Mus musculus Induce - - Downregulation PLoS One Myoblast cell C2C12 Western blot CDK4 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis CDK4 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis CDK4 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis CDK4 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Western blot Cdk5 22801079 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi Neurons cell NEURONS QRT-PCR CDK6 10850458 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Res Myeloma cell MC/CAR Northern blot CDK6 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Downregulation Cancers (Basel) Cervical carcinoma cell Ca Ski Western blot CDK6 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Downregulation Cancers (Basel) Cervix squamous cell carcinoma cell SiHa Western blot Cdkn1a 23337567 Bone-cancer Rattus norvegicus Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot CDKN1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CDKN1A 29159499 Leukemia Homo sapiens Inhibit - - Downregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR CDKN1A 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot CDKN1A 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot CDKN1B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CDKN2A 20596618 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Acute lymphoblastic leukemia cell MOLT-4 Western blot CDKN2A 20596618 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Histiocytic lymphoma cell U-937 Western blot CDKN2A 27965050 Leukemia Homo sapiens Inhibit - - Upregulation J Ethnopharmacol Chronic myelogenous leukemia cell K-562 Western blot CDKN2A 27965050 Leukemia Homo sapiens Inhibit - - Upregulation J Ethnopharmacol Chronic myelogenous leukemia cell K-562 Western blot CDKN2B 20596618 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Acute lymphoblastic leukemia cell MOLT-4 Western blot CDKN2B 20596618 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Histiocytic lymphoma cell U-937 Western blot CDKN2D 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CEBPA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CEBPB 15781666 Leukemia Homo sapiens Inhibit 19-nor-1,25(oh)-2-d-2 synergy Upregulation Cancer Res Acute promyelocytic leukemia cell HL-60 Western blot CEBPZ 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CELSR1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CENPC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CEP70 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CETP 27622732 Heart-toxicity Homo sapiens Induce - - Upregulation Chem Biol Interact Hepatocellular carcinoma cell HEPG2 Western blot Cfap43 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR Cfap44 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR, Western blot Cfap69 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR CG8924 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot CGA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CGI12 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CHCHD7 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CHEK1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR CHEK1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR CHFR 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR CHFR 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR CHFR 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR CHGN 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CHIA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Chk1 29097844 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation J Toxicol Pathol - - Western blot CHK1 30871073 Brain-cancer Homo sapiens Inhibit (-)-Gossypol synergy Phosphorylation,Downregulation Cancers (Basel) Glioma stem cell GS-5 QRT-PCR,Western blot CHK1 16891316 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot Chk2 28013460 Skin-toxicity Mus musculus Induce - - Upregulation Environ Sci Pollut Res Int Skin fibroblast m5S Western blot CHK2 30871073 Brain-cancer Homo sapiens Inhibit (-)-Gossypol synergy Downregulation Cancers (Basel) Glioma stem cell GS-5 QRT-PCR,Western blot CHK2 18482988 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot CHK2 18482988 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell HL-60 Western blot CHK2 18482988 Breast-cancer Homo sapiens Inhibit - - Phosphorylation J Biol Chem Breast cancer cell MCF7 Western blot CHK2 16891316 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot CHK2 16891316 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Embryonic kidney cell HEK 293T Western blot CHKA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CHML 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Chop 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Chop 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Chop 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget - - Western blot Chop 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Chop 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Chop 27461142 Immune-toxicity Mus musculus Induce - - Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot Chop 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Molecules Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Chop 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Molecules - - Western blot Chop 23892647 Vascular-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot Chop 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Upregulation Toxicol Lett Heart myoblast H9C2 Western blot Chop 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Upregulation Toxicol Lett Myoblast cell H9c2 Western blot Chop 23494705 Asthma Mus musculus Inhibit - - Upregulation Ir J Med Sci Spleen cell Mouse CD4+ T cell Western blot CHOP 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot CHOP 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell SMMC-7721 QRT-PCR,Western blot CHOP 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioblastoma cell U-87 MG RT-PCR, Western blot CHOP 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CHOP 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot CHOP 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioma cell U251MG Western blot CHOP 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioblastoma cell T98G Western blot CHOP 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioma cell U343 Western blot CHOP 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioma cell U251N Western blot CHOP 27655700 Liver-cancer Homo sapiens Inhibit Shikonin synergy Upregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot CHOP 26772155 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Chem Biol Interact Lung adenocarcinoma cell A549 Western blot CHOP 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell MUTZ-1 Western blot CHOP 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell SKM-1 Western blot CHOP 23880367 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Auris Nasus Larynx Hela carcinoma cell HEP-2 Western blot CHR1 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling CHRNA6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CHST5 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Chuk 28756814 Kidney-toxicity Mus musculus Induce Grape-seed-procyanidin-extract detoxicity Upregulation Biomed Environ Sci - - QRT-PCR,Western blot CHUK 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR CHUK 22384180 Myeloma Homo sapiens Inhibit - - Downregulation PLoS One Myeloma cell NCI-H929 Western blot CIAP2 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR CIAPL 12168106 Leukemia Homo sapiens Inhibit - - Downregulation Int J Oncol Histiocytic lymphoma cell U-937 Western blot CKLFSF6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CKM 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ckmb 19888912 Heart-toxicity Cavia porcellus Induce Vitamin-C detoxicity Upregulation J Environ Pathol Toxicol Oncol - - Kit Clap1 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Downregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR ClAP1 31539632 Breast-cancer Homo sapiens Inhibit BKM120 synergy Downregulation Int J Biochem Cell Biol Breast cancer cell MCF7 QRT-PCR Clap2 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Downregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR Claudin 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR Claudin 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR CLDN11 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - QRT-PCR CLDN15 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - QRT-PCR CLDN3 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - QRT-PCR,Western blot CLDN4 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - QRT-PCR CLDN5 28115242 Gastrointestinal-toxicity Homo sapiens Induce - - Downregulation Toxicology Colorectal adenocarcinoma cell HT-29 Western blot cldn7 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - QRT-PCR CLDN7 28115242 Gastrointestinal-toxicity Homo sapiens Induce - - Downregulation Toxicology Colorectal adenocarcinoma cell HT-29 Western blot CLDN9 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CLK1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CLK3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CLK4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CLN2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CLTA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CLTC 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CMKLR1 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis CNAA 17963750 Posterior-capsule-opacification Homo sapiens Inhibit - - Upregulation Exp Eye Res Lens epithelial cell FHL 124 QRT-PCR CNAA 30913205 Lung-cancer Homo sapiens Inhibit - - Downregulation Med Sci Monit Human umbilical vein endothelial cells HUVECs QRT-PCR, Western blot CNNM2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CNOT6L 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis COFILIN 33174611 Leukemia Homo sapiens Inhibit - - Downregulation Mol Med Rep Acute promyelocytic leukemia cell NB4 R1 QRT-PCR, Western blot COG5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis COL14A1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis COL16A1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Col1A 27671604 Heart-toxicity Rattus norvegicus Induce - - Upregulation Sci Rep - - QRT-PCR COL1A 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR COL1A1 30317545 Skin-toxicity Homo sapiens Induce - - Downregulation J Cell Physiol Primary skin fibroblast Primary skin fibroblast QRT-PCR,Western blot COL1A1 30677399 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Chem Biol Interact Hepatic stellate cell LX-2 Western blot COL1A1 24762191 Pulmonary-fibrosis Homo sapiens Inhibit - - Upregulation Respir Res Normal human lung fibroblast NHLFs Western blot COL1A2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Col3A 27671604 Heart-toxicity Rattus norvegicus Induce - - Upregulation Sci Rep - - QRT-PCR COL3A 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR COL3A1 30317545 Skin-toxicity Homo sapiens Induce - - Downregulation J Cell Physiol Primary skin fibroblast Primary skin fibroblast QRT-PCR,Western blot COL4A1 26469751 Eye-cancer Oryctolagus cuniculus Inhibit - - Downregulation Invest Ophthalmol Vis Sci Primary TenonĄ¯s capsule fibroblast rTFs Western blot COL4A6 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis COL6A3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis COPB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis COVAL 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Cox1 24905690 Immune-toxicity Danio rerio Induce - - Downregulation Ecotoxicol Environ Saf - - QRT-PCR Cox1 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Cox2 31258454 Development-toxicity Rattus norvegicus Induce - - Upregulation Dose Response - - QRT-PCR Cox2 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell PC-3 QRT-PCR COX2 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR COX2 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR COX2 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR COX2 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell LNCaP QRT-PCR COX2 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot COX2 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot COX2 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot COX2 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot COX2 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot COX2 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot COX2 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot COX2 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot COX2 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR, Western blot COX2 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR, Western blot COX2 24312908 Lung-cancer Homo sapiens Inhibit Indomethacin synergy Downregulation Biomed Res Int Lung adenocarcinoma cell A549 RT-PCR, Western blot COX2 21729542 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Western blot COX2 27318970 Liver-cancer Homo sapiens Inhibit - - Downregulation Environ Toxicol Pharmacol Hepatocellular carcinoma cell HEPG2 Western blot COX2 15547942 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 Western blot COX4 27318970 Liver-cancer Homo sapiens Inhibit - - Downregulation Environ Toxicol Pharmacol Hepatocellular carcinoma cell HEPG2 Western blot COX4I1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis COX6C 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis COX7B 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis CP 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CP37 25258189 Bone-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis CPEB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CPOX 23962849 Brain-cancer Homo sapiens Inhibit 5-aminolevulinic-acid synergy Upregulation J Photochem Photobiol B Glioblastoma cell U-87 MG QRT-PCR CPOX 23962849 Brain-cancer Homo sapiens Inhibit 5-aminolevulinic-acid synergy Upregulation J Photochem Photobiol B Glioma cell T98MG QRT-PCR CPP32 16930595 Brain-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Neuroblastoma cell SH-SY5Y Western blot CRBN 28927072 Myeloma Homo sapiens Inhibit Lenalidomide synergy Upregulation Oncol Lett Myeloma cell RPMI 8226 QRT-PCR CRBN 28927072 Myeloma Homo sapiens Inhibit Lenalidomide synergy Upregulation Oncol Lett Myeloma cell U266 QRT-PCR, Western blot CREB 30213730 Leukemia Homo sapiens Inhibit - - Phosphorylation,Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot CREB 24815320 Leukemia Homo sapiens Inhibit - - Phosphorylation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Western blot CREM 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CRI1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CRK 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Phosphorylation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 Western blot CRKL 22339968 Leukemia Homo sapiens Inhibit - - Dephosphorylation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5 Western blot CRKL 22339968 Leukemia Homo sapiens Inhibit - - Dephosphorylation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5R Western blot Crm1 31472347 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - Western blot CRY2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CRYAB 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Csf2 29049341 Immune-toxicity Mus musculus Induce - - Downregulation PLoS One Splenocyte Splenocytes QRT-PCR, ELISA Csf2 22465848 Bone-toxicity Rattus norvegicus Induce - - Downregulation Bone Primary osteoblast progenitor cell Mature asteoblast QRT-PCR, RT-PCR CSF2 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay CSF3 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay CSNK1D 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Csnk2a2 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR CSRC 10448126 Vascular-toxicity Sus scrofa Induce - - Upregulation Toxicol Appl Pharmacol Porcine aortic endothelial cell PAEC Western blot CSRP2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis CSTA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CSTL1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ctgf 29088724 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Oncotarget - - IHC CTGF 29088724 Rheumatoid-arthritis Homo sapiens Inhibit - - Downregulation Oncotarget Rheumatoid arthritis fbroblast-like synoviocyte RAFLS QRT-PCR, ELISA CTNNB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CTNNB1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR CTNNB1 28565807 Leukemia Homo sapiens Inhibit - - Downregulation Exp Ther Med Leukemia cell Jurkat QRT-PCR, Western blot CTNNB1 18485479 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Leuk Res Myeloma cell RPMI 8226 QRT-PCR, Western blot, ELISA CTNNB1 18485479 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Leuk Res Myeloma cell CZ-1 QRT-PCR, Western blot, ELISA CTNNB1 18485479 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Leuk Res Myeloma cell NCI-H929 QRT-PCR, Western blot, ELISA CTNNB1 18485479 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Leuk Res Myeloma cell LP1 QRT-PCR, Western blot, ELISA CTNNB1 18485479 Myeloma Homo sapiens Inhibit Bortezomib synergy Downregulation Leuk Res Myeloma cell U266 QRT-PCR, Western blot, ELISA CTNNB1 28245381 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR CTNNB1 29059232 Lymphoma Homo sapiens Inhibit - - Downregulation PLoS One Histiocytic lymphoma cell U-937 RT-PCR, Western blot CTNNB1 29059232 Cervical-cancer Homo sapiens Inhibit - - Downregulation PLoS One Cervical adenocarcinoma cell HeLa Western blot CTNNB1 28956730 Lung-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Normal lung epithelial cell BEAS-2B Western blot CTNNB1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Lymphoma cell JeKo-1 Western blot CTNNB1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell Mino Western blot CTNNB1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell SP53 Western blot CTNNB1 28789348 Bone-cancer Homo sapiens Inhibit Doxorubicin synergy Downregulation Oncol Lett Osteosarcoma cell MG-63 Western blot CTNNB1 17512576 Cervical-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Cervical adenocarcinoma cell HeLa Western blot CTNNB1 17512576 Cervical-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Cervix squamous cell carcinoma cell SiHa Western blot CTNNB1 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell HL-60 Western blot CTNNB1 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell NB4 Western blot CTNNB1 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell LNCaP Western blot CTNNB1 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell PC-3 Western blot CTNNB1 30213730 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot CTNNB1 25010681 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Colorectal adenocarcinoma cell HT-29 Western blot CTSB 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR,Kit CTSB 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CTSB 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot CTSB 30237538 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Cell Death Dis Hepatocellular carcinoma cell HEPG2 Western blot CTSC 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CTSC 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot Ctsd 23864846 Leukemia Homo sapiens Inhibit PP2 synergy Downregulation Cancer Res Treat Acute promyelocytic leukemia cell NB4 Western blot CTSD 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR CTSE 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CTSE 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot CTSH 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CTSH 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot CTSl 17202112 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Acute promyelocytic leukemia cell NB4 Immunogold labeling CTSS 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot CTSS 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot CUL2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CWF19L1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CXCL11 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay CXCL16 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Cxcr4 28516389 Blood-toxicity Mus musculus Induce - - Downregulation Biol Trace Elem Res Bone marrow cell mouse BM Flow cytometry CXCR4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CXCR4 25047463 Cervical-cancer Homo sapiens Inhibit - - Downregulation Ann Surg Oncol Cervical adenocarcinoma cell HeLa RT-PCR, Western blot CXCR4 25047463 Cervical-cancer Homo sapiens Inhibit - - Downregulation Ann Surg Oncol Cervix squamous cell carcinoma cell SiHa RT-PCR, Western blot CXCR7 30913205 Lung-cancer Homo sapiens Inhibit - - Downregulation Med Sci Monit Human umbilical vein endothelial cells HUVECs QRT-PCR, Western blot CYB5R2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CYBB 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Cyce 26359868 Muscle-toxicity Mus musculus Induce - - Downregulation PLoS One Myoblast cell C2C12 Western blot CYCE 24370028 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell NAMALWA RT-PCR, Western blot CYCE 22331136 Leukemia Homo sapiens Inhibit Tetramethylpyrazine synergy Downregulation Braz J Med Biol Res Acute promyelocytic leukemia cell HL-60 Western blot CYCE 17706770 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Res Acute promyelocytic leukemia cell HL-60 Western blot CYCE 16517539 Brain-cancer Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot CYCE 16517539 Leukemia Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Western blot CYCE 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot Cyp11a 31313246 Development-toxicity Mus musculus Induce - - Downregulation Biol Trace Elem Res Leydig cell Leydig cell QRT-PCR CYP1A1 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis CYP1B1 29876539 Mammary-toxicity Homo sapiens Induce Resveratrol detoxicity Downregulation ACS Omega Breast epithelial cell MCF 10A Western blot CYP26 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Oncogene Testis carcinoma cell F9 RT-PCR CYP3A4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CYP4F11 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis CYR61 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis cytochrome c 23121984 Liver-cancer Poeciliopsis lucida Inhibit - - Upregulation Chemosphere Hepatocellular carcinoma cell PLHC-1 Western blot cytochrome c 15735709 Leukemia Homo sapiens Inhibit - - Upregulation Oncogene Multiple myeloma cell IM-9 Western blot cytochrome C 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Hepatocellular carcinoma cell HEPG2 Western blot cytochrome C 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Hepatocellular carcinoma cell HEP3B Western blot cytochrome C 20219070 Liver-cancer Homo sapiens Inhibit Genistein synergy Upregulation Cancer Sci Liver adenocarcinoma cell SK-HEP-1 Western blot cytochrome C 16132712 Liver-toxicity Rattus norvegicus Induce - - Upregulation Mol Cell Biochem - - Western blot cytochrome C 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot cytochrome C 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot Cytochrome c 15498110 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 ELISA Cytochrome c 29314450 Neuronal-toxicity Homo sapiens Induce Ellagic-acid detoxicity Upregulation J Biochem Mol Toxicol Neuroblastoma cell SH-SY5Y IFA Cytochrome c 15544921 Cervical-cancer Homo sapiens Inhibit - - Upregulation Free Radic Biol Med Esophageal carcinoma cell EC/CUHK1 IFA Cytochrome c 19996132 Liver-cancer Homo sapiens Inhibit - - Upregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling Cytochrome c 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR Cytochrome c 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR Cytochrome c 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR Cytochrome c 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot Cytochrome c 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot Cytochrome c 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot Cytochrome c 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot Cytochrome c 15846091 Liver-toxicity Mus musculus Induce - - Upregulation Cancer Biol Ther Embryonic fibroblast MEFs Western blot Cytochrome c 33174611 Leukemia Homo sapiens Inhibit - - Downregulation Mol Med Rep Acute promyelocytic leukemia cell NB4 R1 Western blot Cytochrome c 29214213 Liver-cancer Homo sapiens Inhibit - - Upregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Western blot Cytochrome c 28966729 Colorectal-cancer Homo sapiens Inhibit - - Downregulation J Cancer Sci Ther Colorectal adenocarcinoma cell HT-29 Western blot Cytochrome c 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Cell Physiol Biochem Heart myoblast H9C2 Western blot Cytochrome c 21061466 Melanoma Homo sapiens Inhibit - - Upregulation Am J Chin Med Uveal melanoma cell SP6.5 Western blot Cytochrome c 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Chronic myelogenous leukemia cell K-562 Western blot Cytochrome c 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot Cytochrome c 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell NB4 Western blot Cytochrome c 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell HL-60 Western blot Cytochrome c 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Burkitt's lymphoma cell Raji Western blot Cytochrome c 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Myeloma cell RPMI 8226 Western blot Cytochrome c 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Upregulation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot Cytochrome c 19342982 Pancreas-cancer Homo sapiens Inhibit Parthenolide synergy Upregulation Pancreas Pancreatic cancer cell PANC-1 Western blot Cytochrome c 19342982 Pancreas-cancer Homo sapiens Inhibit Parthenolide synergy Upregulation Pancreas Pancreatic cancer cell BXPC-3 Western blot Cytochrome c 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/GGT Western blot Cytochrome c 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/BASAL Western blot Cytochrome c 19159621 Leukemia Homo sapiens Inhibit - - Upregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot Cytochrome c 18695917 Cervical-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Cervical adenocarcinoma cell HeLa Western blot Cytochrome c 17690699 Liver-toxicity Mus musculus Induce Trolox detoxicity Downregulation Leukemia Lymphoma cell P388 Western blot Cytochrome c 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Cytochrome c 27158419 Lung-cancer Homo sapiens Inhibit - - Downregulation J Cancer Sci Ther Lung adenocarcinoma cell A549 Western blot Cytochrome c 26987203 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Wei Sheng Yan Jiu Lung adenocarcinoma cell A549 Western blot Cytochrome c 26772155 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Chem Biol Interact Lung adenocarcinoma cell A549 Western blot Cytochrome c 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot Cytochrome c 17202112 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Acute promyelocytic leukemia cell NB4 Western blot Cytochrome c 16972261 Leukemia Homo sapiens Inhibit U0126 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot Cytochrome c 16972261 Leukemia Homo sapiens Inhibit SP600125 synergy Upregulation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot Cytochrome c 16950207 Lung-cancer Homo sapiens Inhibit Sulindac synergy Upregulation Biochem Pharmacol Lung adenocarcinoma cell A549 Western blot Cytochrome c 19771260 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot Cytochrome c 30338810 Leukemia Homo sapiens Inhibit Chloroquine synergy Upregulation Eur Rev Med Pharmacol Sci Acute promyelocytic leukemia cell NB4 Western blot Cytochrome c 16271077 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Sci Glioblastoma cell A-172 Western blot Cytochrome c 16007134 Leukemia Homo sapiens Inhibit - - Upregulation Oncogene Leukemia cell Jurkat Western blot Cytochrome c 15674346 Leukemia Homo sapiens Inhibit - - - Oncogene Lymphoma cell BJAB Western blot Cytochrome c 15665116 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Western blot Cytochrome c 15604259 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Cervical adenocarcinoma cell HeLa Western blot Cytochrome c 12168106 Leukemia Homo sapiens Inhibit - - Upregulation Int J Oncol Histiocytic lymphoma cell U-937 Western blot Cytochrome c 12023044 Cervical-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Cervical adenocarcinoma cell HeLa Western blot Cytochrome c 11866444 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HLE Western blot Cytochrome c 11389037 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Western blot Cytochrome c 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot Cytochrome c 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot Cytochrome c 11304686 Leukemia Homo sapiens Inhibit - - Upregulation Int J Cancer Histiocytic lymphoma cell U-937 Western blot Cytochrome c 11172589 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Head and neck cancer cell PCI-1 Western blot Cytochrome c 25932150 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Clin Exp Med Hepatocellular carcinoma cell HEPG2 Western blot Cytochrome c 25431299 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Biol Trace Elem Res Lung adenocarcinoma cell A549 Western blot Cytochrome c 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Environ Mol Mutagen Bronchial epithelial cell HBE Western blot Cytochrome c 24762191 Pulmonary-fibrosis Homo sapiens Inhibit - - Downregulation Respir Res Normal human lung fibroblast NHLFs Western blot Cytochrome c 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Kidney cancer cell CAKI-1 Western blot Cytochrome c 23737871 Leukemia Homo sapiens Inhibit - - Upregulation Exp Ther Med Chronic myelogenous leukemia cell K-562 Western blot Cytochrome c 20657188 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot, IFA Cytochrome c 20657188 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot, IFA D388N 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR DACH2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DAP5 18491231 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Apoptosis Acute promyelocytic leukemia cell NB4 RT-PCR, Western blot DAPK 17683884 Kidney-toxicity Homo sapiens Induce - - Downregulation Toxicol Lett Epithelial SV40 immortalized uroepithelium cell SV-HUC-1 Western blot DAPK 23898615 Nasopharyngeal-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Nasopharyngeal carcinoma cell CNE-2Z Western blot DAPK1 23898615 Nasopharyngeal-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Nasopharyngeal carcinoma cell CNE-2Z QRT-PCR DAPK2 28978663 Leukemia Homo sapiens Inhibit - - Upregulation J Leukoc Biol Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot DAPK2 28978663 Leukemia Homo sapiens Inhibit - - Upregulation J Leukoc Biol Acute promyelocytic leukemia cell HT93 QRT-PCR, Western blot DAPP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DAXX 19690170 Leukemia Homo sapiens Inhibit - - Downregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot DAZAP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DAZAP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Dbh 23518225 Neuronal-toxicity Mus musculus Induce - - Downregulation Neuroscience - - Western blot DBN1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DBT 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DC2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DCLRE1C 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Dcx 30064059 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Toxicol Pharmacol - - IHC Dcx 26407229 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Toxicol Pharmacol Primary cortical neuron cell Primary rat cortical neuron Western blot DCX 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DDB2 28237621 Lung-toxicity Homo sapiens Induce - - Downregulation DNA Repair (Amst) Lung fibroblast cell IMR-90 QRT-PCR DDIT3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis DDIT3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis DDIT3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DDIT3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis DDX17 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis Ddx25 31472347 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - Western blot DDX26 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ddx3Y 22581830 Reproductive-toxicity Mus musculus Induce - - Downregulation Toxicol Sci - - QRT-PCR, Western blot DEF 12388546 Leukemia Homo sapiens Inhibit - - Downregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot DELTE NP63 ALPHA 23271742 Squamous-cell-carcinoma Homo sapiens Inhibit - - Downregulation J Biol Chem Keratinocyte HACAT Western blot DELTE NP63 ALPHA 23271742 Cervical-cancer Homo sapiens Inhibit - - Downregulation J Biol Chem Cervix epidermoid carcinoma cell ME-180 Western blot DELTE NP63 ALPHA 23271742 Squamous-cell-carcinoma Homo sapiens Inhibit - - Downregulation J Biol Chem Breast epithelial cell MCF 10A Western blot Dffa 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis DGKI 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DHE 27212442 Pancreas-cancer Homo sapiens Inhibit Px-478 synergy Upregulation Cancer Lett Pancreatic cancer cell PANC-1 IHC DIABLO 11389037 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Western blot DIABLO 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Upregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 Western blot DIAPH3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DIPA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DKFZP564D166 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DKK3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DLC1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis DLC1 25534098 Myeloma Homo sapiens Inhibit - - Demethylation Zhonghua Yi Xue Za Zhi Myeloma cell U266 MS,PCR Dll4 31093499 Lung-cancer Homo sapiens Inhibit - - Downregulation Biomed Res Int Small cell lung cancer cell NCI-H69 Western blot DLL4 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung adenocarcinoma cell A549 Western blot DLL4 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Small cell lung cancer cell NCI-H446 Western blot DLL4 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Human umbilical vein endothelial cells HUVECs Western blot DLX3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DNAH7 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DNAJB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DNAJB4 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis DNAJB9 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis DNAJB9 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis DNAJC3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis DNAJC3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis DNASE1L1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Dnmt1 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR Dnmt1 19679824 Breast-cancer Mus musculus Inhibit - - Upregulation Mol Pharmacol Breast cancer cell EMT6 Western blot DNMT1 29159499 Leukemia Homo sapiens Inhibit - - Downregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR DNMT1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR DNMT1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR DNMT1 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR DNMT1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR DNMT1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR DNMT1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR DNMT1 16613325 Liver-cancer Homo sapiens Inhibit - - Downregulation Hum Pathol Hepatocellular carcinoma cell HEPG2 QRT-PCR DNMT1 25534098 Myeloma Homo sapiens Inhibit - - Downregulation Zhonghua Yi Xue Za Zhi Myeloma cell U266 QRT-PCR DNMT1 24819152 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR DNMT1 22558281 Breast-cancer Homo sapiens Inhibit - - Downregulation PLoS One Breast cancer cell MDA-MB-231 RT-PCR DNMT1 20596618 Myeloma Homo sapiens Inhibit - - Downregulation Oncol Rep Myeloma cell U266 RT-PCR DNMT1 17490527 Myeloma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell U266 RT-PCR DNMT1 24993472 Leukemia Homo sapiens Inhibit - - Downregulation Acta Haematol Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot DNMT1 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Hepatocellular carcinoma cell HepG2 Western blot DNMT1 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Liver cancer cell Huh7 Western blot DNMT1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Lymphoma cell JeKo-1 Western blot DNMT1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell Mino Western blot DNMT1 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell SP53 Western blot DNMT1 21687957 Breast-cancer Homo sapiens Inhibit Tamoxifen synergy Downregulation Oncol Rep Ductal carcinoma cell MDA-MB-435S Western blot Dnmt3 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR DNMT3 24819152 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR DNMT3A 29159499 Leukemia Homo sapiens Inhibit - - Downregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR DNMT3A 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR DNMT3A 28218039 Breast-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR DNMT3A 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR DNMT3A 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR DNMT3A 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR DNMT3A 25534098 Myeloma Homo sapiens Inhibit - - Downregulation Zhonghua Yi Xue Za Zhi Myeloma cell U266 QRT-PCR DNMT3A 20596618 Myeloma Homo sapiens Inhibit - - Downregulation Oncol Rep Myeloma cell U266 RT-PCR DNMT3A 20416177 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell CA46 RT-PCR DNMT3A 17490527 Myeloma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell U266 RT-PCR DNMT3A 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Hepatocellular carcinoma cell HepG2 Western blot DNMT3A 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Liver cancer cell Huh7 Western blot Dnmt3b 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR Dnmt3b 19679824 Breast-cancer Mus musculus Inhibit - - Upregulation Mol Pharmacol Breast cancer cell EMT6 Western blot DNMT3B 29159499 Leukemia Homo sapiens Inhibit - - Downregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR DNMT3B 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR DNMT3B 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR DNMT3B 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR DNMT3B 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR DNMT3B 27769816 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR DNMT3B 25534098 Myeloma Homo sapiens Inhibit - - Downregulation Zhonghua Yi Xue Za Zhi Myeloma cell U266 QRT-PCR DNMT3B 24819152 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR DNMT3B 20596618 Myeloma Homo sapiens Inhibit - - Downregulation Oncol Rep Myeloma cell U266 RT-PCR DNMT3B 20416177 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell CA46 RT-PCR DNMT3B 17490527 Myeloma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell U266 RT-PCR DNMT3B 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Hepatocellular carcinoma cell HepG2 Western blot DNMT3B 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Liver cancer cell Huh7 Western blot DOCK3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DOK5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Dpy1912 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR, Western blot DPYSL2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Dr4 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Upregulation Exp Ther Med Leukemia cell WEHI-3 Western blot DR4 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell JJN3 Western blot DR5 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell HEPG2 QRT-PCR DR5 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell SMMC-7721 QRT-PCR DR5 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioblastoma cell U-87 MG RT-PCR, Western blot DR5 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioma cell U251MG Western blot DR5 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioblastoma cell T98G Western blot DR5 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioma cell U343 Western blot DR5 18172319 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Glioma cell U251N Western blot DRE1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Drp1 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR Drp1 29867492 Heart-toxicity Mus musculus Induce Salvianolic-acid-a detoxicity Downregulation Front Pharmacol - - Western blot DRP1 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot DRP1 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot DRP1 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot DRP1 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot DRP1 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot Drp2 27638049 Development-toxicity Mus musculus Induce - - Phosphorylation,Dephosphorylation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot DSCR1 30913205 Lung-cancer Homo sapiens Inhibit - - Upregulation Med Sci Monit Human umbilical vein endothelial cells HUVECs QRT-PCR, Western blot DSG4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DTX2 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 QRT-PCR DTX2 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B QRT-PCR DUOX2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DUSP16 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DUSP2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DUSP5 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis DUSP7 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DUSP8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis DYNEIN 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot DYNEIN 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot DYRK2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis E2F 12679001 Leukemia Homo sapiens Inhibit 8-cpt-camp synergy Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Western blot E2F1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis E2F1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR, Western blot E2F1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR, Western blot E2F1 28927142 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung cancer cell SW 900 Western blot E2F1 28927142 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung cancer cell SK-MES-1 Western blot E2F1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Western blot E2F1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot E2F1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot E2F1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot E2F1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot E2F1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot E2F1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot E2F1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC4006 Western blot E2F1 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H23 Western blot E2F1 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung cancer cell NCI-H358 Western blot E2F1 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H1650 Western blot E2F1 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H1975 Western blot E2F4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis E522K 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR E6 26887578 Cervical-cancer Homo sapiens Inhibit - - Downregulation Nanoscale Res Lett Cervical carcinoma cell C-33A IHC E6 26887578 Cervical-cancer Homo sapiens Inhibit - - Downregulation Nanoscale Res Lett Keratinocyte HK IHC E6 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical adenocarcinoma cell HeLa QRT-PCR,Western blot E6 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervix squamous cell carcinoma cell SiHa QRT-PCR,Western blot E6 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell Ca Ski QRT-PCR,Western blot E6 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell C-33A QRT-PCR,Western blot E6 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell C4-I QRT-PCR,Western blot E6 17374990 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa RT-PCR E6 17374990 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa RT-PCR E6 17374990 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervical carcinoma cell Ca Ski RT-PCR E6 18726487 Cervical-cancer Homo sapiens Inhibit - - Downregulation Sci China C Life Sci Cervical adenocarcinoma cell HeLa RT-PCR, Western blot E6 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck squamous cell carcinoma cell UM-SCC-47 Western blot E6 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck squamous cell carcinoma cell UPCI-SCC-090 Western blot E6 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck cancer cell 93-VU-147T Western blot E7 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical adenocarcinoma cell HeLa QRT-PCR,Western blot E7 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervix squamous cell carcinoma cell SiHa QRT-PCR,Western blot E7 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell Ca Ski QRT-PCR,Western blot E7 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell C-33A QRT-PCR,Western blot E7 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell C4-I QRT-PCR,Western blot E7 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck squamous cell carcinoma cell UM-SCC-47 Western blot E7 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck squamous cell carcinoma cell UPCI-SCC-090 Western blot E7 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Head and neck cancer cell 93-VU-147T Western blot Ecdh1 25123535 Pulmonary-fibrosis Rattus norvegicus Inhibit - - Upregulation Life Sci - - IHC Ecdh1 24756364 Liver-cancer Rattus norvegicus Inhibit - - Upregulation J Cancer Res Clin Oncol Hepatoma cell MCA-RH7777 IHC, Western blot ECDH1 24729530 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Breast cancer cell BT-549 QRT-PCR ECDH1 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR ECDH1 31003765 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HCCLM3 QRT-PCR,Western blot ECDH1 31003765 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell SMMC-7721 QRT-PCR,Western blot ECDH1 16613325 Liver-cancer Homo sapiens Inhibit - - Upregulation Hum Pathol Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot ECDH1 24729530 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Breast cancer cell MDA-MB-231 QRT-PCR, Western blot ECDH1 28956730 Lung-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Normal lung epithelial cell BEAS-2B Western blot ECDH1 17512576 Cervical-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Cervical adenocarcinoma cell HeLa Western blot ECDH1 17512576 Cervical-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Cervix squamous cell carcinoma cell SiHa Western blot ECDH1 27576314 Bone-cancer Homo sapiens Inhibit - - Upregulation J Exp Clin Cancer Res Articular chondrocyte cell HCS-2/8 Western blot ECDH1 27576314 Bone-cancer Homo sapiens Inhibit - - Upregulation J Exp Clin Cancer Res Chondrosarcoma cell SW 1353 Western blot ECDH1 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell 5-8F Western blot ECDH1 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell CNE-2 Western blot ECDH1 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Nasopharyngealcarcinoma cell 5-8F Western blot ECDH1 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Nasopharyngeal carcinoma cell CNE-2 Western blot ECDH1 29409467 Gastric-cancer Homo sapiens Inhibit - - Upregulation BMC Cancer Gastric adenocarcinoma cell AGS Western blot ECDH1 25010681 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Colorectal adenocarcinoma cell HT-29 Western blot ECDH1 24680928 Liver-cancer Homo sapiens Inhibit - - Upregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H Western blot ECM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ECRG4 22325214 Esophageal-cancer Homo sapiens Inhibit - - Downregulation Zhonghua Zhong Liu Za Zhi Esophageal squamous carcinoma cell EC9706 RT-PCR EEF1A1 25258189 Bone-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis EF2 28466809 Leukemia Homo sapiens Inhibit - - Upregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS EFCAB4B 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis EFCBP2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EFNA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EGFl7 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute monocytic leukemia cell THP-1 QRT-PCR EGFl7 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR EGFl7 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR EGFP 24960058 Liver-cancer Homo sapiens Inhibit - - Upregulation Toxicol Lett Hepatocellular carcinoma cell HEPG2 QRT-PCR EGFR 23029451 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation PLoS One Epidermoid carcinoma cell A-431 IHC, Flow cytometry EGFR 30237564 Lung-cancer Homo sapiens Inhibit - - Upregulation Cell Death Dis Lung adenocarcinoma cell A549 Kit, Western blot EGFR 30237564 Lung-cancer Homo sapiens Inhibit - - Upregulation Cell Death Dis Lung adenocarcinoma cell NCI-H1975 Kit, Western blot EGFR 30237564 Lung-cancer Homo sapiens Inhibit - - Upregulation Cell Death Dis Lung adenocarcinoma cell HCC827 Kit, Western blot EGFR 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell KU7 QRT-PCR, Western blot EGFR 23178716 Ovary-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation FEBS Lett Ovarian carcinoma cell HEY Western blot EGFR 22532027 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Epidermoid carcinoma cell A-431 Western blot EGFR 22532027 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Keratinocyte HACAT Western blot EGFR 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell SCC-4 Western blot EGFR 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell SCC-15 Western blot EGFR 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell CAL 27 Western blot EGFR 15961274 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Cell Signal Epidermoid carcinoma cell A-431 Western blot EGFR 25537191 Skin-cancer Homo sapiens Induce - - Phosphorylation Arch Toxicol Keratinocyte HACAT Western blot EGFR 23548265 Lung-cancer Homo sapiens Inhibit Erlotinib synergy Upregulation Mol Cancer Ther Lung adenocarcinoma cell A549 Western blot Egr1 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR EGR1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EGR1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis EGR1 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Oncogene Testis carcinoma cell F9 RT-PCR Eif2a 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Phosphorylation Oncotarget - - Western blot Eif2a 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Phosphorylation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Eif2a 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Phosphorylation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot Eif2a 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Phosphorylation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot EIF2A 23259068 Leukemia Homo sapiens Inhibit - - Phosphorylation Leuk Res Treatment Acute promyelocytic leukemia cell NB4 Western blot EIF2A 23259068 Leukemia Homo sapiens Inhibit - - Phosphorylation Leuk Res Treatment Acute promyelocytic leukemia cell HL-60 Western blot EIF2A 23259068 Leukemia Homo sapiens Inhibit - - Phosphorylation Leuk Res Treatment Histiocytic lymphoma cell U-937 Western blot EIF2A 19878647 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Polymorphonuclear neutrophils cell Polymorphonuclear neutrophils Western blot EIF2A 27655700 Liver-cancer Homo sapiens Inhibit Shikonin synergy Phosphorylation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot EIF2A 25258189 Vascular-toxicity Homo sapiens Induce - - Phosphorylation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot EIF2A 25258189 Bone-toxicity Homo sapiens Induce - - Phosphorylation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot EIF2A 23880367 Head-and-neck-cancer Homo sapiens Inhibit - - Phosphorylation Auris Nasus Larynx Hela carcinoma cell HEP-2 Western blot EIF2A 23880367 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Auris Nasus Larynx Hela carcinoma cell HEP-2 Western blot EIF2AK2 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR EIF2AK3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis EIF2AK3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis EIF3S5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EIF3S8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EIF4E 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EIF4E 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR EIF4E1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Phosphorylation Endocr Relat Cancer Ovarian cancer cell SK-OV-3 Western blot EIF4E1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Phosphorylation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot EIF4E1 29042487 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Mol Cancer Res Glioma cell U87 Western blot EIF4E1 29042487 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Mol Cancer Res Glioblastoma cell LN-229 Western blot EIF4EBP1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR EIF4EBP1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Phosphorylation Endocr Relat Cancer Ovarian cancer cell SK-OV-3 Western blot EIF4EBP1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Phosphorylation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot EIF4EBP1 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Phosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot EIF4EBP1 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Downregulation J Hematol Oncol Intrahepatic cholangiocarcinoma cell HCCC-9810 Western blot EIF4EBP1 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Phosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell HCCC-9810 Western blot EIF4EBP1 22751450 Leukemia Homo sapiens Inhibit - - Dephosphorylation Leukemia Acute promyelocytic leukemia cell NB4 Western blot EIF4EBP1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute myelogenous leukemia cell KG-1 Western blot EIF4EBP1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Leukemia cell MM6 Western blot EIF4EBP1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot EIF4EBP1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Histiocytic lymphoma cell U-937 Western blot EIF4EBP1 17121928 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Leukemia cell KT1 Western blot EIF4EBP1 17121928 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Chronic myelogenous leukemia cell K-562 Western blot EIF4EBP1 17121928 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Chronic myelogenous leukemia cell BV-173 Western blot EIF4EBP1 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Dephosphorylation Tumour Biol Liver cancer cell Huh7 Western blot EIF4G3 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis EIF5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EIF5 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis EIF5A2 30983542 Pancreas-cancer Homo sapiens Inhibit Erlotinib synergy Downregulation J Chemother Pancreatic cancer cell PANC-1 QRT-PCR EIFLAY 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ELAC2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Elf 27638049 Development-toxicity Mus musculus Induce - - Phosphorylation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Elf 23892647 Vascular-toxicity Mus musculus Induce - - Phosphorylation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot Elk1 32683294 Lung-toxicity Mus musculus Induce - - Phosphorylation Toxicol Lett - - Western blot ELK1 32683294 Lung-toxicity Homo sapiens Induce Pd98059 detoxicity Phosphorylation Toxicol Lett Normal lung epithelial cell BEAS-2B Western blot ELKS 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ELMO1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EMD 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis EMP3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ENG 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Eno4 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR ENPP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EP300 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EP300 18822310 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Epidermoid carcinoma cell A-431 Western blot EPCAM 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR EPCAM 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97H QRT-PCR EPHB4 29207612 Liver-cancer Homo sapiens Inhibit Andrographolide synergy Downregulation Oncotarget Hepatocellular carcinoma cell HEPG2 Western blot, IHC, RT-PCR EPHX2 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis EPSTI1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ERALPHA 19088370 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Reprod Sci Endometrial cancer cell Ishikawa QRT-PCR, Western blot ERALPHA 19088370 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Reprod Sci Endometrial carcinoma cell ECC-1 QRT-PCR, Western blot ERBB2IP 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ERBB3 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ERBB4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ERBB4 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis ERG 22889704 Heart-toxicity Cavia porcellus Induce - - Downregulation Int J Cardiol - - Western blot erk1 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Environ Pollut - - Western blot Erk1 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Erk1 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Erk1 23542815 Heart-toxicity Cavia porcellus Induce - - Phosphorylation Toxicol Lett Cardiac fibroblast Cardiac fibroblasts Western blot Erk1 23542815 Heart-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Lett Neonatal cardiac fibroblast NRCF Western blot Erk1 32683294 Lung-toxicity Mus musculus Induce - - Phosphorylation Toxicol Lett - - Western blot Erk1 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Phosphorylation Oncotarget - - Western blot Erk1 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Phosphorylation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Erk1 29111283 Pancreas-toxicity Mus musculus Induce - - Phosphorylation Food Chem Toxicol - - Western blot Erk1 28454374 Skin-cancer Mus musculus Inhibit - - Dephosphorylation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell Western blot Erk1 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Phosphorylation Cell Physiol Biochem Heart myoblast H9C2 Western blot Erk1 22488045 Immune-toxicity Mus musculus Induce - - Phosphorylation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot Erk1 19141569 Liver-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Ind Health Hepatocyte Hepatocytes Western blot Erk1 27638049 Development-toxicity Mus musculus Induce - - Phosphorylation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Erk1 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Phosphorylation Toxicol Lett Heart myoblast H9C2 Western blot ERK1 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Tumour Biol Glioblastoma cell U-87 MG IFA ERK1 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Upregulation Tumour Biol Likely glioblastoma cell U-87 MG IFA ERK1 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Tumour Biol Likely glioblastoma cell U-87 MG IFA ERK1 26459009 Gastric-cancer Homo sapiens Inhibit Doxorubicin synergy Dephosphorylation Mol Med Rep Gastric adenocarcinoma cell SGC-7901 IHC ERK1 17963750 Posterior-capsule-opacification Homo sapiens Inhibit - - Upregulation Exp Eye Res Lens epithelial cell FHL 124 QRT-PCR ERK1 24392034 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation PLoS One Breast adenocarcinoma cell MDA-MB-468 Western blot ERK1 24392034 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation PLoS One Breast cancer cell MCF7 Western blot ERK1 24392034 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation PLoS One Breast cancer cell SK-BR-3 Western blot ERK1 24392034 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation PLoS One Breast epithelial carcinoma cell T-47D Western blot ERK1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Dephosphorylation Endocr Relat Cancer Ovarian cancer cell SK-OV-3 Western blot ERK1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Dephosphorylation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot ERK1 32683294 Lung-toxicity Homo sapiens Induce N-acetylcysteine detoxicity Phosphorylation Toxicol Lett Normal lung epithelial cell BEAS-2B Western blot ERK1 28980872 Breast-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation Cell Cycle Breast cancer cell MCF7 Western blot ERK1 28980872 Breast-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation Cell Cycle Breast cancer cell SK-BR-3 Western blot ERK1 28789348 Bone-cancer Homo sapiens Inhibit Doxorubicin synergy Dephosphorylation Oncol Lett Osteosarcoma cell MG-63 Western blot ERK1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Dephosphorylation Leuk Lymphoma Acute monocytic leukemia cell THP-1 Western blot ERK1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Dephosphorylation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 Western blot ERK1 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Phosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell CCLP-1 Western blot ERK1 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Dephosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot ERK1 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Dephosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell HCCC-9810 Western blot ERK1 23253724 Skin-toxicity Homo sapiens Induce - - Dephosphorylation Chin Med J (Engl) Skin fibroblast HSFB Western blot ERK1 23253724 Skin-toxicity Homo sapiens Induce - - Dephosphorylation Chin Med J (Engl) Acute monocytic leukemia cell THP-1 Western blot ERK1 22751450 Leukemia Homo sapiens Inhibit - - Dephosphorylation Leukemia Acute promyelocytic leukemia cell NB4 Western blot ERK1 22751450 Leukemia Homo sapiens Inhibit - - Dephosphorylation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot ERK1 22532027 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Epidermoid carcinoma cell A-431 Western blot ERK1 22532027 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Keratinocyte HACAT Western blot ERK1 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Phosphorylation Int J Oncol Liver cancer cell BEL-7402 Western blot ERK1 21946058 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Anticancer Drugs Ewing's sarcoma cell A-673 Western blot ERK1 21847655 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation Apoptosis Cervical adenocarcinoma cell HeLa Western blot ERK1 21847655 Breast-cancer Homo sapiens Inhibit - - Phosphorylation Apoptosis Breast cancer cell MCF7 Western blot ERK1 21777978 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Mol Immunol Histiocytic lymphoma cell U-937 Western blot ERK1 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Hepatocellular carcinoma cell HEPG2 Western blot ERK1 21649584 Liver-cancer Homo sapiens Inhibit - - Phosphorylation Biochem J Liver cancer cell Huh7 Western blot ERK1 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Toxicol Sci Epidermoid carcinoma cell A-431 Western blot ERK1 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Toxicol Sci Keratinocyte HACAT Western blot ERK1 20862710 Breast-cancer Homo sapiens Inhibit - - Phosphorylation J Cell Biochem Breast epithelial cell MCF 10A Western blot ERK1 20615082 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Phosphorylation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 Western blot ERK1 20592496 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Biol Ther Osteosarcoma cell HOS Western blot ERK1 20592496 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Biol Ther Osteosarcoma cell MNNG Western blot ERK1 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Upregulation,Phosphorylation Autophagy Fibrosarcoma cell HT1080 Western blot ERK1 20164150 Leukemia Homo sapiens Inhibit - - Upregulation Ann Oncol Leukemia cell Promyelocyte cell Western blot ERK1 19242099 Brain-cancer Homo sapiens Inhibit Irradiation synergy Phosphorylation Autophagy Glioblastoma cell U-118MG Western blot ERK1 19060284 Retinoblastoma Homo sapiens Inhibit - - Phosphorylation Invest Ophthalmol Vis Sci Retinoblastoma cell SNUOT-Rb1 Western blot ERK1 18937079 Liver-cancer Homo sapiens Inhibit Wortmannin synergy Dephosphorylation,Upregulation Med Oncol Hepatocellular carcinoma cell HEPG2 Western blot ERK1 18636201 Lung-cancer Homo sapiens Inhibit Sulindac synergy Phosphorylation Oncol Rep Lung cancer cell NCI-H157 Western blot ERK1 18495609 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Phosphorylation Nan Fang Yi Ke Da Xue Xue Bao Hepatocellular carcinoma cell HEPG2 Western blot ERK1 27794399 Lung-cancer Homo sapiens Inhibit Pd173074 synergy Phosphorylation,Downregulation Lung Cancer Lung cancer cell SK-MES-1 Western blot ERK1 17336041 Cervical-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation Cell Signal Cervical adenocarcinoma cell HeLa Western blot ERK1 17332940 Myeloma Homo sapiens Inhibit - - Dephosphorylation Int J Oncol Multiple myeloma cell IM-9 Western blot ERK1 17332940 Myeloma Homo sapiens Inhibit - - Phosphorylation Int J Oncol Myeloma cell U266 Western blot ERK1 17145888 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Cancer Res Burkitt's lymphoma cell NAMALWA Western blot ERK1 17145888 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Cancer Res Leukemia cell Jurkat Western blot ERK1 16445569 Breast-cancer Homo sapiens Inhibit U0126 synergy Phosphorylation,Downregulation Clin Exp Pharmacol Physiol Breast cancer cell MCF7 Western blot ERK1 16445569 Breast-cancer Homo sapiens Inhibit Pd98059 synergy Phosphorylation,Downregulation Clin Exp Pharmacol Physiol Breast cancer cell MCF7 Western blot ERK1 16360329 Leukemia Homo sapiens Inhibit - - Phosphorylation Blood Cells Mol Dis Chronic myelogenous leukemia cell K-562 Western blot ERK1 16360329 Leukemia Homo sapiens Inhibit - - Phosphorylation Blood Cells Mol Dis Erythroleukemia cell HEL Western blot ERK1 16328441 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Lung adenocarcinoma cell H1355 Western blot ERK1 30467201 Leukemia Homo sapiens Inhibit AC-73 synergy Phosphorylation,Downregulation Haematologica Histiocytic lymphoma cell U-937 Western blot ERK1 30467201 Leukemia Homo sapiens Inhibit AC-73 synergy Phosphorylation,Downregulation Haematologica Acute promyelocytic leukemia cell NB4 Western blot ERK1 30467201 Leukemia Homo sapiens Inhibit AC-73 synergy Phosphorylation,Downregulation Haematologica Biphenotypic B myelomonocytic leukemia cell MV-4-11 Western blot ERK1 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Oncotarget Acute myeloid leukemia cell MOLM14 Western blot ERK1 30213730 Leukemia Homo sapiens Inhibit - - Phosphorylation,Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot ERK1 30014256 Ovary-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation J Biol Inorg Chem Ovarian cancer cell SK-OV-3 Western blot ERK1 30014256 Ovary-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation J Biol Inorg Chem Ovarian cancer cell A2780 Western blot ERK1 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot ERK1 29581752 Liver-cancer Homo sapiens Inhibit Megestrol-acetate synergy Upregulation,Phosphorylation Exp Ther Med Hepatocellular carcinoma cell HEPG2 Western blot ERK1 16283431 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation J Biomed Sci Epidermoid carcinoma cell A-431 Western blot ERK1 15961274 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Cell Signal Epidermoid carcinoma cell A-431 Western blot ERK1 15843040 Leukemia Homo sapiens Inhibit - - Phosphorylation Biochim Biophys Acta Histiocytic lymphoma cell U-937 Western blot ERK1 15781666 Leukemia Homo sapiens Inhibit 19-nor-1,25(oh)-2-d-2 synergy Phosphorylation Cancer Res Acute promyelocytic leukemia cell HL-60 Western blot ERK1 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Testis carcinoma cell F9 Western blot ERK1 15665116 Leukemia Homo sapiens Inhibit - - Phosphorylation Blood Histiocytic lymphoma cell U-937 Western blot ERK1 15580305 Pancreas-cancer Homo sapiens Inhibit - - Dephosphorylation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot ERK1 15580305 Pancreas-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Pancreatic cancer cell BXPC-3 Western blot ERK1 15580305 Pancreas-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Pancreatic cancer cell PANC-1 Western blot ERK1 15538402 Leukemia Homo sapiens Inhibit Pd98059 synergy Phosphorylation Leukemia Acute promyelocytic leukemia cell NB4 Western blot ERK1 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Downregulation Mol Cancer Ther Renal cell adenocarcinoma cell A-498 Western blot ERK1 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Downregulation Mol Cancer Ther Renal cell carcinoma cell UOK121N Western blot ERK1 12754411 Liver-cancer Homo sapiens Inhibit - - Phosphorylation Exp Mol Med Hepatocellular carcinoma cell HEPG2 Western blot ERK1 12296996 Leukemia Homo sapiens Inhibit - - Dephosphorylation J Biochem Mol Biol Chronic myelogenous leukemia cell K-562 Western blot ERK1 11304686 Leukemia Homo sapiens Inhibit - - Downregulation Int J Cancer Histiocytic lymphoma cell U-937 Western blot ERK1 25869069 Leukemia Homo sapiens Inhibit Fludarabine synergy Dephosphorylation Biochem Biophys Res Commun Chronic lymphocytic leukemia cell CLL cell Western blot ERK1 25572414 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Int J Oncol lung cancer cell H841 Western blot ERK1 25506699 Leukemia Homo sapiens Inhibit Etomoxir synergy Phosphorylation PLoS One Acute promyelocytic leukemia cell HL-60 Western blot ERK1 24312908 Lung-cancer Homo sapiens Inhibit Indomethacin synergy Downregulation,Dephosphorylation Biomed Res Int Lung adenocarcinoma cell A549 Western blot ERK1 24273890 Leukemia Homo sapiens Inhibit Vitamin-K2 synergy Downregulation,Dephosphorylation Pharmazie Acute promyelocytic leukemia cell HL-60 Western blot ERK1 24004656 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Pharmacol Res Neuroblastoma cell SH-SY5Y Western blot ERK1 24004656 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Pharmacol Res Neuroblastoma cell IGR-N-91 Western blot Erk5 15761769 Lymphoma Mus musculus Inhibit - - Dephosphorylation Cancer Chemother Pharmacol B cell lymphoma cell LY-ar Western blot Erk5 15761769 Lymphoma Mus musculus Inhibit - - Dephosphorylation Cancer Chemother Pharmacol B cell lymphoma cell LY-as Western blot ERN1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis ERN1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis ESD 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ESR1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ESRA 21687957 Breast-cancer Homo sapiens Inhibit Tamoxifen synergy Downregulation Oncol Rep Ductal carcinoma cell MDA-MB-435S IHC, Western blot ESRA 22558281 Breast-cancer Homo sapiens Inhibit - - Upregulation PLoS One Breast cancer cell MDA-MB-231 RT-PCR, Western blot ESRA 22558281 Breast-cancer Homo sapiens Inhibit - - Upregulation PLoS One Breast cancer cell Hs 578T RT-PCR, Western blot ESRA 15283693 Breast-cancer Homo sapiens Inhibit - - Downregulation J Endocrinol Breast cancer cell MCF7 RT-PCR, Western blot ESRRG 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ESTERASE 17202112 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Acute promyelocytic leukemia cell NB4 Western blot ESX1L 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ETS1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ETS2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ETS2 26274316 Vascular-toxicity Homo sapiens Induce - - Upregulation PLoS One Human umbilical vein endothelial cells HUVECs QRT-PCR,Western blot ETV3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ETV4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis EVA1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis EVI1 20508647 Ovary-cancer Homo sapiens Inhibit - - Downregulation Cell Death Differ Ovarian carcinoma cell HEY QRT-PCR EVI1 24944602 Leukemia Homo sapiens Inhibit - - Downregulation Exp Ther Med Acute monocytic leukemia cell THP-1 RT-PCR, Western blot EZH2 30612216 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Toxicol Breast cancer cell MDA-MB-231 Western blot EZH2 26592252 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute monocytic leukemia cell THP-1 Western blot EZH2 26592252 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell HL-60 Western blot EZH2 26592252 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute myeloid leukemia cell Kasumi-1 Western blot F13A1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis F2Rl1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis F5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FABP3 28094846 Heart-toxicity Homo sapiens Induce - - Downregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Microarray analysis FABP3 28094846 Heart-toxicity Homo sapiens Induce - - Upregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Kit FAF1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis FAHD2A 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis FAK 17336041 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cell Signal Cervical adenocarcinoma cell HeLa Western blot FANCA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FAP 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis FAS 15601551 Lung-cancer Homo sapiens Inhibit - - Upregulation Ai Zheng Lung adenocarcinoma cell SPCA1 Flow cytometry FAS 12478894 Ovary-cancer Homo sapiens Inhibit - - Upregulation Ai Zheng Ovarian cancer cell 3AO Flow cytometry FAS 12452020 Ovary-cancer Homo sapiens Inhibit - - Upregulation Ai Zheng Ovarian cancer cell 3AO Flow cytometry FAS 12126518 Ovary-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Yi Xue Za Zhi Ovarian cancer cell 3AO Flow cytometry FAS 11135700 Liver-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Gan Zang Bing Za Zhi Hepatocarcinoma cell QGY-7701 IHC FAS 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR FAS 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR FAS 29164574 Brain-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Glioma cell U87 QRT-PCR FAS 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR FAS 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR FAS 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot FAS 20819644 Bone-cancer Homo sapiens Inhibit - - Upregulation Chin Med J (Engl) Osteosarcoma cell Saos-2 QRT-PCR, Fas FAS 15979894 Leukemia Homo sapiens Inhibit - - Upregulation Pharmacol Res Chronic myelogenous leukemia cell K-562 RT-PCR FAS 12975549 Leukemia Homo sapiens Inhibit - - Upregulation Acta Haematol Acute promyelocytic leukemia cell HL-60 Western blot FAS 25431299 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Biol Trace Elem Res Lung adenocarcinoma cell A549 Western blot FAS 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Environ Mol Mutagen Bronchial epithelial cell HBE Western blot FAS 24969414 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot FasL 31421153 Vascular-toxicity Homo sapiens Induce - - Upregulation Toxicol Lett Human umbilical vein endothelial cells HUVECs Western blot FASL 29164574 Brain-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Glioma cell U87 QRT-PCR FASL 29574283 Leukemia Homo sapiens Inhibit Vs-5584 synergy Upregulation Biomed Pharmacother Acute lymphoblastic leukemia cell NALM6 QRT-PCR FASL 25431299 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Biol Trace Elem Res Lung adenocarcinoma cell A549 Western blot FASL 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation Environ Mol Mutagen Bronchial epithelial cell HBE Western blot FASLG 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR FBF1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FBXL11 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FBXL4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FBXW7 26592661 Breast-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Breast cancer cell MDA-MB-231 Western blot FBXW7 26592661 Breast-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Breast cancer cell SK-BR-3 Western blot FCGR3A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FERRITIN 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute promyelocytic leukemia cell HL-60 RT-PCR FERRITIN 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute monocytic leukemia cell THP-1 RT-PCR FERRITIN 20950636 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Acute promyelocytic leukemia cell HL-60 Western blot FES 26117010 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR FGF1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 QRT-PCR FGF1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B QRT-PCR FGF2 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung adenocarcinoma cell A549 Western blot FGF2 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Small cell lung cancer cell NCI-H446 Western blot FGF7 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FGFR1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FGFR1 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Human umbilical vein endothelial cells HUVECs Western blot FGFR1 27794399 Lung-cancer Homo sapiens Inhibit Pd173074 synergy Downregulation Lung Cancer Lung cancer cell SK-MES-1 Western blot FGFR1OP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FHOD1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FILIP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FKBP11 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FKBP14 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis FKBP14 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis FKBP1A 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR FLIP 16105982 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute myeloid leukemia cell ML1 QRT-PCR,Western blot FLIP 17673311 Leukemia Homo sapiens Inhibit TNF-alpha synergy Downregulation Biochim Biophys Acta Histiocytic lymphoma cell U-937 Western blot FLIPL 22884570 Leukemia Homo sapiens Inhibit - - Downregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot FLIPL 22884570 Lymphoma Homo sapiens Inhibit - - Downregulation FEBS Lett Leukemia cell Jurkat Western blot FLIPL 22884570 Breast-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Breast cancer cell MCF7 Western blot FLIPL 22884570 Gastric-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Gastric cancer cell MGC-803 Western blot FLIPL 16174796 Leukemia Homo sapiens Inhibit - - Downregulation J Pharmacol Exp Ther Blood monocyte BLOOD MONOCYTES Western blot FLIPL 16174796 Leukemia Homo sapiens Inhibit - - Downregulation J Pharmacol Exp Ther Histiocytic lymphoma cell U-937 Western blot FLIPS 22884570 Leukemia Homo sapiens Inhibit - - Downregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot FLIPS 22884570 Lymphoma Homo sapiens Inhibit - - Downregulation FEBS Lett Leukemia cell Jurkat Western blot FLIPS 22884570 Breast-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Breast cancer cell MCF7 Western blot FLIPS 22884570 Gastric-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Gastric cancer cell MGC-803 Western blot FLIPS 16434995 Leukemia Homo sapiens Inhibit - - Downregulation Br J Cancer Leukemia cell Jurkat Western blot FLJ11235 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FLJ35390 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FLJ40452 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FLJ46672 FIS 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling Flt1 18161919 Gastric-cancer Mus musculus Inhibit - - Downregulation World J Gastroenterol Gastric adenocarcinoma cell SGC-7901 IFA FLT3 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Oncotarget Acute myeloid leukemia cell MOLM14 QRT-PCR, Western blot FLT3 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Oncotarget Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR, Western blot FLT3 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute monocytic leukemia cell THP-1 Western blot FLT3 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 Western blot FLT3 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 Western blot FLT3 17121903 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res - - Western blot FLT3 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot FLT3 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Mol Cancer Ther Megakaryoblastic cell 32D Western blot FLT3 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation,Phosphorylation Mol Cancer Ther Megakaryoblastic cell 32D Western blot FLT3 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Mol Cancer Ther Primary leukemia cell PRIMARY FLT3-ITD AML Western blot FLT3 17121903 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res Erythroleukemia cell HEL Western blot, EMSA FMN2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FN 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR FN1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FN1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis FN1 26469751 Eye-cancer Oryctolagus cuniculus Inhibit - - Downregulation Invest Ophthalmol Vis Sci Primary TenonĄ¯s capsule fibroblast rTFs Western blot FNBP4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FOLR2 28686804 Leukemia Homo sapiens Inhibit - - Upregulation Angew Chem Int Ed Engl Chronic myelogenous leukemia cell K-562 Western blot Fos 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR FOS 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FOS 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis FOS 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR FOS 25076250 Esophageal-cancer Homo sapiens Inhibit - - Upregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR FOS 18822310 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Epidermoid carcinoma cell A-431 RT-PCR, Western blot FOS 24956101 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Chronic lymphocytic leukemia cell CLL cell RT-PCR, Western blot FOS 28446277 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot FOS 22719067 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Cancer Res Histiocytic lymphoma cell U-937 Western blot FOS 27158419 Lung-cancer Homo sapiens Inhibit - - Downregulation J Cancer Sci Ther Lung adenocarcinoma cell A549 Western blot FOS 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Downregulation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 Western blot FOXM1 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR, Western blot FOXM1 25485499 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Pancreatic cancer cell MIA PaCa-2 Western blot FOXM1 25485499 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Prostate carcinoma cell DU 145 Western blot FOXM1 25485499 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Osteosarcoma cell U-2 OS Western blot FoxO1 32184170 Muscle-toxicity Mus musculus Induce - - Upregulation Toxicol In Vitro Myoblast cell C2C12 Western blot FOXO1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR FoxO3a 31421153 Vascular-toxicity Homo sapiens Induce - - Upregulation Toxicol Lett Human umbilical vein endothelial cells HUVECs Western blot FOXO3a 31539632 Breast-cancer Homo sapiens Inhibit BKM120 synergy Upregulation Int J Biochem Cell Biol Breast cancer cell MCF7 QRT-PCR FOXO3A 30477221 Gastric-cancer Homo sapiens Inhibit - - Upregulation Int J Mol Sci Gastric cancer cell MGC-803 IFA, Western blot FOXO3A 30477221 Gastric-cancer Homo sapiens Inhibit - - Upregulation Int J Mol Sci Gastric adenocarcinoma cell SGC-7901 IFA, Western blot FOXO3A 22988968 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Biother Radiopharm Breast cancer cell MCF7 RT-PCR, Western blot FOXO3A 18937079 Liver-cancer Homo sapiens Inhibit Wortmannin synergy Dephosphorylation,Upregulation Med Oncol Hepatocellular carcinoma cell HEPG2 Western blot FOXO3A 27010069 Leukemia Homo sapiens Inhibit - - Upregulation Sci Rep Acute promyelocytic leukemia cell HL-60 Western blot FOXO3A 27010069 Leukemia Homo sapiens Inhibit - - Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 Western blot Foxp3 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol - - IFA Foxp3 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol - - IFA Foxp3 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol CD4+T cell CD4+T cell QRT-PCR Foxp3 27677289 Colorectal-cancer Mus musculus Inhibit - - Downregulation Tumour Biol Cytokine induced killer cell Cytokine induced killer cell RT-PCR FOXP3 31871961 Rheumatoid-arthritis Homo sapiens Inhibit - - Upregulation Data Brief T cell Tregs QRT-PCR FOXP3 29552182 Immune-toxicity Homo sapiens Induce - - Downregulation Oncol Lett Ascites-derived tumor-infiltrating lymphocyte TILs QRT-PCR FOXP3 23802174 Immune-toxicity Homo sapiens Induce - - Downregulation Immunol Invest Lymphocyte cell ALLOREACTIVE CD4+ MEMORY T CELL QRT-PCR FOXP3 30213730 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot FRAP1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR FSCN1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Fsp1 27671604 Heart-toxicity Rattus norvegicus Induce - - Upregulation Sci Rep - - QRT-PCR,Western blot FSP1 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR,Western blot FTH1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FTL 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FTMT 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FUCA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FUT4 15755292 Leukemia Homo sapiens Inhibit - - Upregulation Br J Haematol Acute promyelocytic leukemia cell NB4 Flow cytometry FUT6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FUT7 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FX 21272920 Hematologic-toxicity Homo sapiens Induce - - Upregulation Thromb Res Human umbilical vein endothelial cells HUVECs Kit FXA 21272920 Hematologic-toxicity Homo sapiens Induce - - Upregulation Thromb Res Human umbilical vein endothelial cells HUVECs Kit FY 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis FZD1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis G457S 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR G6PC3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GA17 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GABAAR 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis GABARAPL1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR GABARAPL1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR GABARAPl2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GABARAPl2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR GABARAPl2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR GABRA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GADD153 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot GADD153 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot GADD153 19878647 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Polymorphonuclear neutrophils cell Polymorphonuclear neutrophils RT-PCR GADD153 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Western blot GADD153 15493360 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot GADD153 15493360 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot GADD153 15493360 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Breast cancer cell MCF7 Western blot GADD153 12883267 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Pancreas Pancreatic cancer cell MIA PaCa-2 Western blot GADD153 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot GADD153 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot Gadd45 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR Gadd45a 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis GADD45A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GADD45A 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis GADD45A 17530438 Brain-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis GADD45A 29159499 Leukemia Homo sapiens Inhibit - - Upregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR GADD45A 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR GADD45A 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR GADD45A 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR GADD45A 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR GADD45A 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR GADD45A 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR GADD45A 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot GADD45A 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot GADD45A 15493360 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot GADD45A 15493360 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot GADD45A 15493360 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Breast cancer cell MCF7 Western blot GADD45A 12883267 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Pancreas Pancreatic cancer cell MIA PaCa-2 Western blot GADD45B 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GADD45B 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Liver cancer cell Huh7.5.1 QRT-PCR GADD45B 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR GAGED2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GAK 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GAL 16968895 Leukemia Homo sapiens Inhibit - - Downregulation Blood Hepatocellular carcinoma cell HEP3B ELISA GAL3 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Kidney cancer cell CAKI-1 IHC, Western blot GAL3 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Kidney cancer cell CAKI-2 IHC, Western blot GAL3 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Renal cell adenocarcinoma cell 786-O IHC, Western blot GAL3 23917726 Kidney-cancer Homo sapiens Inhibit Galectin-3-(gal-3)-inhibition synergy Upregulation Cancer Biol Ther Renal cell adenocarcinoma cell ACHN IHC, Western blot GALNT3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GALNTL4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Gamma glutamylcysteine synthetase 27335833 Liver-toxicity Mus musculus Induce - - Upregulation ISRN Hepatol - - Western blot GARNL1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GARNl3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GARS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GAS1 27521572 Sarcoma Homo sapiens Inhibit Vincristine synergy Downregulation Cancer Lett Rhabdomyosarcoma cell RD QRT-PCR GAS1 27521572 Rhabdomyosarcoma Homo sapiens Inhibit Vincristine synergy Downregulation Cancer Lett Alveolar hrabdomyosarcomas cell RH-30 QRT-PCR GAS1 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Rhabdoid tumor cell G-401 QRT-PCR GAS1 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Liver cancer cell Lachenmeier QRT-PCR GAS1 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Large cell lung cancer cell NCI-H460 QRT-PCR, Western blot GAS1 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot GATA1 16360329 Leukemia Homo sapiens Inhibit - - Downregulation Blood Cells Mol Dis Chronic myelogenous leukemia cell K-562 Western blot GATA1 16360329 Leukemia Homo sapiens Inhibit - - Downregulation Blood Cells Mol Dis Erythroleukemia cell HEL Western blot GATA1 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot GATA1 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot GATA2 16360329 Leukemia Homo sapiens Inhibit - - Upregulation Blood Cells Mol Dis Chronic myelogenous leukemia cell K-562 Western blot GATA2 16360329 Leukemia Homo sapiens Inhibit - - Upregulation Blood Cells Mol Dis Erythroleukemia cell HEL Western blot Gata4 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR Gata4 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - Western blot GATA4 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a Western blot Gata6 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR Gba2 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR Gclc 29049341 Immune-toxicity Mus musculus Induce - - Upregulation PLoS One Splenocyte Splenocytes QRT-PCR GCLC 25344162 Vascular-toxicity Homo sapiens Induce - - Downregulation Mutat Res Genet Toxicol Environ Mutagen Bronchial epithelial cell HBE Western blot GCLC 25341331 Liver-cancer Homo sapiens Inhibit - - Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Western blot GCLC 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Downregulation Environ Mol Mutagen Bronchial epithelial cell HBE Western blot GCLM 22178533 Ovary-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharm Sci Ovarian cancer cell OVCAR-3 QRT-PCR GCLM 25341331 Liver-cancer Homo sapiens Inhibit - - Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Western blot GCLM 25339131 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Downregulation Environ Mol Mutagen Bronchial epithelial cell HBE Western blot GDF15 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GDF2 25076250 Esophageal-cancer Homo sapiens Inhibit - - Upregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR GDF3 25076250 Esophageal-cancer Homo sapiens Inhibit - - Downregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR GDF3 25076250 Gastric-cancer Homo sapiens Inhibit - - Upregulation Tumori Gastric adenocarcinoma cell SGC-7901 QRT-PCR GDF3 25076250 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Tumori Pancreatic cancer cell BxPC-3 QRT-PCR GDF3 25076250 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Tumori Colorectal cancer cell LS 174 QRT-PCR GDNF 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GFAP 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Tumour Biol Glioblastoma cell U-87 MG IFA GFAP 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Tumour Biol Likely glioblastoma cell U-87 MG IFA GFP 24416773 Acquired immunodeficiency syndrome Homo sapiens Inhibit - - Upregulation Antiviral Res Leukemia cell C11 Flow cytometry GGH 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GGTL4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GIGYF2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GINS2 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute monocytic leukemia cell THP-1 QRT-PCR GINS2 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR GINS2 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR Gja1 17559834 Vascular-toxicity Rattus norvegicus Induce - - Downregulation Eur J Pharmacol - - Western blot GJA1 28094846 Heart-toxicity Homo sapiens Induce - - Downregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Microarray analysis GJA1 17559834 Vascular-toxicity Homo sapiens Induce - - Downregulation Eur J Pharmacol Aortic endothelial cell HAECs Western blot GJA8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GJB1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 QRT-PCR GJB1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B QRT-PCR GJB7 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GJC1 28094846 Heart-toxicity Homo sapiens Induce - - Downregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Microarray analysis GLCM 25344162 Vascular-toxicity Homo sapiens Induce - - Downregulation Mutat Res Genet Toxicol Environ Mutagen Bronchial epithelial cell HBE Western blot Gli1 31612257 Renal-fibrosis Rattus norvegicus Inhibit - - Downregulation Naunyn Schmiedebergs Arch Pharmacol - - ELISA GLI1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 PCR Array, Western blot GLI1 30983542 Pancreas-cancer Homo sapiens Inhibit Erlotinib synergy Downregulation J Chemother Pancreatic cancer cell PANC-1 QRT-PCR GLI1 27521572 Rhabdomyosarcoma Homo sapiens Inhibit Vincristine synergy Downregulation Cancer Lett Alveolar hrabdomyosarcomas cell RH-30 QRT-PCR GLI1 25082385 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Osteosarcoma cell 143B QRT-PCR GLI1 25082385 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Hs-os-1 cell HS-OS-1 QRT-PCR GLI1 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Rhabdoid tumor cell G-401 QRT-PCR GLI1 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Liver cancer cell Lachenmeier QRT-PCR GLI1 23867347 Leukemia Homo sapiens Inhibit - - Downregulation Acta Haematol Acute promyelocytic leukemia cell NB4 QRT-PCR GLI1 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell 143B QRT-PCR GLI1 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell Saos-2 QRT-PCR GLI1 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell U-2 OS QRT-PCR GLI1 27784375 Myeloma Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell NCI-H929 QRT-PCR,Western blot GLI1 26458318 Prostate-cancer Homo sapiens Inhibit Cyclopamine synergy Downregulation Neoplasma Prostate carcinoma cell PC-3 QRT-PCR,Western blot, IFA GLI1 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Large cell lung cancer cell NCI-H460 QRT-PCR, Western blot GLI1 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot GLI1 25945059 Colorectal-cancer Homo sapiens Inhibit Ly294002 synergy Downregulation Onco Targets Ther Colorectal adenocarcinoma cell HT-29 QRT-PCR, Western blot GLI1 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H446 Western blot GLI1 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-209(CSCs) Western blot GLI1 28823259 Leukemia Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot GLI1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell RD Western blot GLI1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell CCA Western blot GLI1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell RUCH3 Western blot GLI1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Alveolar hrabdomyosarcomas cell RH-30 Western blot GLI1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell ZF Western blot GLI1 25577250 Bone-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot GLI1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B Western blot Gli2 31612257 Renal-fibrosis Rattus norvegicus Inhibit - - Downregulation Naunyn Schmiedebergs Arch Pharmacol - - ELISA Gli2 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR GLI2 27521572 Rhabdomyosarcoma Homo sapiens Inhibit Vincristine synergy Downregulation Cancer Lett Alveolar hrabdomyosarcomas cell RH-30 QRT-PCR GLI2 25945059 Colorectal-cancer Homo sapiens Inhibit Ly294002 synergy Downregulation Onco Targets Ther Colorectal adenocarcinoma cell HT-29 QRT-PCR GLI2 25082385 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Osteosarcoma cell 143B QRT-PCR GLI2 25082385 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Hs-os-1 cell HS-OS-1 QRT-PCR GLI2 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell HSR-GBM1 QRT-PCR GLI2 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR GLI2 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40821 QRT-PCR GLI2 23867347 Leukemia Homo sapiens Inhibit - - Downregulation Acta Haematol Acute promyelocytic leukemia cell NB4 QRT-PCR GLI2 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell 143B QRT-PCR GLI2 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell Saos-2 QRT-PCR GLI2 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell U-2 OS QRT-PCR GLI2 28823259 Leukemia Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot GLI2 25577250 Bone-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot GLO1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GLS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GLTP 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Glut4 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Downregulation Int J Biochem Cell Biol - - Western blot Glut4 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Downregulation Int J Biochem Cell Biol Myoblast cell C2C12 Western blot GNRH2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GOLGA2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GOSR2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis GOSR2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis GOT1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GOT2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GP1BB 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GP46 21038850 Leukemia Homo sapiens Inhibit - - Downregulation Pharmazie HTLV-1 infected cell Htlv-1 infected cell Western blot GP62 19571400 Lymphoma Homo sapiens Inhibit - - Downregulation Biol Pharm Bull T cell leukemia cell MT-2 Western blot GPC6 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GPR15 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GPSM3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis gpx 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Gpx 19888912 Heart-toxicity Cavia porcellus Induce Vitamin-C detoxicity Upregulation J Environ Pathol Toxicol Oncol - - Kit GPX 17957129 Melanoma Homo sapiens Inhibit - - Downregulation Ophthalmic Res Uveal melanoma cell OCM-1 Kit GPX 29214213 Liver-cancer Homo sapiens Inhibit - - Downregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Kit GPX 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - Kit GPX 25982179 Leukemia Homo sapiens Inhibit Dichloroacetate synergy Downregulation Leuk Res Primary acute promyelocytic leukemia cell Primary APL cell Western blot Gpx1 28092839 Heart-toxicity Mus musculus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother - - Kit Gpx1 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother Heart myoblast H9C2 Kit GPX4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GPX7 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GRB10 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GRB10 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR GRB2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GRB2 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR GRB2 23178716 Ovary-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Ovarian carcinoma cell HEY Western blot GREB1 22558281 Breast-cancer Homo sapiens Inhibit - - Upregulation PLoS One Breast cancer cell MDA-MB-231 RT-PCR GREB1 22558281 Breast-cancer Homo sapiens Inhibit - - Upregulation PLoS One Breast cancer cell Hs 578T RT-PCR Gria1 24831965 Neuronal-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR Gria2 24831965 Neuronal-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR GRIK1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis GRIK4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Grin1 24831965 Neuronal-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR Grm1 24831965 Neuronal-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR GRO 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay GRP 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Grp78 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Grp78 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Grp78 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget - - Western blot Grp78 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Grp78 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Grp78 27461142 Immune-toxicity Mus musculus Induce - - Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot Grp78 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Molecules Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Grp78 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Molecules - - Western blot Grp78 23494705 Asthma Mus musculus Inhibit - - Upregulation Ir J Med Sci Spleen cell Mouse CD4+ T cell Western blot GRP78 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot GRP78 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell SMMC-7721 QRT-PCR,Western blot GRP78 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot GRP78 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot GRP78 19878647 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Polymorphonuclear neutrophils cell Polymorphonuclear neutrophils RT-PCR GRP78 21181559 Liver-cancer Homo sapiens Inhibit - - Upregulation Ann Surg Oncol Hepatocellular carcinoma cell Hep-J5 Western blot GRP78 26772155 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Chem Biol Interact Lung adenocarcinoma cell A549 Western blot GRP78 26494474 Head-and-neck-cancer Homo sapiens Inhibit Dithiothreitol synergy Upregulation Environ Toxicol Oral cancer cell Primarily cultured cell Western blot GRP78 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot GRP78 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot GRP78 23880367 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Auris Nasus Larynx Hela carcinoma cell HEP-2 Western blot Grp94 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Grp94 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR, Western blot Grp94 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot GRP94 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Western blot GRP94 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Western blot GSDM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GSDME 31637008 Liver-cancer Homo sapiens Inhibit - - Upregulation Signal Transduct Target Ther Liver cancer cell Huh7 Western blot Gsh 18393359 Lung-cancer Homo sapiens Inhibit - - Downregulation J Cell Biochem Lung cancer cell CALU-6 Flow cytometry Gsh 18393359 Lung-cancer Homo sapiens Inhibit - - Downregulation J Cell Biochem Lung adenocarcinoma cell A549 Flow cytometry Gsh 18247324 Kidney-toxicity Mus musculus Induce - - Downregulation J Cell Biochem Kidney cell AS4.1 Flow cytometry Gsh 19888912 Heart-toxicity Cavia porcellus Induce Vitamin-C detoxicity Upregulation J Environ Pathol Toxicol Oncol - - Kit Gsh 16716044 Kidney-toxicity Rattus norvegicus Induce - - Downregulation Toxicol Ind Health - - Kit GSH 31355259 Liver-toxicity Homo sapiens Induce Proanthocyanidins detoxicity Downregulation Biomed Res Int Embryo hepatocyte L-O2 ELISA GSH 16115949 Myeloma Homo sapiens Inhibit (-)-Epigallocatechin-3-gallate synergy Downregulation Clin Cancer Res Multiple myeloma cell IM-9 Flow cytometry GSH 16237756 Liver-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Hepatocellular carcinoma cell HEPG2 Kit GSH 16237756 Liver-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Hepatocellular carcinoma cell HEP3B Kit GSH 16237756 Breast-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Breast cancer cell MCF7 Kit GSH 16237756 Lung-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Lung adenocarcinoma cell AGZY-83-A Kit GSH 19846917 Lung-cancer Homo sapiens Inhibit SP600125 - Upregulation Anticancer Res Lung cancer cell CALU-6 Kit GSH 19846917 Lung-cancer Homo sapiens Inhibit Pd98059 - Upregulation Anticancer Res Lung cancer cell CALU-6 Kit GSH 19846917 Lung-cancer Homo sapiens Inhibit SB203580 - Upregulation Anticancer Res Lung cancer cell CALU-6 Kit GSH 19574005 Laryngeal-cancer Homo sapiens Inhibit L-buthionine-s,r-sulfoximine synergy Downregulation Auris Nasus Larynx Hela carcinoma cell HEP-2 Kit GSH 27592447 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Osteosarcoma cell MG-63 Kit GSH 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - Kit Gsk 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Upregulation Int J Biochem Cell Biol - - Western blot GSK3 23352504 Cervical-cancer Homo sapiens Inhibit Ly294002 synergy Phosphorylation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot GSK3A 18566239 Leukemia Homo sapiens Inhibit - - Dephosphorylation Mol Cancer Ther Acute promyelocytic leukemia cell NB4 Western blot GSK3A 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Dephosphorylation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot GSK3A 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Dephosphorylation Leukemia Chronic myelogenous leukemia cell K-562 Western blot GSK3B 22751450 Leukemia Homo sapiens Inhibit - - Dephosphorylation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot GSK3B 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Toxicol Sci Epidermoid carcinoma cell A-431 Western blot GSK3B 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Toxicol Sci Keratinocyte HACAT Western blot GSK3B 19242099 Brain-cancer Homo sapiens Inhibit Irradiation synergy Phosphorylation Autophagy Glioblastoma cell U-118MG Western blot GSK3B 27671604 Heart-toxicity Homo sapiens Induce - - Phosphorylation Sci Rep Aortic endothelial cell HAECs Western blot GSK3B 27010069 Leukemia Homo sapiens Inhibit - - Phosphorylation Sci Rep Acute promyelocytic leukemia cell HL-60 Western blot GSK3B 27010069 Leukemia Homo sapiens Inhibit - - Phosphorylation Sci Rep Acute promyelocytic leukemia cell NB4 Western blot GSK3B 26966376 Prostate-cancer Homo sapiens Inhibit - - Upregulation Onco Targets Ther Prostate carcinoma cell LNCaP Western blot GSK3B 26966376 Prostate-cancer Homo sapiens Inhibit - - Upregulation Onco Targets Ther Prostate carcinoma cell PC-3 Western blot GSK3B 30763586 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Phosphorylation,Downregulation Exp Cell Res Histiocytic lymphoma cell U-937 Western blot GSK3B 30213730 Leukemia Homo sapiens Inhibit - - Phosphorylation,Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot GSK3B 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation,Phosphorylation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot GSK3B 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Dephosphorylation Tumour Biol Liver cancer cell Huh7 Western blot GSK3B 25246272 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Neoplasia Prostate adenocarcinoma cell PC-3 Western blot GSK3B 25246272 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Neoplasia Prostate carcinoma cell DU 145 Western blot GSK3B 24791595 Leukemia Homo sapiens Inhibit - - Phosphorylation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot GSK3B 24482137 Gastric-cancer Homo sapiens Inhibit - - Dephosphorylation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot GSN 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Liver cancer cell Huh7.5.1 QRT-PCR GSN 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR GSPT2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis GSS 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling Gst 25966753 Reproductive-toxicity Mus musculus Induce Grape-seed-proanthocyanidin detoxicity Upregulation Biomed Environ Sci - - QRT-PCR Gst 26187899 Reproductive-toxicity Mus musculus Induce Lutein detoxicity Upregulation Hum Exp Toxicol - - RT-PCR Gst 27335833 Liver-toxicity Mus musculus Induce - - Upregulation ISRN Hepatol - - Western blot GST 16237756 Liver-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Hepatocellular carcinoma cell HEPG2 Kit GST 16237756 Liver-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Hepatocellular carcinoma cell HEP3B Kit GST 16237756 Breast-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Breast cancer cell MCF7 Kit GST 16237756 Lung-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Lung adenocarcinoma cell AGZY-83-A Kit GST 18050736 Gastric-cancer Homo sapiens Inhibit - - Downregulation Yao Xue Xue Bao Gastric adenocarcinoma cell SGC-7901 Western blot GST-PI 12408759 Breast-cancer Homo sapiens Inhibit - - Downregulation Zhonghua Zhong Liu Za Zhi Breast cancer cell MCF7 RT-PCR GSTA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GSTA3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GSTM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis GSTP1 16613325 Liver-cancer Homo sapiens Inhibit - - Upregulation Hum Pathol Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot GSTT1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis H2ax 23337567 Bone-cancer Rattus norvegicus Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot H2AX 30946857 Heart-toxicity Homo sapiens Induce - - Upregulation Toxicol Lett Pluripotent stem cell hiPS IFA H2AX 29048129 Myeloma Homo sapiens Inhibit - - Upregulation,Phosphorylation Br J Haematol Myeloma cell MM.1S Western blot H2AX 29048129 Myeloma Homo sapiens Inhibit - - Upregulation,Phosphorylation Br J Haematol Myeloma cell RPMI 8226-S Western blot H2AX 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/GGT Western blot H2AX 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/BASAL Western blot H2AX 16891316 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot H2AX 30012499 Leukemia Homo sapiens Inhibit Ruxolitinib synergy Phosphorylation Eur J Pharmacol Histiocytic lymphoma cell U-937 Western blot H2AX 25150315 Melanoma Homo sapiens Inhibit - - Upregulation Neoplasma Melanoma cell BOWES Western blot H2AX 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell 143B Western blot H2AX 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell Saos-2 Western blot H2AX 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell U-2 OS Western blot H2AX 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot H2AX 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot H2AX 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot, IFA H3 29048129 Myeloma Homo sapiens Inhibit - - Phosphorylation Br J Haematol Myeloma cell MM.1S Western blot H3 29048129 Myeloma Homo sapiens Inhibit - - Phosphorylation Br J Haematol Myeloma cell RPMI 8226-S Western blot H3 16762916 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Leukemia cell KT1 Western blot H4 31472347 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - Western blot H4 27189198 Leukemia Homo sapiens Inhibit Vorinostat synergy Downregulation J Int Med Res Acute promyelocytic leukemia cell NB4 Western blot has-let-7b 23373993 Eye-cancer Homo sapiens Inhibit - - Downregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR HAS2 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HAUS6 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HAVCR2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HBA 26170775 Leukemia Homo sapiens Inhibit - - Downregulation Bioinorg Chem Appl Chronic myelogenous leukemia cell K-562 QRT-PCR HBB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HBB 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HBB 26170775 Leukemia Homo sapiens Inhibit - - Downregulation Bioinorg Chem Appl Chronic myelogenous leukemia cell K-562 QRT-PCR HBEGF 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HBG 26170775 Leukemia Homo sapiens Inhibit - - Downregulation Bioinorg Chem Appl Chronic myelogenous leukemia cell K-562 QRT-PCR HBP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HBXIP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HDAC1 25815518 Myeloma Homo sapiens Inhibit Valproic Acid synergy Downregulation Mol Med Rep Myeloma cell RPMI 8226 RT-PCR HDAC6 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot HECA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis her2 29515638 Liver-cancer Mus musculus Induce Curcumin detoxicity Upregulation Iran J Pathol - - QRT-PCR HERC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Herg 28525371 Heart-toxicity Mus musculus Induce - - Downregulation Oncotarget Primary neonatal mouse cardiomyocyte Cardiomyocyte Western blot Herg 22853924 Heart-toxicity Rattus norvegicus Induce - - Downregulation Cardiovasc Res Neonatal cardiac fibroblast Cardiac fibroblasts Western blot HERG 28521025 Heart-toxicity Homo sapiens Induce - - Downregulation Toxicol Sci Embryonic kidney cell HEK-293 IFA HERG 25824027 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Breast cancer cell MCF7 QRT-PCR,Western blot HERG 23103450 Heart-toxicity Homo sapiens Induce Matrine detoxicity Downregulation Biochem Pharmacol Embryonic kidney cell HEK-293 Western blot HERG 23103450 Heart-toxicity Homo sapiens Induce Oxymatrine detoxicity Downregulation Biochem Pharmacol Embryonic kidney cell HEK-293 Western blot HERG 22977528 Breast-cancer Homo sapiens Inhibit - - Downregulation Exp Ther Med Breast cancer cell MCF7 Western blot HERG 25355491 Brain-cancer Homo sapiens Inhibit - - Downregulation J Mol Neurosci Glioma cell U251 Western blot HERG 28768059 Heart-toxicity Homo sapiens Induce (-)-Epicatechin detoxicity Downregulation J Biochem Mol Toxicol Embryonic kidney cell HEK-293 Western blot, Patch clamp HERG 30127993 Breast-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Embryonic kidney cell HEK-293 Western blot, Patch clamp HERPUD1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis HERPUD1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis HES1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HES1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis HES1 23497375 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Cell Int Myeloma cell RPMI 8226 QRT-PCR HES1 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Cancer stem-like cell GBM neurospheres RT-PCR HES1 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG RT-PCR HES1 31093499 Lung-cancer Homo sapiens Inhibit - - Downregulation Biomed Res Int Human umbilical vein endothelial cells HUVECs Western blot HES1 31093499 Lung-cancer Homo sapiens Inhibit - - Downregulation Biomed Res Int Small cell lung cancer cell NCI-H69 Western blot HES1 19962820 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioblastoma cell U-87 MG Western blot HES1 19962820 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell U251MG Western blot HES1 19962820 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell U373MG Western blot HES5 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell HSR-GBM1 QRT-PCR, Western blot HES5 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR, Western blot HES5 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40821 QRT-PCR, Western blot HEY1 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell HSR-GBM1 QRT-PCR, Western blot HEY1 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR, Western blot HEY1 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40821 QRT-PCR, Western blot HEY1 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Cancer stem-like cell GBM neurospheres RT-PCR HEY1 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG RT-PCR Hf1a 24756364 Liver-cancer Rattus norvegicus Inhibit - - Upregulation J Cancer Res Clin Oncol Hepatoma cell MCA-RH7777 Western blot HHIP 27521572 Sarcoma Homo sapiens Inhibit Vincristine synergy Downregulation Cancer Lett Rhabdomyosarcoma cell RD QRT-PCR HHIP 27521572 Rhabdomyosarcoma Homo sapiens Inhibit Vincristine synergy Downregulation Cancer Lett Alveolar hrabdomyosarcomas cell RH-30 QRT-PCR HHIP 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Rhabdoid tumor cell G-401 QRT-PCR HHIP 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Liver cancer cell Lachenmeier QRT-PCR HHLA3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Hif1a 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol CD4+T cell CD4+T cell QRT-PCR Hif1a 15888669 Melanoma Mus musculus Inhibit - - Upregulation Toxicol Sci Melanoma cell B16-F10 Western blot, IHC HIF1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HIF1A 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis HIF1A 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Lung cancer cell SK-MES-1 RT-PCR HIF1A 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Lung adenocarcinoma cell A549 RT-PCR, Western blot HIF1A 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Large cell lung cancer cell NCI-H460 RT-PCR, Western blot HIF1A 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Small cell lung cancer cell NCI-H446 RT-PCR, Western blot HIF1A 22093145 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Cancer Breast epithelial carcinoma cell T-47D Western blot HIF1A 21181559 Liver-cancer Homo sapiens Inhibit - - Upregulation Ann Surg Oncol Hepatocellular carcinoma cell Hep-J5 Western blot HIF1A 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-1690 Western blot HIF1A 19139125 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Acute promyelocytic leukemia cell NB4 Western blot HIF1A 26692822 Liver-cancer Homo sapiens Inhibit 5-fluorouracil synergy Downregulation Cancer Cell Int Hepatocellular carcinoma cell HEPG2 Western blot HIF1A 15888669 Bladder-cancer Homo sapiens Inhibit - - Upregulation Toxicol Sci Microvascular endothelial cell HMEC-1 Western blot HIF1A 15888669 Bladder-cancer Homo sapiens Inhibit - - Upregulation Toxicol Sci Bladder carcinoma cell J82 Western blot HIG1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HIP55 15637062 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Northern blot, Western blot HIPK1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Hipk2 33254717 Brain-toxicity Rattus norvegicus Induce - - Upregulation Environ Pollut - - QRT-PCR, Western blot HIST1H2BK 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR HIST2H2AA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HIST2H2AC 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HISTONE 11520058 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot HISTONE H1 12181429 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Pharmacol Breast cancer cell MCF7 Western blot HISTONE H13 PS10 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Downregulation Int J Oncol Rhabdomyosarcoma cell SRH Western blot HISTONE H13 PS10 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell RD Western blot HISTONE H13 PS10 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Alveolar hrabdomyosarcomas cell RH-30 Western blot HISTONE H13 PS10 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell ZF Western blot HISTONE H3 28670501 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation Exp Hematol Oncol Cervical adenocarcinoma cell HeLa Western blot HISTONE H3 19781537 Leukemia Homo sapiens Inhibit Paclitaxel synergy Upregulation Chem Biol Interact Leukemia cell Jurkat Western blot, IFA HK2 26598702 Gastric-cancer Homo sapiens Inhibit - - Downregulation Proc Natl Acad Sci U S A Gastric adenocarcinoma cell SGC-7901 Metabolomics analysis HLA-C 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HLA-DPA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HLA-E 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis HMB 26170775 Leukemia Homo sapiens Inhibit - - Downregulation Bioinorg Chem Appl Chronic myelogenous leukemia cell K-562 Western blot HMBS 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HMG1 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis Hmg2 31472347 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - Western blot HMGB1 28404891 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Oncotarget Acute promyelocytic leukemia cell NB4 ELISA HMGB1 28404891 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Oncotarget Acute promyelocytic leukemia cell HL-60 ELISA HMGB1 27807322 Leukemia Homo sapiens Inhibit - - Upregulation Zhong Nan Da Xue Xue Bao Yi Xue Ban Chronic myelogenous leukemia cell K-562 ELISA HMGN2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Hmox1 29049341 Immune-toxicity Mus musculus Induce - - Upregulation PLoS One Splenocyte Splenocytes QRT-PCR HMOX1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HMOX1 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Liver cancer cell Huh7.5.1 QRT-PCR HMOX1 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR HMOX1 17258074 Kidney-toxicity Homo sapiens Induce Alpha-lipoic acid detoxicity Upregulation Exp Hematol Embryonic renal cell PRCC QRT-PCR HMOX1 17258074 Kidney-toxicity Homo sapiens Induce Alpha-lipoic acid detoxicity Upregulation Exp Hematol Embryonic kidney cell HEK-293 QRT-PCR HMOX1 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Upregulation PLoS One Acute promyelocytic leukemia cell NB4 RT-PCR HMOX1 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Upregulation PLoS One Primary acute promyelocytic leukemia cell Primary APL cell RT-PCR HMOX1 19417148 Myeloma Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Multiple myeloma cell KMS-11 Western blot HMOX2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HNRNPA1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HNRNPH1 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis HNRNPK 19747914 Leukemia Homo sapiens Inhibit - - Downregulation Exp Cell Res Histiocytic lymphoma cell U-937 Western blot HNRPA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HNRPH1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HNRPH2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HNRPR 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ho1 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - Western blot Ho1 31135953 Acute graft-versus-host-disease Mus musculus Inhibit - - Upregulation Br J Haematol - - IHC, Western blot Ho1 31473893 Liver-toxicity Mus musculus Induce - - Upregulation Biol Trace Elem Res - - QRT-PCR Ho1 25966753 Reproductive-toxicity Mus musculus Induce Grape-seed-proanthocyanidin detoxicity Upregulation Biomed Environ Sci - - QRT-PCR HO1 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Environ Pollut - - QRT-PCR HO1 28776567 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Leukemia Acute promyelocytic leukemia cell NB4 QRT-PCR HO1 24327821 Heart-toxicity Rattus norvegicus Induce Resveratrol detoxicity Downregulation Evid Based Complement Alternat Med - - QRT-PCR HO1 31442540 Liver-toxicity Gallus gallus Induce - - - Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR,Western blot HO1 30317545 Skin-toxicity Homo sapiens Induce - - Upregulation J Cell Physiol Primary skin fibroblast Primary skin fibroblast QRT-PCR,Western blot HO1 26283888 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Med Sci Osteosarcoma cell U-2 OS QRT-PCR,Western blot HO1 28978146 Liver-toxicity Rattus norvegicus Induce Eriodictyol detoxicity Upregulation Oncotarget - - QRT-PCR, Western blot HO1 22488045 Immune-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR, Western blot HO1 26283888 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Med Sci Osteosarcoma cell MG-63 QRT-PCR, Western blot HO1 25815309 Liver-toxicity Mus musculus Induce Lutein detoxicity Upregulation Biomed Res Int - - QRT-PCR, Western blot HO1 24676542 Bone-cancer Homo sapiens Inhibit - - Upregulation Mol Cell Biochem Osteosarcoma cell MG-63 QRT-PCR, Western blot HO1 24676542 Bone-cancer Homo sapiens Inhibit - - Upregulation Mol Cell Biochem Osteosarcoma cell U-2 OS QRT-PCR, Western blot HO1 24676542 Bone-cancer Homo sapiens Inhibit - - Upregulation Mol Cell Biochem Human umbilical vein endothelial cells HUVECs QRT-PCR, Western blot HO1 26187899 Reproductive-toxicity Mus musculus Induce Lutein detoxicity Upregulation Hum Exp Toxicol - - RT-PCR HO1 27608960 Heart-toxicity Rattus norvegicus Induce Imperatorin detoxicity Upregulation Toxicol In Vitro Heart myoblast H9C2 RT-PCR, Western blot HO1 27608960 Heart-toxicity Rattus norvegicus Induce Sec-o-glucosylhamaudol detoxicity Upregulation Toxicol In Vitro Heart myoblast H9C2 RT-PCR, Western blot HO1 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot HO1 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute monocytic leukemia cell THP-1 RT-PCR, Western blot HO1 29260515 Lung-cancer Homo sapiens Inhibit - - Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Lung adenocarcinoma cell A549 Western blot HO1 20950636 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Acute promyelocytic leukemia cell HL-60 Western blot HO1 19342982 Pancreas-cancer Homo sapiens Inhibit Parthenolide synergy Upregulation Pancreas Pancreatic cancer cell PANC-1 Western blot HO1 19342982 Pancreas-cancer Homo sapiens Inhibit Parthenolide synergy Upregulation Pancreas Pancreatic cancer cell BXPC-3 Western blot HO1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Myeloma cell U266 Western blot HO1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Myeloma cell RPMI 8226 Western blot HO1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Myeloma cell MM.1S Western blot HO1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Multiple myeloma cell KMS-11 Western blot HO1 18636201 Lung-cancer Homo sapiens Inhibit Sulindac synergy Upregulation Oncol Rep Lung cancer cell NCI-H157 Western blot HO1 17690699 Liver-toxicity Mus musculus Induce Trolox detoxicity Upregulation Leukemia Lymphoma cell P388 Western blot HO1 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother Heart myoblast H9C2 Western blot HO1 27980225 Liver-toxicity Rattus norvegicus Induce Melatonin detoxicity Upregulation Oncotarget - - Western blot HO1 27713174 Liver-toxicity Rattus norvegicus Induce Oxymatrine detoxicity Upregulation Oncotarget - - Western blot HO1 27592447 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Osteosarcoma cell MG-63 Western blot HO1 27561292 Liver-toxicity Rattus norvegicus Induce Allicin detoxicity Downregulation Biol Trace Elem Res - - Western blot HO1 27263286 Liver-cancer Homo sapiens Inhibit Aspirin synergy Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Western blot HO1 17258074 Kidney-toxicity Homo sapiens Induce Alpha-lipoic acid detoxicity Upregulation Exp Hematol Embryonic renal cell PRCC Western blot HO1 17258074 Kidney-toxicity Homo sapiens Induce Alpha-lipoic acid detoxicity Upregulation Exp Hematol Embryonic kidney cell HEK-293 Western blot HO1 29662624 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Primary s1 glioblastoma cell S1 GBM Western blot HO1 15466933 Leukemia Homo sapiens Inhibit Trolox synergy Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot HO1 15466933 Leukemia Homo sapiens Inhibit Trolox synergy Upregulation Blood Multiple myeloma cell IM-9 Western blot HO1 25246272 Retinoblastoma Homo sapiens Inhibit - - Upregulation Neoplasia Retinoblastoma cell Y79 Western blot HO1 25246272 Prostate-cancer Homo sapiens Inhibit - - Upregulation Neoplasia Prostate adenocarcinoma cell PC-3 Western blot HO1 25246272 Prostate-cancer Homo sapiens Inhibit - - Upregulation Neoplasia Prostate carcinoma cell DU 145 Western blot HO1 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute promyelocytic leukemia cell NB4 Western blot HO1 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute promyelocytic leukemia cell NB4 Western blot HO1 23285138 Myeloma Homo sapiens Inhibit - - Upregulation PLoS One Myeloma cell RPMI 8226 Western blot HO1 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Oral squamous cell carcinoma cell Tca-8113 Western blot, IFA HO1 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Tongue squamous cell carcinoma cell SCC-4 Western blot, IFA HO1 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Tongue squamous cell carcinoma cell SCC-15 Western blot, IFA HOMOLOG 1 24137378 Breast-cancer Homo sapiens Inhibit - - Upregulation Oncol Lett Breast cancer cell MCF7 Western blot HOXA9 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Oncotarget Acute myeloid leukemia cell MOLM14 QRT-PCR HOXA9 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Oncotarget Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR HOXA9 28961318 Leukemia Homo sapiens Inhibit - - Downregulation Cell Biochem Funct Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot HOXA9 28961318 Leukemia Homo sapiens Inhibit - - Downregulation Cell Biochem Funct Acute lymphoblastic leukemia cell MOLT-3 QRT-PCR, Western blot HOXA9 22541086 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot HOXB8 25855932 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Eur Rev Med Pharmacol Sci Blood cell CD34+ progenitor QRT-PCR, Western blot HPCA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HPCAL1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HPGD 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HPS3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Hrb 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR Hrd1 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR Hrd1 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR HRK 20471514 Leukemia Homo sapiens Inhibit Bortezomib synergy Upregulation Cancer Genet Cytogenet Acute promyelocytic leukemia cell HL-60 QRT-PCR HRMT1L2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HS3ST6 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HS90B 28466809 Leukemia Homo sapiens Inhibit - - Upregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS hsa-miR-1 22889704 Heart-toxicity Cavia porcellus Induce - - Upregulation Int J Cardiol - - QRT-PCR hsa-miR-1 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-1 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-100 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-100 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-106a 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell HL-60 QRT-PCR hsa-miR-106a 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-107 22967415 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-10a 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-10b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-10b 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-122 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-122 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-124 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-124 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-125a-3p 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-125a-5p 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-125b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-125b 27576314 Bone-cancer Homo sapiens Inhibit - - Upregulation J Exp Clin Cancer Res Articular chondrocyte cell HCS-2/8 QRT-PCR hsa-miR-125b 27576314 Bone-cancer Homo sapiens Inhibit - - Upregulation J Exp Clin Cancer Res Chondrosarcoma cell OUMS-27 QRT-PCR hsa-miR-125b 27576314 Bone-cancer Homo sapiens Inhibit - - Upregulation J Exp Clin Cancer Res Chondrosarcoma cell SW 1353 QRT-PCR hsa-miR-125b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-125b 24479808 Brain-cancer Homo sapiens Inhibit - - Downregulation Curr Pharm Des Glioma cell U251 QRT-PCR hsa-miR-126 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-126 26274316 Vascular-toxicity Homo sapiens Induce - - Upregulation PLoS One Human umbilical vein endothelial cells HUVECs QRT-PCR hsa-miR-126 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-127-5p 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-127-5p 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-128-5p 29662624 Brain-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Primary s1 glioblastoma cell S1 GBM QRT-PCR hsa-miR-128a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-128a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-129-5p 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-130a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-130a 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-132 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-132 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-133 22889704 Heart-toxicity Cavia porcellus Induce - - Upregulation Int J Cardiol - - QRT-PCR hsa-miR-133b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-133b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-133b 25355491 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Neurosci Glioma cell U251 QRT-PCR hsa-miR-134 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-134 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-135b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-135b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-138 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-138 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-13b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-140-5p 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-140-5p 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-141 24729530 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Breast cancer cell MDA-MB-231 QRT-PCR hsa-miR-142-5p 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-142-5p 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-143 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-143 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-144 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-144 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-146a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-146a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-146b-5p 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-146b-5p 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-148a 31759055 Liver-cancer Homo sapiens Inhibit - - Demethylation Exp Cell Res Liver cancer cell BEL-7402 QRT-PCR hsa-miR-148a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-148a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-148b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-148b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-149 22072212 Leukemia Homo sapiens Inhibit - - Downregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-149 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-15 22967415 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-150 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-150 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-153 21267675 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Chronic myelogenous leukemia cell K-562 QRT-PCR hsa-miR-155 29260515 Lung-cancer Homo sapiens Inhibit - - Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Lung adenocarcinoma cell A549 QRT-PCR hsa-miR-155 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-155 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-155 25283513 Prostate-cancer Homo sapiens Inhibit - - Upregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR hsa-miR-155 25283513 Prostate-cancer Homo sapiens Inhibit - - Upregulation Cancer Sci Prostate carcinoma cell LNCaP QRT-PCR hsa-miR-15a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-15a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-15b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-15b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-16 22967415 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-16 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-17 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-17 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell HL-60 QRT-PCR hsa-miR-17 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-17 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-181a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-181b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-181b 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-181b 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-181c 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-181c 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-181d 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-181d 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-183 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-183 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-184 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-184 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-18a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-18a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-18b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-191 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-191 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-193a-5p 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-193a-5p 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-193b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-196a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-196a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-199a-3p 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-199a-3p 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-19a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-19a 20857258 Bladder-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Bladder carcinoma cell T24 QRT-PCR hsa-miR-19a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-200c 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-200c 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-200c 24729530 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Breast cancer cell MDA-MB-231 QRT-PCR hsa-miR-200c 24729530 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Breast cancer cell BT-549 QRT-PCR hsa-miR-203 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-203 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-205 22072212 Leukemia Homo sapiens Inhibit - - Downregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-205 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-206 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-206 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-20a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-20a 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell HL-60 QRT-PCR hsa-miR-20a 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-20b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-20b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-21 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-21 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-210 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-210 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-212 22072212 Leukemia Homo sapiens Inhibit - - Downregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-212 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-214 30982490 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Res Acute myeloid leukemia cell AML-5 QRT-PCR hsa-miR-214 30982490 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Res Acute promyelocytic leukemia cell HL-60 QRT-PCR hsa-miR-214 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-214 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-215 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-215 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-218 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-218 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-220b 23373993 Eye-cancer Homo sapiens Inhibit - - Downregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-222 22072212 Leukemia Homo sapiens Inhibit - - Downregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-222 20857258 Bladder-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Bladder carcinoma cell T24 QRT-PCR hsa-miR-222 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-223 22967415 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-23b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-23b 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-25 22072212 Leukemia Homo sapiens Inhibit - - Downregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-25 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-27a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-27a 26592661 Breast-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Breast cancer cell MDA-MB-231 QRT-PCR hsa-miR-27a 26592661 Breast-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Breast cancer cell SK-BR-3 QRT-PCR hsa-miR-27a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-27b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-27b 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-29a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-29a 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-29b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-29b 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-301a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-301a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-30c 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-32 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-32 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-328 25824027 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Med Rep Breast cancer cell MCF7 QRT-PCR hsa-miR-330-5p 30847385 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Mol Ther Oncolytics Pancreatic cancer cell PATU8988 QRT-PCR hsa-miR-330-5p 30847385 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Mol Ther Oncolytics Pancreatic cancer cell PANC-1 QRT-PCR hsa-miR-335 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-335 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-342 22967415 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-34a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-34a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-34a 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-34c-5p 22072212 Leukemia Homo sapiens Inhibit - - Downregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-34c-5p 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-363 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-363 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-372 22072212 Leukemia Homo sapiens Inhibit - - Downregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-372 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-373 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-373 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-376a 23373993 Eye-cancer Homo sapiens Inhibit - - Downregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-378 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-378 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-425 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-491 25304214 Liver-cancer Homo sapiens Inhibit - - Upregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR hsa-miR-491 25304214 Liver-cancer Homo sapiens Inhibit - - Upregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97H QRT-PCR hsa-miR-491 24680928 Liver-cancer Homo sapiens Inhibit - - Upregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H QRT-PCR hsa-miR-491-3p 23373993 Eye-cancer Homo sapiens Inhibit - - Downregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-524-5p 23373993 Eye-cancer Homo sapiens Inhibit - - Downregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-628-3p 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-649 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-7 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-7 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-766 24356076 Leukemia Homo sapiens Inhibit - - Downregulation Cell Physiol Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-766 24356076 Leukemia Homo sapiens Inhibit - - Downregulation Cell Physiol Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR hsa-miR-890 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-9 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-9 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-92a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-92a 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-943 23373993 Eye-cancer Homo sapiens Inhibit - - Upregulation Neoplasma Retinoblastoma cell HXO-RB44 QRT-PCR hsa-miR-96 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-96 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-98 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR hsa-miR-98 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR hsa-miR-98 25123535 Pulmonary-fibrosis Rattus norvegicus Inhibit - - Upregulation Life Sci - - QRT-PCR hsa-miR-98 25123535 Pulmonary-fibrosis Homo sapiens Inhibit - - Upregulation Life Sci Lung adenocarcinoma cell A549 QRT-PCR HSC70 21038850 Leukemia Homo sapiens Inhibit - - Downregulation Pharmazie HTLV-1 infected cell Htlv-1 infected cell Western blot HSC70 11389037 Leukemia Homo sapiens Inhibit - - Upregulation Blood Acute promyelocytic leukemia cell HL-60 Western blot HSC70 25081691 Lymphoma Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Burkitt's lymphoma cell Raji Western blot Hsd17b1 31313246 Development-toxicity Mus musculus Induce - - Downregulation Biol Trace Elem Res Leydig cell Leydig cell QRT-PCR Hsd3b 31313246 Development-toxicity Mus musculus Induce - - Downregulation Biol Trace Elem Res Leydig cell Leydig cell QRT-PCR HSF1 15978632 Breast-cancer Homo sapiens Inhibit - - Phosphorylation Life Sci Breast cancer cell MDA-MB-231 Western blot HSF2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HSP27 18173754 Myeloma Homo sapiens Inhibit SB203580 synergy Phosphorylation Br J Haematol Myeloma cell RPMI 8226 Flow cytometry, Western blot HSP27 25258189 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis HSP27 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR HSP27 27697713 Neuronal-toxicity Gallus gallus Induce - - Upregulation Chemosphere - - QRT-PCR HSP27 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP27 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP27 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP27 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation,Phosphorylation Leuk Res Myeloma cell RPMI 8226 Western blot HSP27 15665116 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Western blot HSP40 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis HSP40 27697713 Neuronal-toxicity Gallus gallus Induce - - Upregulation Chemosphere - - QRT-PCR HSP40 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP40 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP40 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP40 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR,Western blot HSP40 20724260 Brain-cancer Homo sapiens Inhibit - - Upregulation Can J Neurol Sci Glioma cell U251MG Western blot HSP40 20724260 Brain-cancer Homo sapiens Inhibit - - Upregulation Can J Neurol Sci Glioblastoma cell T98G Western blot HSP60 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP60 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP60 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR HSP60 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR,Western blot HSP60 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot HSP60 27697713 Neuronal-toxicity Gallus gallus Induce - - Upregulation Chemosphere - - QRT-PCR,Western blot HSP60 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot HSP60 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot HSP60 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR, Western blot HSP60 17237268 Leukemia Homo sapiens Inhibit Phytosphingosine synergy Downregulation Mol Cancer Ther Histiocytic lymphoma cell U-937 Western blot hsp70 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - Western blot Hsp70 27335833 Liver-toxicity Mus musculus Induce - - Upregulation ISRN Hepatol - - Western blot Hsp70 17690699 Liver-toxicity Mus musculus Induce Trolox detoxicity Upregulation Leukemia Lymphoma cell P388 Western blot HSP70 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR,Western blot HSP70 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot HSP70 27697713 Neuronal-toxicity Gallus gallus Induce - - Upregulation Chemosphere - - QRT-PCR,Western blot HSP70 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot HSP70 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot HSP70 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR, Western blot HSP70 15978632 Breast-cancer Homo sapiens Inhibit - - Upregulation Life Sci Breast cancer cell MDA-MB-231 RT-PCR, Western blot HSP70 20724260 Brain-cancer Homo sapiens Inhibit - - Upregulation Can J Neurol Sci Glioma cell U251MG Western blot HSP70 20724260 Brain-cancer Homo sapiens Inhibit - - Upregulation Can J Neurol Sci Glioblastoma cell T98G Western blot HSP70 20035426 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Chemother Pharmacol Erythroleukemia cell HEL Western blot HSP70 18359480 Leukemia Homo sapiens Inhibit Quercetin synergy Upregulation Biochem Pharmacol Histiocytic lymphoma cell U-937 Western blot HSP70 17404111 Leukemia Homo sapiens Inhibit - - Upregulation Clin Cancer Res Erythroleukemia cell HEL Western blot HSP70 27592447 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Osteosarcoma cell MG-63 Western blot HSP70 27158419 Lung-cancer Homo sapiens Inhibit - - Upregulation J Cancer Sci Ther Lung adenocarcinoma cell A549 Western blot HSP70 17300860 Brain-cancer Homo sapiens Inhibit Lipoic-acid detoxicity Upregulation Food Chem Toxicol Glioblastoma cell U118 Western blot HSP70 15665116 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Western blot HSP90 22384180 Myeloma Homo sapiens Inhibit - - Upregulation PLoS One Myeloma cell NCI-H929 IHC, Western blot HSP90 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR,Western blot HSP90 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot HSP90 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot HSP90 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot HSP90 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR, Western blot HSP90 22922937 Myeloma Homo sapiens Inhibit Sulforaphane synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot HSP90 22922937 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot HSP90 22922937 Myeloma Homo sapiens Inhibit Erysolin synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot HSP90 27592447 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Osteosarcoma cell MG-63 Western blot Hsp90b1 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR HSPA1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HSPA1B 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis HSPA4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HSPA5 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis HSPA5 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis HSPA5 16249384 Leukemia Homo sapiens Inhibit Imatinib-mesylate synergy Upregulation Blood Chronic myelogenous leukemia cell K-562 Western blot Hspa9 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot HSPB1 12239215 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot HSPCA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HSPCAL3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HSPCB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HSPD1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HTATIP2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot HTATIP2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot HTATIP2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot HTATIP2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot HTATIP2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot HTATIP2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell HCC4006 Western blot HTERT 28533173 Leukemia Homo sapiens Inhibit - - Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR HTERT 22944098 Leukemia Homo sapiens Inhibit - - Downregulation Hematology Acute promyelocytic leukemia cell NB4 QRT-PCR HTERT 27427852 Breast-cancer Homo sapiens Inhibit Melatonin synergy Downregulation Biomed Pharmacother Breast cancer cell MCF7 QRT-PCR HTERT 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR HTERT 17275888 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Endometrial carcinoma cell Ishikawa QRT-PCR HTERT 17275888 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Endometrial carcinoma cell ECC-1 QRT-PCR HTERT 17275888 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Endometrial carcinoma cell RL-95-2 QRT-PCR HTERT 17275888 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Endometrium adenocarcinoma cell HEC-1-B QRT-PCR HTERT 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR HTERT 24161621 Brain-cancer Homo sapiens Inhibit U0126 synergy Downregulation Neurochem Int Neuroblastoma cell SK-N-BE(2) QRT-PCR HTERT 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR HTERT 23293885 Leukemia Homo sapiens Inhibit BIBR1532 synergy Downregulation Anticancer Agents Med Chem Acute promyelocytic leukemia cell NB4 QRT-PCR HTERT 25436934 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Lett Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot HTERT 25415199 Leukemia Homo sapiens Inhibit - - Downregulation PLoS One Myelodysplastic syndrome cell MUTZ-1 QRT-PCR, Western blot HTERT 25415199 Leukemia Homo sapiens Inhibit - - Downregulation PLoS One Myelodysplastic syndrome cell SKM-1 QRT-PCR, Western blot HTERT 16966277 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 RT-PCR HTERT 16107885 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leukemia Acute promyelocytic leukemia cell NB4 RT-PCR HTERT 17956674 Myeloma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell U266 RT-PCR, Western blot HTN3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis HYAL1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Hydin 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR IAP 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Downregulation Leuk Lymphoma Acute myelogenous leukemia cell KG-1a Western blot IAP 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Downregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 Western blot IARS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ICAM1 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast cancer cell MCF7 Flow cytometry,IFA ICAM1 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast cancer cell MDA-MB-231 Flow cytometry,IFA ICAM1 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast epithelial carcinoma cell T-47D Flow cytometry,IFA ICAM1 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast cancer cell BT-20 Flow cytometry,IFA ICAM1 18055984 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Haematologica Acute promyelocytic leukemia cell NB4 IFA ID1 25076250 Esophageal-cancer Homo sapiens Inhibit - - Downregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR ID1 25076250 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Tumori Colorectal cancer cell LS 174 QRT-PCR ID1 31079498 Tongue-cancer Homo sapiens Inhibit - - Downregulation Artif Cells Nanomed Biotechnol Oral squamous cell carcinoma cell Tca-8113 QRT-PCR,Western blot ID2 25076250 Esophageal-cancer Homo sapiens Inhibit - - Upregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR ID2 25076250 Gastric-cancer Homo sapiens Inhibit - - Upregulation Tumori Gastric adenocarcinoma cell SGC-7901 QRT-PCR, Western blot ID2 25076250 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Tumori Pancreatic cancer cell BxPC-3 QRT-PCR, Western blot ID2 25076250 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Tumori Colorectal cancer cell LS 174 QRT-PCR, Western blot ID2 25076250 Esophageal-cancer Homo sapiens Inhibit - - Upregulation Tumori Esophageal squamous carcinoma cell ECA109 Western blot ID3 25076250 Esophageal-cancer Homo sapiens Inhibit - - Upregulation Tumori Esophageal squamous carcinoma cell ECA109 QRT-PCR ID3 25076250 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Tumori Colorectal cancer cell LS 174 QRT-PCR ID4 21223739 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji RT-PCR IER3 30257321 Bladder-cancer Homo sapiens Inhibit Bacillus calmette-guerin synergy Downregulation Biomed Pharmacother Bladder carcinoma cell 5637 QRT-PCR,Western blot IER5L 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IFITM3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IFN 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay Ifnb1 23106696 Immune-toxicity Mus musculus Induce - - Downregulation Cancer Sci Leukemia cell RAW 264.7 Western blot Ifng 27677289 Colorectal-cancer Mus musculus Inhibit - - Upregulation Tumour Biol Cytokine induced killer cell Cytokine induced killer cell ELISA Ifng 26044521 Immune-toxicity Mus musculus Induce - - Downregulation Transpl Immunol - - QRT-PCR Ifng 25919768 Immune-toxicity Mus musculus Induce Rapamycin synergy Downregulation Transplantation - - QRT-PCR Ifng 29159556 Systemic-lupus-erythematosus Mus musculus Inhibit - - Downregulation Biol Trace Elem Res Splenocyte Splenocytes QRT-PCR, ELISA Ifng 29049341 Immune-toxicity Mus musculus Induce - - Downregulation PLoS One Splenocyte Splenocytes QRT-PCR, ELISA Ifng 19545743 Immune-toxicity Mus musculus Induce - - Downregulation Transplant Proc - - RT-PCR IFNG 31380187 SIV-infection Macaca mulatta Inhibit - - Downregulation Adv Sci (Weinh) primary PBMC cell primary PBMC ELISA IFNG 29552182 Immune-toxicity Homo sapiens Induce - - Upregulation Oncol Lett Ascites-derived tumor-infiltrating lymphocyte TILs ELISA IFNG 29159556 Systemic-lupus-erythematosus Homo sapiens Inhibit - - Downregulation Biol Trace Elem Res Peripheral blood mononuclear cell Peripheral blood mononuclear ELISA, QRT-PCR IFNG 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IFNG 31713821 Immune-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR IFNG 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Biol Trace Elem Res - - QRT-PCR IFNG 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR IFNG 23802174 Immune-toxicity Homo sapiens Induce - - Downregulation Immunol Invest Lymphocyte cell ALLOREACTIVE CD4+ MEMORY T CELL QRT-PCR IFRD1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IFRG15 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IGF1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IGF1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR IGF1R 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis IGF1R 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR IGF2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis IGFBP4 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis Igg 27188662 Heart-toxicity Rattus norvegicus Induce Leflunomide synergy Downregulation Xenotransplantation - - Western blot, IHC IGHG1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Igm 27188662 Heart-toxicity Rattus norvegicus Induce Leflunomide synergy Downregulation Xenotransplantation - - Western blot, IHC Ihh 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR IIKAPPABALPHA 15476326 Leukemia Homo sapiens Inhibit - - Downregulation Zhejiang Da Xue Xue Bao Yi Xue Ban Chronic myelogenous leukemia cell K-562 Western blot, Flow cytometry Ikappab 32096187 Heart-toxicity Rattus norvegicus Induce - - Upregulation,Phosphorylation Eur Rev Med Pharmacol Sci Ventricular cardiomyocyte H9c2 QRT-PCR, Western blot Ikappab 28756814 Kidney-toxicity Mus musculus Induce Grape-seed-procyanidin-extract detoxicity Downregulation Biomed Environ Sci - - QRT-PCR, Western blot Ikappab 27664319 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation Regul Toxicol Pharmacol Brain microglia cell HAPI Western blot IKAPPAB 12560223 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Downregulation Blood Lymphoma cell HuT 102 Northern blot IKAPPAB 18575716 Colorectal-cancer Homo sapiens Inhibit Sulindac synergy Dephosphorylation Oncol Rep Colorectal carcinoma cell HCT116 Western blot IKAPPAB 17512576 Cervical-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Cervical adenocarcinoma cell HeLa Western blot IKAPPAB 17512576 Cervical-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Cervix squamous cell carcinoma cell SiHa Western blot IKAPPAB 16734734 Myeloma Homo sapiens Inhibit Anisomycin synergy Phosphorylation Cancer Sci Multiple myeloma cell ILKM-3 Western blot IKAPPAB 16734734 Myeloma Homo sapiens Inhibit Anisomycin synergy Dephosphorylation Cancer Sci Myeloma cell U266 Western blot IKAPPAB 16734734 Myeloma Homo sapiens Inhibit Anisomycin synergy Phosphorylation Cancer Sci Myeloma cell XG-7 Western blot IKAPPAB 29574283 Leukemia Homo sapiens Inhibit Vs-5584 synergy Dephosphorylation Biomed Pharmacother Acute lymphoblastic leukemia cell NALM6 Western blot IKAPPAB 12560223 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Phosphorylation Blood Lymphoma cell HuT 102 Western blot IKAPPAB 12560223 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Upregulation Blood Lymphoma cell HuT 102 Western blot IKAPPAB 11023521 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Upregulation Blood Lymphoma cell HuT 102 Western blot IKAPPAB 11023521 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Upregulation Blood T cell leukemia cell MT-2 Western blot IKAPPAB 26540567 Leukemia Homo sapiens Inhibit - - Phosphorylation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot IKAPPAB 25047463 Cervical-cancer Homo sapiens Inhibit - - Downregulation Ann Surg Oncol Cervical adenocarcinoma cell HeLa Western blot IKAPPAB 24337533 Leukemia Homo sapiens Inhibit - - Phosphorylation Oncol Rep Chronic myelogenous leukemia cell K-562 Western blot IKAPPAB 24337533 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Chronic myelogenous leukemia cell K-562 Western blot Ikappabalpha 28756814 Kidney-toxicity Mus musculus Induce Grape-seed-procyanidin-extract detoxicity Phosphorylation,Downregulation Biomed Environ Sci - - Western blot IKAPPABALPHA 30612216 Breast-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Cell Biol Toxicol Breast cancer cell MDA-MB-231 Western blot IKAPPABALPHA 30612216 Breast-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Cell Biol Toxicol Breast cancer cell Hs 578T Western blot ikba 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - Western blot IKBA 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis Ikbkb 25919768 Immune-toxicity Mus musculus Induce Rapamycin synergy Downregulation Transplantation T cell T cell ELISA IKK2 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR IKK2 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR Ikkbeta 28756814 Kidney-toxicity Mus musculus Induce Grape-seed-procyanidin-extract detoxicity Upregulation Biomed Environ Sci - - QRT-PCR,Western blot IKKBETA 22988968 Breast-cancer Homo sapiens Inhibit - - Upregulation,Downregulation Cancer Biother Radiopharm Breast cancer cell MCF7 RT-PCR, Western blot IKZF1 28927072 Myeloma Homo sapiens Inhibit Lenalidomide synergy Downregulation Oncol Lett Myeloma cell U266 Western blot IKZF3 28927072 Myeloma Homo sapiens Inhibit Lenalidomide synergy Downregulation Oncol Lett Myeloma cell U266 Western blot IL1 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay Il10 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol CD4+T cell CD4+T cell ELISA Il10 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell ELISA Il10 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Melanoma cell B16 ELISA Il10 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol - - IFA Il10 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol - - IFA Il10 27461142 Immune-toxicity Mus musculus Induce - - Downregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 QRT-PCR Il10 26044521 Immune-toxicity Mus musculus Induce - - Upregulation Transpl Immunol - - QRT-PCR IL10 28679299 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Lymphoma T cell Tregs ELISA IL10 29552182 Immune-toxicity Homo sapiens Induce - - Downregulation Oncol Lett Ascites-derived tumor-infiltrating lymphocyte TILs ELISA IL10 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Ecotoxicol Environ Saf - - QRT-PCR IL10 31713821 Immune-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR IL10 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Biol Trace Elem Res - - QRT-PCR IL10 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Int Immunopharmacol - - QRT-PCR IL10 23802174 Immune-toxicity Homo sapiens Induce - - Upregulation Immunol Invest Lymphocyte cell ALLOREACTIVE CD4+ MEMORY T CELL QRT-PCR Il12 20693187 Colitis Mus musculus Inhibit - - Upregulation Innate Immun - - RT-PCR Il12B 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR IL12B 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IL12B 31713821 Immune-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR IL12B 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Biol Trace Elem Res - - QRT-PCR IL13 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay IL15 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IL17 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IL17 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR IL17 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR IL17 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR Il17a 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol CD4+T cell CD4+T cell ELISA Il18 20693187 Colitis Mus musculus Inhibit - - Upregulation Innate Immun - - RT-PCR IL18 31380187 SIV-infection Macaca mulatta Inhibit - - Downregulation Adv Sci (Weinh) primary PBMC cell primary PBMC ELISA IL19 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Il1a 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - QRT-PCR IL1A 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a QRT-PCR il1b 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Fish Shellfish Immunol - - QRT-PCR Il1b 32025748 Heart-toxicity Mus musculus Induce - - Upregulation Naunyn Schmiedebergs Arch Pharmacol - - ELISA Il1b 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Downregulation PPAR Res - - ELISA Il1b 27174766 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Appl Pharmacol Brain microglia cell HAPI ELISA Il1b 27461142 Immune-toxicity Mus musculus Induce - - Downregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 QRT-PCR Il1b 24337744 Immune-toxicity Mus musculus Induce - - Downregulation J Immunol Leukemia cell RAW 264.7 Western blot IL1B 31380187 SIV-infection Macaca mulatta Inhibit - - Downregulation Adv Sci (Weinh) primary PBMC cell primary PBMC ELISA IL1B 28404891 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Oncotarget Acute promyelocytic leukemia cell NB4 ELISA IL1B 28404891 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Oncotarget Acute promyelocytic leukemia cell HL-60 ELISA IL1B 23253724 Skin-toxicity Homo sapiens Induce - - Downregulation Chin Med J (Engl) Acute monocytic leukemia cell THP-1 ELISA IL1B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IL1B 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IL1B 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - QRT-PCR IL1B 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a QRT-PCR IL1B 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR IL1B 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR IL1B 28343272 Leukemia Homo sapiens Inhibit - - Upregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR IL1B 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR IL1B 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR IL1B 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR IL1B 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR IL1B 30237538 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Cell Death Dis Hepatocellular carcinoma cell HEPG2 Western blot IL1R1 22178533 Ovary-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharm Sci Ovarian cancer cell OVCAR-3 QRT-PCR Il2 25919768 Immune-toxicity Mus musculus Induce Rapamycin synergy Downregulation Transplantation T cell T cell ELISA Il2 26044521 Immune-toxicity Mus musculus Induce - - Downregulation Transpl Immunol - - QRT-PCR Il2 25919768 Immune-toxicity Mus musculus Induce Rapamycin synergy Downregulation Transplantation - - QRT-PCR Il2 29049341 Immune-toxicity Mus musculus Induce - - Downregulation PLoS One Splenocyte Splenocytes QRT-PCR, ELISA IL2 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay IL2 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IL2 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR IL2 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR IL2 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR IL2 23802174 Immune-toxicity Homo sapiens Induce - - Downregulation Immunol Invest Lymphocyte cell ALLOREACTIVE CD4+ MEMORY T CELL QRT-PCR IL24 15580305 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell PANC-1 Western blot IL27 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay IL3RA 24791595 Leukemia Homo sapiens Inhibit - - Downregulation Pharmazie Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot Il4 12243866 Leukemia Mus musculus Inhibit - - Downregulation Toxicol Lett Myeloid leukemia cell JCS-16 Northern blot IL4 18357729 Asthma Homo sapiens Inhibit - - Downregulation Yao Xue Xue Bao Peripheral blood cell T cell IFA, ELISA IL4 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IL4 31713821 Immune-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR IL4 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Int Immunopharmacol - - QRT-PCR Il4r 12243866 Leukemia Mus musculus Inhibit - - Downregulation Toxicol Lett Myeloid leukemia cell JCS-16 Northern blot IL5 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay il6 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Fish Shellfish Immunol - - QRT-PCR Il6 32025748 Heart-toxicity Mus musculus Induce - - Upregulation Naunyn Schmiedebergs Arch Pharmacol - - ELISA Il6 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Downregulation PPAR Res - - ELISA Il6 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol CD4+T cell CD4+T cell ELISA Il6 22488045 Immune-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR Il6 22465848 Bone-toxicity Rattus norvegicus Induce - - Downregulation Bone Primary osteoblast progenitor cell Mature asteoblast QRT-PCR, RT-PCR Il6 27664319 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Regul Toxicol Pharmacol Brain microglia cell HAPI RT-PCR, ELISA IL6 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay IL6 31078158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell NB4 Kit IL6 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IL6 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR IL6 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR IL6 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR IL6 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR IL6 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR IL6 30257321 Bladder-cancer Homo sapiens Inhibit Bacillus calmette-guerin synergy Upregulation Biomed Pharmacother Bladder carcinoma cell 5637 QRT-PCR, ELISA IL6 25196641 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H QRT-PCR, ELISA IL6 25196641 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97L QRT-PCR, ELISA IL6 30612216 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Toxicol Breast cancer cell MDA-MB-231 QRT-PCR,Kit IL6 30612216 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Toxicol Breast cancer cell Hs 578T QRT-PCR,Kit IL6 12560223 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Downregulation Blood Lymphoma cell HuT 102 RT-PCR Il7a 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol - - IFA Il7a 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol - - IFA il8 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Fish Shellfish Immunol - - QRT-PCR Il8 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Downregulation PPAR Res - - ELISA IL8 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay IL8 16920938 Immune-toxicity Homo sapiens Induce - - Upregulation J Immunol Peripheral blood mononuclear cell PBMC ELISA IL8 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis IL8 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR IL8 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR IL8 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR IL8 21777978 Lymphoma Homo sapiens Inhibit - - Upregulation Mol Immunol Histiocytic lymphoma cell U-937 QRT-PCR IL8 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR IL8 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR IL8 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR IL8 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR IL8 30257321 Bladder-cancer Homo sapiens Inhibit Bacillus calmette-guerin synergy Upregulation Biomed Pharmacother Bladder carcinoma cell 5637 QRT-PCR, ELISA ILF3 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis IMAGE3451454 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IMAGE4907098 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ING5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis INHBA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Inos 21173536 Neuronal-toxicity Mus musculus Induce - - Downregulation Ind Health - - Microarray analysis Inos 31258454 Development-toxicity Rattus norvegicus Induce - - Upregulation Dose Response - - QRT-PCR Inos 23106696 Immune-toxicity Mus musculus Induce - - Downregulation Cancer Sci Leukemia cell RAW 264.7 QRT-PCR,Western blot Inos 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell RT-PCR Inos 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Melanoma cell B16 RT-PCR Inos 28454374 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Hepatoma cell Heptoma 22 RT-PCR INOS 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR INOS 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot INOS 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot INOS 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot INOS 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot INOS 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR, Western blot INOS 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR, Western blot INOS 25972196 Liver-cancer Homo sapiens Inhibit - - Upregulation J Toxicol Sci Hepatocellular carcinoma cell HEPG2 Western blot INPPl1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ire1 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget - - Western blot Ire1 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot IRE1 17963750 Posterior-capsule-opacification Homo sapiens Inhibit - - Upregulation Exp Eye Res Lens epithelial cell FHL 124 QRT-PCR IRE1 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Osteosarcoma cell HOS Western blot IRE1 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Fibrosarcoma cell HT1080 Western blot IRE1A 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot IRE1A 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot IREB2 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis IRF1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Irf3 23106696 Immune-toxicity Mus musculus Induce - - Dephosphorylation Cancer Sci Leukemia cell RAW 264.7 Western blot IRF7 32642412 Systemic sclerosis Homo sapiens Inhibit - - Downregulation Acta Pharm Sin B Peripheral blood mononuclear cell PBMCs QRT-PCR IRF8 28492552 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Cell Death Dis Acute promyelocytic leukemia progenitors cell C-kit+ apl progenitors RT-PCR Irs 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Downregulation Int J Biochem Cell Biol - - Western blot Irs 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Downregulation Int J Biochem Cell Biol Myoblast cell C2C12 Western blot IRS1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis IRS1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR IRTA2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ITGA2 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ITGAM 19468689 Leukemia Homo sapiens Inhibit - - Upregulation Invest New Drugs Acute promyelocytic leukemia cell NB4 Flow cytometry ITGAM 15755292 Leukemia Homo sapiens Inhibit - - Upregulation Br J Haematol Acute promyelocytic leukemia cell NB4 Flow cytometry ITGAM 15625759 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell APL Flow cytometry ITGAM 25130808 Leukemia Homo sapiens Inhibit 12-o-tetradecanoylphorbol-13-acetate synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Flow cytometry ITGAM 18055984 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Haematologica Acute promyelocytic leukemia cell NB4 IFA ITGAM 22331136 Leukemia Homo sapiens Inhibit Tetramethylpyrazine synergy Upregulation Braz J Med Biol Res Acute promyelocytic leukemia cell HL-60 Kit ITGB1 12852829 Leukemia Homo sapiens Inhibit - - Downregulation Acta Pharmacol Sin Acute promyelocytic leukemia cell NB4 RT-PCR ITGB2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ITGB3 20470221 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Lymphoma Chronic myelogenous leukemia cell K-562 Western blot ITIH1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ITM2B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Itpr1 24831965 Neuronal-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR Itpr1 27638049 Development-toxicity Mus musculus Induce - - Phosphorylation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot Itpr1 27461142 Immune-toxicity Mus musculus Induce - - Phosphorylation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 Western blot ITPR1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis JAB1 18076791 Liver-cancer Homo sapiens Inhibit - - Downregulation Ai Zheng Hepatocellular carcinoma cell SMMC-7721 Western blot JAG2 23497375 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Cell Int Myeloma cell RPMI 8226 QRT-PCR, Western blot JAK1 19951532 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Western blot JAK1 17121903 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res Embryonic kidney cell HEK-293 Western blot JAK2 26781180 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation Mol Med Rep Hepatocellular carcinoma cell MHCC97H Western blot JAK2 11721366 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot JAK3 24762999 Leukemia Homo sapiens Inhibit 5-aza-2'-deoxycytidine synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 QRT-PCR JLK1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR JLK1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR JMJD1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis jnk 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Environ Pollut - - Western blot Jnk 23363563 Heart-toxicity Rattus norvegicus Induce Genistein synergy Phosphorylation Cell Physiol Biochem - - Western blot Jnk 23363563 Heart-toxicity Rattus norvegicus Induce Genistein synergy Phosphorylation Cell Physiol Biochem Neonatal ventricular cell NRVCs Western blot Jnk 31734849 Bone-toxicity Rattus norvegicus Induce - - Phosphorylation Arch Toxicol - - Western blot Jnk 31319442 Lung-toxicity Rattus norvegicus Induce - - Upregulation J Appl Toxicol - - Western blot Jnk 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Phosphorylation Cell Physiol Biochem Heart myoblast H9C2 Western blot Jnk 19141569 Liver-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Ind Health Hepatocyte Hepatocytes Western blot Jnk 27174766 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Appl Pharmacol Brain microglia cell HAPI Western blot Jnk 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation,Phosphorylation Molecules Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Jnk 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation,Phosphorylation Molecules - - Western blot Jnk 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Phosphorylation Toxicol Lett Heart myoblast H9C2 Western blot JNK 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Downregulation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot JNK 31734849 Bone-toxicity Homo sapiens Induce - - Phosphorylation Arch Toxicol Articular chondrocyte cell HC-a Western blot JNK 29048129 Myeloma Homo sapiens Inhibit - - Phosphorylation Br J Haematol Myeloma cell MM.1S Western blot JNK 28789348 Bone-cancer Homo sapiens Inhibit Doxorubicin synergy Phosphorylation,Downregulation Oncol Lett Osteosarcoma cell MG-63 Western blot JNK 28446277 Leukemia Homo sapiens Inhibit - - Dephosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot JNK 21946058 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Anticancer Drugs Ewing's sarcoma cell A-673 Western blot JNK 21946058 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Anticancer Drugs Ewing's sarcoma cell RD-ES Western blot JNK 21847655 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation Apoptosis Cervical adenocarcinoma cell HeLa Western blot JNK 21846841 Tongue-cancer Homo sapiens Inhibit - - Upregulation J Pharmacol Exp Ther Oral squamous cell carcinoma cell Tca-8113 Western blot JNK 21741957 Leukemia Homo sapiens Inhibit Irradiation synergy Phosphorylation Chem Biol Interact Acute promyelocytic leukemia cell HL-60 Western blot JNK 21655183 Ovary-cancer Homo sapiens Inhibit Ly294002 synergy Phosphorylation PLoS One Ovarian cancer cell COC1 Western blot JNK 20799280 Mesothelioma Homo sapiens Inhibit - - Phosphorylation J Cell Physiol Mesothelioma cell NCI-H2052 Western blot JNK 20724260 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Can J Neurol Sci Glioma cell U251MG Western blot JNK 20724260 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Can J Neurol Sci Glioblastoma cell T98G Western blot JNK 20534739 Leukemia Homo sapiens Inhibit - - Phosphorylation Clin Cancer Res B cell chronic lymphocytic leukemia cell B-CLL Western blot JNK 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation,Phosphorylation Leuk Res Myeloma cell RPMI 8226 Western blot JNK 18937079 Liver-cancer Homo sapiens Inhibit Wortmannin synergy Upregulation,Phosphorylation Med Oncol Hepatocellular carcinoma cell HEPG2 Western blot JNK 18728151 Lymphoma Homo sapiens Inhibit - - Phosphorylation J Leukoc Biol Lung adenocarcinoma cell A549 Western blot JNK 18636201 Lung-cancer Homo sapiens Inhibit Sulindac synergy Phosphorylation Oncol Rep Lung cancer cell NCI-H157 Western blot JNK 18566239 Leukemia Homo sapiens Inhibit - - Downregulation Mol Cancer Ther Acute promyelocytic leukemia cell NB4 Western blot JNK 18281123 Lung-cancer Homo sapiens Inhibit Sulindac synergy Phosphorylation Lung Cancer Lung cancer cell NCI-H1299 Western blot JNK 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Phosphorylation Mol Cell Endocrinol Breast cancer cell MDA-MB-231 Western blot JNK 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot JNK 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot JNK 17331470 Leukemia Homo sapiens Inhibit - - Phosphorylation Biochem Biophys Res Commun Acute promyelocytic leukemia cell NB4 Western blot JNK 17331470 Leukemia Homo sapiens Inhibit - - Phosphorylation Biochem Biophys Res Commun Chronic myelogenous leukemia cell K-562 Western blot JNK 17237268 Leukemia Homo sapiens Inhibit Phytosphingosine synergy Dephosphorylation Mol Cancer Ther Histiocytic lymphoma cell U-937 Western blot JNK 17182041 Leukemia Homo sapiens Inhibit - - Phosphorylation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot JNK 17145888 Lymphoma Homo sapiens Inhibit - - Upregulation Cancer Res Leukemia cell Jurkat Western blot JNK 16930595 Bone-cancer Homo sapiens Inhibit - - Phosphorylation FEBS Lett Ewing's sarcoma cell CADO-ES Western blot JNK 16818652 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Leukemia cell KT1 Western blot JNK 16818652 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Acute promyelocytic leukemia cell NB4 Western blot JNK 16733740 Leukemia Homo sapiens Inhibit - - Upregulation Ann Hematol Acute promyelocytic leukemia cell NB4 Western blot JNK 16646077 Bone-cancer Homo sapiens Inhibit - - Phosphorylation Int J Cancer Ewing's sarcoma cell EW7 Western blot JNK 16646077 Bone-cancer Homo sapiens Inhibit - - Phosphorylation Int J Cancer Neuroblastoma cell SK-N-MC Western blot JNK 16328441 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Lung adenocarcinoma cell H1355 Western blot JNK 29409467 Gastric-cancer Homo sapiens Inhibit - - Upregulation,Phosphorylation BMC Cancer Gastric adenocarcinoma cell AGS Western blot JNK 16283431 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation J Biomed Sci Epidermoid carcinoma cell A-431 Western blot JNK 15961274 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Cell Signal Epidermoid carcinoma cell A-431 Western blot JNK 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Testis carcinoma cell F9 Western blot JNK 15231573 Leukemia Homo sapiens Inhibit - - Phosphorylation Blood Burkitt's lymphoma cell Raji Western blot JNK 14610070 Leukemia Homo sapiens Inhibit 12-o-tetradecanoylphorbol-13-acetate synergy Phosphorylation J Biol Chem Histiocytic lymphoma cell U-937 Western blot JNK 12931215 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute myeloid leukemia cell NKM-1 Western blot JNK 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Upregulation Mol Cancer Ther Renal cell adenocarcinoma cell A-498 Western blot JNK 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Upregulation Mol Cancer Ther Renal cell carcinoma cell UOK121N Western blot JNK 12754411 Liver-cancer Homo sapiens Inhibit - - Phosphorylation Exp Mol Med Hepatocellular carcinoma cell HEPG2 Western blot JNK 12480548 Kidney-cancer Homo sapiens Inhibit - - Phosphorylation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot JNK 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Phosphorylation Cancer Lett Osteosarcoma cell HOS Western blot JNK 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Phosphorylation Cancer Lett Fibrosarcoma cell HT1080 Western blot JNK 24944602 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Exp Ther Med Acute monocytic leukemia cell THP-1 Western blot JNK 24428916 Leukemia Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation,Phosphorylation BMC Cancer Acute promyelocytic leukemia cell HL-60 Western blot JNK 24273890 Leukemia Homo sapiens Inhibit Vitamin-K2 synergy Upregulation,Phosphorylation Pharmazie Acute promyelocytic leukemia cell HL-60 Western blot JNK 23688753 Leukemia Homo sapiens Inhibit - - Phosphorylation Zhonghua Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot JPH2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis JUN 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis JUN 24956101 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation PLoS One Chronic lymphocytic leukemia cell CLL cell RT-PCR, Western blot JUN 28446277 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot JUN 22719067 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Cancer Res Histiocytic lymphoma cell U-937 Western blot JUN 21655183 Ovary-cancer Homo sapiens Inhibit Ly294002 synergy Phosphorylation PLoS One Ovarian cancer cell COC1 Western blot JUN 18822310 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Epidermoid carcinoma cell A-431 Western blot JUN 18633430 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot JUN 18566239 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Acute promyelocytic leukemia cell NB4 Western blot JUN 18210215 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation,Phosphorylation J Biomed Sci Epidermoid carcinoma cell A-431 Western blot JUN 17332940 Myeloma Homo sapiens Inhibit - - Phosphorylation Int J Oncol Myeloma cell U266 Western blot JUN 17182041 Leukemia Homo sapiens Inhibit - - Phosphorylation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot JUN 15466933 Leukemia Homo sapiens Inhibit Trolox synergy Phosphorylation Blood Acute promyelocytic leukemia cell NB4 Western blot JUN 11454688 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Cancer Res Prostate carcinoma cell PC-3 Western blot JUN 25174355 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Int J Oncol Lung adenocarcinoma cell H23 Western blot JUN 25174355 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Int J Oncol Non-small cell lung cancer cell H358 Western blot JUN 25174355 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot JUN 25174355 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Int J Oncol Lung adenocarcinoma cell H1975 Western blot JUN 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Upregulation,Phosphorylation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 Western blot JUNB 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis JUNB 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis JWA 18387645 Cervical-cancer Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa Western blot JWA 18387645 Breast-cancer Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Breast cancer cell MCF7 Western blot JWA 17336041 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cell Signal Cervical adenocarcinoma cell HeLa Western blot KALPHA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KARCA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KCNA5 15213294 Leukemia Homo sapiens Inhibit - - Upregulation Mol Pharmacol Embryonic kidney cell HEK-293 Western blot KCNG1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Kcnh2 25107562 Heart-toxicity Homo sapiens Induce Resveratrol detoxicity Downregulation Naunyn Schmiedebergs Arch Pharmacol Embryonic kidney cell HEK-293 Western blot KCNH2 31218953 Colorectal-cancer Homo sapiens Inhibit Resveratrol synergy Downregulation Curr Pharm Des Colorectal carcinoma cell HCT116 Western blot KCNH2 25107562 Heart-toxicity Homo sapiens Induce Resveratrol detoxicity Downregulation Naunyn Schmiedebergs Arch Pharmacol Embryonic kidney cell HEK-293 Western blot Kcnj2 22889704 Heart-toxicity Cavia porcellus Induce - - Downregulation Int J Cardiol - - Western blot Kcnj2 22853924 Heart-toxicity Rattus norvegicus Induce - - Downregulation Cardiovasc Res Neonatal cardiac fibroblast Cardiac fibroblasts Western blot KCNK12 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KCNMA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Kcnq1 29339628 Heart-toxicity Mus musculus Induce - - Downregulation Cell Physiol Biochem - - QRT-PCR, Western blot Kcnq1 29339628 Heart-toxicity Mus musculus Induce - - Downregulation Cell Physiol Biochem Primary neonatal mouse cardiomyocyte Primarycultured neonatal mouse cardiomyocyte QRT-PCR, Western blot KCTD12 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis KCTD6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KCTD9 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Kdr 18161919 Gastric-cancer Mus musculus Inhibit - - Downregulation World J Gastroenterol Gastric adenocarcinoma cell SGC-7901 IFA keap1 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot Keap1 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Environ Pollut - - QRT-PCR Keap1 27335833 Liver-toxicity Mus musculus Induce - - Downregulation ISRN Hepatol - - RT-PCR, Western blot KEAP1 19279006 Myeloma Homo sapiens Inhibit - - Downregulation J Biol Chem Multiple myeloma cell KMS-11 Western blot KI67 19673332 Gastric-cancer Homo sapiens Inhibit - - Downregulation Zhongguo Zhong Xi Yi Jie He Za Zhi Gastric adenocarcinoma cell SGC-7901 IHC KI67 27212442 Pancreas-cancer Homo sapiens Inhibit Px-478 synergy Downregulation Cancer Lett Pancreatic cancer cell PANC-1 IHC KI67 30600718 Leukemia Homo sapiens Inhibit - - Upregulation Artif Cells Nanomed Biotechnol Acute promyelocytic leukemia cell NB4 QRT-PCR KI67 27318970 Liver-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Hepatocellular carcinoma cell HEPG2 QRT-PCR, Western blot KIAA0052 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA0261 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA0368 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA0599 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA0650 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA0669 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA1363 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA1522 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA1598 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA1613 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIAA1919 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIF13B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIF27 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis KIF3A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KIT 24908354 Leukemia Homo sapiens Inhibit Deferoxamine synergy Downregulation Leuk Res Acute promyelocytic leukemia cell HL-60 IHC, IFA KIT 23815908 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR KIT 19950550 Lymphoma Homo sapiens Inhibit - - Phosphorylation,Downregulation Zhonghua Zhong Liu Za Zhi Lymphoma cell T2 Western blot KIT 19619438 Lymphoma Homo sapiens Inhibit - - Phosphorylation,Downregulation Ai Zheng Lymphoma cell T2 Western blot KITLG 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KLC2L 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KLF13 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KLF3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KLF5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Klf9 27561292 Liver-toxicity Rattus norvegicus Induce Allicin detoxicity Downregulation Biol Trace Elem Res - - Western blot KLHDC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KNTC2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis KRAS 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR KRT13 19489262 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Kou Qiang Yi Xue Za Zhi Oral epithelioid carcinoma cell KB IFA KSHV 21068240 Skin-cancer Homo sapiens Inhibit - - Upregulation J Virol Kaposi's sarcoma cell KS QRT-PCR, Flow cytometry KSHV 21068240 Lymphoma Homo sapiens Inhibit - - Upregulation J Virol Primary effusion lymphoma cell PEL QRT-PCR, Flow cytometry L225R 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR LAMA3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LAMP1 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR, Western blot LAMP1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot LAMP1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot LAMP2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot LAMP2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot LAMP2 25081691 Lymphoma Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Burkitt's lymphoma cell Raji Western blot LANA1 24250827 Lymphoma Homo sapiens Inhibit Interferon-alpha synergy Downregulation PLoS One Lymphoma cell BC-3 Western blot LANB1 26469751 Eye-cancer Oryctolagus cuniculus Inhibit - - Downregulation Invest Ophthalmol Vis Sci Primary TenonĄ¯s capsule fibroblast rTFs Western blot LAPTM5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LATS2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LBR 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis LCN1 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis LCN2 19763917 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR Ldh 19888912 Heart-toxicity Cavia porcellus Induce Vitamin-C detoxicity Upregulation J Environ Pathol Toxicol Oncol - - Kit Ldh 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Upregulation Biomed Pharmacother Heart myoblast H9C2 Kit LDH 29314450 Neuronal-toxicity Homo sapiens Induce Ellagic-acid detoxicity Upregulation J Biochem Mol Toxicol Neuroblastoma cell SH-SY5Y Kit LDHA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LDHA 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute monocytic leukemia cell THP-1 QRT-PCR LDHA 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR LDHA 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR LDLRAD1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis LDOC1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Let-7a 28980872 Breast-cancer Homo sapiens Inhibit - - Upregulation Cell Cycle Breast cancer cell MCF7 QRT-PCR Let-7a 28980872 Breast-cancer Homo sapiens Inhibit - - Upregulation Cell Cycle Breast cancer cell SK-BR-3 QRT-PCR Let-7a 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7a 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR Let-7b 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7b 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR Let-7c 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7c 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR Let-7d 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7d 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR Let-7d 24356076 Leukemia Homo sapiens Inhibit - - Downregulation Cell Physiol Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7d 24356076 Leukemia Homo sapiens Inhibit - - Downregulation Cell Physiol Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR Let-7e 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7e 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR Let-7f 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7f 26118712 Brain-cancer Homo sapiens Inhibit - - Upregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR Let-7g 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7g 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR Let-7i 22072212 Leukemia Homo sapiens Inhibit - - Upregulation Tumour Biol Acute promyelocytic leukemia cell NB4 QRT-PCR Let-7i 26118712 Brain-cancer Homo sapiens Inhibit - - Downregulation Anticancer Agents Med Chem Glioma cell U87 QRT-PCR LFNG 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LGALS1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LGALS3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LGALS3 25254965 Breast-cancer Homo sapiens Inhibit - - Upregulation PLoS One Breast cancer cell MDA-MB-231 Western blot LGALS8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LGI3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LGUL 19996132 Liver-cancer Homo sapiens Inhibit - - Upregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling LIF 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LIM 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LIN7C 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LIVIN 21867610 Leukemia Homo sapiens Inhibit Bortezomib synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Leukemia cell Jurkat RT-PCR LKB1 23041229 Leukemia Homo sapiens Inhibit 2-deoxy-d-glucose synergy Downregulation Biochem Pharmacol Acute promyelocytic leukemia cell HL-60 Western blot LKB1 25506699 Leukemia Homo sapiens Inhibit Etomoxir synergy Upregulation PLoS One Acute promyelocytic leukemia cell HL-60 Western blot LMNA 25983101 Esophageal-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Esophageal squamous carcinoma cell ECA109 RT-PCR,QRT-PCR, Western blot LMNA 25983101 Gastric-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Gastric adenocarcinoma cell SGC-7901 RT-PCR,QRT-PCR, Western blot LMNA 25983101 Pancreas-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Pancreatic cancer cell BxPC-3 RT-PCR,QRT-PCR, Western blot LMNA 25983101 Colorectal-cancer Homo sapiens Inhibit Pd98059 synergy Upregulation Tumori Colorectal cancer cell LS 174 RT-PCR,QRT-PCR, Western blot LMOD1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LMP1 16648906 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Braz J Med Biol Res Nasopharyngeal carcinoma cell HNE1-LMP1 IFA, Western blot LMP1 15141597 Leukemia Homo sapiens Inhibit - - Downregulation Natl Med J India Nasopharyngeal carcinoma cell CSNE-1 IHC LMP1 21605886 Lung-cancer Homo sapiens Inhibit - - Upregulation Virology Lung adenocarcinoma cell A549 QRT-PCR, Western blot LMP1 21605886 Lung-cancer Homo sapiens Inhibit - - Upregulation Virology Nasopharyngeal carcinoma cell NPC QRT-PCR, Western blot LMP1 16724694 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Tumori Nasopharyngeal carcinoma cell HNE1-LMP1 RT-PCR, Western blot LMX1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis lncRNA Kcnq1ot1 29339628 Heart-toxicity Mus musculus Induce - - Downregulation Cell Physiol Biochem - - QRT-PCR lncRNA Kcnq1ot1 29339628 Heart-toxicity Mus musculus Induce - - Downregulation Cell Physiol Biochem Primary neonatal mouse cardiomyocyte Primarycultured neonatal mouse cardiomyocyte QRT-PCR lncRNA OTUD6B-AS1 32952848 Bladder-cancer Homo sapiens Inhibit - - Upregulation Oxid Med Cell Longev Bladder carcinoma cell T24 QRT-PCR lncRNA ROR 32017938 Liver-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Hepatocellular carcinoma cell HEPG2 QRT-PCR LOC148206 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LOC286016 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LOC387680 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LOC389119 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LOC51333 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LOC55971 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LOX 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell MDA-MB-231 QRT-PCR LOX 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell SUM-159 QRT-PCR LPL 25187411 Anemia Homo sapiens Inhibit - - Downregulation Acta Biochim Biophys Sin (Shanghai) Bone marrow cell BM QRT-PCR LPL 25543494 Anemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Bone marrow mononuclear cell BMMCs RT-PCR LRP 26692822 Liver-cancer Homo sapiens Inhibit 5-fluorouracil synergy Downregulation Cancer Cell Int Hepatocellular carcinoma cell HEPG2 QRT-PCR, Western blot LRP 14703445 Lung-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Jie He He Hu Xi Za Zhi Lung adenocarcinoma cell A549 Western blot LRP4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LRRC8B 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LRRFIP1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis LRRFIP1 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis LRRK1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LSD1 25815518 Myeloma Homo sapiens Inhibit Valproic Acid synergy Upregulation Mol Med Rep Myeloma cell RPMI 8226 RT-PCR, Western blot LSM11 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LTA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis LTB4DH 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ltbr 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis LTC4S 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis luteinizing hormone 18630931 Reproductive-toxicity Mus musculus Induce - - Downregulation Chem Res Toxicol - - ELISA LYN 30213730 Leukemia Homo sapiens Inhibit - - Phosphorylation,Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot LYN 26540567 Leukemia Homo sapiens Inhibit - - Phosphorylation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot MAC30 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MAD1L1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis MAD2 29950208 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot MAD2 18668508 Bladder-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Tumorigenic cell CGL-4 Western blot MAD2 18668508 Bladder-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Bladder urothelial carcinoma cell BFTC905 Western blot MAD2 18668508 Bladder-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Bladder transitional carcinoma cell NTUB1 Western blot MAD2 18668508 Ovary-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Ovarian cancer cell OVCAR-3 Western blot MAML1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MAN1A2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MAP1B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis map1lc3a 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Environ Pollut - - Western blot Map1lc3a 31605998 Development-toxicity Mus musculus Induce NaF detoxicity Downregulation Chemosphere - - IFA Map1lc3a 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Map1lc3a 31846860 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf Spermatogonial cell GC-1 QRT-PCR Map1lc3a 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR Map1lc3a 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Upregulation PPAR Res - - QRT-PCR,Western blot Map1lc3a 30225639 Neuronal-toxicity Mus musculus Induce - - Upregulation Arch Toxicol - - QRT-PCR,Western blot Map1lc3a 30225639 Neuronal-toxicity Mus musculus Induce - - Upregulation Arch Toxicol - - QRT-PCR,Western blot Map1lc3a 33352257 Liver-toxicity Mus musculus Induce 3-MA detoxicity Upregulation In Vitro Normal hepatocyte AML12 QRT-PCR, Western blot Map1lc3a 33352257 Liver-toxicity Mus musculus Induce Rapamycin detoxicity Upregulation In Vitro Normal hepatocyte AML12 QRT-PCR, Western blot Map1lc3a 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot Map1lc3a 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot Map1lc3a 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot Map1lc3a 32044640 Reproductive-toxicity Mus musculus Induce Rapamycin detoxicity Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 QRT-PCR, Western blot Map1lc3a 32044640 Reproductive-toxicity Mus musculus Induce 3-MA detoxicity Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 Western blot Map1lc3a 31605998 Development-toxicity Mus musculus Induce NaF detoxicity Upregulation Chemosphere - - Western blot Map1lc3a 29111283 Pancreas-toxicity Mus musculus Induce - - Upregulation Food Chem Toxicol - - Western blot Map1lc3a 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Upregulation Int J Biochem Cell Biol - - Western blot Map1lc3a 28849506 Neuronal-toxicity Mus musculus Induce Taurine detoxicity Upregulation Adv Exp Med Biol - - Western blot Map1lc3a 27291853 Liver-toxicity Rattus norvegicus Induce Taurine detoxicity Upregulation Sci Rep - - Western blot Map1lc3a 26775255 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Upregulation Biochimie - - Western blot Map1lc3a 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biomed Pharmacother - - Western blot Map1lc3a 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biomed Pharmacother Insulin-secreting cell INS-1 Western blot Map1lc3a 25144547 Leukemia Rattus norvegicus Inhibit Resveratrol-(rev)or synergy Upregulation PLoS One Neonatal left ventricular myocyte Neonatal rat left ventricular myocytes Western blot MAP1LC3A 20302512 Brain-cancer Homo sapiens Inhibit - - Upregulation Biol Chem Glioma cell U87 IHC MAP1LC3A 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR MAP1LC3A 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR MAP1LC3A 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR MAP1LC3A 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR MAP1LC3A 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR MAP1LC3A 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR MAP1LC3A 20574048 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Blood Acute promyelocytic leukemia cell NB4 QRT-PCR MAP1LC3A 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot MAP1LC3A 31205465 Rheumatoid-arthritis Homo sapiens Inhibit Vitamin-D synergy Upregulation PPAR Res Fibroblast-like synoviocyte fibroblast-like synoviocytes QRT-PCR,Western blot MAP1LC3A 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot MAP1LC3A 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot MAP1LC3A 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot MAP1LC3A 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot MAP1LC3A 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot MAP1LC3A 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot MAP1LC3A 25241256 Lymphoma Homo sapiens Inhibit - - Upregulation Biochimie Burkitt's lymphoma cell P3HR-1 QRT-PCR, Western blot MAP1LC3A 22519831 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Mech Methods Chronic myelogenous leukemia cell K-562 RT-PCR MAP1LC3A 22519831 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Mech Methods Chronic myelogenous leukemia cell K-562 RT-PCR MAP1LC3A 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Endocr Relat Cancer Ovarian cancer cell SK-OV-3 Western blot MAP1LC3A 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation Cancers (Basel) Cervical carcinoma cell Ca Ski Western blot MAP1LC3A 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation Cancers (Basel) Cervix squamous cell carcinoma cell SiHa Western blot MAP1LC3A 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 Western blot MAP1LC3A 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot MAP1LC3A 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot MAP1LC3A 28612524 Liver-cancer Homo sapiens Inhibit - - Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Western blot MAP1LC3A 22898604 Leukemia Homo sapiens Inhibit - - Upregulation Blood Chronic myelogenous leukemia cell K-562 Western blot MAP1LC3A 22884570 Leukemia Homo sapiens Inhibit - - Upregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot MAP1LC3A 22884570 Lymphoma Homo sapiens Inhibit - - Upregulation FEBS Lett Leukemia cell Jurkat Western blot MAP1LC3A 22884570 Breast-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Breast cancer cell MCF7 Western blot MAP1LC3A 22884570 Gastric-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Gastric cancer cell MGC-803 Western blot MAP1LC3A 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell LNCaP Western blot MAP1LC3A 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell PC-3 Western blot MAP1LC3A 21971985 Leukemia Homo sapiens Inhibit - - Upregulation Int J Mol Med Acute promyelocytic leukemia cell HL-60 Western blot MAP1LC3A 21971985 Leukemia Homo sapiens Inhibit - - Upregulation Int J Mol Med Chronic myelogenous leukemia cell K-562 Western blot MAP1LC3A 20699661 Ovary-cancer Homo sapiens Inhibit - - Upregulation Autophagy Ovarian cancer cell Human ovarian cancer cell Western blot MAP1LC3A 20656687 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Leukemia cell KT1 Western blot MAP1LC3A 20574048 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot MAP1LC3A 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Upregulation Autophagy Fibrosarcoma cell HT1080 Western blot MAP1LC3A 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/GGT Western blot MAP1LC3A 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/BASAL Western blot MAP1LC3A 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell PC-3 Western blot MAP1LC3A 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell LNCaP Western blot MAP1LC3A 27291853 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Sci Rep Hepatocellular carcinoma cell HEPG2 Western blot MAP1LC3A 26629016 Leukemia Homo sapiens Inhibit Hyperoside synergy Upregulation Int J Clin Exp Med Acute promyelocytic leukemia cell HL-60 Western blot MAP1LC3A 30677399 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Chem Biol Interact Hepatic stellate cell LX-2 Western blot MAP1LC3A 30341298 Liver-cancer Homo sapiens Inhibit - - Upregulation Nat Commun Hepatocellular carcinoma cell HEPG2 Western blot MAP1LC3A 30237564 Lung-cancer Homo sapiens Inhibit - - Upregulation Cell Death Dis Lung adenocarcinoma cell NCI-H1975 Western blot MAP1LC3A 30237538 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Cell Death Dis Hepatocellular carcinoma cell HEPG2 Western blot MAP1LC3A 29434902 Leukemia Homo sapiens Inhibit Chloroquine synergy Upregulation Oncol Lett Acute promyelocytic leukemia cell NB4 Western blot MAP1LC3A 25721868 Brain-cancer Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Glioma cell U87 Western blot MAP1LC3A 25721868 Brain-cancer Homo sapiens Inhibit - - Upregulation Cell Physiol Biochem Glioma cell U251 Western blot MAP1LC3A 25577250 Bone-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot MAP1LC3A 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Osteosarcoma cell HOS Western blot MAP1LC3A 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Upregulation Cancer Lett Fibrosarcoma cell HT1080 Western blot MAP1LC3A 25446377 Lymphoma Homo sapiens Inhibit MG132 synergy Downregulation Eur J Cancer Burkitt's lymphoma cell Raji Western blot MAP1LC3A 25144547 Leukemia Homo sapiens Inhibit Resveratrol-(rev)or synergy Upregulation PLoS One Acute promyelocytic leukemia cell NB4 Western blot MAP1LC3A 25110043 Lymphoma Homo sapiens Inhibit - - Upregulation Oncol Rep Burkitt's lymphoma cell Raji Western blot MAP1LC3A 25081691 Lymphoma Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Burkitt's lymphoma cell Raji Western blot MAP1LC3A 24496081 Leukemia Homo sapiens Inhibit Resveratrol synergy Upregulation Cancer Biol Ther Chronic myelogenous leukemia cell K-562 Western blot MAP1LC3A 24496081 Leukemia Homo sapiens Inhibit Resveratrol synergy Upregulation Cancer Biol Ther Histiocytic lymphoma cell U-937 Western blot MAP1LC3A 23621864 Ovary-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ovarian cancer cell HEY Western blot MAP1LC3B 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR MAP1LC3B 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR MAP1LC3B 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR MAP4K3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MAPK 30646589 Breast-cancer Homo sapiens Inhibit - - Upregulation Genes (Basel) Breast cancer cell MCF7 Kit MAPK 25758096 Leukemia Homo sapiens Inhibit Rapamycin synergy Phosphorylation Int J Hematol Acute promyelocytic leukemia cell HL-60 Western blot MAPK 25758096 Leukemia Homo sapiens Inhibit Rapamycin synergy Downregulation Int J Hematol Histiocytic lymphoma cell U-937 Western blot MAPK 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Phosphorylation Cancer Lett Osteosarcoma cell HOS Western blot MAPK 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Phosphorylation,Downregulation Cancer Lett Fibrosarcoma cell HT1080 Western blot Mapk1 23542815 Heart-toxicity Cavia porcellus Induce - - Phosphorylation Toxicol Lett Cardiac fibroblast Cardiac fibroblasts Western blot Mapk1 23542815 Heart-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Lett Neonatal cardiac fibroblast NRCF Western blot Mapk1 15761769 Lymphoma Mus musculus Inhibit - - Phosphorylation Cancer Chemother Pharmacol B cell lymphoma cell LY-ar Western blot Mapk1 15761769 Lymphoma Mus musculus Inhibit - - Phosphorylation Cancer Chemother Pharmacol B cell lymphoma cell LY-as Western blot MAPK1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MAPK1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR MAPK1 11304686 Leukemia Homo sapiens Inhibit - - Dephosphorylation Int J Cancer Histiocytic lymphoma cell U-937 Western blot MAPK12 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Upregulation J Hematol Oncol Intrahepatic cholangiocarcinoma cell CCLP-1 Western blot MAPK12 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Upregulation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot MAPK15 28467781 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Oncotarget Embryonic kidney cell HEK 293T Western blot MAPK3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Mapk8 22488045 Immune-toxicity Mus musculus Induce - - Upregulation,Phosphorylation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot MAPK8 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Phosphorylation Int J Oncol Liver cancer cell BEL-7402 Western blot MAPK8 20724260 Brain-cancer Homo sapiens Inhibit - - Downregulation Can J Neurol Sci Glioma cell U251MG Western blot MAPK8 20724260 Brain-cancer Homo sapiens Inhibit - - Downregulation Can J Neurol Sci Glioblastoma cell T98G Western blot MAPK8 18412143 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation J Cell Physiol Cervical adenocarcinoma cell HeLa Western blot MAPK8 29581752 Liver-cancer Homo sapiens Inhibit Megestrol-acetate synergy Upregulation,Phosphorylation Exp Ther Med Liver cancer cell BEL-7402 Western blot MAPK8 14701702 Leukemia Homo sapiens Inhibit - - Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot MAPK8 12296996 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biochem Mol Biol Chronic myelogenous leukemia cell K-562 Western blot MAPK8 11454688 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Cancer Res Prostate carcinoma cell PC-3 Western blot MAPK8IP1 18566239 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Acute promyelocytic leukemia cell NB4 Western blot MAPKAPK2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MAPRE1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MARCHF3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MARCHF4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MATN1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MAX 26046465 Liver-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Embryo hepatocyte L-O2 QRT-PCR MBD4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MC1R 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MC2R 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MCA3 19996132 Liver-cancer Homo sapiens Inhibit - - Upregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling MCL 19549371 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji QRT-PCR Mcl1 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis Mcl1 18349030 Skin-cancer Mus musculus Inhibit - - Downregulation Ann Oncol Sezary Syndrome cell HuT 78 Western blot Mcl1 18349030 Skin-cancer Mus musculus Inhibit - - Downregulation Ann Oncol Cutaneous t-cell lymphoma cell MyLa 2059 Western blot MCL1 21473291 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Res Burkitt's lymphoma cell Raji Kit,QRT-PCR MCL1 21473291 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Res Burkitt's lymphoma cell NAMALWA Kit,QRT-PCR MCL1 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR MCL1 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation Cancers (Basel) Cervical carcinoma cell Ca Ski Western blot MCL1 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation Cancers (Basel) Cervix squamous cell carcinoma cell SiHa Western blot MCL1 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell MM.1S Western blot MCL1 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell RPMI 8226-S Western blot MCL1 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Downregulation J Int Med Res Gastric adenocarcinoma cell SGC-7901 Western blot MCL1 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation J Int Med Res Gastric adenocarcinoma cell SGC-7901 Western blot MCL1 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Downregulation J Int Med Res Gastric cancer cell MGC-803 Western blot MCL1 22971477 Gastric-cancer Homo sapiens Inhibit ABT-737 synergy Upregulation J Int Med Res Gastric cancer cell MGC-803 Western blot MCL1 20723298 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Mantle cell lymphoma cell MCL Western blot MCL1 19364129 Myeloma Homo sapiens Inhibit - - Downregulation J Proteome Res Myeloma cell U266 Western blot MCL1 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell U266 Western blot MCL1 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell RPMI 8226 Western blot MCL1 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell MM.1S Western blot MCL1 18354037 Myeloma Homo sapiens Inhibit - - Downregulation Blood Multiple myeloma cell KMS-11 Western blot MCL1 28024471 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Histiocytic lymphoma cell U-937 Western blot MCL1 19771260 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Treat Colorectal adenocarcinoma cell HT-29 Western blot MCL1 30763586 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Upregulation,Phosphorylation Exp Cell Res Acute promyelocytic leukemia cell HL-60 Western blot MCL1 30763586 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Upregulation,Phosphorylation Exp Cell Res Histiocytic lymphoma cell U-937 Western blot MCL1 30763586 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Upregulation Exp Cell Res Primary acute promyelocytic leukemia cell Primary AML cell Western blot MCL1 30763586 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Upregulation Exp Cell Res Acute promyelocytic leukemia cell HL-60 Western blot MCL1 30213730 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot MCL1 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot MCL1 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Mol Cancer Ther Primary leukemia cell PRIMARY FLT3-ITD AML Western blot MCL1 16115949 Lymphoma Homo sapiens Inhibit (-)-Epigallocatechin-3-gallate synergy Upregulation Clin Cancer Res Burkitt's lymphoma cell HS-Sultan Western blot MCL1 12883267 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Pancreas Pancreatic cancer cell MIA PaCa-2 Western blot MCL1 12492118 Myeloma Homo sapiens Inhibit - - Downregulation Mol Cancer Ther Myeloma cell U266 Western blot MCL1 26540567 Leukemia Homo sapiens Inhibit - - Downregulation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot MCL1 25982179 Leukemia Homo sapiens Inhibit Dichloroacetate synergy Downregulation Leuk Res Primary acute promyelocytic leukemia cell Primary APL cell Western blot MCL1 25869069 Leukemia Homo sapiens Inhibit Fludarabine synergy Dephosphorylation Biochem Biophys Res Commun Chronic lymphocytic leukemia cell CLL cell Western blot MCL1 25758096 Leukemia Homo sapiens Inhibit Rapamycin synergy Downregulation Int J Hematol Histiocytic lymphoma cell U-937 Western blot MCL1 25485499 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cell Cycle Pancreatic cancer cell MIA PaCa-2 Western blot MCL1 25485499 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cell Cycle Prostate carcinoma cell DU 145 Western blot MCL1 25485499 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cell Cycle Osteosarcoma cell U-2 OS Western blot MCL1 24956101 Leukemia Homo sapiens Inhibit - - Downregulation PLoS One Leukemia cell MEC-1 Western blot MCL1 24428916 Leukemia Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation,Phosphorylation BMC Cancer Acute promyelocytic leukemia cell HL-60 Western blot MCM2 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR MCM3 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR MCM4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MCM4 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR MCM5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MCM5 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR MCM6 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR MCM7 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Liver cancer cell Huh7.5.1 QRT-PCR,Western blot MCM7 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR,Western blot MCM7 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell Hep3B Western blot MCM7 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell primary HCC cells Western blot MCOLN3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Mcp1 22488045 Immune-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR MCTS1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MCY 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell LNCaP QRT-PCR MCY 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell PC-3 QRT-PCR Mda 28849506 Neuronal-toxicity Mus musculus Induce Taurine detoxicity Upregulation Adv Exp Med Biol - - Kit Mda 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Environ Pollut - - QRT-PCR MDA 29214213 Liver-cancer Homo sapiens Inhibit - - Upregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Kit MDA 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - Kit MDA 24107457 Neuronal-toxicity Felis catus Induce Resveratrol detoxicity Upregulation Hum Exp Toxicol - - Kit MDM2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MDM2 19513507 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Hepatocellular carcinoma cell HEPG2 Western blot MDM2 19513507 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot MDM2 25485499 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Prostate carcinoma cell DU 145 Western blot MDM4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MDR1 25435954 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Lett Chronic myelogenous leukemia cell K-562 QRT-PCR MDR1 25435954 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Lett Primary mononuclear cell Primary mononuclear cell QRT-PCR MDR1 22959511 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot MDR1 22959511 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot MDR1 18072624 Leukemia Homo sapiens Inhibit Buthionine-sulfoximine synergy Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR MDR1 15979894 Leukemia Homo sapiens Inhibit - - Downregulation Pharmacol Res Chronic myelogenous leukemia cell K-562 RT-PCR MDR65 27840903 Brain-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Neuroblastoma cell SKNSH Western blot MDR65 15982806 Liver-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Hepatocellular carcinoma cell HEPG2 Western blot MDS1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ME1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ME1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ME2 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis Mecp2 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR MEF2C 28492552 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Cell Death Dis Acute promyelocytic leukemia progenitors cell C-kit+ apl progenitors RT-PCR MEG3 31003765 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HCCLM3 QRT-PCR MEG3 31003765 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell SMMC-7721 QRT-PCR MEIS1 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Oncotarget Acute myeloid leukemia cell MOLM14 QRT-PCR MEIS1 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Oncotarget Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR MEIS1 28492552 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Cell Death Dis Acute promyelocytic leukemia progenitors cell C-kit+ apl progenitors RT-PCR Mek 28454374 Skin-cancer Mus musculus Inhibit - - Dephosphorylation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell Western blot Mek 28454374 Skin-cancer Mus musculus Inhibit - - Dephosphorylation Oncol Lett Melanoma cell B16 Western blot Mek 11585900 Leukemia Cercopithecus aethiops Inhibit - - Upregulation Mol Cell Biol Kidney fibroblast CV-1 Western blot MEK 22751450 Leukemia Homo sapiens Inhibit - - Dephosphorylation Leukemia Acute promyelocytic leukemia cell NB4 Western blot MEK 20592496 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Biol Ther Osteosarcoma cell HOS Western blot MEK 20592496 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Cancer Biol Ther Osteosarcoma cell MNNG Western blot MEK 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Dephosphorylation Mol Cell Endocrinol Breast cancer cell SK-BR-3 Western blot MEK 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Dephosphorylation Mol Cell Endocrinol Breast cancer cell MDA-MB-231 Western blot MEK 17336041 Cervical-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation Cell Signal Cervical adenocarcinoma cell HeLa Western blot MEK1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR MEK1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR MEK1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR MEK1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR MEK2 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR MEK2 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR MEP1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MEP50 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MER11 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot, IFA MERTK 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MET 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MET 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis Mfn1 29867492 Heart-toxicity Mus musculus Induce Salvianolic-acid-a detoxicity Upregulation Front Pharmacol - - Western blot MFN1 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot MFN1 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Chemosphere - - QRT-PCR,Western blot MFN1 30516227 Kidney-toxicity Gallus gallus Induce - - Downregulation Metallomics - - QRT-PCR,Western blot MFN1 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot MFN1 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot MFN1 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR, Western blot Mfn2 29867492 Heart-toxicity Mus musculus Induce Salvianolic-acid-a detoxicity Upregulation Front Pharmacol - - Western blot MFN2 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR MFN2 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR MFN2 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot MFN2 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Chemosphere - - QRT-PCR,Western blot MFN2 30516227 Kidney-toxicity Gallus gallus Induce - - Downregulation Metallomics - - QRT-PCR,Western blot MFN2 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot MFRN2 25256833 Brain-cancer Homo sapiens Inhibit - - Upregulation Eur J Med Res Glioblastoma cell U-87 MG QRT-PCR, Western blot MFRN2 25256833 Brain-cancer Homo sapiens Inhibit - - Upregulation Eur J Med Res Glioblastoma cell T98G QRT-PCR, Western blot MGC14560 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MGC15407 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MGC2574 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MGP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Mhc 20299303 Skin-toxicity Mus musculus Induce - - Upregulation Environ Health Perspect Myoblast cell C2C12 Western blot MHC2TA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MIG6 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MIP1 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay MKK3 16818652 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Leukemia cell KT1 Western blot MKK3 16818652 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Acute promyelocytic leukemia cell NB4 Western blot MKK3 11454688 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Cancer Res Prostate carcinoma cell PC-3 Western blot MKNK1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MKNK1 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot MKNK1 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot MKNK1 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Histiocytic lymphoma cell U-937 Western blot MKNK2 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot MKNK2 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot MKNK2 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Histiocytic lymphoma cell U-937 Western blot MKRN2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MLAA-34 29059232 Lymphoma Homo sapiens Inhibit - - Downregulation PLoS One Histiocytic lymphoma cell U-937 Western blot MLC 17182041 Leukemia Homo sapiens Inhibit - - Phosphorylation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot Mlck 32683294 Lung-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - Western blot MLCK 32683294 Lung-toxicity Homo sapiens Induce Pd98059 detoxicity Upregulation Toxicol Lett Normal lung epithelial cell BEAS-2B QRT-PCR MLLT10 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MLLT11 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis MMD 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MMP1 23253724 Skin-toxicity Homo sapiens Induce - - Downregulation Chin Med J (Engl) Skin fibroblast HSFB ELISA, RT-PCR MMP10 22178533 Ovary-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharm Sci Ovarian cancer cell OVCAR-3 QRT-PCR Mmp13 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Downregulation PPAR Res - - ELISA Mmp13 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol CD4+T cell CD4+T cell ELISA Mmp13 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - QRT-PCR MMP13 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a QRT-PCR MMP14 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR MMP16 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Mmp2 27671604 Heart-toxicity Rattus norvegicus Induce - - Upregulation Sci Rep - - QRT-PCR Mmp2 26407229 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Toxicol Pharmacol Primary cortical neuron cell Primary rat cortical neuron RT-PCR Mmp2 19822495 Liver-cancer Mus musculus Inhibit - - Downregulation Hepatobiliary Pancreat Dis Int Liver cancer cell H22 Western blot Mmp2 18294404 Brain-cancer Rattus norvegicus Inhibit Berberine synergy Downregulation BMC Cancer Glioma cell C6 Western blot MMP2 23253724 Skin-toxicity Homo sapiens Induce - - Downregulation Chin Med J (Engl) Skin fibroblast HSFB ELISA, RT-PCR, Gelatin zymography assay MMP2 17650671 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Kit MMP2 24680928 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H Kit MMP2 25728215 Cervical-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Cervix squamous cell carcinoma cell SiHa Kit, Western blot MMP2 15962302 Fibrosarcoma Homo sapiens Inhibit - - Downregulation J Cell Biochem Fibrosarcoma cell HT1080 Northern blot,luciferase, Western blot MMP2 21969006 Brain-cancer Homo sapiens Inhibit Silibinin synergy Upregulation Neurochem Res Glioblastoma cell U-87 MG QRT-PCR MMP2 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR MMP2 24680928 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H QRT-PCR MMP2 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR MMP2 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR, Gelatin zymography MMP2 23232515 Liver-cancer Homo sapiens Inhibit - - Downregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Hepatocellular carcinoma cell SMMC-7721 QRT-PCR, Western blot MMP2 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovarian cancer cell 3AO RT-PCR, ELISA MMP2 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovary adenocarcinoma cell SW 626 RT-PCR, ELISA MMP2 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovarian cancer cell HO-8910PM RT-PCR, ELISA MMP2 25537191 Skin-cancer Homo sapiens Induce - - Upregulation Arch Toxicol Keratinocyte HACAT RT-PCR, Western blot MMP2 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung adenocarcinoma cell A549 Western blot MMP2 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Small cell lung cancer cell NCI-H446 Western blot MMP2 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Human umbilical vein endothelial cells HUVECs Western blot MMP2 18294404 Brain-cancer Homo sapiens Inhibit Berberine synergy Downregulation BMC Cancer Glioma cell U87 Western blot MMP2 17512576 Cervical-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Cervical adenocarcinoma cell HeLa Western blot MMP2 17512576 Cervical-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Cervix squamous cell carcinoma cell SiHa Western blot MMP2 26781180 Liver-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Hepatocellular carcinoma cell MHCC97H Western blot MMP2 29138840 Liver-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Hepatocellular carcinoma cell HEPG2 Western blot, IHC Mmp3 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Downregulation PPAR Res - - ELISA MMP3 28956730 Lung-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Normal lung epithelial cell BEAS-2B Western blot MMP3 25010681 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Colorectal adenocarcinoma cell HT-29 Western blot MMP7 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Lymphoma cell JeKo-1 QRT-PCR MMP7 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell Mino QRT-PCR MMP7 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell SP53 QRT-PCR MMP7 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell LNCaP QRT-PCR MMP7 26966376 Prostate-cancer Homo sapiens Inhibit - - Downregulation Onco Targets Ther Prostate carcinoma cell PC-3 QRT-PCR Mmp9 23210436 Asthma Mus musculus Inhibit - - Upregulation Can J Physiol Pharmacol - - IHC Mmp9 27671604 Heart-toxicity Rattus norvegicus Induce - - Upregulation Sci Rep - - QRT-PCR Mmp9 26407229 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Toxicol Pharmacol Primary cortical neuron cell Primary rat cortical neuron RT-PCR MMP9 23253724 Skin-toxicity Homo sapiens Induce - - Downregulation Chin Med J (Engl) Acute monocytic leukemia cell THP-1 ELISA, RT-PCR, Gelatin zymography assay MMP9 17650671 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Kit MMP9 24680928 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H Kit MMP9 15962302 Fibrosarcoma Homo sapiens Inhibit - - Downregulation J Cell Biochem Fibrosarcoma cell HT1080 Northern blot,luciferase, Western blot MMP9 21969006 Brain-cancer Homo sapiens Inhibit Silibinin synergy Downregulation Neurochem Res Glioblastoma cell U-87 MG QRT-PCR MMP9 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR MMP9 24680928 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H QRT-PCR MMP9 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR MMP9 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR, Gelatin zymography MMP9 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovarian cancer cell 3AO RT-PCR, ELISA MMP9 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovary adenocarcinoma cell SW 626 RT-PCR, ELISA MMP9 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovarian cancer cell HO-8910PM RT-PCR, ELISA MMP9 24956101 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Chronic lymphocytic leukemia cell CLL cell RT-PCR, Flow cytometry MMP9 16648906 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Braz J Med Biol Res Nasopharyngeal carcinoma cell HNE1-LMP1 RT-PCR, Western blot MMP9 25537191 Skin-cancer Homo sapiens Induce - - Upregulation Arch Toxicol Keratinocyte HACAT RT-PCR, Western blot MMP9 28956730 Lung-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Normal lung epithelial cell BEAS-2B Western blot MMP9 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung adenocarcinoma cell A549 Western blot MMP9 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Small cell lung cancer cell NCI-H446 Western blot MMP9 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Human umbilical vein endothelial cells HUVECs Western blot MMP9 21773820 Liver-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Hepatocellular carcinoma cell HCCLM3 Western blot MMP9 20592496 Bone-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Osteosarcoma cell HOS Western blot MMP9 20592496 Bone-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Osteosarcoma cell MNNG Western blot MMP9 30477221 Gastric-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Gastric cancer cell MGC-803 Western blot MMP9 30477221 Gastric-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Gastric adenocarcinoma cell SGC-7901 Western blot MMP9 25728215 Cervical-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Cervix squamous cell carcinoma cell SiHa Western blot MMP9 25010681 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Colorectal adenocarcinoma cell HT-29 Western blot MMP9 29138840 Liver-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Hepatocellular carcinoma cell HEPG2 Western blot, IHC MNT 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MOCOS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MOE 16920938 Immune-toxicity Homo sapiens Induce - - Phosphorylation J Immunol Peripheral blood mononuclear cell PBMC Western blot MPP5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MPP6 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis MRD1 24928535 Ovary-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Ovarian cancer cell SK-OV-3 QRT-PCR MRP 15634520 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Zhong Liu Za Zhi Acute promyelocytic leukemia cell MR-2 IHC MRP 14703445 Lung-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Jie He He Hu Xi Za Zhi Lung adenocarcinoma cell A549 Western blot MRP1 31355259 Liver-toxicity Homo sapiens Induce Proanthocyanidins detoxicity Downregulation Biomed Res Int Embryo hepatocyte L-O2 ELISA MRP1 27736728 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot MRP1 27736728 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot MRP1 27736728 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR,Western blot MRP1 26692822 Liver-cancer Homo sapiens Inhibit 5-fluorouracil synergy Downregulation Cancer Cell Int Hepatocellular carcinoma cell HEPG2 QRT-PCR, Western blot MRP1 23052202 Leukemia Homo sapiens Inhibit - - Upregulation Arch Toxicol Acute promyelocytic leukemia cell HL-60 Western blot MRP2 27736728 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot MRP2 27736728 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 QRT-PCR,Western blot MRP63 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MRPL24 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MRPL30 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MRPL42 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MRPS29 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling MRPS30 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MRPS30 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling MS4A6A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MSH2 15494640 Bladder-cancer Homo sapiens Inhibit - - Upregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 Western blot MSK1 16762916 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Leukemia cell KT1 Western blot MSK1 16762916 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot MSL3L1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis MSR1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Msra 31473893 Liver-toxicity Mus musculus Induce - - Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot MSRA 31442540 Liver-toxicity Gallus gallus Induce - - Downregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR MSRA 31442540 Liver-toxicity Gallus gallus Induce - - Upregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes Western blot Msrb1 31473893 Liver-toxicity Mus musculus Induce - - Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot MSRB1 31442540 Liver-toxicity Gallus gallus Induce - - Downregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR MSRB1 31442540 Liver-toxicity Gallus gallus Induce - - Upregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes Western blot Msrb2 31473893 Liver-toxicity Mus musculus Induce - - Upregulation Biol Trace Elem Res - - QRT-PCR MT1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Myeloma cell U266 RT-PCR MT1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Myeloma cell RPMI 8226 RT-PCR MT1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Myeloma cell MM.1S RT-PCR MT1MMP 15962302 Fibrosarcoma Homo sapiens Inhibit - - Downregulation J Cell Biochem Fibrosarcoma cell HT1080 Northern blot,luciferase, Western blot MT1X 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Liver cancer cell Huh7.5.1 QRT-PCR MT1X 31186405 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Death Dis Hepatocellular carcinoma cell SMMC-7721 QRT-PCR MT2A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MT2A 15725085 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell OPM2 Western blot MTA1 12478894 Ovary-cancer Homo sapiens Inhibit - - Downregulation Ai Zheng Ovarian cancer cell 3AO Flow cytometry MTA1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MTCH2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot MTCH2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot MTCH2 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot Mtert 22693909 Breast-cancer Mus musculus Inhibit - - Downregulation Zhongguo Zhong Yao Za Zhi Breast cancer cell MA-891 RT-PCR MTF1 32952848 Bladder-cancer Homo sapiens Inhibit - - Upregulation Oxid Med Cell Longev Bladder carcinoma cell T24 Western blot MTHFD1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MTMR2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MTOP 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Downregulation,Dephosphorylation PLoS One Prostate carcinoma cell LNCaP Western blot MTOP 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Dephosphorylation Tumour Biol Liver cancer cell Huh7 Western blot mtor 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Environ Pollut - - Western blot Mtor 33352257 Liver-toxicity Mus musculus Induce - - Downregulation In Vitro Normal hepatocyte AML12 QRT-PCR Mtor 31326754 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - QRT-PCR Mtor 31605998 Development-toxicity Mus musculus Induce NaF detoxicity Downregulation Chemosphere - - QRT-PCR,Western blot Mtor 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Downregulation,Dephosphorylation PPAR Res - - QRT-PCR,Western blot Mtor 32781346 Reproductive-toxicity Mus musculus Induce - - Downregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot Mtor 20299303 Skin-toxicity Mus musculus Induce - - Phosphorylation,Downregulation Environ Health Perspect Myoblast cell C2C12 Western blot Mtor 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - Western blot Mtor 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - Western blot MTOR 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR MTOR 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR MTOR 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR MTOR 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR MTOR 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot MTOR 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Phosphorylation,Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot MTOR 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - Western blot MTOR 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Dephosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot MTOR 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Phosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell HCCC-9810 Western blot MTOR 22751450 Leukemia Homo sapiens Inhibit - - Dephosphorylation Leukemia Acute promyelocytic leukemia cell NB4 Western blot MTOR 20137118 Leukemia Homo sapiens Inhibit Ly294002 synergy Upregulation,Phosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot MTOR 20137118 Leukemia Homo sapiens Inhibit Rapamycin synergy Upregulation,Phosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot MTOR 25577250 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Tumour Biol Chondrosarcoma cell SW 1353 Western blot MTOR 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Dephosphorylation Cancer Lett Osteosarcoma cell HOS Western blot MTOR 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Downregulation,Dephosphorylation Cancer Lett Fibrosarcoma cell HT1080 Western blot MTOR 24969414 Gastric-cancer Homo sapiens Inhibit - - Downregulation,Dephosphorylation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot MTOR 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Dephosphorylation Pharmazie Acute promyelocytic leukemia cell HL-60 Western blot MTOR 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Dephosphorylation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot MTORC 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR MTORC 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR, Western blot MTORC 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR, Western blot MTX1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Murf1 32184170 Muscle-toxicity Mus musculus Induce - - Upregulation Toxicol In Vitro Myoblast cell C2C12 Western blot MVD 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR MXD1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis MYBL1 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis MYC 12478894 Ovary-cancer Homo sapiens Inhibit - - Downregulation Ai Zheng Ovarian cancer cell 3AO Flow cytometry MYC 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis MYC 19408305 Leukemia Homo sapiens Inhibit - - Downregulation Int J Cancer Acute promyelocytic leukemia cell NB4 RT-PCR MYC 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H446 QRT-PCR MYC 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-209(CSCs) QRT-PCR MYC 28533173 Leukemia Homo sapiens Inhibit - - Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR MYC 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR MYC 23255470 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Carcinog Lung epithelial cell NULI-1 QRT-PCR MYC 22944098 Leukemia Homo sapiens Inhibit - - Downregulation Hematology Acute promyelocytic leukemia cell NB4 QRT-PCR MYC 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR MYC 29574283 Leukemia Homo sapiens Inhibit Vs-5584 synergy Downregulation Biomed Pharmacother Acute lymphoblastic leukemia cell NALM6 QRT-PCR MYC 26046465 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Embryo hepatocyte L-O2 QRT-PCR MYC 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical adenocarcinoma cell HeLa QRT-PCR MYC 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell Ca Ski QRT-PCR MYC 25117446 Cervical-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Cervical carcinoma cell C4-I QRT-PCR MYC 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell HSR-GBM1 QRT-PCR MYC 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR MYC 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40821 QRT-PCR MYC 24161621 Brain-cancer Homo sapiens Inhibit U0126 synergy Upregulation Neurochem Int Neuroblastoma cell SK-N-BE(2) QRT-PCR MYC 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Upregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR MYC 23293885 Leukemia Homo sapiens Inhibit BIBR1532 synergy Downregulation Anticancer Agents Med Chem Acute promyelocytic leukemia cell NB4 QRT-PCR MYC 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot MYC 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H209 QRT-PCR, Western blot MYC 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR, Western blot MYC 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Large cell lung cancer cell NCI-H460 QRT-PCR, Western blot MYC 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot MYC 25436934 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Lett Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot MYC 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Lymphoma cell Kappas299 QRT-PCR, Western blot MYC 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot MYC 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell Jurkat QRT-PCR, Western blot MYC 18726487 Cervical-cancer Homo sapiens Inhibit - - Downregulation Sci China C Life Sci Cervical adenocarcinoma cell HeLa RT-PCR MYC 12903512 Cervical-cancer Homo sapiens Inhibit - - Downregulation Zhongguo Yi Xue Ke Xue Yuan Xue Bao Cervical adenocarcinoma cell HeLa RT-PCR MYC 12903497 Esophageal-cancer Homo sapiens Inhibit - - Downregulation Zhongguo Yi Xue Ke Xue Yuan Xue Bao Esophageal squamous carcinoma cell ECA109 RT-PCR MYC 11775218 Cervical-cancer Homo sapiens Inhibit - - Downregulation Chin Med J (Engl) Cervix squamous cell carcinoma cell SiHa RT-PCR MYC 17706770 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Res Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot MYC 12903512 Lung-cancer Homo sapiens Inhibit - - Downregulation Zhongguo Yi Xue Ke Xue Yuan Xue Bao Lung adenocarcinoma cell GLC-82 RT-PCR, Western blot MYC 12903512 Gastric-cancer Homo sapiens Inhibit - - Downregulation Zhongguo Yi Xue Ke Xue Yuan Xue Bao Gastric adenocarcinoma cell SGC-7901 RT-PCR, Western blot MYC 29059232 Cervical-cancer Homo sapiens Inhibit - - Downregulation PLoS One Cervical adenocarcinoma cell HeLa Western blot MYC 29059232 Lymphoma Homo sapiens Inhibit - - Downregulation PLoS One Histiocytic lymphoma cell U-937 Western blot MYC 29048129 Myeloma Homo sapiens Inhibit - - Downregulation Br J Haematol Myeloma cell MM.1S Western blot MYC 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Lymphoma cell JeKo-1 Western blot MYC 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell Mino Western blot MYC 28901456 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Mantle cell lymphoma cell SP53 Western blot MYC 28565807 Leukemia Homo sapiens Inhibit - - Downregulation Exp Ther Med Leukemia cell Jurkat Western blot MYC 22093145 Breast-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Breast epithelial carcinoma cell T-47D Western blot MYC 20953137 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Myeloma cell OPM2 Western blot MYC 20953137 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot MYC 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell HL-60 Western blot MYC 27010069 Leukemia Homo sapiens Inhibit - - Downregulation Sci Rep Acute promyelocytic leukemia cell NB4 Western blot MYC 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell 5-8F Western blot MYC 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell CNE-2 Western blot MYC 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngealcarcinoma cell 5-8F Western blot MYC 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngeal carcinoma cell CNE-2 Western blot MYC 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Lett Chronic myelogenous leukemia cell K-562 Western blot MYC 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Lett Chronic myeloid leukemia cell MEG-A2 Western blot MYC 15494640 Bladder-cancer Homo sapiens Inhibit - - Downregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 Western blot MYC 11775218 Cervical-cancer Homo sapiens Inhibit - - Downregulation Chin Med J (Engl) Cervix squamous cell carcinoma cell SiHa Western blot MYC 26510911 Brain-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Glioma stem cell T387 Western blot MYC 26510911 Brain-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Glioma stem cell T4121 Western blot MYC 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot MYC 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot MYC 24276018 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Med (Berl) Glioma cell SFxL Western blot MYC 24276018 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Med (Berl) Glioblastoma cell LN-229 Western blot MYC 24276018 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Med (Berl) Glioblastoma cell T98G Western blot MYC 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell SMMC-7721 Western blot MYC 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell HEPG2 Western blot MYCBP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MYCN 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MYD88 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR MYH10 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MYH14 25258189 Bone-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis MYH6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MYH7 28094846 Heart-toxicity Homo sapiens Induce - - Downregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Microarray analysis MYL4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MYO1G 28466809 Leukemia Homo sapiens Inhibit - - Downregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS Myogenin 20299303 Skin-toxicity Mus musculus Induce - - Downregulation Environ Health Perspect - - Western blot MYST4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis MYT1L 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis N223d 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR NAB2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NACA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NAGLU 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot NAGLU 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot NAMPT 28501332 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Toxicol Appl Pharmacol Tongue squamous cell carcinoma cell SCC-15 RT-PCR, IFA Nanog 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR,Western blot NANOG 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Front Oncol Head and neck squamous cell carcinoma cell SAS HN-CICs Western blot NANOG 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Front Oncol Head and neck squamous cell carcinoma cell SAS-CisPt R Western blot NANOG 27965050 Leukemia Homo sapiens Inhibit - - Downregulation J Ethnopharmacol Chronic myelogenous leukemia cell K-562 Western blot NANOG 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell 5-8F Western blot NANOG 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell CNE-2 Western blot NANOG 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngealcarcinoma cell 5-8F Western blot NANOG 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngeal carcinoma cell CNE-2 Western blot NAP1L1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NAP1L4 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis NB3 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis NCF1 16330433 Leukemia Homo sapiens Inhibit - - Upregulation Haematologica Acute promyelocytic leukemia cell NB4 QRT-PCR NCKAP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NCOA4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ncx 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget - - Western blot Ncx 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Upregulation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot NDRG1 21575456 Cervical-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Zhong Liu Za Zhi Cervical adenocarcinoma cell HeLa RT-PCR, Western blot NDST1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NDUFA4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ndufs8 24831965 Neuronal-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR,Western blot NEAT2 30913205 Lung-cancer Homo sapiens Inhibit - - Downregulation Med Sci Monit Human umbilical vein endothelial cells HUVECs QRT-PCR, Western blot NEDD1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Nek1 24337744 Immune-toxicity Mus musculus Induce - - Downregulation J Immunol Leukemia cell RAW 264.7 Western blot Nek1 24337744 Immune-toxicity Mus musculus Induce - - Downregulation J Immunol Fibroblast L929 Western blot Nek3 24337744 Immune-toxicity Mus musculus Induce - - Downregulation J Immunol Leukemia cell RAW 264.7 Western blot Nek3 24337744 Immune-toxicity Mus musculus Induce - - Downregulation J Immunol Fibroblast L929 Western blot NEMO 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR NEMO 27039805 Brain-cancer Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR NESTIN 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Tumour Biol Glioblastoma cell U-87 MG IFA NESTIN 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Tumour Biol Likely glioblastoma cell U-87 MG IFA NESTIN 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioma cell U251MG Western blot NESTIN 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG Western blot NETO2 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis NEUGRIN 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NEUROFILAMENT 19060284 Retinoblastoma Homo sapiens Inhibit - - Upregulation Invest Ophthalmol Vis Sci Retinoblastoma cell SNUOT-Rb1 Western blot NF2 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis NFE2L2 30317545 Skin-toxicity Homo sapiens Induce - - Nuclear translocation,Upregulation J Cell Physiol Primary skin fibroblast Primary skin fibroblast IFA, Western blot NFE2L2 25344162 Vascular-toxicity Homo sapiens Induce - - Upregulation Mutat Res Genet Toxicol Environ Mutagen Bronchial epithelial cell HBE Western blot NFE2L3 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR NFE2L3 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR nfkb 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Fish Shellfish Immunol - - Western blot Nfkb 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Downregulation Biol Trace Elem Res Heart myoblast H9C2 ELISA Nfkb 25413961 Lung-cancer Mus musculus Inhibit - - Downregulation Cell Biochem Biophys Lung cancer cell LEWIS EMSA Nfkb 31258454 Development-toxicity Rattus norvegicus Induce - - Upregulation Dose Response - - QRT-PCR Nfkb 27561292 Liver-toxicity Rattus norvegicus Induce Allicin detoxicity Upregulation Biol Trace Elem Res - - Western blot NfkB 28115242 Gastrointestinal-toxicity Homo sapiens Induce - - Upregulation Toxicology Colorectal adenocarcinoma cell HT-29 Western blot NFKB 22944098 Leukemia Homo sapiens Inhibit - - Dephosphorylation Hematology Acute promyelocytic leukemia cell NB4 ELISA NFKB 27039805 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG ELISA NFKB 15494640 Bladder-cancer Homo sapiens Inhibit - - Downregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 EMSA NFKB 12676792 Lymphoma Homo sapiens Inhibit - - Downregulation Blood Hodgkin lymphoma cell L540CY EMSA NFKB 12676792 Lymphoma Homo sapiens Inhibit - - Downregulation Blood Hodgkin lymphoma cell HD-MYZ EMSA NFKB 17959082 Gastric-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Nei Ke Za Zhi Gastric adenocarcinoma cell SGC-7901 EMSA,IHC NFKB 25415199 Leukemia Homo sapiens Inhibit - - Downregulation PLoS One Myelodysplastic syndrome cell MUTZ-1 Gel shift assay NFKB 25415199 Leukemia Homo sapiens Inhibit - - Downregulation PLoS One Myelodysplastic syndrome cell SKM-1 Gel shift assay NFKB 21781490 Leukemia Homo sapiens Inhibit Deferoxamine synergy Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 IHC NFKB 15962302 Fibrosarcoma Homo sapiens Inhibit - - Downregulation J Cell Biochem Fibrosarcoma cell HT1080 Luciferase NFKB 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot NFKB 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot NFKB 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot NFKB 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot NFKB 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot NFKB 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot NFKB 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot NFKB 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot NFKB 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR, Western blot NFKB 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot NFKB 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot NFKB 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot NFKB 25436934 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Lett Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot NFKB 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell MDA-MB-231 RT-PCR, Western blot NFKB 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell MCF7 RT-PCR, Western blot NFKB 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell SK-BR-3 RT-PCR, Western blot NFKB 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Downregulation PLoS One Acute promyelocytic leukemia cell NB4 RT-PCR, Western blot NFKB 24738333 Lymphoma Homo sapiens Inhibit Doxorubicin synergy Downregulation J Biomed Nanotechnol Burkitt's lymphoma cell Raji RT-PCR, Western blot NFKB 23257433 Leukemia Homo sapiens Inhibit Bortezomib synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 SP IHC NFKB 31550857 Brain-cancer Homo sapiens Inhibit - - Downregulation Zhonghua Zhong Liu Za Zhi Neuroblastoma cell SKNSH Western blot NFKB 18575716 Colorectal-cancer Homo sapiens Inhibit Sulindac synergy Upregulation Oncol Rep Colorectal carcinoma cell HCT116 Western blot NFKB 30333888 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Lett Burkitt's lymphoma cell Raji Western blot NFKB 30333888 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Lett Leukemia cell Jurkat Western blot NFKB 16105982 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute myeloid leukemia cell ML1 Western blot NFKB 16105982 Leukemia Homo sapiens Inhibit - - Downregulation Blood Bone marrow mononuclear cell BONE MARROW MONONUCLEAR CELL Western blot NFKB 15547942 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 Western blot NFKB 15476326 Leukemia Homo sapiens Inhibit - - Upregulation Zhejiang Da Xue Xue Bao Yi Xue Ban Chronic myelogenous leukemia cell K-562 Western blot NFKB 26524030 Lymphoma Homo sapiens Inhibit Adriamycin synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji Western blot NFKB 24337533 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Rep Chronic myelogenous leukemia cell K-562 Western blot NFKB 29274627 Lung-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 Western blot, IFA Nfkb1 28756814 Kidney-toxicity Mus musculus Induce Grape-seed-procyanidin-extract detoxicity Upregulation Biomed Environ Sci - - QRT-PCR,Western blot NFKB1 18922898 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Cancer Res Colorectal adenocarcinoma cell SW480 EMSA NFKB1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NFKB1 20889596 Rheumatoid-arthritis Homo sapiens Inhibit - - Downregulation J Rheumatol Fibroblast-like synoviocyte fibroblast-like synoviocytes RT-PCR,Kit NFKB1 23387208 Lung-cancer Homo sapiens Inhibit - - Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Lung adenocarcinoma cell A549 RT-PCR, Western blot NFKB1 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - Western blot NFKB1 31632492 Leukemia Homo sapiens Inhibit Resveratrol synergy Downregulation J Cancer Chronic myelogenous leukemia cell K-562 Western blot NFKB1 16517539 Brain-cancer Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot NFKBIA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NFKBIA 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR NFKBIA 15547942 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 Western blot NFKBIA 11424005 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Hematol J Lymphoma cell HuT 102 Western blot NHE1 27039805 Brain-cancer Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR NKG2D 18463537 Leukemia Homo sapiens Inhibit - - Upregulation J Immunother Acute promyelocytic leukemia cell NB4 RT-PCR, Flow cytometry NKG2D 18463537 Leukemia Homo sapiens Inhibit - - Upregulation J Immunother Chronic myelogenous leukemia cell K-562 RT-PCR, Flow cytometry NKG2D 18463537 Breast-cancer Homo sapiens Inhibit - - Upregulation J Immunother Breast cancer cell MCF7 RT-PCR, Flow cytometry NLGN1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NLRP3 30237538 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Cell Death Dis Hepatocellular carcinoma cell HEPG2 Western blot NM23 12452020 Ovary-cancer Homo sapiens Inhibit - - Upregulation Ai Zheng Ovarian cancer cell 3AO Flow cytometry Nme1 19822495 Liver-cancer Mus musculus Inhibit - - Upregulation Hepatobiliary Pancreat Dis Int Liver cancer cell H22 Western blot NME1 12478894 Ovary-cancer Homo sapiens Inhibit - - Upregulation Ai Zheng Ovarian cancer cell 3AO Flow cytometry NME7 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis NMES1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NMP1 27795556 Lymphoma Homo sapiens Inhibit - - Downregulation Leukemia Lymphoma cell DEL Western blot NMP1 27795556 Lymphoma Homo sapiens Inhibit - - Downregulation Leukemia Lymphoma cell SU-DHL-1 Western blot NMP1 27795556 Lymphoma Homo sapiens Inhibit - - Downregulation Leukemia Lymphoma cell SUP-M2 Western blot NMT1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NMT2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NOL6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NOLC1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NOS2A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NOS3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NOTCH 29738779 Liver-cancer Homo sapiens Inhibit - - Upregulation Life Sci Hepatocellular carcinoma cell HEP3B QRT-PCR NOTCH 29738779 Liver-toxicity Homo sapiens Induce - - Downregulation Life Sci Liver cell Chang liver cell QRT-PCR NOTCH 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR NOTCH 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell HSR-GBM1 QRT-PCR NOTCH 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR NOTCH 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40821 QRT-PCR NOTCH1 23497375 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Cell Int Myeloma cell RPMI 8226 QRT-PCR, Western blot NOTCH1 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Cancer stem-like cell GBM neurospheres RT-PCR NOTCH1 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG RT-PCR NOTCH1 22978106 Breast-cancer Homo sapiens Inhibit - - Downregulation Zhongguo Zhong Xi Yi Jie He Za Zhi Breast cancer cell SK-BR-3 RT-PCR, Western blot NOTCH1 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell MDA-MB-231 RT-PCR, Western blot NOTCH1 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell MCF7 RT-PCR, Western blot NOTCH1 22949821 Breast-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Breast cancer cell SK-BR-3 RT-PCR, Western blot NOTCH1 25088040 Lung-cancer Homo sapiens Inhibit - - Upregulation Curr Cancer Drug Targets Human umbilical vein endothelial cells HUVECs RT-PCR, Western blot NOTCH1 31093499 Lung-cancer Homo sapiens Inhibit - - Downregulation Biomed Res Int Human umbilical vein endothelial cells HUVECs Western blot NOTCH1 31093499 Lung-cancer Homo sapiens Inhibit - - Downregulation Biomed Res Int Small cell lung cancer cell NCI-H69 Western blot NOTCH1 28980872 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Breast cancer cell MCF7 Western blot NOTCH1 28980872 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Breast cancer cell SK-BR-3 Western blot NOTCH1 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Human umbilical vein endothelial cells HUVECs Western blot NOTCH1 19962820 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioblastoma cell U-87 MG Western blot NOTCH1 19962820 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell U251MG Western blot NOTCH1 19962820 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell U373MG Western blot NOTCH1 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Lung adenocarcinoma cell A549 Western blot NOTCH1 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Large cell lung cancer cell NCI-H460 Western blot NOTCH1 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Small cell lung cancer cell NCI-H446 Western blot NOTCH2 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Cancer stem-like cell GBM neurospheres RT-PCR NOTCH2 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG RT-PCR NOTCH3 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Cancer stem-like cell GBM neurospheres RT-PCR NOTCH3 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG RT-PCR NOTCH4 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Cancer stem-like cell GBM neurospheres RT-PCR NOTCH4 23542114 Brain-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Glioblastoma cell U-87 MG RT-PCR NOVA1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NOX4 24762191 Pulmonary-fibrosis Homo sapiens Inhibit - - Downregulation Respir Res Normal human lung fibroblast NHLFs QRT-PCR NOXA 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Upregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR NOXA 27521572 Sarcoma Homo sapiens Inhibit Vincristine synergy Upregulation Cancer Lett Rhabdomyosarcoma cell RD QRT-PCR,Western blot NOXA 27521572 Sarcoma Homo sapiens Inhibit Vincristine synergy Upregulation Cancer Lett Alveolar hrabdomyosarcomas cell RH-30 QRT-PCR,Western blot NOXA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell U266 Western blot NOXA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell RPMI 8226 Western blot NOXA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell MM.1S Western blot NOXA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Multiple myeloma cell KMS-11 Western blot NOXA 26540567 Leukemia Homo sapiens Inhibit - - Upregulation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot NOXA 24956101 Leukemia Homo sapiens Inhibit - - Downregulation PLoS One Leukemia cell MEC-1 Western blot NOXA 24884809 Liver-cancer Homo sapiens Inhibit Nutlin-3 synergy Upregulation Mol Cancer Hepatocellular carcinoma cell HEPG2 Western blot NOXA 24884809 Liver-cancer Homo sapiens Inhibit Nutlin-3 synergy Upregulation Mol Cancer Hepatocellular carcinoma cell SMMC-7721 Western blot NPD014 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NPHS2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NPM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NPPB 28094846 Heart-toxicity Homo sapiens Induce - - Downregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Microarray analysis NPY 11027660 Brain-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Neuroblastoma cell SK-N-BE(2) Northern blot NPY6R 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis nqo1 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - Western blot Nqo1 29049341 Immune-toxicity Mus musculus Induce - - Upregulation PLoS One Splenocyte Splenocytes QRT-PCR Nqo1 25966753 Reproductive-toxicity Mus musculus Induce Grape-seed-proanthocyanidin detoxicity Upregulation Biomed Environ Sci - - QRT-PCR Nqo1 26187899 Reproductive-toxicity Mus musculus Induce Lutein detoxicity Upregulation Hum Exp Toxicol - - RT-PCR Nqo1 27608960 Heart-toxicity Rattus norvegicus Induce Imperatorin detoxicity Upregulation,Downregulation Toxicol In Vitro Heart myoblast H9C2 RT-PCR, Western blot Nqo1 27608960 Heart-toxicity Rattus norvegicus Induce Sec-o-glucosylhamaudol detoxicity Upregulation,Downregulation Toxicol In Vitro Heart myoblast H9C2 RT-PCR, Western blot Nqo1 27561292 Liver-toxicity Rattus norvegicus Induce Allicin detoxicity Downregulation Biol Trace Elem Res - - Western blot NQO1 30257321 Bladder-cancer Homo sapiens Inhibit Bacillus calmette-guerin synergy Upregulation Biomed Pharmacother Bladder carcinoma cell 5637 QRT-PCR,Western blot NQO1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Myeloma cell RPMI 8226 RT-PCR, Western blot NQO1 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Multiple myeloma cell KMS-11 RT-PCR, Western blot NQO1 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot NQO1 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute monocytic leukemia cell THP-1 RT-PCR, Western blot NQO1 29260515 Lung-cancer Homo sapiens Inhibit - - Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Lung adenocarcinoma cell A549 Western blot NQO1 19417148 Myeloma Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Multiple myeloma cell KMS-11 Western blot NQO1 29876539 Mammary-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation ACS Omega Breast epithelial cell MCF 10A Western blot NQO1 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute promyelocytic leukemia cell NB4 Western blot NQO1 23285138 Myeloma Homo sapiens Inhibit - - Upregulation PLoS One Myeloma cell RPMI 8226 Western blot NQO1 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Oral squamous cell carcinoma cell Tca-8113 Western blot, IFA NQO1 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Tongue squamous cell carcinoma cell SCC-4 Western blot, IFA NQO1 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Tongue squamous cell carcinoma cell SCC-15 Western blot, IFA NR2C2 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis NR2F2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NR2F6 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NR4A1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NR4A3 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis nrf2 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot Nrf2 31135953 Acute graft-versus-host-disease Mus musculus Inhibit - - Upregulation Br J Haematol - - IHC, Western blot Nrf2 25746422 Heart-toxicity Rattus norvegicus Induce Phloretin detoxicity Upregulation Eur J Pharmacol Heart myoblast H9C2 Kit Nrf2 31258454 Development-toxicity Rattus norvegicus Induce - - Downregulation Dose Response - - QRT-PCR Nrf2 22488045 Immune-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR, Western blot Nrf2 29297235 Heart-toxicity Rattus norvegicus Induce L-ascorbic-acid detoxicity Downregulation Toxicol Mech Methods Heart myoblast H9C2 RT-PCR Nrf2 29297235 Heart-toxicity Rattus norvegicus Induce Alpha-tocopherol detoxicity Downregulation Toxicol Mech Methods Heart myoblast H9C2 RT-PCR Nrf2 27608960 Heart-toxicity Rattus norvegicus Induce Imperatorin detoxicity Upregulation Toxicol In Vitro Heart myoblast H9C2 RT-PCR Nrf2 27608960 Heart-toxicity Rattus norvegicus Induce Sec-o-glucosylhamaudol detoxicity Upregulation Toxicol In Vitro Heart myoblast H9C2 RT-PCR Nrf2 22465848 Bone-toxicity Rattus norvegicus Induce - - Upregulation Bone Primary osteoblast progenitor cell Mature asteoblast Western blot Nrf2 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother Heart myoblast H9C2 Western blot NRF2 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Environ Pollut - - QRT-PCR NRF2 25966753 Reproductive-toxicity Mus musculus Induce Grape-seed-proanthocyanidin detoxicity Upregulation Biomed Environ Sci - - QRT-PCR NRF2 24327821 Heart-toxicity Rattus norvegicus Induce Resveratrol detoxicity Downregulation Evid Based Complement Alternat Med - - QRT-PCR NRF2 30257321 Bladder-cancer Homo sapiens Inhibit Bacillus calmette-guerin synergy Upregulation Biomed Pharmacother Bladder carcinoma cell 5637 QRT-PCR,Western blot NRF2 28978146 Liver-toxicity Rattus norvegicus Induce Eriodictyol detoxicity Upregulation Oncotarget - - QRT-PCR, Western blot NRF2 32154163 Leukemia Homo sapiens Inhibit L-ascorbic-acid synergy Downregulation Front Oncol Acute promyelocytic leukemia cell HL-60 RT-PCR NRF2 32154163 Leukemia Homo sapiens Inhibit Alpha-tocopherol synergy Downregulation Front Oncol Acute promyelocytic leukemia cell HL-60 RT-PCR NRF2 29697268 Liver-toxicity Homo sapiens Induce L-ascorbic-acid detoxicity Downregulation Nutr Cancer Liver cell Chang liver cell RT-PCR NRF2 29697268 Liver-toxicity Homo sapiens Induce Alpha-tocopherol detoxicity Downregulation Nutr Cancer Liver cell Chang liver cell RT-PCR NRF2 26187899 Reproductive-toxicity Mus musculus Induce Lutein detoxicity Upregulation Hum Exp Toxicol - - RT-PCR NRF2 27335833 Liver-toxicity Mus musculus Induce - - Upregulation ISRN Hepatol - - RT-PCR, Western blot NRF2 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot NRF2 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Br J Cancer Acute monocytic leukemia cell THP-1 RT-PCR, Western blot NRF2 32952848 Bladder-cancer Homo sapiens Inhibit - - Upregulation Oxid Med Cell Longev Bladder carcinoma cell T24 Western blot NRF2 32952848 Bladder-cancer Homo sapiens Inhibit - - Downregulation Oxid Med Cell Longev Bladder carcinoma cell T24 Western blot NRF2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell AsPC-1 Western blot NRF2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot NRF2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell HPAF-II Western blot NRF2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot NRF2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell PANC-1 Western blot NRF2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell YAPC Western blot NRF2 28849506 Neuronal-toxicity Mus musculus Induce Taurine detoxicity Downregulation Adv Exp Med Biol - - Western blot NRF2 19279006 Myeloma Homo sapiens Inhibit - - Upregulation J Biol Chem Multiple myeloma cell KMS-11 Western blot NRF2 27980225 Liver-toxicity Rattus norvegicus Induce Melatonin detoxicity Upregulation Oncotarget - - Western blot NRF2 27713174 Liver-toxicity Rattus norvegicus Induce Oxymatrine detoxicity Upregulation Oncotarget - - Western blot NRF2 27592447 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Osteosarcoma cell MG-63 Western blot NRF2 27561292 Liver-toxicity Rattus norvegicus Induce Allicin detoxicity Downregulation Biol Trace Elem Res - - Western blot NRF2 27291853 Liver-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Sci Rep - - Western blot NRF2 27291853 Liver-toxicity Homo sapiens Induce Taurine detoxicity Downregulation Sci Rep Hepatocellular carcinoma cell HEPG2 Western blot NRF2 27263286 Liver-cancer Homo sapiens Inhibit Aspirin synergy Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Western blot NRF2 26775255 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biochimie - - Western blot NRF2 29876539 Mammary-toxicity Homo sapiens Induce Resveratrol detoxicity Upregulation ACS Omega Breast epithelial cell MCF 10A Western blot NRF2 25341331 Liver-cancer Homo sapiens Inhibit - - Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Western blot NRF2 25003661 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Br J Cancer Acute promyelocytic leukemia cell NB4 Western blot NRF2 23285138 Myeloma Homo sapiens Inhibit - - Upregulation PLoS One Myeloma cell RPMI 8226 Western blot NRF2 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation,Downregulation Cancer Lett Oral squamous cell carcinoma cell Tca-8113 Western blot, IFA NRF2 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Tongue squamous cell carcinoma cell SCC-4 Western blot, IFA NRF2 22155346 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Tongue squamous cell carcinoma cell SCC-15 Western blot, IFA NRG3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NRIP3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NRLH2 27622732 Heart-toxicity Homo sapiens Induce - - Downregulation Chem Biol Interact Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot NS3 15273095 HCV-infection Homo sapiens Inhibit Alpha-inter-feron synergy Downregulation Antimicrob Agents Chemother Liver cancer cell Huh7 Western blot NTE 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis NTSR1 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis NUSAP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OBCAM 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis OBP2B 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ocln 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Fish Shellfish Immunol - - QRT-PCR,Western blot Ocln 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR,Western blot Ocln 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR,Western blot Ocln 32683294 Lung-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR, Western blot OCLN 32683294 Lung-toxicity Homo sapiens Induce N-acetylcysteine detoxicity Downregulation Toxicol Lett Normal lung epithelial cell BEAS-2B QRT-PCR, Western blot OCLN 32683294 Lung-toxicity Homo sapiens Induce Pd98059 detoxicity Downregulation Toxicol Lett Normal lung epithelial cell BEAS-2B QRT-PCR, Western blot OCLN 32683294 Lung-toxicity Homo sapiens Induce SB203580 detoxicity Downregulation Toxicol Lett Normal lung epithelial cell BEAS-2B QRT-PCR, Western blot OCLN 32683294 Lung-toxicity Homo sapiens Induce ML-7 detoxicity Downregulation Toxicol Lett Normal lung epithelial cell BEAS-2B Western blot OCLN 32683294 Lung-toxicity Homo sapiens Induce Resveratrol detoxicity Downregulation Toxicol Lett Normal lung epithelial cell BEAS-2B Western blot ODZ2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OGG1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OLFML2A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OLFML3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OLFR148 17275888 Endometrial-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Endometrial carcinoma cell Ishikawa Flow cytometry OLFR148 17275888 Endometrial-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Endometrial carcinoma cell ECC-1 Flow cytometry OLFR148 17275888 Endometrial-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Endometrial carcinoma cell RL-95-2 Flow cytometry OLFR148 17275888 Endometrial-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Endometrium adenocarcinoma cell HEC-1-B Flow cytometry OLIG2 30871073 Brain-cancer Homo sapiens Inhibit (-)-Gossypol synergy Downregulation Cancers (Basel) Glioma stem cell GS-5 QRT-PCR,Western blot Opa1 29867492 Heart-toxicity Mus musculus Induce Salvianolic-acid-a detoxicity Upregulation Front Pharmacol - - Western blot OPA1 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Ecotoxicol Environ Saf - - QRT-PCR OPA1 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Chemosphere - - QRT-PCR,Western blot OPA1 30516227 Kidney-toxicity Gallus gallus Induce - - Downregulation Metallomics - - QRT-PCR,Western blot OPA1 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot OPA1 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot OPA1 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR, Western blot OPCML 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OR2M1P 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ORC6 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ORL0A5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OSBPL6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OSBPL8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OSGEPL1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis OST 25543494 Anemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Bone marrow mononuclear cell BMMCs RT-PCR OTC4 27965050 Leukemia Homo sapiens Inhibit - - Downregulation J Ethnopharmacol Chronic myelogenous leukemia cell K-562 Western blot OXSR1 19996132 Liver-cancer Homo sapiens Inhibit - - Upregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling P16 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR P16 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR P16 20416177 Lymphoma Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell CA46 RT-PCR P16 17490527 Myeloma Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell U266 RT-PCR P16 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - Western blot P16 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a Western blot P16 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck squamous cell carcinoma cell UM-SCC-47 Western blot P16 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck squamous cell carcinoma cell UPCI-SCC-090 Western blot P16 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck cancer cell 93-VU-147T Western blot P16INK4 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis P16INK4 16613325 Liver-cancer Homo sapiens Inhibit - - Upregulation Hum Pathol Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot P19INK4D 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis P21 10850458 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Res Myeloma cell MC/CAR Northern blot P21 28533173 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR P21 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR P21 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR P21 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR P21 19763917 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR P21 27427852 Breast-cancer Homo sapiens Inhibit Melatonin synergy Upregulation Biomed Pharmacother Breast cancer cell MCF7 QRT-PCR P21 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR P21 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR P21 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell SW480 QRT-PCR P21 27039805 Brain-cancer Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR P21 30847385 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Mol Ther Oncolytics Pancreatic cancer cell PATU8988 QRT-PCR P21 30847385 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Mol Ther Oncolytics Pancreatic cancer cell PANC-1 QRT-PCR P21 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR P21 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR P21 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR P21 24927258 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation PLoS One Head and neck squamous cell carcinoma cell UD-SCC-2 QRT-PCR P21 24927258 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation PLoS One Head and neck squamous cell carcinoma cell UM-SCC-17B QRT-PCR P21 24927258 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation PLoS One Head and neck squamous cell carcinoma cell UM-SCC-74B QRT-PCR P21 23293885 Leukemia Homo sapiens Inhibit BIBR1532 synergy Upregulation Anticancer Agents Med Chem Acute promyelocytic leukemia cell NB4 QRT-PCR P21 21257625 Bone-toxicity Homo sapiens Induce - - Upregulation Acta Biochim Biophys Sin (Shanghai) Mesenchymal stem cells MSCs QRT-PCR, Western blot P21 18088464 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR P21 24370028 Lymphoma Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell NAMALWA RT-PCR, Western blot P21 26117010 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR P21 26883975 Prostate-cancer Homo sapiens Inhibit - - Upregulation Life Sci Prostate carcinoma cell LNCaP RT-PCR, Western blot P21 16283431 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation J Biomed Sci Epidermoid carcinoma cell A-431 RT-PCR, Western blot P21 15961274 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Cell Signal Epidermoid carcinoma cell A-431 RT-PCR, Western blot P21 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - Western blot P21 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a Western blot P21 29214213 Liver-cancer Homo sapiens Inhibit - - Upregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Western blot P21 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell MM.1S Western blot P21 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell RPMI 8226-S Western blot P21 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Hepatocellular carcinoma cell HEPG2 Western blot P21 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Liver cancer cell Huh7 Western blot P21 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Sci Epidermoid carcinoma cell A-431 Western blot P21 21278055 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Sci Keratinocyte HACAT Western blot P21 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Western blot P21 19951532 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Western blot P21 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Leuk Res Myeloma cell RPMI 8226 Western blot P21 18822310 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Epidermoid carcinoma cell A-431 Western blot P21 28013460 Skin-toxicity Mus musculus Induce - - Upregulation Environ Sci Pollut Res Int Skin fibroblast m5S Western blot P21 26883975 Prostate-cancer Homo sapiens Inhibit - - Upregulation Life Sci Prostate carcinoma cell PC-3 Western blot P21 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot P21 17390014 Cervical-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Cervix squamous cell carcinoma cell SiHa Western blot P21 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot P21 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot P21 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical carcinoma cell Ca Ski Western blot P21 30899398 Pancreas-cancer Homo sapiens Inhibit Gemcitabine synergy Upregulation Am J Transl Res Pancreatic cancer cell PATU8988 Western blot P21 30899398 Pancreas-cancer Homo sapiens Inhibit Gemcitabine synergy Upregulation Am J Transl Res Pancreatic cancer cell PANC-1 Western blot P21 15494640 Bladder-cancer Homo sapiens Inhibit - - Upregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 Western blot P21 15493360 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot P21 15493360 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot P21 15493360 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Breast cancer cell MCF7 Western blot P21 12883267 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Pancreas Pancreatic cancer cell MIA PaCa-2 Western blot P21 12679001 Leukemia Homo sapiens Inhibit 8-cpt-camp synergy Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Western blot P21 12531793 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell U266 Western blot P21 12531793 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell MC-CAR Western blot P21 12531793 Myeloma Homo sapiens Inhibit - - Upregulation Blood Burkitt's lymphoma cell HS-Sultan Western blot P21 12531793 Myeloma Homo sapiens Inhibit - - Upregulation Blood Multiple myeloma cell IM-9 Western blot P21 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot P21 12430174 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Cervical adenocarcinoma cell HeLa Western blot P21 10558879 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Head and neck cancer cell PCI-1 Western blot P21 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot P21 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot P21 25537191 Skin-cancer Homo sapiens Induce - - Downregulation Arch Toxicol Keratinocyte HACAT Western blot P21 25485499 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cell Cycle Pancreatic cancer cell MIA PaCa-2 Western blot P21 25485499 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cell Cycle Prostate carcinoma cell DU 145 Western blot P21 23548265 Lung-cancer Homo sapiens Inhibit Erlotinib synergy Upregulation Mol Cancer Ther Lung adenocarcinoma cell A549 Western blot P23 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell OPM2 Western blot P23 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot p27 31421153 Vascular-toxicity Homo sapiens Induce - - Upregulation Toxicol Lett Human umbilical vein endothelial cells HUVECs Western blot P27 26117010 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR P27 23239002 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation Chin J Integr Med Acute promyelocytic leukemia cell HL-60 Western blot P27 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell OPM2 Western blot P27 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot P27 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Western blot P27 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Leuk Res Myeloma cell RPMI 8226 Western blot P27 18937079 Liver-cancer Homo sapiens Inhibit Wortmannin synergy Upregulation Med Oncol Hepatocellular carcinoma cell HEPG2 Western blot P27 18652763 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation J Int Med Res Acute promyelocytic leukemia cell HL-60 Western blot P27 17706770 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Leuk Res Acute promyelocytic leukemia cell HL-60 Western blot P27 26629016 Leukemia Homo sapiens Inhibit Hyperoside synergy Upregulation Int J Clin Exp Med Acute promyelocytic leukemia cell HL-60 Western blot P27 16517539 Leukemia Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Western blot P27 26998898 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation Basic Clin Pharmacol Toxicol Acute promyelocytic leukemia cell NB4 Western blot, IHC P27KIP1 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis P27KIP1 28028657 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot P27KIP1 18076791 Liver-cancer Homo sapiens Inhibit - - Upregulation Ai Zheng Hepatocellular carcinoma cell SMMC-7721 Western blot P30 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot P30 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot p38 mapk 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Upregulation Environ Pollut - - Western blot P38 MAPK 18173754 Myeloma Homo sapiens Inhibit SB203580 synergy Phosphorylation Br J Haematol Myeloma cell RPMI 8226 Flow cytometry, Western blot P38 MAPK 23529539 Myeloma Homo sapiens Inhibit Cryptotanshinone synergy Phosphorylation Metallomics Myeloma cell U266 Western blot P38 MAPK 23363563 Heart-toxicity Rattus norvegicus Induce Genistein synergy Phosphorylation Cell Physiol Biochem - - Western blot P38 MAPK 23363563 Heart-toxicity Rattus norvegicus Induce Genistein synergy Phosphorylation Cell Physiol Biochem Neonatal ventricular cell NRVCs Western blot P38 MAPK 32683294 Lung-toxicity Mus musculus Induce - - Phosphorylation Toxicol Lett - - Western blot P38 MAPK 32683294 Lung-toxicity Homo sapiens Induce N-acetylcysteine detoxicity Phosphorylation Toxicol Lett Normal lung epithelial cell BEAS-2B Western blot P38 MAPK 31734849 Bone-toxicity Rattus norvegicus Induce - - Phosphorylation Arch Toxicol - - Western blot P38 MAPK 31734849 Bone-toxicity Homo sapiens Induce - - Phosphorylation Arch Toxicol Articular chondrocyte cell HC-a Western blot P38 MAPK 31319442 Lung-toxicity Rattus norvegicus Induce - - Upregulation J Appl Toxicol - - Western blot P38 MAPK 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Phosphorylation Cell Physiol Biochem Heart myoblast H9C2 Western blot P38 MAPK 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Phosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell HCCC-9810 Western blot P38 MAPK 28115242 Gastrointestinal-toxicity Homo sapiens Induce - - Phosphorylation Toxicology Colorectal adenocarcinoma cell HT-29 Western blot P38 MAPK 23253724 Skin-toxicity Homo sapiens Induce - - Dephosphorylation Chin Med J (Engl) Skin fibroblast HSFB Western blot P38 MAPK 23253724 Skin-toxicity Homo sapiens Induce - - Dephosphorylation Chin Med J (Engl) Acute monocytic leukemia cell THP-1 Western blot P38 MAPK 22488045 Immune-toxicity Mus musculus Induce - - Phosphorylation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot P38 MAPK 21946058 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Anticancer Drugs Ewing's sarcoma cell A-673 Western blot P38 MAPK 21946058 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Anticancer Drugs Ewing's sarcoma cell RD-ES Western blot P38 MAPK 21847655 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation Apoptosis Cervical adenocarcinoma cell HeLa Western blot P38 MAPK 21847655 Breast-cancer Homo sapiens Inhibit - - Phosphorylation Apoptosis Breast cancer cell MCF7 Western blot P38 MAPK 21846841 Tongue-cancer Homo sapiens Inhibit - - Upregulation J Pharmacol Exp Ther Oral squamous cell carcinoma cell Tca-8113 Western blot P38 MAPK 20862710 Breast-cancer Homo sapiens Inhibit - - Phosphorylation J Cell Biochem Breast epithelial cell MCF 10A Western blot P38 MAPK 20632473 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Environ Res Public Health Lung adenocarcinoma cell A549 Western blot P38 MAPK 20164150 Leukemia Homo sapiens Inhibit - - Upregulation Ann Oncol Leukemia cell Promyelocyte cell Western blot P38 MAPK 20129490 Blood-toxicity Homo sapiens Induce - - Phosphorylation,Downregulation Transl Res Platelet cell Platelet Western blot P38 MAPK 19720055 Leukemia Homo sapiens Inhibit Genistein synergy Upregulation,Phosphorylation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot P38 MAPK 19720055 Leukemia Homo sapiens Inhibit Dl-buthionine-(s,r)-sulfoximine synergy Upregulation,Phosphorylation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot P38 MAPK 19720055 Leukemia Homo sapiens Inhibit Adaphostin synergy Upregulation,Phosphorylation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot P38 MAPK 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation,Phosphorylation Leuk Res Myeloma cell RPMI 8226 Western blot P38 MAPK 19141569 Liver-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Ind Health Hepatocyte Hepatocytes Western blot P38 MAPK 18937079 Liver-cancer Homo sapiens Inhibit Wortmannin synergy Phosphorylation Med Oncol Hepatocellular carcinoma cell HEPG2 Western blot P38 MAPK 18728151 Lymphoma Homo sapiens Inhibit - - Phosphorylation J Leukoc Biol Lung adenocarcinoma cell A549 Western blot P38 MAPK 18636201 Lung-cancer Homo sapiens Inhibit Sulindac synergy Phosphorylation Oncol Rep Lung cancer cell NCI-H157 Western blot P38 MAPK 18546268 Leukemia Homo sapiens Inhibit Genistein synergy Phosphorylation Int J Cancer Histiocytic lymphoma cell U-937 Western blot P38 MAPK 18482988 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot P38 MAPK 18482988 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell HL-60 Western blot P38 MAPK 18482988 Breast-cancer Homo sapiens Inhibit - - Phosphorylation J Biol Chem Breast cancer cell MCF7 Western blot P38 MAPK 18412143 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation J Cell Physiol Cervical adenocarcinoma cell HeLa Western blot P38 MAPK 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot P38 MAPK 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot P38 MAPK 18299328 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Histiocytic lymphoma cell U-937 Western blot P38 MAPK 27174766 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Appl Pharmacol Brain microglia cell HAPI Western blot P38 MAPK 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Phosphorylation Mol Cell Endocrinol Breast cancer cell SK-BR-3 Western blot P38 MAPK 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot P38 MAPK 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot P38 MAPK 17331470 Leukemia Homo sapiens Inhibit - - Phosphorylation Biochem Biophys Res Commun Acute promyelocytic leukemia cell NB4 Western blot P38 MAPK 17331470 Leukemia Homo sapiens Inhibit - - Phosphorylation Biochem Biophys Res Commun Chronic myelogenous leukemia cell K-562 Western blot P38 MAPK 17237268 Leukemia Homo sapiens Inhibit Phytosphingosine synergy Phosphorylation Mol Cancer Ther Histiocytic lymphoma cell U-937 Western blot P38 MAPK 17145888 Leukemia Homo sapiens Inhibit - - Phosphorylation Cancer Res Histiocytic lymphoma cell U-937 Western blot P38 MAPK 17145888 Leukemia Homo sapiens Inhibit - - Phosphorylation Cancer Res Acute promyelocytic leukemia cell NB4 Western blot P38 MAPK 16972261 Leukemia Homo sapiens Inhibit U0126 synergy Phosphorylation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot P38 MAPK 16972261 Leukemia Homo sapiens Inhibit SP600125 synergy Phosphorylation J Cell Physiol Histiocytic lymphoma cell U-937 Western blot P38 MAPK 16818652 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Leukemia cell KT1 Western blot P38 MAPK 16445569 Breast-cancer Homo sapiens Inhibit U0126 synergy Phosphorylation Clin Exp Pharmacol Physiol Breast cancer cell MCF7 Western blot P38 MAPK 16445569 Breast-cancer Homo sapiens Inhibit Pd98059 synergy Phosphorylation Clin Exp Pharmacol Physiol Breast cancer cell MCF7 Western blot P38 MAPK 16360329 Leukemia Homo sapiens Inhibit - - Upregulation Blood Cells Mol Dis Chronic myelogenous leukemia cell K-562 Western blot P38 MAPK 16328441 Lung-cancer Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Lung adenocarcinoma cell H1355 Western blot P38 MAPK 30213730 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot P38 MAPK 29581752 Liver-cancer Homo sapiens Inhibit Megestrol-acetate synergy Upregulation,Phosphorylation Exp Ther Med Liver cancer cell BEL-7402 Western blot P38 MAPK 29540672 Immune-toxicity Mus musculus Induce - - Phosphorylation,Downregulation Cell Death Dis T lymphocyte T lymphocyte Western blot P38 MAPK 15961274 Squamous-cell-carcinoma Homo sapiens Inhibit - - Phosphorylation Cell Signal Epidermoid carcinoma cell A-431 Western blot P38 MAPK 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Testis carcinoma cell F9 Western blot P38 MAPK 15231573 Leukemia Homo sapiens Inhibit - - Phosphorylation Blood Burkitt's lymphoma cell Raji Western blot P38 MAPK 14729614 Cervical-cancer Homo sapiens Inhibit Emodin synergy Phosphorylation Cancer Res Cervical adenocarcinoma cell HeLa Western blot P38 MAPK 14610070 Leukemia Homo sapiens Inhibit 12-o-tetradecanoylphorbol-13-acetate synergy Phosphorylation J Biol Chem Histiocytic lymphoma cell U-937 Western blot P38 MAPK 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Upregulation Mol Cancer Ther Renal cell adenocarcinoma cell A-498 Western blot P38 MAPK 12883035 Kidney-cancer Homo sapiens Inhibit Gst-mda-7 synergy Upregulation Mol Cancer Ther Renal cell carcinoma cell UOK121N Western blot P38 MAPK 12480548 Kidney-cancer Homo sapiens Inhibit - - Dephosphorylation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot P38 MAPK 12296996 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biochem Mol Biol Chronic myelogenous leukemia cell K-562 Western blot P38 MAPK 12239215 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot P38 MAPK 12239215 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot P38 MAPK 12239215 Breast-cancer Homo sapiens Inhibit - - Phosphorylation J Biol Chem Breast cancer cell MCF7 Western blot P38 MAPK 12239215 Breast-cancer Homo sapiens Inhibit - - Phosphorylation J Biol Chem Prostate carcinoma cell LNCaP Western blot P38 MAPK 11454688 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Cancer Res Prostate carcinoma cell PC-3 Western blot P38 MAPK 11304686 Leukemia Homo sapiens Inhibit - - Upregulation Int J Cancer Histiocytic lymphoma cell U-937 Western blot P38 MAPK 10448126 Vascular-toxicity Sus scrofa Induce - - Phosphorylation Toxicol Appl Pharmacol Porcine aortic endothelial cell PAEC Western blot P38 MAPK 25919768 Immune-toxicity Mus musculus Induce Rapamycin synergy Phosphorylation Transplantation T cell T cell Western blot P38 MAPK 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Phosphorylation,Downregulation Cancer Lett Osteosarcoma cell HOS Western blot P38 MAPK 25449439 Bone-cancer Homo sapiens Inhibit MG132 synergy Phosphorylation,Downregulation Cancer Lett Fibrosarcoma cell HT1080 Western blot P38 MAPK 25130808 Leukemia Homo sapiens Inhibit 12-o-tetradecanoylphorbol-13-acetate synergy Phosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot P38 MAPK 24985180 Leukemia Homo sapiens Inhibit Tetradecanoylphorbol-acetate synergy Phosphorylation Zhonghua Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot P38 MAPK 24312908 Lung-cancer Homo sapiens Inhibit Indomethacin synergy Downregulation Biomed Res Int Lung adenocarcinoma cell A549 Western blot P38 MAPK 24273890 Leukemia Homo sapiens Inhibit Vitamin-K2 synergy Phosphorylation Pharmazie Acute promyelocytic leukemia cell HL-60 Western blot P38 MAPK 23926672 Prostate-cancer Homo sapiens Inhibit - - Phosphorylation Zhonghua Nan Ke Xue Prostate carcinoma cell PC-3 Western blot P38 MAPK 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Phosphorylation Toxicol Lett Heart myoblast H9C2 Western blot P38 MAPK 23664956 Heart-toxicity Rattus norvegicus Induce Metallothionein detoxicity Phosphorylation Toxicol Lett Myoblast cell H9c2 Western blot P38 MAPK 20454603 Lung-cancer Homo sapiens Inhibit - - Upregulation Met Ions Biol Med Lung adenocarcinoma cell A549 Western blot,Kit P42 16930595 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation FEBS Lett Ewing's sarcoma cell CADO-ES Western blot P42 16930595 Brain-cancer Homo sapiens Inhibit - - Dephosphorylation FEBS Lett Neuroblastoma cell SH-SY5Y Western blot P47 18424721 Immune-toxicity Homo sapiens Induce - - Phosphorylation J Immunol Primary macrophage cell Macrophage Western blot P47phox 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot P4HB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis p53 31557571 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR,Western blot p53 31307525 Leukemia Homo sapiens Inhibit Homoharringtonine synergy Upregulation J Exp Clin Cancer Res Acute myelogenous leukemia cell KG-1 Western blot p53 23121984 Liver-cancer Poeciliopsis lucida Inhibit - - Upregulation Chemosphere Hepatocellular carcinoma cell PLHC-1 Western blot P53 18167198 Liver-cancer Homo sapiens Inhibit - - Upregulation Chin Med J (Engl) Hepatocellular carcinoma cell HEPG2 ELISA P53 17064470 Liver-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Gan Zang Bing Za Zhi Hepatocellular carcinoma cell HEPG2 ELISA P53 12641444 Bone-cancer Homo sapiens Inhibit - - Upregulation Chem Res Toxicol Osteosarcoma cell U-2 OS ELISA P53 20369471 Leukemia Homo sapiens Inhibit Tanshinone-ii-a synergy Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Acute promyelocytic leukemia cell NB4 Flow cytometry P53 11589617 Lymphoma Homo sapiens Inhibit - - Downregulation Cell Biol Int Burkitt's lymphoma cell Raji Flow cytometry P53 10841286 Lymphoma Homo sapiens Inhibit - - Upregulation J Biol Regul Homeost Agents Lymphoma cell MBC-1 Flow cytometry P53 29164574 Brain-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Glioma cell U87 IFA P53 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Tumour Biol Glioblastoma cell U-87 MG IFA P53 24399651 Brain-cancer Homo sapiens Inhibit Retinoic-acid synergy Upregulation Tumour Biol Likely glioblastoma cell U-87 MG IFA P53 12490120 Lung-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Jie He He Hu Xi Za Zhi Small cell lung cancer cell NEI-H IHC P53 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis P53 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis P53 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis P53 30982490 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Res Acute myeloid leukemia cell AML-5 QRT-PCR P53 30982490 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Res Acute promyelocytic leukemia cell HL-60 QRT-PCR P53 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR P53 20530422 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Anticancer Res Colorectal adenocarcinoma cell HT-29 QRT-PCR P53 27427852 Breast-cancer Homo sapiens Inhibit Melatonin synergy Upregulation Biomed Pharmacother Breast cancer cell MCF7 QRT-PCR P53 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR P53 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR P53 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR P53 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Upregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR P53 31442540 Liver-toxicity Gallus gallus Induce - - Upregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR,Western blot P53 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Chemosphere - - QRT-PCR,Western blot P53 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot P53 30339249 Heart-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot P53 29762750 Reproductive-toxicity Gallus gallus Induce - - Upregulation Poult Sci - - QRT-PCR,Western blot P53 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot P53 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot P53 32017938 Liver-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Hepatocellular carcinoma cell HEPG2 QRT-PCR, Western blot P53 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot P53 33254717 Brain-toxicity Rattus norvegicus Induce - - Upregulation Environ Pollut - - QRT-PCR, Western blot P53 20377131 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Res Hepatocellular carcinoma cell HEPG2 RT-PCR P53 19587434 Lymphoma Homo sapiens Inhibit Adriamycin - Downregulation Zhong Nan Da Xue Xue Bao Yi Xue Ban Burkitt's lymphoma cell Raji RT-PCR P53 24738333 Lymphoma Homo sapiens Inhibit Doxorubicin synergy Upregulation J Biomed Nanotechnol Burkitt's lymphoma cell Raji RT-PCR, Western blot P53 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - Western blot P53 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a Western blot P53 31632492 Leukemia Homo sapiens Inhibit Resveratrol synergy Downregulation J Cancer Chronic myelogenous leukemia cell K-562 Western blot P53 29214213 Liver-cancer Homo sapiens Inhibit - - Upregulation Ann Clin Pathol Hepatocellular carcinoma cell HEPG2 Western blot P53 21779797 Lung-toxicity Homo sapiens Induce - - Upregulation Mol Biol Rep Pulmonary fibroblast Human pulmonary fibroblast Western blot P53 21454520 Colorectal-cancer Homo sapiens Inhibit - - Downregulation J Biol Chem Colorectal adenocarcinoma cell SW480 Western blot P53 21454520 Pancreas-cancer Homo sapiens Inhibit - - Downregulation J Biol Chem Pancreatic cancer cell MIA PaCa-2 Western blot P53 21454520 Pancreas-cancer Homo sapiens Inhibit - - Downregulation J Biol Chem Keratinocyte HACAT Western blot P53 21454520 Colorectal-cancer Homo sapiens Inhibit - - Downregulation J Biol Chem Colorectal carcinoma cell HCT116 Western blot P53 21454520 Breast-cancer Mus musculus Inhibit - - Downregulation J Biol Chem Embryonic fibroblast MEFs Western blot P53 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell OPM2 Western blot P53 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot P53 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Upregulation Autophagy Fibrosarcoma cell HT1080 Western blot P53 19608275 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Leuk Res Myeloma cell RPMI 8226 Western blot P53 19513507 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Hepatocellular carcinoma cell HEPG2 Western blot P53 19513507 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot P53 19457607 Gastric-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Gastric cancer cell MGC-803 Western blot P53 19457607 Gastric-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Gastric adenocarcinoma cell BGC823 Western blot P53 19457607 Gastric-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Gastric adenocarcinoma cell SGC-7901 Western blot P53 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Phosphorylation Free Radic Biol Med Melanoma cell C21/BASAL Western blot P53 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-1 Western blot P53 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell RPMI 8226 Western blot P53 18482988 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot P53 17507598 Kidney-cancer Mus musculus Inhibit - - Upregulation Am J Physiol Renal Physiol Kidney cell AS4.1 Western blot P53 17487067 Liver-cancer Homo sapiens Inhibit Pft-alpha detoxicity Downregulation Biomed Sci Instrum Hepatocellular carcinoma cell HEPG2 Western blot P53 17487067 Liver-toxicity Rattus norvegicus Induce Pft-alpha detoxicity Downregulation Biomed Sci Instrum Liver cell Rat liver cell Western blot P53 28013460 Skin-toxicity Mus musculus Induce - - Upregulation Environ Sci Pollut Res Int Skin fibroblast m5S Western blot P53 27638049 Development-toxicity Mus musculus Induce - - Phosphorylation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot P53 27158419 Lung-cancer Homo sapiens Inhibit - - Upregulation J Cancer Sci Ther Lung adenocarcinoma cell A549 Western blot P53 26883975 Prostate-cancer Homo sapiens Inhibit - - Upregulation Life Sci Prostate carcinoma cell LNCaP Western blot P53 26871293 Brain-cancer Homo sapiens Inhibit - - Phosphorylation Oncotarget Glioma cell U87 Western blot P53 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot P53 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot P53 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical carcinoma cell Ca Ski Western blot P53 17300860 Brain-cancer Homo sapiens Inhibit Lipoic-acid detoxicity Downregulation Food Chem Toxicol Glioblastoma cell U118 Western blot P53 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell SCC-4 Western blot P53 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell SCC-15 Western blot P53 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Life Sci Tongue squamous cell carcinoma cell CAL 27 Western blot P53 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck squamous cell carcinoma cell UM-SCC-47 Western blot P53 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck squamous cell carcinoma cell UPCI-SCC-090 Western blot P53 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck cancer cell 93-VU-147T Western blot P53 15904916 Gastric-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Gastric cancer cell MGC-803 Western blot P53 15494640 Bladder-cancer Homo sapiens Inhibit - - Upregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 Western blot P53 15352174 Breast-cancer Homo sapiens Inhibit - - Downregulation J Cell Biochem Breast cancer cell MCF7 Western blot P53 14682389 Liver-cancer Homo sapiens Inhibit - - Upregulation Cell Mol Biol (Noisy-le-grand) Hepatocellular carcinoma cell HEPG2 Western blot P53 12430174 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Cervical adenocarcinoma cell HeLa Western blot P53 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast cancer cell MCF7 Western blot P53 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast cancer cell MDA-MB-231 Western blot P53 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast epithelial carcinoma cell T-47D Western blot P53 12083632 Breast-cancer Homo sapiens Inhibit - - Upregulation Breast Cancer Res Treat Breast cancer cell BT-20 Western blot P53 11834893 Gastric-cancer Homo sapiens Inhibit - - Upregulation Pharmacology Gastric cancer cell MGC-803 Western blot P53 11146441 Gastric-cancer Homo sapiens Inhibit - - Upregulation Int J Cancer Gastric adenocarcinoma cell AGS Western blot P53 10850458 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Res Myeloma cell MC/CAR Western blot P53 26524030 Lymphoma Homo sapiens Inhibit Adriamycin synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji Western blot P53 26494474 Head-and-neck-cancer Homo sapiens Inhibit Dithiothreitol synergy Downregulation Environ Toxicol Oral cancer cell Primarily cultured cell Western blot P53 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Upregulation PLoS One Acute promyelocytic leukemia cell NB4 Western blot P53 25485499 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Cell Cycle Prostate carcinoma cell DU 145 Western blot P53 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical adenocarcinoma cell HeLa Western blot P53 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervix squamous cell carcinoma cell SiHa Western blot P53 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical carcinoma cell Ca Ski Western blot P53 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical carcinoma cell C-33A Western blot P53 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical carcinoma cell C4-I Western blot P53 25116336 Pancreas-cancer Homo sapiens Inhibit - - Downregulation PLoS One Keratinocyte HACAT Western blot P53 25116336 Pancreas-cancer Homo sapiens Inhibit - - Downregulation PLoS One Pancreatic cancer cell MIA PaCa-2 Western blot P53 24815320 Leukemia Homo sapiens Inhibit - - Phosphorylation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Western blot P53 24211095 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res B cell chronic lymphocytic leukemia cell WSU-CLL Western blot P53 23548265 Lung-cancer Homo sapiens Inhibit Erlotinib synergy Upregulation Mol Cancer Ther Lung adenocarcinoma cell A549 Western blot P53 23337567 Bone-cancer Homo sapiens Inhibit - - Phosphorylation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot P53 23337567 Bone-cancer Homo sapiens Inhibit - - Phosphorylation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot P53 23337567 Bone-cancer Rattus norvegicus Inhibit - - Phosphorylation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot P53 12063549 Brain-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Glioblastoma cell U-87 MG Western blot, IFA P53 12063549 Brain-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Glioblastoma cell T98G Western blot, IFA P53AIP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis P57 30847385 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Mol Ther Oncolytics Pancreatic cancer cell PATU8988 QRT-PCR P57 30847385 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Mol Ther Oncolytics Pancreatic cancer cell PANC-1 QRT-PCR P57 30899398 Pancreas-cancer Homo sapiens Inhibit Gemcitabine synergy Upregulation Am J Transl Res Pancreatic cancer cell PATU8988 Western blot P57 30899398 Pancreas-cancer Homo sapiens Inhibit Gemcitabine synergy Upregulation Am J Transl Res Pancreatic cancer cell PANC-1 Western blot p62 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR p62 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Downregulation PPAR Res - - QRT-PCR,Western blot p62 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot p62 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Western blot p62 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Environ Pollut - - Western blot p62 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Upregulation Int J Biochem Cell Biol - - Western blot P62 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR P62 31846860 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf Spermatogonial cell GC-1 QRT-PCR P62 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR P62 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR P62 33352257 Liver-toxicity Mus musculus Induce 3-MA detoxicity Upregulation In Vitro Normal hepatocyte AML12 QRT-PCR, Western blot P62 33352257 Liver-toxicity Mus musculus Induce Rapamycin detoxicity Upregulation In Vitro Normal hepatocyte AML12 QRT-PCR, Western blot P62 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot P62 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot P62 32112876 Reproductive-toxicity Mus musculus Induce - - Upregulation Toxicol Lett - - QRT-PCR, Western blot P62 32044640 Reproductive-toxicity Mus musculus Induce Rapamycin detoxicity Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 QRT-PCR, Western blot P62 31846860 Reproductive-toxicity Mus musculus Induce - - Downregulation Ecotoxicol Environ Saf Spermatogonial cell GC-1 Western blot P62 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - Western blot P62 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a Western blot P62 32044640 Reproductive-toxicity Mus musculus Induce 3-MA detoxicity Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 Western blot P62 29111283 Pancreas-toxicity Mus musculus Induce - - Downregulation Food Chem Toxicol - - Western blot P62 28849506 Neuronal-toxicity Mus musculus Induce Taurine detoxicity Downregulation Adv Exp Med Biol - - Western blot P62 27335833 Liver-toxicity Mus musculus Induce - - Upregulation ISRN Hepatol - - Western blot P62 22884570 Leukemia Homo sapiens Inhibit - - Downregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot P62 22884570 Lymphoma Homo sapiens Inhibit - - Downregulation FEBS Lett Leukemia cell Jurkat Western blot P62 22884570 Breast-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Breast cancer cell MCF7 Western blot P62 22884570 Gastric-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Gastric cancer cell MGC-803 Western blot P62 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell LNCaP Western blot P62 21971985 Leukemia Homo sapiens Inhibit - - Downregulation Int J Mol Med Acute promyelocytic leukemia cell HL-60 Western blot P62 21971985 Leukemia Homo sapiens Inhibit - - Downregulation Int J Mol Med Chronic myelogenous leukemia cell K-562 Western blot P62 20656687 Leukemia Homo sapiens Inhibit - - Downregulation J Biol Chem Leukemia cell KT1 Western blot P62 27291853 Liver-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Sci Rep - - Western blot P62 27291853 Liver-toxicity Homo sapiens Induce Taurine detoxicity Downregulation Sci Rep Hepatocellular carcinoma cell HEPG2 Western blot P62 30677399 Liver-toxicity Homo sapiens Induce Taurine detoxicity Downregulation Chem Biol Interact Hepatic stellate cell LX-2 Western blot P62 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Upregulation Biomed Pharmacother - - Western blot P62 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Upregulation Biomed Pharmacother Insulin-secreting cell INS-1 Western blot P62 30341298 Liver-cancer Homo sapiens Inhibit - - Upregulation Nat Commun Hepatocellular carcinoma cell HEPG2 Western blot P62 30237538 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Cell Death Dis Hepatocellular carcinoma cell HEPG2 Western blot P62 29434902 Leukemia Homo sapiens Inhibit Chloroquine synergy Downregulation Oncol Lett Acute promyelocytic leukemia cell NB4 Western blot P62 25577250 Bone-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot P62 25110043 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Rep Burkitt's lymphoma cell Raji Western blot P62 25081691 Lymphoma Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Burkitt's lymphoma cell Raji Western blot P62 24801902 Heart-toxicity Mus musculus Induce - - Upregulation Toxicology Atrial cardiomyocyte HL-1 Western blot P65 32096187 Heart-toxicity Rattus norvegicus Induce - - Upregulation,Phosphorylation Eur Rev Med Pharmacol Sci Ventricular cardiomyocyte H9c2 QRT-PCR, Western blot P65 31734849 Bone-toxicity Rattus norvegicus Induce - - Phosphorylation Arch Toxicol - - Western blot P65 31734849 Bone-toxicity Homo sapiens Induce - - Phosphorylation Arch Toxicol Articular chondrocyte cell HC-a Western blot P65 22488045 Immune-toxicity Mus musculus Induce - - Phosphorylation Arch Toxicol Lymphatic endothelial cell SVEC4-10 Western blot P65 22384180 Myeloma Homo sapiens Inhibit - - Dephosphorylation PLoS One Myeloma cell NCI-H929 Western blot P65 30612216 Breast-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Cell Biol Toxicol Breast cancer cell MDA-MB-231 Western blot P65 30612216 Breast-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Cell Biol Toxicol Breast cancer cell Hs 578T Western blot P65 30572915 Liver-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation J Exp Clin Cancer Res Liver cancer cell BEL-7402 Western blot P65 15547942 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 Western blot P65 26160715 Leukemia Homo sapiens Inhibit Pure-total-flavonoid-compounds synergy Downregulation J Zhejiang Univ Sci B Acute myeloid leukemia cell Kasumi-1 Western blot P65 24337533 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Rep Chronic myelogenous leukemia cell K-562 Western blot P65 27664319 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation Regul Toxicol Pharmacol Brain microglia cell HAPI Western blot, IFA P67 18424721 Immune-toxicity Homo sapiens Induce - - Phosphorylation J Immunol Primary macrophage cell Macrophage Western blot P67phox 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot PABPC1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR PABPC3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PAFAH1B3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Pai1 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - QRT-PCR PAI1 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a QRT-PCR PAI1 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR PAI1 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell LNCaP QRT-PCR PAICS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PAIRBP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PALM2AKAP2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PANX2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PAPD4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Park 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biomed Pharmacother - - Western blot Park 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biomed Pharmacother Insulin-secreting cell INS-1 Western blot PARN 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PARP 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 Western blot PARP 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 Western blot PARP 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Upregulation J Hematol Oncol Intrahepatic cholangiocarcinoma cell CCLP-1 Western blot PARP 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-1690 Western blot PARP 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Primary multiple myeloma cell Primary multiple myeloma cell Western blot PARP 16517539 Brain-cancer Homo sapiens Inhibit - - Upregulation Pediatr Hematol Oncol Neuroblastoma cell SK-N-AS Western blot PARP 30338810 Leukemia Homo sapiens Inhibit Chloroquine synergy Upregulation Eur Rev Med Pharmacol Sci Acute promyelocytic leukemia cell NB4 Western blot PARP 15493360 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Pancreatic cancer cell AsPC-1 Western blot PARP 15493360 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Colorectal adenocarcinoma cell HT-29 Western blot PARP 15493360 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Invest Breast cancer cell MCF7 Western blot PARP 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-1 Western blot PARP 11739184 Lymphoma Homo sapiens Inhibit - - Upregulation Blood T cell leukemia cell MT-2 Western blot PARP 11601217 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 Western blot PARP 11520058 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot PARP 11389037 Leukemia Homo sapiens Inhibit - - Upregulation Blood Histiocytic lymphoma cell U-937 Western blot PARP 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot PARP 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot PARP 10850458 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Res Myeloma cell MC/CAR Western blot PARP 10477740 Leukemia Homo sapiens Inhibit - - Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot PARP 10328107 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Burkitt's lymphoma cell NAMALWA Western blot PARP 10328107 Leukemia Homo sapiens Inhibit - - Upregulation J Natl Cancer Inst Burkitt's lymphoma cell Raji Western blot PARP 26510911 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma stem cell T387 Western blot PARP 26510911 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma stem cell T4121 Western blot PARP 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell HEPG2 Western blot PARP 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell SMMC-7721 Western blot PARP 25572414 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol lung cancer cell H841 Western blot PARP 25115845 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Acute promyelocytic leukemia cell NB4 Western blot PARP 24815320 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Western blot Parp1 32096187 Heart-toxicity Rattus norvegicus Induce - - Upregulation Eur Rev Med Pharmacol Sci Ventricular cardiomyocyte H9c2 Western blot Parp1 31525389 Liver-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Appl Pharmacol - - Western blot Parp1 31270803 Liver-toxicity Rattus norvegicus Induce - - Upregulation J Cell Physiol - - Western blot Parp1 29095437 Liver-toxicity Mus musculus Induce Metformin detoxicity Upregulation Cell Death Dis Liver cell AML12 Western blot Parp1 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Upregulation Exp Ther Med Leukemia cell WEHI-3 Western blot Parp1 28391263 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Upregulation Cell Physiol Biochem Heart myoblast H9C2 Western blot Parp1 22622864 Muscle-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Myoblast cell C2C12 Western blot Parp1 27748945 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Rep Hepatoma cell HEPA1-6 Western blot Parp1 16762916 Leukemia Mus musculus Inhibit - - Upregulation J Biol Chem Embryonic fibroblast MEFs Western blot Parp1 29767511 Reproductive-toxicity Mus musculus Induce - - Upregulation Chem Res Toxicol Embryonic stem cell CGR8 Western blot Parp1 15761769 Lymphoma Mus musculus Inhibit - - Upregulation Cancer Chemother Pharmacol B cell lymphoma cell LY-ar Western blot Parp1 15761769 Lymphoma Mus musculus Inhibit - - Upregulation Cancer Chemother Pharmacol B cell lymphoma cell LY-as Western blot PARP1 19371599 Cervical-cancer Homo sapiens Inhibit 17-DMAG synergy Upregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Flow cytometry, Western blot PARP1 19371599 Cervical-cancer Homo sapiens Inhibit Knk437 synergy Upregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Flow cytometry, Western blot PARP1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Downregulation Endocr Relat Cancer Ovarian cancer cell SK-OV-3 Western blot PARP1 33174611 Leukemia Homo sapiens Inhibit - - Upregulation Mol Med Rep Acute promyelocytic leukemia cell NB4 R1 Western blot PARP1 33174611 Leukemia Homo sapiens Inhibit - - Upregulation Mol Med Rep Acute promyelocytic leukemia cell NB4 Western blot PARP1 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Upregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H446 Western blot PARP1 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Upregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H209 Western blot PARP1 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Front Oncol Head and neck squamous cell carcinoma cell SAS HN-CICs Western blot PARP1 32290325 Lung-cancer Homo sapiens Inhibit Valproic Acid synergy Upregulation Int J Mol Sci Lung cancer cell NCI-H460 Western blot PARP1 32290325 Lung-cancer Homo sapiens Inhibit Valproic Acid synergy Upregulation Int J Mol Sci Lung cancer cell NCI-H1299 Western blot PARP1 31313788 Leukemia Homo sapiens Inhibit - - Upregulation Metallomics Acute promyelocytic leukemia cell NB4 Western blot PARP1 28927142 Lung-cancer Homo sapiens Inhibit - - Upregulation Oncol Lett Lung cancer cell SK-MES-1 Western blot PARP1 23178716 Ovary-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Ovarian carcinoma cell HEY Western blot PARP1 22922937 Myeloma Homo sapiens Inhibit Sulforaphane synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot PARP1 22922937 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot PARP1 22922937 Myeloma Homo sapiens Inhibit Erysolin synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 Western blot PARP1 22884570 Leukemia Homo sapiens Inhibit - - Downregulation FEBS Lett Chronic myelogenous leukemia cell K-562 Western blot PARP1 22884570 Lymphoma Homo sapiens Inhibit - - Downregulation FEBS Lett Leukemia cell Jurkat Western blot PARP1 22884570 Breast-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Breast cancer cell MCF7 Western blot PARP1 22884570 Gastric-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Gastric cancer cell MGC-803 Western blot PARP1 22751450 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot PARP1 22751450 Leukemia Homo sapiens Inhibit - - Upregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot PARP1 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Upregulation PLoS One Prostate carcinoma cell LNCaP Western blot PARP1 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Upregulation Int J Oncol Liver cancer cell BEL-7402 Western blot PARP1 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Hepatocellular carcinoma cell HEPG2 Western blot PARP1 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Liver cancer cell Huh7 Western blot PARP1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Chronic myelogenous leukemia cell K-562 Western blot PARP1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot PARP1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell NB4 Western blot PARP1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Acute promyelocytic leukemia cell HL-60 Western blot PARP1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Burkitt's lymphoma cell Raji Western blot PARP1 21056550 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Myeloma cell RPMI 8226 Western blot PARP1 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell OPM2 Western blot PARP1 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot PARP1 20799280 Mesothelioma Homo sapiens Inhibit - - Upregulation J Cell Physiol Mesothelioma cell NCI-H2052 Western blot PARP1 20723298 Lymphoma Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Mantle cell lymphoma cell MCL Western blot PARP1 20435036 Bladder-cancer Homo sapiens Inhibit - - Upregulation,Downregulation Exp Cell Res Bladder carcinoma cell KU7 Western blot PARP1 20200477 Fibrosarcoma Homo sapiens Inhibit Irradiation synergy Upregulation Autophagy Fibrosarcoma cell HT1080 Western blot PARP1 20171736 Leukemia Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Leuk Res B-lymphocyte b-lymphocyte Western blot PARP1 20012722 Bile-duct-cancer Homo sapiens Inhibit - - Upregulation Pathol Oncol Res Cholangiocarcinoma cell SK-CHA-1 Western blot PARP1 19468689 Leukemia Homo sapiens Inhibit - - Upregulation Invest New Drugs Acute promyelocytic leukemia cell HL-60 Western blot PARP1 19159621 Leukemia Homo sapiens Inhibit - - Upregulation Chem Biol Interact Histiocytic lymphoma cell U-937 Western blot PARP1 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-1906 Western blot PARP1 19139125 Lung-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Small cell lung cancer cell U-2020 Western blot PARP1 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-1 Western blot PARP1 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell RPMI 8226 Western blot PARP1 18539383 Lung-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Lung cancer cell CALU-6 Western blot PARP1 18538921 Leukemia Homo sapiens Inhibit ETME synergy Upregulation Cancer Lett Acute promyelocytic leukemia cell HL-60 Western blot PARP1 18439752 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Glioma cell SHG44 Western blot PARP1 17568816 Lymphoma Homo sapiens Inhibit Interferon-alpha synergy Downregulation Leukemia Lymphoma cell BC-3 Western blot PARP1 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell PC-3 Western blot PARP1 28061438 Prostate-cancer Homo sapiens Inhibit Everolimus synergy Upregulation Oncotarget Prostate carcinoma cell LNCaP Western blot PARP1 27665785 Bone-cancer Homo sapiens Inhibit Etoposide synergy Upregulation Int J Oncol Ewing's sarcoma cell A-673 Western blot PARP1 27665785 Bone-cancer Homo sapiens Inhibit Etoposide synergy Upregulation Int J Oncol Neuroblastoma cell SK-N-MC Western blot PARP1 27430728 Leukemia Homo sapiens Inhibit Curcumin synergy Upregulation Oncol Rep Myelodysplastic syndrome cell SKM-1 Western blot PARP1 27430728 Leukemia Homo sapiens Inhibit Curcumin synergy Upregulation Oncol Rep Acute myelogenous leukemia cell KG-1a Western blot PARP1 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot PARP1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell SRH Western blot PARP1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell RD Western blot PARP1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell CCA Western blot PARP1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Alveolar hrabdomyosarcomas cell RH-30 Western blot PARP1 26676886 Rhabdomyosarcoma Homo sapiens Inhibit Itraconazole synergy Upregulation Int J Oncol Rhabdomyosarcoma cell ZF Western blot PARP1 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Upregulation Mol Cell Endocrinol Breast cancer cell SK-BR-3 Western blot PARP1 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Upregulation Mol Cell Endocrinol Breast cancer cell MDA-MB-231 Western blot PARP1 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa Western blot PARP1 17145888 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Histiocytic lymphoma cell U-937 Western blot PARP1 17145888 Lymphoma Homo sapiens Inhibit - - Upregulation Cancer Res Leukemia cell Jurkat Western blot PARP1 16646077 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Ewing's sarcoma cell EW7 Western blot PARP1 16646077 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Neuroblastoma cell SK-N-MC Western blot PARP1 16467208 Leukemia Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Acute myelogenous leukemia cell AML blasts Western blot PARP1 16328441 Lung-cancer Homo sapiens Inhibit - - Downregulation Arch Toxicol Lung adenocarcinoma cell H1355 Western blot PARP1 30668372 Neuronal-toxicity Homo sapiens Induce Thymoquinone detoxicity Upregulation Phytomedicine Neuroblastoma cell SH-SY5Y Western blot PARP1 30213730 Leukemia Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 Western blot PARP1 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot PARP1 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Lett Chronic myelogenous leukemia cell K-562 Western blot PARP1 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Lett Chronic myelogenous leukemia cell KU812 Western blot PARP1 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Lett Chronic myeloid leukemia cell MEG-A2 Western blot PARP1 29774349 Leukemia Homo sapiens Inhibit - - Upregulation Metallomics Acute promyelocytic leukemia cell NB4 Western blot PARP1 16249384 Leukemia Homo sapiens Inhibit Imatinib-mesylate synergy Upregulation Blood Chronic myelogenous leukemia cell K-562 Western blot PARP1 16166054 Brain-cancer Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Neuroblastoma cell SH-SY5Y Western blot PARP1 16166054 Brain-cancer Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Neuroblastoma cell SK-N-AS Western blot PARP1 16166054 Leukemia Homo sapiens Inhibit - - Downregulation Pediatr Hematol Oncol Acute promyelocytic leukemia cell HL-60 Western blot PARP1 15604259 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Res Cervical adenocarcinoma cell HeLa Western blot PARP1 15538402 Leukemia Homo sapiens Inhibit Pd98059 synergy Upregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot PARP1 15284441 Leukemia Homo sapiens Inhibit - - Upregulation Proc Natl Acad Sci U S A Acute promyelocytic leukemia cell NB4 Western blot PARP1 15178684 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot PARP1 12760770 Head-and-neck-cancer Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation Zhonghua Kou Qiang Yi Xue Za Zhi Tongue cancer cell OSC-19 Western blot PARP1 12760770 Head-and-neck-cancer Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation Zhonghua Kou Qiang Yi Xue Za Zhi Oral squamous cell carcinoma cell Tca-8113 Western blot PARP1 12754411 Liver-cancer Homo sapiens Inhibit - - Upregulation Exp Mol Med Hepatocellular carcinoma cell HEPG2 Western blot PARP1 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell ARP-1 Western blot PARP1 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Myeloma cell U266 Western blot PARP1 12531793 Myeloma Homo sapiens Inhibit - - Upregulation Blood Burkitt's lymphoma cell HS-Sultan Western blot PARP1 12531793 Myeloma Homo sapiens Inhibit - - Downregulation Blood Multiple myeloma cell IM-9 Western blot PARP1 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot PARP1 12437633 Lymphoma Homo sapiens Inhibit - - Downregulation Br J Haematol Leukemia cell Jurkat Western blot PARP1 12430174 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Cervical adenocarcinoma cell HeLa Western blot PARP1 12174905 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Anticancer Res Pancreatic cell HPAF Western blot PARP1 12174905 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Anticancer Res Pancreatic cancer cell MIA PaCa-2 Western blot PARP1 12174905 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Anticancer Res Pancreatic cancer cell PANC-1 Western blot PARP1 12148893 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Lymphoma T cell leukemia cell MT-2 Western blot PARP1 26680881 Leukemia Homo sapiens Inhibit - - Upregulation Cancer Res Treat Acute promyelocytic leukemia cell HL-60 Western blot PARP1 12023044 Cervical-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Cervical adenocarcinoma cell HeLa Western blot PARP1 11601217 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 Western blot PARP1 11389037 Leukemia Homo sapiens Inhibit - - Upregulation Blood Acute promyelocytic leukemia cell HL-60 Western blot PARP1 10382944 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Acute promyelocytic leukemia cell NB4 Western blot PARP1 10382944 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Acute promyelocytic leukemia cell HL-60 Western blot PARP1 9864170 Leukemia Homo sapiens Inhibit Ascorbic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot PARP1 26160715 Leukemia Homo sapiens Inhibit Pure-total-flavonoid-compounds synergy Upregulation J Zhejiang Univ Sci B Acute myeloid leukemia cell Kasumi-1 Western blot PARP1 25972196 Liver-cancer Homo sapiens Inhibit - - Upregulation J Toxicol Sci Hepatocellular carcinoma cell HEPG2 Western blot PARP1 25721870 Leukemia Homo sapiens Inhibit Icariin synergy Upregulation Cell Biochem Biophys Acute promyelocytic leukemia cell HL-60 Western blot PARP1 25721870 Leukemia Homo sapiens Inhibit Icariin synergy Upregulation Cell Biochem Biophys Acute promyelocytic leukemia cell NB4 Western blot PARP1 25577250 Bone-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot PARP1 25492486 Liver-cancer Homo sapiens Inhibit Metformin synergy Upregulation Tumour Biol Hepatocellular carcinoma cell HEPG2 Western blot PARP1 25492486 Liver-cancer Homo sapiens Inhibit Metformin synergy Upregulation Tumour Biol Liver cancer cell BEL-7402 Western blot PARP1 25415199 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Myelodysplastic syndrome cell MUTZ-1 Western blot PARP1 25415199 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Myelodysplastic syndrome cell SKM-1 Western blot PARP1 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot PARP1 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot PARP1 25174355 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot PARP1 24845567 Lung-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Lung cancer cell NCI-H1299 Western blot PARP1 24482137 Gastric-cancer Homo sapiens Inhibit - - Downregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot PARP1 24482137 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot PARP1 24428916 Leukemia Homo sapiens Inhibit Buthionine-sulfoximine synergy Phosphorylation BMC Cancer Acute promyelocytic leukemia cell HL-60 Western blot PARP1 24250827 Lymphoma Homo sapiens Inhibit Interferon-alpha synergy Downregulation PLoS One Lymphoma cell BC-3 Western blot PARP1 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell 143B Western blot PARP1 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell Saos-2 Western blot PARP1 23861973 Bone-cancer Homo sapiens Inhibit - - Upregulation PLoS One Osteosarcoma cell U-2 OS Western blot PARP1 23621864 Ovary-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ovarian cancer cell HEY Western blot PARP1 23548265 Lung-cancer Homo sapiens Inhibit Erlotinib synergy Phosphorylation Mol Cancer Ther Lung adenocarcinoma cell A549 Western blot PARP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PASK1 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Upregulation Free Radic Biol Med Melanoma cell C21/GGT Western blot PASK1 19298852 Melanoma Homo sapiens Inhibit Ascorbic-acid synergy Downregulation Free Radic Biol Med Melanoma cell C21/BASAL Western blot PATCH 27784375 Myeloma Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Myeloma cell NCI-H929 QRT-PCR,Western blot Patm 28013460 Skin-toxicity Mus musculus Induce - - Upregulation Environ Sci Pollut Res Int Skin fibroblast m5S Western blot PATM 30012499 Leukemia Homo sapiens Inhibit Ruxolitinib synergy Upregulation Eur J Pharmacol Acute myelogenous leukemia cell KG-1 Western blot Patr 28013460 Skin-toxicity Mus musculus Induce - - Upregulation Environ Sci Pollut Res Int Skin fibroblast m5S Western blot PAX5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PC4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PCAF 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PCBP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PCDH19 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PCDN 12239215 Breast-cancer Homo sapiens Inhibit - - Upregulation J Biol Chem Breast cancer cell MCF7 Western blot PCF11 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PCGF2 27030546 Leukemia Homo sapiens Inhibit - - Downregulation Biochim Biophys Acta Acute promyelocytic leukemia cell NB4 Western blot Pcna 31525389 Liver-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Appl Pharmacol - - Western blot PCNA 17608231 Cataract Bos taurus Inhibit Rhizoma-curcumae synergy Downregulation Zhongguo Zhong Yao Za Zhi Lens epithelial cell LEC Flow cytometry PCNA 31637008 Liver-cancer Homo sapiens Inhibit - - Downregulation Signal Transduct Target Ther Liver cancer cell Huh7 Western blot PCNA 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioblastoma cell A-172 Western blot PCNA 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioma cell U87 Western blot PCNA 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioma cell U251 Western blot PCNA 17487067 Liver-cancer Homo sapiens Inhibit Pft-alpha detoxicity Upregulation Biomed Sci Instrum Hepatocellular carcinoma cell HEPG2 Western blot PCNA 17390014 Cervical-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Cervix squamous cell carcinoma cell SiHa Western blot PCNA 30554581 Laryngeal-cancer Homo sapiens Inhibit - - Downregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Hela carcinoma cell HEP-2 Western blot PCNA 26469751 Eye-cancer Oryctolagus cuniculus Inhibit - - Downregulation Invest Ophthalmol Vis Sci Primary TenonĄ¯s capsule fibroblast rTFs Western blot PCOLCE 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PDCD2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PDCD4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PDCD5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PDCD5 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling PDE2A 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PDGFA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PDGFBB 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung adenocarcinoma cell A549 Western blot PDGFBB 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Small cell lung cancer cell NCI-H446 Western blot PDGFRA 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR PDGFRB 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Human umbilical vein endothelial cells HUVECs Western blot PDH 12641442 Leukemia Homo sapiens Inhibit - - Downregulation Chem Res Toxicol Acute promyelocytic leukemia cell HL-60 Kit Pdk1 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Pdk1 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR PDK1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR PDK1 19242099 Brain-cancer Homo sapiens Inhibit Irradiation synergy Phosphorylation Autophagy Glioblastoma cell U-118MG Western blot PDK1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute myelogenous leukemia cell KG-1 Western blot PDK1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Leukemia cell MM6 Western blot PDK1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot PDK1 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Histiocytic lymphoma cell U-937 Western blot PDK1 24791595 Leukemia Homo sapiens Inhibit - - Phosphorylation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot PDLIM7 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM1 Western blot PDLIM7 20737493 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Head Neck Nasopharyngeal carcinoma cell NPC-BM2 Western blot PDPK1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR PDS1 19371599 Cervical-cancer Homo sapiens Inhibit 17-DMAG synergy Upregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot PDS1 19371599 Cervical-cancer Homo sapiens Inhibit Knk437 synergy Upregulation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot PDZK7 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Pepck 25859628 Pancreas-toxicity Mus musculus Induce - - Upregulation Environ Health Perspect - - QRT-PCR PER2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Pgc1 29867492 Heart-toxicity Mus musculus Induce Salvianolic-acid-a detoxicity Downregulation Front Pharmacol - - Western blot PGD 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PGD 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PGGT1B 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Pgk2 31472347 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - Western blot PGM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PGP 18072624 Leukemia Homo sapiens Inhibit Buthionine-sulfoximine synergy Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Flow cytometry PGP 17997939 Leukemia Homo sapiens Inhibit - - Downregulation Zhong Xi Yi Jie He Xue Bao Chronic myelogenous leukemia cell K-562 Flow cytometry PGP 15844663 Lung-cancer Homo sapiens Inhibit - - Downregulation J Exp Ther Oncol Lung cancer cell PG Flow cytometry PGP 12679007 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Flow cytometry PGP 19950589 Leukemia Homo sapiens Inhibit Tanshinone-ii-a synergy Downregulation Sichuan Da Xue Xue Bao Yi Xue Ban Acute promyelocytic leukemia cell MR-2 IHC PGP 15634520 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Zhong Liu Za Zhi Acute promyelocytic leukemia cell MR-2 IHC PGP 22959511 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot PGP 22959511 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot PGP 26692822 Liver-cancer Homo sapiens Inhibit 5-fluorouracil synergy Downregulation Cancer Cell Int Hepatocellular carcinoma cell HEPG2 QRT-PCR, Western blot PGP 18050736 Gastric-cancer Homo sapiens Inhibit - - Downregulation Yao Xue Xue Bao Gastric adenocarcinoma cell SGC-7901 Western blot PGP 26459009 Gastric-cancer Homo sapiens Inhibit Doxorubicin synergy Downregulation Mol Med Rep Gastric adenocarcinoma cell SGC-7901 Western blot PGP 23358330 Leukemia Homo sapiens Inhibit Realgar synergy Downregulation Biol Pharm Bull Chronic myelogenous leukemia cell K-562 Western blot PGRMC1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis PH2AX 23548265 Lung-cancer Homo sapiens Inhibit Erlotinib synergy Upregulation Mol Cancer Ther Lung adenocarcinoma cell A549 Western blot PHF1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PHI 11956606 Leukemia Homo sapiens Inhibit - - Downregulation Int J Oncol Acute promyelocytic leukemia cell HL-60 Kit PHKG2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PHLDA1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PHLDB2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis pi3k 31344536 Heart-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Environ Pollut - - Western blot Pi3k 33352257 Liver-toxicity Mus musculus Induce - - Downregulation In Vitro Normal hepatocyte AML12 QRT-PCR Pi3k 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Pi3k 31326754 Development-toxicity Mus musculus Induce - - Downregulation Chemosphere - - QRT-PCR Pi3k 27980225 Liver-toxicity Rattus norvegicus Induce Melatonin detoxicity Dephosphorylation Oncotarget - - Western blot PI3K 30646589 Breast-cancer Homo sapiens Inhibit - - Upregulation Genes (Basel) Breast cancer cell MCF7 Kit PI3K 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR PI3K 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR PI3K 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR PI3K 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR PI3K 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR PI3K 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR PI3K 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR PI3K 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR PI3K 29705899 Gastrointestinal-toxicity Gallus gallus Induce - - Downregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot PI3K 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot PI3K 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot PI3K 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot PI3K 19242099 Brain-cancer Homo sapiens Inhibit Irradiation synergy Downregulation Autophagy Glioblastoma cell U-118MG Western blot PI3K 30554581 Laryngeal-cancer Homo sapiens Inhibit - - Downregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Hela carcinoma cell HEP-2 Western blot PI3K 30014256 Ovary-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation J Biol Inorg Chem Ovarian cancer cell SK-OV-3 Western blot PI3K 30014256 Ovary-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation J Biol Inorg Chem Ovarian cancer cell A2780 Western blot PIG11 12883691 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric cancer cell MGC-803 Real-time PCR PIG11 19333544 Liver-cancer Homo sapiens Inhibit - - Upregulation J Gastroenterol Embryo hepatocyte L-O2 RT-PCR, Western blot PIG11 19333544 Liver-cancer Homo sapiens Inhibit - - Upregulation J Gastroenterol Hepatocellular carcinoma cell HEPG2 RT-PCR, Western blot PIK3CA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PIK3R2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PIM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Pin1 30093655 Breast-cancer Mus musculus Inhibit Retinoic-acid synergy Downregulation Nat Commun Embryonic fibroblast MEFs Western blot PIN1 22944098 Leukemia Homo sapiens Inhibit - - Downregulation Hematology Acute promyelocytic leukemia cell NB4 QRT-PCR PIN1 30093655 Breast-cancer Homo sapiens Inhibit Retinoic-acid synergy Downregulation Nat Commun Breast cancer cell MDA-MB-231 Western blot Pink1 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biomed Pharmacother - - Western blot PINK1 27318970 Liver-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Hepatocellular carcinoma cell HEPG2 Western blot PINX1 22944098 Leukemia Homo sapiens Inhibit - - Downregulation Hematology Acute promyelocytic leukemia cell NB4 QRT-PCR Pirh2 25116336 Pancreas-cancer Homo sapiens Inhibit - - Upregulation PLoS One Keratinocyte HACAT RT-PCR, Western blot Pirh2 25116336 Pancreas-cancer Homo sapiens Inhibit - - Upregulation PLoS One Pancreatic cancer cell MIA PaCa-2 RT-PCR, Western blot PIRH2 23271742 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation J Biol Chem Keratinocyte HACAT RT-PCR, Western blot PIRH2 23271742 Cervical-cancer Homo sapiens Inhibit - - Upregulation J Biol Chem Cervix epidermoid carcinoma cell ME-180 Western blot PKC 19322013 Bladder-cancer Homo sapiens Inhibit - - Downregulation Urol Int Bladder carcinoma cell T24 Radioimmunoassay PKC 23259068 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Treatment Acute promyelocytic leukemia cell NB4 Western blot PKC 20129490 Blood-toxicity Homo sapiens Induce - - Downregulation Transl Res Platelet cell Platelet Western blot PKC 17312995 Leukemia Homo sapiens Inhibit - - Upregulation Sci China C Life Sci Acute promyelocytic leukemia cell NB4 Western blot PKC 26540567 Leukemia Homo sapiens Inhibit - - Phosphorylation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot PKIB 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PKM2 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis PKM2 31003765 Liver-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HCCLM3 QRT-PCR,Western blot PKM2 31003765 Liver-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell SMMC-7721 QRT-PCR,Western blot PKMYT1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PKR 23259068 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Leuk Res Treatment Acute promyelocytic leukemia cell NB4 Western blot PKR 23259068 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Treatment Acute promyelocytic leukemia cell HL-60 Western blot PLA2G1B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLAC2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLAGl2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLAT 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLAU 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLAUR 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Plb 29228618 Heart-toxicity Mus musculus Induce Salvianolic-acid-b detoxicity Dephosphorylation Oncotarget - - Western blot Plb 29228618 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-b detoxicity Dephosphorylation Oncotarget Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Plb 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Downregulation Molecules Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot Plb 30717322 Heart-toxicity Rattus norvegicus Induce Salvianolic-acid-a detoxicity Downregulation Molecules - - Western blot PLCB2 16408290 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 Western blot Plcb4 24831965 Neuronal-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - QRT-PCR, Western blot PLCG1 11520058 Leukemia Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Histiocytic lymphoma cell U-937 Western blot PLCG2 20129490 Blood-toxicity Homo sapiens Induce - - Phosphorylation,Downregulation Transl Res Platelet cell Platelet Western blot PLCGl 12168106 Leukemia Homo sapiens Inhibit - - Upregulation Int J Oncol Histiocytic lymphoma cell U-937 Western blot PLCXD1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLEKHG1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLK1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute monocytic leukemia cell THP-1 QRT-PCR PLK1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Acute myeloid leukemia cell MOLM13 QRT-PCR PLK1 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 QRT-PCR PLOD1 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell MDA-MB-231 QRT-PCR PLOD1 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell SUM-159 QRT-PCR PLSCR1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PLSCR1 23621864 Ovary-cancer Homo sapiens Inhibit - - Downregulation Mol Cancer Ovarian cancer cell HEY Western blot PMAIP1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PMAIP1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PMEL 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Pml 29097844 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation J Toxicol Pathol - - Western blot Pml 28525371 Heart-toxicity Mus musculus Induce - - Upregulation Oncotarget Primary neonatal mouse cardiomyocyte Cardiomyocyte Western blot Pml 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther - - Western blot Pml 28143738 Heart-toxicity Mus musculus Induce - - Downregulation Mol Ther Neonatal cardiac fibro blast NMCFs Western blot Pml 23430110 Leukemia Mus musculus Inhibit - - Downregulation Blood Bone marrow cell Murine bone marrow cell Western blot PML 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell Flow cytometry PML 28712407 Leukemia Homo sapiens Inhibit - - Upregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi - - IFA PML 28712407 Leukemia Homo sapiens Inhibit - - Upregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Acute promyelocytic leukemia cell NB4 IFA PML 28712407 Leukemia Homo sapiens Inhibit - - Upregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Acute promyelocytic leukemia cell MR-2 IFA PML 11189513 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell MR-2 IFA PML 12452006 Leukemia Homo sapiens Inhibit - - Downregulation Ai Zheng Primary malignant cell Primary malignant cell IFA, Western blot PML 21217775 Leukemia Homo sapiens Inhibit - - Upregulation Oncogene Lymphocyte cell B cell IHC PML 16831853 Leukemia Homo sapiens Inhibit - - Downregulation Ann Oncol - - QRT-PCR PML 30203596 Leukemia Homo sapiens Inhibit - - Downregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR PML 16330433 Leukemia Homo sapiens Inhibit - - Upregulation,Downregulation Haematologica Acute promyelocytic leukemia cell NB4 QRT-PCR,Western blot PML 20416161 Leukemia Homo sapiens Inhibit Flavonoids-of-puerarin synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR PML 12667397 Liver-cancer Homo sapiens Inhibit - - Downregulation Chin Med J (Engl) Hepatocellular carcinoma cell HEPG2 Western blot PML 20378816 Leukemia Homo sapiens Inhibit - - Downregulation Science Acute promyelocytic leukemia cell NB4 Western blot PML 19549367 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Western blot PML 19468689 Leukemia Homo sapiens Inhibit - - Downregulation Invest New Drugs Acute promyelocytic leukemia cell NB4 Western blot PML 19099626 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell PR9 Western blot PML 18708055 Cervical-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Cervical adenocarcinoma cell HeLa Western blot PML 18482988 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot PML 17121903 Leukemia Homo sapiens Inhibit - - Downregulation Clin Cancer Res Embryonic kidney cell HEK-293 Western blot PML 12702573 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Res Acute promyelocytic leukemia cell NB4 Western blot PML 11480559 Leukemia Homo sapiens Inhibit Gm-csf synergy Downregulation Leukemia Acute promyelocytic leukemia cell UF-1 Western blot PML 26510911 Brain-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Glioma stem cell T387 Western blot PML 26510911 Brain-cancer Homo sapiens Inhibit - - Downregulation Oncotarget Glioma stem cell T4121 Western blot PML 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Downregulation PLoS One Acute promyelocytic leukemia cell NB4 Western blot PML 26110921 Leukemia Homo sapiens Inhibit Tetraarsenictetrasulfide synergy Downregulation PLoS One Primary acute promyelocytic leukemia cell Primary APL cell Western blot PML 25628765 Leukemia Homo sapiens Inhibit Panobinostat synergy Downregulation Clin Epigenetics Leukemia cell A/E9A;NRAS G12D Western blot PML 25241256 Lymphoma Homo sapiens Inhibit - - Downregulation Biochimie Burkitt's lymphoma cell Ramos Western blot PML 24762191 Pulmonary-fibrosis Homo sapiens Inhibit - - Downregulation Respir Res Normal human lung fibroblast NHLFs Western blot PML 23430110 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute monocytic leukemia cell THP-1 Western blot PML-RARALPHA 15625759 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell APL IFA PMS2L5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PNAS-4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PNMA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PNRC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POLD2 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis POLD3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POLDIP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POLE4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POLR2A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POLR2J2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POLR3A 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis POMT1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POPDC2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POU2F1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis POU4F1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PP2AA 18850042 Leukemia Homo sapiens Inhibit - - Downregulation Methods Find Exp Clin Pharmacol Acute promyelocytic leukemia cell NB4 Western blot PPARA 30677399 Liver-toxicity Homo sapiens Induce Taurine detoxicity Upregulation Chem Biol Interact Hepatic stellate cell LX-2 Western blot Pparg 31258454 Development-toxicity Rattus norvegicus Induce - - Downregulation Dose Response - - QRT-PCR Pparg 31205465 Rheumatoid-arthritis Mus musculus Inhibit Vitamin-D synergy Upregulation PPAR Res - - QRT-PCR,Western blot Pparg 27291853 Liver-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Sci Rep - - RT-PCR, Western blot Pparg 30551535 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biomed Pharmacother Insulin-secreting cell INS-1 Western blot PPARG 25187411 Anemia Homo sapiens Inhibit - - Downregulation Acta Biochim Biophys Sin (Shanghai) Bone marrow cell BM QRT-PCR PPARG 31205465 Rheumatoid-arthritis Homo sapiens Inhibit Vitamin-D synergy Upregulation PPAR Res Fibroblast-like synoviocyte fibroblast-like synoviocytes QRT-PCR,Western blot PPARG 22684020 Lung-cancer Homo sapiens Inhibit - - Upregulation Free Radic Biol Med Lung adenocarcinoma cell A549 QRT-PCR, Western blot PPARG 27291853 Liver-toxicity Homo sapiens Induce Taurine detoxicity Downregulation Sci Rep Hepatocellular carcinoma cell HEPG2 Western blot PPARGC1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PPGB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PPIA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PPIG 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PPIX 23962849 Brain-cancer Homo sapiens Inhibit 5-aminolevulinic-acid synergy Upregulation J Photochem Photobiol B Glioblastoma cell U-87 MG QRT-PCR,Flow cytometry PPIX 23962849 Brain-cancer Homo sapiens Inhibit 5-aminolevulinic-acid synergy Upregulation J Photochem Photobiol B Glioma cell T98MG QRT-PCR,Flow cytometry Ppkcsigma 24351555 Liver-toxicity Rattus norvegicus Induce - - Upregulation Zhonghua Yu Fang Yi Xue Za Zhi - - QRT-PCR, Western blot Ppkcsigma 24351555 Liver-toxicity Rattus norvegicus Induce - - Upregulation Zhonghua Yu Fang Yi Xue Za Zhi - - QRT-PCR, Western blot PPM1A 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PPM1D 26225652 Breast-cancer Homo sapiens Inhibit Paclitaxel synergy Downregulation Asian Pac J Cancer Prev Breast cancer cell MCF7 QRT-PCR PPP1R15A 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PPP2CA 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling PPP2CB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PPP2R5A 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ppp3ca 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR PPP4C 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis PPP6C 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRAGD 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR PRAGD 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR Pram1 19029980 Leukemia Mus musculus Inhibit Retinoic-acid synergy Downregulation Nat Med - - Luciferase Pram1 15637062 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Northern blot, Western blot Pram1 27189198 Leukemia Homo sapiens Inhibit Vorinostat synergy Downregulation J Int Med Res Acute promyelocytic leukemia cell NB4 Western blot PRAM1 9772451 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Yi Xue Za Zhi Acute promyelocytic leukemia cell NB4 IFA PRAM1 9129041 Leukemia Homo sapiens Inhibit - - Downregulation Blood Primary acute promyelocytic leukemia cell Primary APL cell IFA PRAM1 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 IFA, Western blot PRAM1 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 IFA, Western blot PRAM1 9427741 Leukemia Homo sapiens Inhibit - - Downregulation EMBO J Acute promyelocytic leukemia cell NB4 IFA, Western blot PRAM1 31313788 Leukemia Homo sapiens Inhibit - - Upregulation Metallomics Acute promyelocytic leukemia cell NB4 Western blot PRAM1 20574048 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot PRAM1 18633430 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot PRAM1 27030546 Leukemia Homo sapiens Inhibit - - Downregulation Biochim Biophys Acta Acute promyelocytic leukemia cell NB4 Western blot PRAM1 17202112 Leukemia Homo sapiens Inhibit - - Downregulation J Natl Cancer Inst Acute promyelocytic leukemia cell NB4 Western blot PRAM1 29774349 Leukemia Homo sapiens Inhibit - - Downregulation Metallomics Acute promyelocytic leukemia cell NB4 Western blot PRAM1 29362482 Leukemia Homo sapiens Inhibit Rapamycin synergy Downregulation Cell Death Dis Acute promyelocytic leukemia cell NB4 Western blot PRAM1 15781666 Leukemia Homo sapiens Inhibit 19-nor-1,25(oh)-2-d-2 synergy Downregulation Cancer Res Acute promyelocytic leukemia cell NB4 Western blot PRAM1 12750708 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot PRAM1 11480559 Leukemia Homo sapiens Inhibit Gm-csf synergy Downregulation Leukemia Acute promyelocytic leukemia cell NB4 Western blot PRAM1 11480559 Leukemia Homo sapiens Inhibit Gm-csf synergy Downregulation Leukemia Acute promyelocytic leukemia cell UF-1 Western blot PRAM1 9450572 Leukemia Homo sapiens Inhibit - - Downregulation J Natl Cancer Inst Acute promyelocytic leukemia cell NB4 Western blot PRAM1 9450572 Leukemia Homo sapiens Inhibit - - Downregulation J Natl Cancer Inst Retinoic acid-resistant leukemia cell MR6 Western blot PRAM1 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Downregulation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot PRAS40 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Acute myelogenous leukemia cell KG-1 Western blot PRAS40 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Leukemia cell MM6 Western blot PRAS40 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Chronic myelogenous leukemia cell K-562 Western blot PRAS40 18048359 Leukemia Homo sapiens Inhibit - - Phosphorylation J Biol Chem Histiocytic lymphoma cell U-937 Western blot PRB1 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervix squamous cell carcinoma cell SiHa Western blot PRC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRDX1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Prdx2 21173536 Neuronal-toxicity Mus musculus Induce - - Downregulation Ind Health - - Microarray analysis PRDX3 19408305 Leukemia Homo sapiens Inhibit - - Downregulation Int J Cancer Acute promyelocytic leukemia cell NB4 Western blot PRDX5 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PRELP 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRG4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Prkaa1 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Prkaa1 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR PRKAA1 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Phosphorylation Front Oncol Head and neck squamous cell carcinoma cell SAS HN-CICs Western blot PRKAA1 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Phosphorylation Front Oncol Head and neck squamous cell carcinoma cell SAS-CisPt R Western blot PRKAA1 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Phosphorylation Front Oncol Head and neck squamous cell carcinoma cell OECM1 HN-CICs Western blot PRKAA1 23041229 Leukemia Homo sapiens Inhibit 2-deoxy-d-glucose synergy Downregulation Biochem Pharmacol Acute promyelocytic leukemia cell HL-60 Western blot PRKAA1 18546268 Leukemia Homo sapiens Inhibit Genistein synergy Phosphorylation Int J Cancer Histiocytic lymphoma cell U-937 Western blot PRKAA1 25506699 Leukemia Homo sapiens Inhibit Etomoxir synergy Phosphorylation PLoS One Acute promyelocytic leukemia cell HL-60 Western blot PRKAA1 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Dephosphorylation Pharmazie Acute promyelocytic leukemia cell HL-60 Western blot PRKAA1 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Dephosphorylation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot PRKCB1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR PRKCBP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRKCH 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRKCZ 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR PRKD3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRPS1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRRG1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PRTN3 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR PRTN3 26892147 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Life Sci Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot PRV1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PS2 22558281 Breast-cancer Homo sapiens Inhibit - - Upregulation PLoS One Breast cancer cell MDA-MB-231 RT-PCR PS2 22558281 Breast-cancer Homo sapiens Inhibit - - Upregulation PLoS One Breast cancer cell Hs 578T RT-PCR PSA 19131511 Prostate-cancer Homo sapiens Inhibit - - Downregulation Mol Endocrinol Prostate carcinoma cell LNCaP QRT-PCR PSMA1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PSMA6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PSMB1 19549367 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 Western blot PSMB3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PSMB4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PSMB6 12852829 Leukemia Homo sapiens Inhibit - - Upregulation Acta Pharmacol Sin Acute promyelocytic leukemia cell NB4 RT-PCR PSMC5 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling PSMD1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PSMD10 19513507 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Hepatocellular carcinoma cell HEPG2 RT-PCR, Western blot PSMD10 19513507 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 RT-PCR, Western blot PSMD11 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis PSMD8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PSPH 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Ptch 31612257 Renal-fibrosis Rattus norvegicus Inhibit - - Downregulation Naunyn Schmiedebergs Arch Pharmacol - - QRT-PCR PTCH 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Rhabdoid tumor cell G-401 QRT-PCR PTCH 24420698 Rhabdoid-tumor Homo sapiens Inhibit - - Downregulation Int J Cancer Liver cancer cell Lachenmeier QRT-PCR PTCH 23867347 Leukemia Homo sapiens Inhibit - - Downregulation Acta Haematol Acute promyelocytic leukemia cell NB4 QRT-PCR PTCH 26458318 Prostate-cancer Homo sapiens Inhibit Cyclopamine synergy Downregulation Neoplasma Prostate carcinoma cell PC-3 QRT-PCR,Western blot, IFA PTCH 25577250 Bone-cancer Homo sapiens Inhibit - - Downregulation Tumour Biol Chondrosarcoma cell SW 1353 Western blot PTCH1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 PCR Array, Western blot PTCH1 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H446 QRT-PCR PTCH1 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-209(CSCs) QRT-PCR PTCH1 25082385 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Osteosarcoma cell 143B QRT-PCR PTCH1 25082385 Bone-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Hs-os-1 cell HS-OS-1 QRT-PCR PTCH1 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell 143B QRT-PCR PTCH1 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell Saos-2 QRT-PCR PTCH1 23861973 Bone-cancer Homo sapiens Inhibit - - Downregulation PLoS One Osteosarcoma cell U-2 OS QRT-PCR PTCH1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B Western blot PTCH1B 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell HSR-GBM1 QRT-PCR PTCH1B 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR PTCH1B 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40821 QRT-PCR Pten 21097842 Leukemia Cavia porcellus Inhibit - - Downregulation J Biol Chem Ventricular cardiomyocyte Ventricular cardiomyocyte Western blot PTEN 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR PTEN 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR PTEN 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR PTEN 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR PTEN 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell HL-60 QRT-PCR PTEN 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 QRT-PCR PTEN 30203596 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Primary acute promyelocytic leukemia cell Primary APL cell QRT-PCR PTEN 23497375 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Cell Int Myeloma cell RPMI 8226 QRT-PCR PTEN 23239002 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation Chin J Integr Med Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot PTEN 18652763 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation J Int Med Res Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot PTEN 28670501 Cervical-cancer Homo sapiens Inhibit - - Upregulation Exp Hematol Oncol Cervical adenocarcinoma cell HeLa Western blot PTEN 22730174 Liver-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Hepatocellular carcinoma cell HEPG2 Western blot PTEN 22730174 Liver-cancer Homo sapiens Inhibit - - Upregulation J Cell Biochem Hepatocellular carcinoma cell SMMC-7721 Western blot PTEN 20857258 Bladder-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Bladder carcinoma cell T24 Western blot PTEN 20534739 Leukemia Homo sapiens Inhibit - - Upregulation Clin Cancer Res B cell chronic lymphocytic leukemia cell B-CLL Western blot PTEN 19242099 Brain-cancer Homo sapiens Inhibit Irradiation synergy Phosphorylation Autophagy Glioblastoma cell U-118MG Western blot PTEN 18716620 Leukemia Homo sapiens Inhibit - - Upregulation Nature Acute promyelocytic leukemia cell NB4 Western blot PTEN 17332940 Myeloma Homo sapiens Inhibit - - Upregulation Int J Oncol Multiple myeloma cell IM-9 Western blot PTEN 17332940 Myeloma Homo sapiens Inhibit - - Upregulation Int J Oncol Myeloma cell U266 Western blot PTEN 26998898 Leukemia Homo sapiens Inhibit Carnosic-acid synergy Upregulation Basic Clin Pharmacol Toxicol Acute promyelocytic leukemia cell NB4 Western blot, IHC PTGER2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ptges 31713821 Immune-toxicity Cavia porcellus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR PTGES 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR PTGES 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR PTGES 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR PTGES 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR PTGES 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR PTGES 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR PTGES 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR PTGES 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR PTGES 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR PTGES 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR,Western blot PTK 11243118 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Kit PTK 17121903 Leukemia Homo sapiens Inhibit - - Downregulation Clin Cancer Res Embryonic kidney cell HEK-293 Western blot PTK9 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PTPDC1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PTPN11 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR PTPN21 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Puma 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Upregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR PUMA 28533173 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR PUMA 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell HEPG2 QRT-PCR PUMA 26410621 Liver-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Hepatocellular carcinoma cell SMMC-7721 QRT-PCR PUMA 20723298 Lymphoma Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Mantle cell lymphoma cell MCL Western blot PUMA 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-1 Western blot PUMA 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell OPM2 Western blot PUMA 18583568 Myeloma Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Myeloma cell XG-6 Western blot PUMA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell U266 Western blot PUMA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell RPMI 8226 Western blot PUMA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Myeloma cell MM.1S Western blot PUMA 18354037 Myeloma Homo sapiens Inhibit - - Upregulation Blood Multiple myeloma cell KMS-11 Western blot PUMA 17374990 Cervical-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot PUMA 16467208 Leukemia Homo sapiens Inhibit Pd184352 synergy Upregulation Blood Acute myelogenous leukemia cell AML blasts Western blot PUMA 24884809 Liver-cancer Homo sapiens Inhibit Nutlin-3 synergy Upregulation Mol Cancer Hepatocellular carcinoma cell HEPG2 Western blot PUMA 24884809 Liver-cancer Homo sapiens Inhibit Nutlin-3 synergy Upregulation Mol Cancer Hepatocellular carcinoma cell SMMC-7721 Western blot PXK 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PXMP2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PYGl 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis PZP 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis QKI 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB13 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB15 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB21 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB24 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB33A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAB33A 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR RAB5A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Rac1 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot, IFA RAC1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR RAC1 18424721 Immune-toxicity Homo sapiens Induce - - Upregulation J Immunol Primary macrophage cell Macrophage Western blot RAD17 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAD51 30871073 Brain-cancer Homo sapiens Inhibit (-)-Gossypol synergy Downregulation Cancers (Basel) Glioma stem cell GS-5 QRT-PCR RAD51L3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAD54B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAF 27794399 Lung-cancer Homo sapiens Inhibit Pd173074 synergy Dephosphorylation Lung Cancer Lung cancer cell SK-MES-1 Western blot RAF 17336041 Cervical-cancer Homo sapiens Inhibit - - Phosphorylation Cell Signal Cervical adenocarcinoma cell HeLa Western blot RAF1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAF1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis RAF1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR RAF1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR RAF1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR RAF1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR RALA 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RALGPS1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAMP2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RANBP9 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RANK 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis RAP1B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAP1GDS1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis RAP2C 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAPH1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RAPTOR 28241849 Liver-cancer Homo sapiens Inhibit Metformin synergy Dephosphorylation J Hematol Oncol Intrahepatic cholangiocarcinoma cell RBE Western blot Rara 15688020 Leukemia Cercopithecus aethiops Inhibit - - Downregulation Oncogene Kidney cell COS-1 Western blot RARa 10673743 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute promyelocytic leukemia cell NB4 RT-PCR RARa 9834237 Leukemia Homo sapiens Inhibit - - Upregulation Blood Acute promyelocytic leukemia cell NB4 Western blot RARa 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot RARa 9596679 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot RARA 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR RARB 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR RARB2 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Oncogene Testis carcinoma cell F9 RT-PCR Rarg 15688020 Leukemia Cercopithecus aethiops Inhibit - - Downregulation Oncogene Kidney cell COS-1 Western blot RARG 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Oncogene Testis carcinoma cell F9 Western blot RAS 26459009 Gastric-cancer Homo sapiens Inhibit Doxorubicin synergy Downregulation Mol Med Rep Gastric adenocarcinoma cell SGC-7901 IHC RASA1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR RASSF1A 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR RASSF1A 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MDA-MB-231 QRT-PCR RASSF1A 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR RASSF1A 16613325 Liver-cancer Homo sapiens Inhibit - - Upregulation Hum Pathol Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot RASSF1A 25330645 Nasopharyngeal-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Nasopharyngeal carcinoma cell CNE2 QRT-PCR, IHC RASSF1A 20079060 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Nasopharyngeal carcinoma cell CNE-2Z RT-PCR, Western blot RB 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Tongue squamous cell carcinoma cell SCC-4 Western blot RB 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Tongue squamous cell carcinoma cell SCC-15 Western blot RB 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Tongue squamous cell carcinoma cell CAL 27 Western blot RB 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck squamous cell carcinoma cell UM-SCC-47 Western blot RB 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck squamous cell carcinoma cell UPCI-SCC-090 Western blot RB 30243648 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Life Sci Head and neck cancer cell 93-VU-147T Western blot RB1 20953137 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Myeloma cell U266 Western blot RB1 20953137 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot RB1 19513507 Liver-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Hepatocellular carcinoma cell HEPG2 Western blot RB1 19513507 Gastric-cancer Homo sapiens Inhibit - - Upregulation Oncol Rep Gastric adenocarcinoma cell SGC-7901 Western blot RB1 12480548 Kidney-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Renal cell adenocarcinoma cell A-498 Western blot RB1 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical adenocarcinoma cell HeLa Western blot RB1 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical carcinoma cell Ca Ski Western blot RB1 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical carcinoma cell C-33A Western blot RB1 25117446 Cervical-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Cervical carcinoma cell C4-I Western blot RB1CC1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR RB1CC1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR RBBP4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RBBP6 31534777 Breast-cancer Homo sapiens Inhibit - - Downregulation Future Sci OA Breast cancer cell MCF7 RT-PCR RBL1 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast cancer cell MCF7 QRT-PCR RBL1 28218039 Breast-cancer Homo sapiens Inhibit - - Upregulation Tumour Biol Breast adenocarcinoma cell MDA-MB-468 QRT-PCR RBL1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal carcinoma cell HCT116 QRT-PCR RBL1 27769816 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Life Sci Colorectal adenocarcinoma cell HT-29 QRT-PCR RBL2 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR RBM17 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RBM23 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RBMX 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RBPMS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RCL1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis RCN3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis REG1B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RELA 25196641 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation Toxicol Lett Hepatocellular carcinoma cell MHCC97H Western blot RELA 25196641 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation Toxicol Lett Hepatocellular carcinoma cell MHCC97L Western blot RELB 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis REPIN1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis REST 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Rex1 29767511 Reproductive-toxicity Mus musculus Induce - - Downregulation Chem Res Toxicol Embryonic stem cell CGR8 QRT-PCR RGC32 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RGS11 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RGS2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RGS2 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis RHOA 18231637 Gastric-cancer Homo sapiens Inhibit Emodin synergy Upregulation Neoplasia Gastric adenocarcinoma cell SGC-7901 IHC RHOA 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR RHOA 16920938 Immune-toxicity Homo sapiens Induce - - Upregulation J Immunol Peripheral blood mononuclear cell PBMC Western blot RHOH 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RHOQ 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RHOT1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Rhox5 19679824 Mammary-toxicity Mus musculus Induce - - Upregulation Mol Pharmacol Mammary epithelial cell MM3MG RT-PCR,QRT-PCR Rhox5 19679824 Breast-cancer Mus musculus Inhibit - - Upregulation Mol Pharmacol Breast cancer cell EMT6 RT-PCR,QRT-PCR, Western blot RND1 30913205 Lung-cancer Homo sapiens Inhibit - - Downregulation Med Sci Monit Human umbilical vein endothelial cells HUVECs QRT-PCR, Western blot RNF13 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RNF138 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis RNF157 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RNF167 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RNF34 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RNU22 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RNU3IP2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RNUT1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ROCK 32954055 Vascular-toxicity Homo sapiens Induce - - Downregulation Bioact Mater Primary coronary artery smooth muscle cell PCASMCs QRT-PCR Rorc 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol CD4+T cell CD4+T cell QRT-PCR ros1 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - Biochemical assay Ros1 27748945 Liver-cancer Mus musculus Inhibit - - Upregulation Oncol Rep Hepatoma cell HEPA1-6 Flow cytometry Ros1 29095437 Liver-toxicity Mus musculus Induce Metformin detoxicity Upregulation Cell Death Dis Liver cell AML12 Flow cytometry Ros1 22622864 Muscle-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Myoblast cell C2C12 Flow cytometry Ros1 29297235 Heart-toxicity Rattus norvegicus Induce L-ascorbic-acid detoxicity Upregulation Toxicol Mech Methods Heart myoblast H9C2 Kit Ros1 29297235 Heart-toxicity Rattus norvegicus Induce Alpha-tocopherol detoxicity Upregulation Toxicol Mech Methods Heart myoblast H9C2 Kit Ros1 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Upregulation Biomed Pharmacother Heart myoblast H9C2 Kit Ros1 31059810 Muscle-toxicity Mus musculus Induce Taurine detoxicity Upregulation Int J Biochem Cell Biol Myoblast cell C2C12 Kit Ros1 18332854 Heart-toxicity Mus musculus Induce Resveratrol detoxicity Upregulation Br J Pharmacol Heart myoblast H9C2 Kit Ros1 27713174 Liver-toxicity Rattus norvegicus Induce Oxymatrine detoxicity Upregulation Oncotarget - - Kit Ros1 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Upregulation Biol Trace Elem Res Heart myoblast H9C2 Kit Ros1 25144547 Leukemia Rattus norvegicus Inhibit Resveratrol-(rev)or synergy Upregulation PLoS One Neonatal left ventricular myocyte Neonatal rat left ventricular myocytes Kit Ros1 24741408 Kidney-toxicity Rattus norvegicus Induce Resveratrol detoxicity Upregulation Nutr Res Pract - - Kit Ros1 24611105 Kidney-toxicity Rattus norvegicus Induce Astaxanthin detoxicity Upregulation Nutr Res Pract - - Kit Ros1 24327821 Heart-toxicity Rattus norvegicus Induce Resveratrol detoxicity Upregulation Evid Based Complement Alternat Med - - Kit Ros1 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell RT-PCR Ros1 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Melanoma cell B16 RT-PCR Ros1 28454374 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Hepatoma cell Heptoma 22 RT-PCR ROS1 24815320 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 ELISA ROS1 22684917 Lung-toxicity Homo sapiens Induce - - Upregulation Oncol Rep Pulmonary fibroblast HPF Flow cytometry ROS1 22293863 Lung-toxicity Homo sapiens Induce - - Upregulation Oncol Rep Pulmonary fibroblast HPF Flow cytometry ROS1 29274627 Lung-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Pharmacol Lung adenocarcinoma cell A549 Flow cytometry ROS1 20471514 Leukemia Homo sapiens Inhibit Bortezomib synergy Upregulation Cancer Genet Cytogenet Acute promyelocytic leukemia cell HL-60 Flow cytometry ROS1 18636201 Lung-cancer Homo sapiens Inhibit Sulindac synergy Upregulation Oncol Rep Lung cancer cell NCI-H157 Flow cytometry ROS1 27212442 Pancreas-cancer Homo sapiens Inhibit Px-478 synergy Upregulation Cancer Lett Pancreatic cancer cell PANC-1 Flow cytometry ROS1 27212442 Pancreas-cancer Homo sapiens Inhibit Px-478 synergy Upregulation Cancer Lett Pancreatic cancer cell BXPC-3 Flow cytometry ROS1 29708299 Lung-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Primary pulmonary artery smooth muscle cell Primary human pulmonary artery smooth muscle Flow cytometry ROS1 16045814 Cervical-cancer Homo sapiens Inhibit Emodin synergy Upregulation Cell Res Cervical adenocarcinoma cell HeLa Flow cytometry ROS1 15544921 Cervical-cancer Homo sapiens Inhibit - - Upregulation Free Radic Biol Med Esophageal carcinoma cell EC/CUHK1 Flow cytometry ROS1 11997664 Leukemia Homo sapiens Inhibit - - Upregulation Apoptosis Acute promyelocytic leukemia cell NB4 Flow cytometry ROS1 11997664 Leukemia Homo sapiens Inhibit - - Upregulation Apoptosis Histiocytic lymphoma cell U-937 Flow cytometry ROS1 11997664 Leukemia Homo sapiens Inhibit - - Upregulation Apoptosis Acute promyelocytic leukemia cell HL-60 Flow cytometry ROS1 11997664 Leukemia Homo sapiens Inhibit - - Upregulation Apoptosis Chronic myelogenous leukemia cell K-562 Flow cytometry ROS1 11956606 Leukemia Homo sapiens Inhibit - - Upregulation Int J Oncol Acute promyelocytic leukemia cell HL-60 Flow cytometry ROS1 25256833 Brain-cancer Homo sapiens Inhibit - - Upregulation Eur J Med Res Glioblastoma cell U-87 MG Flow cytometry ROS1 25256833 Brain-cancer Homo sapiens Inhibit - - Upregulation Eur J Med Res Glioblastoma cell T98G Flow cytometry ROS1 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell MUTZ-1 Flow cytometry ROS1 30898879 Myelodysplastic-syndrome Homo sapiens Inhibit Decitabine synergy Upregulation J Investig Med Myelodysplastic syndrome cell SKM-1 Flow cytometry ROS1 29467594 Breast-cancer Homo sapiens Inhibit - - Upregulation Cancer Cell Int Breast cancer cell MCF7 Flow cytometry ROS1 24107457 Neuronal-toxicity Felis catus Induce Resveratrol detoxicity Upregulation Hum Exp Toxicol - - Kit,QRT-PCR ROS1 18281123 Lung-cancer Homo sapiens Inhibit Sulindac synergy Upregulation Lung Cancer Lung cancer cell NCI-H1299 Kit ROS1 20226526 Leukemia Homo sapiens Inhibit Gefitinib synergy Upregulation Leuk Res Acute promyelocytic leukemia cell NB4 Kit ROS1 21787592 Cervical-cancer Homo sapiens Inhibit Humic-acid synergy Upregulation Environ Toxicol Pharmacol Cervical adenocarcinoma cell HeLa Kit ROS1 24428916 Leukemia Homo sapiens Inhibit Buthionine-sulfoximine synergy Upregulation BMC Cancer Acute promyelocytic leukemia cell HL-60 Kit ROS1 29314450 Neuronal-toxicity Homo sapiens Induce Ellagic-acid detoxicity Upregulation J Biochem Mol Toxicol Neuroblastoma cell SH-SY5Y Kit ROS1 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 Kit ROS1 30940653 Leukemia Homo sapiens Inhibit CB-839 synergy Upregulation Clin Cancer Res Acute myeloid leukemia cell EOL-1 Kit ROS1 30940653 Leukemia Homo sapiens Inhibit CB-839 synergy Upregulation Clin Cancer Res Acute myeloid leukemia cell MOLM13 Kit ROS1 19574005 Laryngeal-cancer Homo sapiens Inhibit L-buthionine-s,r-sulfoximine synergy Upregulation Auris Nasus Larynx Hela carcinoma cell HEP-2 Kit ROS1 27263286 Liver-cancer Homo sapiens Inhibit Aspirin synergy Upregulation Sichuan Da Xue Xue Bao Yi Xue Ban Hepatocellular carcinoma cell HEPG2 Kit ROS1 26987203 Lung-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Wei Sheng Yan Jiu Lung adenocarcinoma cell A549 Kit ROS1 30343279 Brain-cancer Homo sapiens Inhibit Resveratrol synergy Upregulation Cancer Genomics Proteomics Neuroblastoma cell SKNSH Kit ROS1 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 Kit ROS1 25147808 Liver-toxicity Felis catus Induce Resveratrol detoxicity Upregulation Biomed Res Int - - Kit ROS1 25144547 Leukemia Homo sapiens Inhibit Resveratrol-(rev)or synergy Upregulation PLoS One Acute promyelocytic leukemia cell NB4 Kit ROS1 24939418 Leukemia Homo sapiens Inhibit Bortezomib synergy Downregulation Mol Med Rep Chronic myelogenous leukemia cell K-562 Kit ROS1 24939418 Leukemia Homo sapiens Inhibit Bortezomib synergy Downregulation Mol Med Rep Chronic myelogenous leukemia cell K-562 Kit ROS1 30179145 Cervical-cancer Homo sapiens Inhibit Artemisinin synergy Upregulation Anticancer Agents Med Chem Cervical adenocarcinoma cell HeLa Kit ROS1 29697268 Liver-toxicity Homo sapiens Induce L-ascorbic-acid detoxicity Upregulation Nutr Cancer Liver cell Chang liver cell Kit ROS1 29697268 Liver-toxicity Homo sapiens Induce Alpha-tocopherol detoxicity Upregulation Nutr Cancer Liver cell Chang liver cell Kit ROS1 25115845 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Acute promyelocytic leukemia cell NB4 Kit ROS1 25115845 Leukemia Homo sapiens Inhibit - - Upregulation PLoS One Chronic myelogenous leukemia cell K-562 Kit ROXAN 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL10A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL14 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL17 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL21 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL23 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL26 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL26 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis RPL3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL36A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL37 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPL9 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPLP0 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPS25 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPS27 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis RPS27A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RPS6 17121928 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Leukemia cell KT1 Western blot RPS6 17121928 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Chronic myelogenous leukemia cell K-562 Western blot RPS6 17121928 Leukemia Homo sapiens Inhibit - - Upregulation Mol Cancer Ther Chronic myelogenous leukemia cell BV-173 Western blot RPS6KA1 23377826 Leukemia Homo sapiens Inhibit RSK1 synergy Phosphorylation Cancer Biol Ther Histiocytic lymphoma cell U-937 Western blot RPS6KA1 23377826 Leukemia Homo sapiens Inhibit RSK1 synergy Phosphorylation Cancer Biol Ther Acute myeloid leukemia cell MM6 Western blot RPS6KA1 23377826 Leukemia Homo sapiens Inhibit RSK1 synergy Phosphorylation Cancer Biol Ther Acute promyelocytic leukemia cell NB4 Western blot Rps6kb1 20299303 Skin-toxicity Mus musculus Induce - - Phosphorylation,Downregulation Environ Health Perspect Myoblast cell C2C12 Western blot RPS6KB1 17121928 Leukemia Homo sapiens Inhibit - - Phosphorylation Mol Cancer Ther Leukemia cell KT1 Kit, Western blot RPS6KB1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR RPS6KB1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Upregulation,Phosphorylation Endocr Relat Cancer Ovarian cancer cell SK-OV-3 Western blot RPS6KB1 22919067 Ovary-cancer Homo sapiens Inhibit Everolimus synergy Dephosphorylation Endocr Relat Cancer Ovarian cancer cell OV2008 Western blot RPS6KB1 23255002 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation Int J Oncol Breast cancer cell MCF7 Western blot RPS6KB1 22751450 Leukemia Homo sapiens Inhibit - - Downregulation,Dephosphorylation Leukemia Acute promyelocytic leukemia cell NB4 Western blot RPS6KB1 22363680 Prostate-cancer Homo sapiens Inhibit Irradiation synergy Dephosphorylation PLoS One Prostate carcinoma cell LNCaP Western blot RPS6KB1 20137118 Leukemia Homo sapiens Inhibit Ly294002 synergy Upregulation,Phosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot RPS6KB1 20137118 Leukemia Homo sapiens Inhibit Rapamycin synergy Upregulation,Phosphorylation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Western blot RPS6KB1 17121928 Leukemia Homo sapiens Inhibit - - Phosphorylation Mol Cancer Ther Chronic myelogenous leukemia cell K-562 Western blot RPS6KB1 25758096 Leukemia Homo sapiens Inhibit Rapamycin synergy Phosphorylation Int J Hematol Acute promyelocytic leukemia cell HL-60 Western blot RPS6KB1 25758096 Leukemia Homo sapiens Inhibit Rapamycin synergy Upregulation,Phosphorylation Int J Hematol Histiocytic lymphoma cell U-937 Western blot RPS6KB1 25577250 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Tumour Biol Chondrosarcoma cell SW 1353 Western blot RRAGD 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RRAS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RRM1 28927142 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung cancer cell SK-MES-1 Western blot RRM1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot RRM1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot RRM1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot RRM1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot RRM1 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC4006 Western blot RS3 28466809 Leukemia Homo sapiens Inhibit - - Downregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS RTN4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Runx2 22465848 Bone-toxicity Rattus norvegicus Induce - - Downregulation Bone Primary osteoblast progenitor cell Mature asteoblast QRT-PCR, RT-PCR RUNX2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis RUNX2 25187411 Anemia Homo sapiens Inhibit - - Upregulation Acta Biochim Biophys Sin (Shanghai) Bone marrow cell BM QRT-PCR RUNX3 27498627 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Rep Chronic myelogenous leukemia cell K-562 IFA RUNX3 27498627 Leukemia Homo sapiens Inhibit - - Downregulation Oncol Rep Acute promyelocytic leukemia cell NB4 IFA RUNX3 27498627 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Chronic myelogenous leukemia cell K-562 Western blot RUNX3 27498627 Leukemia Homo sapiens Inhibit - - Upregulation Oncol Rep Acute promyelocytic leukemia cell NB4 Western blot Rxra 15688020 Leukemia Cercopithecus aethiops Inhibit - - Phosphorylation Oncogene Kidney cell COS-1 Western blot RXRA 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Upregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis RXRA 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Testis carcinoma cell F9 Western blot RXRA 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Phosphorylation Oncogene Neck squamous cancer cell SQCC/Y1 Western blot RXRA 15688020 Leukemia Homo sapiens Inhibit - - Phosphorylation Oncogene Acute promyelocytic leukemia cell NB4 Western blot RY1 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis S100A11 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis S100A8 21971985 Leukemia Homo sapiens Inhibit - - Upregulation Int J Mol Med Acute promyelocytic leukemia cell HL-60 RT-PCR S100A8 21971985 Leukemia Homo sapiens Inhibit - - Upregulation Int J Mol Med Chronic myelogenous leukemia cell K-562 RT-PCR S100b 30109550 Brain-toxicity Mus musculus Induce - - Upregulation Biol Trace Elem Res - - ELISA S100B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis S391N 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR S6 24392034 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation PLoS One Breast cancer cell SK-BR-3 Western blot S6 24392034 Breast-cancer Homo sapiens Inhibit Rapamycin synergy Dephosphorylation PLoS One Breast epithelial carcinoma cell T-47D Western blot S6 22751450 Leukemia Homo sapiens Inhibit - - Dephosphorylation Leukemia Acute promyelocytic leukemia cell NB4 Western blot S6 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot S6K 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Dephosphorylation Mol Cell Endocrinol Breast cancer cell SK-BR-3 Western blot S6K 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Dephosphorylation Mol Cell Endocrinol Breast cancer cell MDA-MB-231 Western blot S6K 25416439 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Dephosphorylation Tumour Biol Liver cancer cell Huh7 Western blot S6K 23352504 Cervical-cancer Homo sapiens Inhibit Ly294002 synergy Phosphorylation Toxicol Appl Pharmacol Cervical adenocarcinoma cell HeLa-S3 Western blot SACS 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SAH 24819152 Leukemia Homo sapiens Inhibit - - Upregulation J Cell Biochem Acute promyelocytic leukemia cell NB4 HPLC SAMD8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SARM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SASH1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SAV1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SCAMP4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SCAND2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SCARF2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SCGB1D2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SCGF 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SDCBP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SDF1 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay SDF2L1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SEMA7A 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SEPP1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SERPINA6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SERPINB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SESN2 29662624 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Primary s1 GBM cell S1 GBM QRT-PCR,Western blot SET 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SEZ6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SFPQ 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SFRP1 28565807 Leukemia Homo sapiens Inhibit - - Upregulation Exp Ther Med Leukemia cell Jurkat QRT-PCR, Western blot SFRP1 26966376 Prostate-cancer Homo sapiens Inhibit - - Upregulation Onco Targets Ther Prostate carcinoma cell LNCaP QRT-PCR, Western blot SFRP1 26966376 Prostate-cancer Homo sapiens Inhibit - - Upregulation Onco Targets Ther Prostate carcinoma cell PC-3 QRT-PCR, Western blot SGK 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SH2B3 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SH3BGRl3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SH3Gl2 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis SHC1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR SHCA 23178716 Ovary-cancer Homo sapiens Inhibit - - Phosphorylation FEBS Lett Ovarian carcinoma cell HEY Western blot Shh 31612257 Renal-fibrosis Rattus norvegicus Inhibit - - Downregulation Naunyn Schmiedebergs Arch Pharmacol - - QRT-PCR SHMT1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SHP1 19619438 Lymphoma Homo sapiens Inhibit - - Methylation,Upregulation Ai Zheng Lymphoma cell T2 MS,western blot SHP1 24762999 Leukemia Homo sapiens Inhibit 5-aza-2'-deoxycytidine synergy Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 QRT-PCR SHP1 19950550 Lymphoma Homo sapiens Inhibit - - Upregulation Zhonghua Zhong Liu Za Zhi Lymphoma cell T2 QRT-PCR,Western blot SHP1 23815908 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR SHP1 29409467 Gastric-cancer Homo sapiens Inhibit - - Upregulation BMC Cancer Gastric adenocarcinoma cell AGS Western blot SHP2 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR SIAE 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SIAHBP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SIAT4B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SIGLEC1 26038719 Leukemia Homo sapiens Inhibit Vorinostat synergy Downregulation PeerJ Chronic myelogenous leukemia cell K-562 Western blot SIGLEC5 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SIGLEC7 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SIRPA 27010069 Leukemia Homo sapiens Inhibit - - Upregulation Sci Rep Acute promyelocytic leukemia cell HL-60 Western blot SIRPA 27010069 Leukemia Homo sapiens Inhibit - - Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 Western blot SIRT1 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR SIRT1 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR Sirt3 31332900 Pancreas-toxicity Rattus norvegicus Induce Metformin detoxicity Upregulation J Biochem Mol Toxicol - - ELISA Sirt3 31332900 Pancreas-toxicity Rattus norvegicus Induce Berberine detoxicity Upregulation J Biochem Mol Toxicol - - ELISA SKIL 23178716 Ovary-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Ovarian carcinoma cell HEY Western blot SKIL 20699661 Ovary-cancer Homo sapiens Inhibit - - Upregulation Autophagy Ovarian cancer cell Human ovarian cancer cell Western blot SKIL 23621864 Ovary-cancer Homo sapiens Inhibit - - Upregulation Mol Cancer Ovarian cancer cell HEY Western blot SKP2 25987041 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Pancreatic cancer cell PATU8988 QRT-PCR, Western blot SKP2 25987041 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Pancreatic cancer cell PANC-1 QRT-PCR, Western blot SKP2 30899398 Pancreas-cancer Homo sapiens Inhibit Gemcitabine synergy Downregulation Am J Transl Res Pancreatic cancer cell PATU8988 Western blot SKP2 30899398 Pancreas-cancer Homo sapiens Inhibit Gemcitabine synergy Downregulation Am J Transl Res Pancreatic cancer cell PANC-1 Western blot SKP2 30847385 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Mol Ther Oncolytics Pancreatic cancer cell PATU8988 Western blot SKP2 30847385 Pancreas-cancer Homo sapiens Inhibit - - Downregulation Mol Ther Oncolytics Pancreatic cancer cell PANC-1 Western blot SKP2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H23 Western blot SKP2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot SKP2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC827 Western blot SKP2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot SKP2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1975 Western blot SKP2 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot SKY 19925860 Blood-toxicity Homo sapiens Induce Piceatannol detoxicity Upregulation,Phosphorylation Toxicol In Vitro Neutrophil cell Neutrophil Western blot SLA2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC11A1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC24A3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC25A28 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC25A4 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SLC2A1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC2A3 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SLC41A3 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC5A6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC6A16 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC6A8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC7A1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC7A11 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SLC7A8 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLC9A1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SLUG 30983542 Pancreas-cancer Homo sapiens Inhibit Erlotinib synergy Downregulation J Chemother Pancreatic cancer cell PANC-1 QRT-PCR SM22ALPHA 32954055 Vascular-toxicity Homo sapiens Induce - - Upregulation Bioact Mater Aortic SMC cell VSMCs Western blot SM22ALPHA 32954055 Vascular-toxicity Rattus norvegicus Induce Y27632 detoxicity Downregulation Bioact Mater smooth muscle cell A7r5 Western blot SM22ALPHA 32954055 Vascular-toxicity Rattus norvegicus Induce verteporfin detoxicity Downregulation Bioact Mater smooth muscle cell A7r5 Western blot SMAD2 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SMAD2 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR, Western blot SMAD2 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell LNCaP QRT-PCR, Western blot SMAD2 24762191 Pulmonary-fibrosis Homo sapiens Inhibit - - Dephosphorylation Respir Res Normal human lung fibroblast NHLFs Western blot SMAD3 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR SMAD3 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97H QRT-PCR, Western blot SMAD3 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR, Western blot SMAD3 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell LNCaP QRT-PCR, Western blot SMAD3 21649584 Liver-cancer Homo sapiens Inhibit - - Phosphorylation Biochem J Hepatocellular carcinoma cell HEPG2 Western blot SMAD3 21649584 Liver-cancer Homo sapiens Inhibit - - Phosphorylation Biochem J Liver cancer cell Huh7 Western blot SMAD3 25196641 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H Western blot SMAD3 25196641 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97L Western blot SMAD3 24762191 Pulmonary-fibrosis Homo sapiens Inhibit - - Dephosphorylation Respir Res Normal human lung fibroblast NHLFs Western blot SMAD6 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SMAD7 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR SMAD7 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell LNCaP QRT-PCR SMARCA2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SMARCA4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SMARCB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SMC5L1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Smo 31612257 Renal-fibrosis Rattus norvegicus Inhibit - - Downregulation Naunyn Schmiedebergs Arch Pharmacol - - QRT-PCR Smo 23291299 Brain-cancer Mus musculus Inhibit - - Downregulation Cancer Cell Embryo fibroblast NIH/3T3 QRT-PCR SMO 23867347 Leukemia Homo sapiens Inhibit - - Downregulation Acta Haematol Acute promyelocytic leukemia cell NB4 QRT-PCR SMO 28823259 Leukemia Homo sapiens Inhibit Itraconazole synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myelogenous leukemia cell KG-1a Western blot SMO 26458318 Prostate-cancer Homo sapiens Inhibit Cyclopamine synergy Downregulation Neoplasma Prostate carcinoma cell PC-3 Western blot, IFA SMPD3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SNAI2 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SNAIL 30983542 Pancreas-cancer Homo sapiens Inhibit Erlotinib synergy Downregulation J Chemother Pancreatic cancer cell PANC-1 QRT-PCR SNAIL 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97L QRT-PCR SNAIL 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR,Western blot SNAIL 25304214 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Sci Hepatocellular carcinoma cell MHCC97H QRT-PCR, Western blot SNAIL 29409467 Gastric-cancer Homo sapiens Inhibit - - Downregulation BMC Cancer Gastric adenocarcinoma cell AGS Western blot SNAPC5 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SNARK 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SNCA 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SNON 20508647 Ovary-cancer Homo sapiens Inhibit - - Downregulation Cell Death Differ Ovarian carcinoma cell HEY QRT-PCR SNRPB 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis SNRPE 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SNRPF 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SNX17 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis SOCS1 19000444 Myeloma Homo sapiens Inhibit - - Upregulation Ai Zheng Myeloma cell U266 QRT-PCR SOCS1 19000444 Myeloma Homo sapiens Inhibit - - Upregulation Ai Zheng Myeloma cell RPMI 8226 QRT-PCR Sod 28092839 Heart-toxicity Mus musculus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother - - Kit Sod 28092839 Heart-toxicity Rattus norvegicus Induce Sorbus-pohuashanensis-(hante)-hedl-flavonoids detoxicity Downregulation Biomed Pharmacother Heart myoblast H9C2 Kit Sod 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR SOD 27592447 Bone-cancer Homo sapiens Inhibit - - Upregulation Int J Biochem Cell Biol Osteosarcoma cell MG-63 Kit SOD 30543957 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation Chemosphere - - Kit SOD 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - Kit SOD 31442540 Liver-toxicity Gallus gallus Induce - - - Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR,Western blot SOD 15494640 Bladder-cancer Homo sapiens Inhibit - - Upregulation Anticancer Drugs Bladder transitional carcinoma cell NTUB1 Western blot Sod1 21173536 Neuronal-toxicity Mus musculus Induce - - Downregulation Ind Health - - Microarray analysis Sod1 31473893 Liver-toxicity Mus musculus Induce - - Downregulation Biol Trace Elem Res - - QRT-PCR SOD1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SOS1 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR SOX14 28466809 Leukemia Homo sapiens Inhibit - - Upregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell HL-60 MS SOX2 24685274 Brain-cancer Homo sapiens Inhibit - - Downregulation Acta Neuropathol Commun Stem-like glioblastoma neurospheres cell 40622 QRT-PCR SOX2 30871073 Brain-cancer Homo sapiens Inhibit (-)-Gossypol synergy Downregulation Cancers (Basel) Glioma stem cell GS-5 QRT-PCR,Western blot, IFA SOX2 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot SOX2 32953511 Small cell lung cancer (SCLC) Homo sapiens Inhibit - - Downregulation Transl Lung Cancer Res Small cell lung cancer cell NCI-H209 QRT-PCR, Western blot SOX2 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Large cell lung cancer cell NCI-H460 QRT-PCR, Western blot SOX2 27158399 Lung-cancer Homo sapiens Inhibit - - Downregulation Am J Transl Res Small cell lung cancer cell NCI-H446 QRT-PCR, Western blot SOX2 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioblastoma cell A-172 RT-PCR, Western blot SOX2 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioma cell U87 Western blot SOX2 21703238 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Glioma cell U251 Western blot SOX2 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell 5-8F Western blot SOX2 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell CNE-2 Western blot SOX2 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngealcarcinoma cell 5-8F Western blot SOX2 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Nasopharyngeal carcinoma cell CNE-2 Western blot SOX9 30871073 Brain-cancer Homo sapiens Inhibit (-)-Gossypol synergy Downregulation Cancers (Basel) Glioma stem cell GS-5 QRT-PCR,Western blot SP1 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell KU7 QRT-PCR, Western blot SP1 25436934 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Lett Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot SP1 15761015 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute promyelocytic leukemia cell NB4 Western blot SP1 28768059 Heart-toxicity Homo sapiens Induce (-)-Epicatechin detoxicity Downregulation J Biochem Mol Toxicol Embryonic kidney cell HEK-293 Western blot SP1 23103450 Heart-toxicity Homo sapiens Induce Matrine detoxicity Downregulation Biochem Pharmacol Embryonic kidney cell HEK-293 Western blot SP1 23103450 Heart-toxicity Homo sapiens Induce Oxymatrine detoxicity Downregulation Biochem Pharmacol Embryonic kidney cell HEK-293 Western blot SP1 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell 253JBV Western blot SP1 18822310 Squamous-cell-carcinoma Homo sapiens Inhibit - - Upregulation Toxicol Appl Pharmacol Epidermoid carcinoma cell A-431 Western blot SP1 26892147 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Life Sci Acute promyelocytic leukemia cell HL-60 Western blot SP100 25246272 Retinoblastoma Homo sapiens Inhibit - - Downregulation Neoplasia Retinoblastoma cell Y79 Western blot SP100 25246272 Prostate-cancer Homo sapiens Inhibit - - Downregulation Neoplasia Prostate adenocarcinoma cell PC-3 Western blot SP100 25246272 Prostate-cancer Homo sapiens Inhibit - - Downregulation Neoplasia Prostate carcinoma cell DU 145 Western blot SP2 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell 253JBV Western blot SP3 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell KU7 QRT-PCR, Western blot SP4 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell KU7 QRT-PCR, Western blot SP4 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell 253JBV Western blot Spaca1 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR Spag16 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR, Western blot Spag6 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR SPATA13 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Spef2 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR SPF 25355491 Brain-cancer Homo sapiens Inhibit - - Upregulation J Mol Neurosci Glioma cell U251 Western blot SPIB 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SPINT2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SPPl2A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SPTAN1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SPTB 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SPTBN4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SPTLC2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SQSTM1 29307831 Bone-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 Western blot SQSTM1 25721868 Brain-cancer Homo sapiens Inhibit - - Downregulation Cell Physiol Biochem Glioma cell U87 Western blot SQSTM1 25721868 Brain-cancer Homo sapiens Inhibit - - Downregulation Cell Physiol Biochem Glioma cell U251 Western blot SRC 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SRC 23178716 Ovary-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Ovarian carcinoma cell HEY Western blot SRC 21777978 Lymphoma Homo sapiens Inhibit - - Phosphorylation Mol Immunol Histiocytic lymphoma cell U-937 Western blot SRC 27794399 Lung-cancer Homo sapiens Inhibit Pd173074 synergy Downregulation,Dephosphorylation Lung Cancer Lung cancer cell SK-MES-1 Western blot SRC 25537191 Skin-cancer Homo sapiens Inhibit - - Phosphorylation Arch Toxicol Keratinocyte HACAT Western blot SRD5A2 19769630 Ovary-cancer Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Sci Ovarian cancer cell COC1 Microarray analysis SREBP1C 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SREBP1C 27622732 Heart-toxicity Homo sapiens Induce - - Downregulation Chem Biol Interact Hepatocellular carcinoma cell HEPG2 QRT-PCR,Western blot Srf 22889704 Heart-toxicity Cavia porcellus Induce - - Upregulation Int J Cardiol - - Western blot SRF 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SRF 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR SSBP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SSFA2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SSX8 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ST13 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis STAR 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Stat1 23106696 Immune-toxicity Mus musculus Induce - - Downregulation Cancer Sci Leukemia cell RAW 264.7 Western blot STAT1 17121903 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res Erythroleukemia cell HEL Western blot, EMSA Stat3 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol - - IFA Stat3 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol - - IFA Stat3 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Int Immunopharmacol CD4+T cell CD4+T cell QRT-PCR Stat3 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation,Dephosphorylation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell Western blot Stat3 28454374 Skin-cancer Mus musculus Inhibit - - Dephosphorylation Oncol Lett Melanoma cell B16 Western blot Stat3 25123535 Pulmonary-fibrosis Rattus norvegicus Inhibit - - Downregulation,Dephosphorylation Life Sci - - Western blot Stat3 27174766 Neuronal-toxicity Rattus norvegicus Induce - - Phosphorylation Toxicol Appl Pharmacol Brain microglia cell HAPI Western blot, IFA STAT3 31871961 Rheumatoid-arthritis Homo sapiens Inhibit - - Downregulation Data Brief T helper cell 17 Th17 QRT-PCR STAT3 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR STAT3 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR STAT3 27039805 Brain-cancer Homo sapiens Inhibit - - Upregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR STAT3 23382965 Gastric-cancer Homo sapiens Inhibit - - Downregulation PLoS One Gastric cancer cell FU97 QRT-PCR, Western blot STAT3 23382965 Gastric-cancer Homo sapiens Inhibit - - Dephosphorylation PLoS One Gastric cancer cell FU97 QRT-PCR, Western blot STAT3 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Dephosphorylation Front Oncol Head and neck squamous cell carcinoma cell SAS-CisPt R Western blot STAT3 32351887 Head-and-neck-cancer Homo sapiens Inhibit Cisplatin synergy Dephosphorylation Front Oncol Head and neck squamous cell carcinoma cell OECM1 HN-CICs Western blot STAT3 20035426 Leukemia Homo sapiens Inhibit - - Phosphorylation,Downregulation Cancer Chemother Pharmacol Erythroleukemia cell HEL Western blot STAT3 17404111 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res Erythroleukemia cell HEL Western blot STAT3 27795556 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Leukemia Lymphoma cell DEL Western blot STAT3 27795556 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Leukemia Lymphoma cell SU-DHL-1 Western blot STAT3 27795556 Lymphoma Homo sapiens Inhibit - - Dephosphorylation Leukemia Lymphoma cell SUP-M2 Western blot STAT3 27576314 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation J Exp Clin Cancer Res Articular chondrocyte cell HCS-2/8 Western blot STAT3 26781180 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation Mol Med Rep Hepatocellular carcinoma cell MHCC97H Western blot STAT3 17121903 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res Embryonic kidney cell HEK-293 Western blot STAT3 30612216 Breast-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Cell Biol Toxicol Breast cancer cell MDA-MB-231 Western blot STAT3 30612216 Breast-cancer Homo sapiens Inhibit - - Phosphorylation,Downregulation Cell Biol Toxicol Breast cancer cell Hs 578T Western blot STAT3 30467201 Leukemia Homo sapiens Inhibit AC-73 synergy Phosphorylation,Downregulation Haematologica Histiocytic lymphoma cell U-937 Western blot STAT3 30467201 Leukemia Homo sapiens Inhibit AC-73 synergy Phosphorylation,Downregulation Haematologica Acute promyelocytic leukemia cell NB4 Western blot STAT3 30467201 Leukemia Homo sapiens Inhibit AC-73 synergy Phosphorylation,Downregulation Haematologica Biphenotypic B myelomonocytic leukemia cell MV-4-11 Western blot STAT3 29409467 Gastric-cancer Homo sapiens Inhibit - - Upregulation,Phosphorylation BMC Cancer Gastric adenocarcinoma cell AGS Western blot STAT3 12492118 Myeloma Homo sapiens Inhibit - - Dephosphorylation Mol Cancer Ther Myeloma cell U266 Western blot STAT3 12492118 Myeloma Homo sapiens Inhibit - - Dephosphorylation Mol Cancer Ther Myeloma cell MM.1S Western blot STAT3 26540567 Leukemia Homo sapiens Inhibit - - Phosphorylation Oncotarget Chronic lymphocytic leukemia cell Primary stromal cell Western blot STAT3 25196641 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation Toxicol Lett Hepatocellular carcinoma cell MHCC97H Western blot STAT3 25196641 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation Toxicol Lett Hepatocellular carcinoma cell MHCC97L Western blot STAT3 25123535 Pulmonary-fibrosis Homo sapiens Inhibit - - Phosphorylation,Downregulation Life Sci Lung adenocarcinoma cell A549 Western blot STAT3 23542114 Brain-cancer Homo sapiens Inhibit - - Upregulation,Phosphorylation Toxicol Lett Cancer stem-like cell GBM neurospheres Western blot Stat5 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol CD4+T cell CD4+T cell QRT-PCR STAT5 28276286 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leuk Lymphoma Biphenotypic B myelomonocytic leukemia cell MV-4-11 Western blot STAT5 22339968 Leukemia Homo sapiens Inhibit - - Dephosphorylation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5 Western blot STAT5 22339968 Leukemia Homo sapiens Inhibit - - Dephosphorylation Zhonghua Xue Ye Xue Za Zhi Chronic myeloid leukemia cell KBM5R Western blot STAT5 17121903 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res Erythroleukemia cell HEL Western blot STAT5 17121903 Leukemia Homo sapiens Inhibit - - Dephosphorylation Clin Cancer Res - - Western blot STAT5 30250637 Leukemia Homo sapiens Inhibit Sorafenib synergy Phosphorylation,Downregulation Oncotarget Acute myeloid leukemia cell MOLM14 Western blot STATHMIN 20657188 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa RT-PCR, Western blot STATHMIN 20657188 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervix squamous cell carcinoma cell SiHa RT-PCR, Western blot STATHMIN 28789348 Bone-cancer Homo sapiens Inhibit Doxorubicin synergy Downregulation Oncol Lett Osteosarcoma cell MG-63 Western blot STC1 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis STK24 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis STK38L 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis STRA4 15688020 Head-and-neck-cancer Homo sapiens Inhibit - - Upregulation Oncogene Testis carcinoma cell F9 RT-PCR STRBP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis STREM1 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay STRN3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis STYX 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SUGT1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Sumo1 28525371 Heart-toxicity Mus musculus Induce - - Upregulation Oncotarget Primary neonatal mouse cardiomyocyte Cardiomyocyte Western blot Sumo1 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther - - Western blot Sumo1 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther Neonatal cardiac fibro blast NMCFs Western blot SUMO1 18708055 Cervical-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Cervical adenocarcinoma cell HeLa Western blot Sumo2 28525371 Heart-toxicity Mus musculus Induce - - Upregulation Oncotarget Primary neonatal mouse cardiomyocyte Cardiomyocyte Western blot Sumo2 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther - - Western blot Sumo2 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther Neonatal cardiac fibro blast NMCFs Western blot SUMO2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SUMO2 18708055 Cervical-cancer Homo sapiens Inhibit - - Upregulation FEBS Lett Cervical adenocarcinoma cell HeLa Western blot SUPT16H 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis SURVIVIN 27770503 Leukemia Homo sapiens Inhibit - - Downregulation Asia Pac J Clin Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR SURVIVIN 23444241 Liver-cancer Oryctolagus cuniculus Inhibit - - Downregulation Croat Med J Liver cancer cell VX-2 RT-PCR Survivin 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Downregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR Survivin 28587418 Leukemia Mus musculus Inhibit Hedyotis-diffusa-willd-extract synergy Downregulation Exp Ther Med Leukemia cell WEHI-3 Western blot SURVIVIN 21473291 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Res Burkitt's lymphoma cell Raji Kit,QRT-PCR SURVIVIN 21473291 Lymphoma Homo sapiens Inhibit - - Downregulation Oncol Res Burkitt's lymphoma cell NAMALWA Kit,QRT-PCR SURVIVIN 24908354 Leukemia Homo sapiens Inhibit Deferoxamine synergy Downregulation Leuk Res Acute promyelocytic leukemia cell HL-60 IHC, IFA SURVIVIN 28533173 Leukemia Homo sapiens Inhibit - - Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR SURVIVIN 22944098 Leukemia Homo sapiens Inhibit - - Downregulation Hematology Acute promyelocytic leukemia cell NB4 QRT-PCR SURVIVIN 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR SURVIVIN 27770503 Leukemia Homo sapiens Inhibit - - Downregulation Asia Pac J Clin Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR SURVIVIN 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR SURVIVIN 30012499 Leukemia Homo sapiens Inhibit Ruxolitinib synergy Downregulation Eur J Pharmacol Histiocytic lymphoma cell U-937 QRT-PCR SURVIVIN 26170957 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Exp Ther Med Adenoid cystic carcinoma cell TNM1-2 QRT-PCR SURVIVIN 26170957 Head-and-neck-cancer Homo sapiens Inhibit - - Downregulation Exp Ther Med Adenoid cystic carcinoma cell TNM3-4 QRT-PCR SURVIVIN 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR SURVIVIN 19825857 Lung-cancer Homo sapiens Inhibit - - Downregulation Toxicol Ind Health Lung adenocarcinoma cell A549 QRT-PCR,Western blot SURVIVIN 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell KU7 QRT-PCR, Western blot SURVIVIN 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Lymphoma cell Kappas299 QRT-PCR, Western blot SURVIVIN 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 QRT-PCR, Western blot SURVIVIN 24103880 Lymphoma Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Leukemia cell Jurkat QRT-PCR, Western blot SURVIVIN 18088464 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR SURVIVIN 20416161 Leukemia Homo sapiens Inhibit Flavonoids-of-puerarin synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR SURVIVIN 19778801 Lung-cancer Homo sapiens Inhibit - - Downregulation Nan Fang Yi Ke Da Xue Xue Bao Lung cancer cell SK-MES-1 RT-PCR SURVIVIN 17869043 Laryngeal-cancer Homo sapiens Inhibit - - Downregulation Auris Nasus Larynx Hela carcinoma cell HEP-2 RT-PCR SURVIVIN 26117010 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 RT-PCR SURVIVIN 15587394 Leukemia Homo sapiens Inhibit - - Upregulation J Huazhong Univ Sci Technolog Med Sci Chronic myelogenous leukemia cell K-562 RT-PCR, Flow cytometry SURVIVIN 20635649 Rheumatoid-arthritis Homo sapiens Inhibit - - Downregulation Hua Xi Kou Qiang Yi Xue Za Zhi Adenoid cystic carcinoma cell ACC-2 RT-PCR, Western blot SURVIVIN 16950207 Lung-cancer Homo sapiens Inhibit Sulindac synergy Downregulation Biochem Pharmacol Lung adenocarcinoma cell A549 RT-PCR, Western blot SURVIVIN 24738333 Lymphoma Homo sapiens Inhibit Doxorubicin synergy Downregulation J Biomed Nanotechnol Burkitt's lymphoma cell Raji RT-PCR, Western blot SURVIVIN 23529539 Myeloma Homo sapiens Inhibit Cryptotanshinone synergy Upregulation Metallomics Myeloma cell U266 Western blot SURVIVIN 28239804 Gastric-cancer Homo sapiens Inhibit - - Downregulation Eur Rev Med Pharmacol Sci Gastric adenocarcinoma cell BGC823 Western blot SURVIVIN 28187727 Liver-cancer Homo sapiens Inhibit Cryptotanshinone synergy Upregulation BMC Complement Altern Med Liver cancer cell BEL-7404 Western blot SURVIVIN 21418039 Liver-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Int Hepatocellular carcinoma cell SMMC-7721 Western blot SURVIVIN 27794399 Lung-cancer Homo sapiens Inhibit Pd173074 synergy Upregulation Lung Cancer Lung cancer cell SK-MES-1 Western blot SURVIVIN 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Downregulation Mol Cell Endocrinol Breast cancer cell SK-BR-3 Western blot SURVIVIN 26607805 Breast-cancer Homo sapiens Inhibit Melatonin synergy Downregulation Mol Cell Endocrinol Breast cancer cell MDA-MB-231 Western blot SURVIVIN 16328441 Lung-cancer Homo sapiens Inhibit - - Downregulation Arch Toxicol Lung adenocarcinoma cell H1355 Western blot SURVIVIN 26524030 Lymphoma Homo sapiens Inhibit Adriamycin synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Burkitt's lymphoma cell Raji Western blot SURVIVIN 24211095 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Res B cell chronic lymphocytic leukemia cell WSU-CLL Western blot SURVIVIN 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell SMMC-7721 Western blot SURVIVIN 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell HEPG2 Western blot SURVIVIN 23700110 Myeloma Homo sapiens Inhibit Matrine synergy Downregulation Planta Med Myeloma cell RPMI 8226 Western blot SURVIVIN 23700110 Myeloma Homo sapiens Inhibit Matrine synergy Downregulation Planta Med Myeloma cell U266 Western blot SURVIVIN2B 27770503 Leukemia Homo sapiens Inhibit - - Downregulation Asia Pac J Clin Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR SYK 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis SYNCRIP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TA 16107885 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Leukemia Acute promyelocytic leukemia cell NB4 ELISA TACC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TAFA5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TAGAP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TAK1 28446277 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot TAK1 20159944 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Mol Pharmacol Histiocytic lymphoma cell U-937 Western blot TAK1 20159944 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Mol Pharmacol Acute promyelocytic leukemia cell NB4 Western blot TAK1 23688753 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Acute myeloid leukemia cell Kasumi-1 Western blot TAL1 25687055 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot TAL1 16360329 Leukemia Homo sapiens Inhibit - - Downregulation Blood Cells Mol Dis Chronic myelogenous leukemia cell K-562 Western blot TAL1 16360329 Leukemia Homo sapiens Inhibit - - Downregulation Blood Cells Mol Dis Erythroleukemia cell HEL Western blot TALDO1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Tank 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis TAO2 20159944 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Mol Pharmacol Histiocytic lymphoma cell U-937 Western blot TAO2 20159944 Leukemia Homo sapiens Inhibit - - Upregulation,Phosphorylation Mol Pharmacol Acute promyelocytic leukemia cell NB4 Western blot TARIL 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell OPM2 Western blot TARIL 20953137 Myeloma Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Myeloma cell RPMI 8226 Western blot TAT 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TATP73 28978663 Leukemia Homo sapiens Inhibit - - Upregulation J Leukoc Biol Acute promyelocytic leukemia cell NB4 QRT-PCR TATP73 28978663 Leukemia Homo sapiens Inhibit - - Upregulation J Leukoc Biol Acute promyelocytic leukemia cell HT93 QRT-PCR TAX 11424005 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Hematol J Lymphoma cell HuT 102 Western blot TAX 11023521 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Downregulation Blood Lymphoma cell HuT 102 Western blot TAX 11023521 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Downregulation Blood T cell leukemia cell MT-2 Western blot TBC1D15 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TBL1X 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TCEA3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TCF7L2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TCP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TCTP 21801721 Breast-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Breast cancer cell MDA-MB-231 QRT-PCR,Western blot TCTP 21801721 Breast-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Breast cancer cell MCF7 QRT-PCR,Western blot TCTP 21801721 Lung-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Lung cancer cell NCI-H727 QRT-PCR,Western blot TCTP 21801721 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Colorectal adenocarcinoma cell HT-29 QRT-PCR,Western blot TDE2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TDRD7 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TEBP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TECR 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis TEK 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis TELOMERASE ACTIVITY 17275888 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Endometrial carcinoma cell Ishikawa Kit TELOMERASE ACTIVITY 17275888 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Endometrial carcinoma cell RL-95-2 Kit TELOMERASE ACTIVITY 17275888 Endometrial-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Endometrium adenocarcinoma cell HEC-1-B Kit TERF2IP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TERT 17204170 Leukemia Homo sapiens Inhibit Cyclophosphamide synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 Southern blot, ELISA Testosterone 18630931 Reproductive-toxicity Mus musculus Induce - - Downregulation Chem Res Toxicol - - ELISA Tet1 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR Tet2 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR TET2 30213730 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Appl Pharmacol Histiocytic lymphoma cell U-937 QRT-PCR,Western blot Tet3 29223816 Neuronal-toxicity Rattus norvegicus Induce - - Downregulation Environ Pollut - - QRT-PCR TEX261 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TF 28343272 Leukemia Homo sapiens Inhibit - - Downregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR TF 11876987 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Zhonghua Xue Ye Xue Za Zhi Histiocytic lymphoma cell U-937 RT-PCR TF 17493354 Leukemia Homo sapiens Inhibit - - Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR, Flow cytometry TFDP1 17530438 Brain-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis TFE3 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot TFEB 29307831 Bone-cancer Homo sapiens Inhibit - - Dephosphorylation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR, Western blot, IHC TFEB 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Western blot Tgfb 31612257 Renal-fibrosis Rattus norvegicus Inhibit - - Downregulation Naunyn Schmiedebergs Arch Pharmacol - - QRT-PCR Tgfb1 29088724 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Oncotarget - - IHC Tgfb1 23210436 Asthma Mus musculus Inhibit - - Upregulation Can J Physiol Pharmacol - - IHC Tgfb1 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - QRT-PCR Tgfb1 27461142 Immune-toxicity Mus musculus Induce - - Downregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 QRT-PCR Tgfb1 26044521 Immune-toxicity Mus musculus Induce - - Upregulation Transpl Immunol - - QRT-PCR Tgfb1 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther - - QRT-PCR, Western blot Tgfb1 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther Neonatal cardiac fibro blast NMCFs QRT-PCR, Western blot Tgfb1 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell RT-PCR Tgfb1 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Melanoma cell B16 RT-PCR Tgfb1 28454374 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Hepatoma cell Heptoma 22 RT-PCR Tgfb1 19545743 Immune-toxicity Mus musculus Induce - - Upregulation Transplant Proc - - RT-PCR Tgfb1 23542815 Heart-toxicity Cavia porcellus Induce - - Upregulation Toxicol Lett Cardiac fibroblast Cardiac fibroblasts Western blot Tgfb1 23542815 Heart-toxicity Rattus norvegicus Induce - - Upregulation Toxicol Lett Neonatal cardiac fibroblast NRCF Western blot Tgfb1 28143738 Heart-toxicity Mus musculus Induce - - Upregulation Mol Ther - - Western blot Tgfb1 22853924 Heart-toxicity Cavia porcellus Induce - - Upregulation Cardiovasc Res - - Western blot Tgfb1 22853924 Heart-toxicity Rattus norvegicus Induce - - Upregulation Cardiovasc Res Neonatal cardiac fibroblast Cardiac fibroblasts Western blot TGFB1 28679299 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Lymphoma T cell Tregs ELISA TGFB1 29552182 Immune-toxicity Homo sapiens Induce - - Downregulation Oncol Lett Ascites-derived tumor-infiltrating lymphocyte TILs ELISA TGFB1 20723295 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell HL-60 IHC TGFB1 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a QRT-PCR TGFB1 23802174 Immune-toxicity Homo sapiens Induce - - Upregulation Immunol Invest Lymphocyte cell ALLOREACTIVE CD4+ MEMORY T CELL QRT-PCR TGFB1 29088724 Rheumatoid-arthritis Homo sapiens Inhibit - - Downregulation Oncotarget Rheumatoid arthritis fbroblast-like synoviocyte RAFLS QRT-PCR, ELISA TGFB1 25128771 Bone-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Pharmacol Osteoblasts cell HFOB1.19 Western blot TGFB1I4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TGFBR2 20508647 Ovary-cancer Homo sapiens Inhibit - - Downregulation Cell Death Differ Ovarian carcinoma cell HEY QRT-PCR TGIF 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Hepatocellular carcinoma cell HEPG2 RT-PCR, Western blot TGIF 21649584 Liver-cancer Homo sapiens Inhibit - - Upregulation Biochem J Liver cancer cell Huh7 RT-PCR, Western blot TGIF 25537191 Skin-cancer Homo sapiens Induce - - Upregulation Arch Toxicol Keratinocyte HACAT RT-PCR, Western blot TGM2 31263158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Sci Rep Acute promyelocytic leukemia cell NB4 QRT-PCR TGOLN2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Th 23518225 Neuronal-toxicity Mus musculus Induce - - Downregulation Neuroscience - - Western blot TH 11027660 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Neuroblastoma cell IMR-32 Western blot TH 11027660 Brain-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Neuroblastoma cell SH-SY5Y Western blot THROMBIN 21272920 Hematologic-toxicity Homo sapiens Induce - - Upregulation Thromb Res Human umbilical vein endothelial cells HUVECs Kit THY28 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TIGD2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TIMELESS 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TIMP1 16624393 Ovary-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Ovarian cancer cell 3AO RT-PCR, ELISA TIMP1 16624393 Ovary-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Ovary adenocarcinoma cell SW 626 RT-PCR, ELISA TIMP1 16624393 Ovary-cancer Homo sapiens Inhibit - - Upregulation Gynecol Oncol Ovarian cancer cell HO-8910PM RT-PCR, ELISA TIMP2 15962302 Fibrosarcoma Homo sapiens Inhibit - - Downregulation J Cell Biochem Fibrosarcoma cell HT1080 Northern blot,luciferase, Western blot TIMP2 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovarian cancer cell 3AO RT-PCR, ELISA TIMP2 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovary adenocarcinoma cell SW 626 RT-PCR, ELISA TIMP2 16624393 Ovary-cancer Homo sapiens Inhibit - - Downregulation Gynecol Oncol Ovarian cancer cell HO-8910PM RT-PCR, ELISA TINP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TIP60 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR TIPARP 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TIRAp 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR TISSUE FACTOR 26051726 Leukemia Homo sapiens Inhibit Daunorubicin synergy Downregulation Pak J Pharm Sci Acute promyelocytic leukemia cell NB4 ELISA TISSUE FACTOR 11798779 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Zhonghua Yi Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR TISSUE FACTOR 11798779 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Zhonghua Yi Xue Za Zhi Acute promyelocytic leukemia cell APL RT-PCR TISSUE FACTOR 11798557 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Nei Ke Za Zhi Acute promyelocytic leukemia cell APL RT-PCR TISSUE FACTOR 11779431 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Chin Med J (Engl) Acute promyelocytic leukemia cell NB4 RT-PCR TISSUE FACTOR 11721405 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR TISSUE FACTOR 10803529 Leukemia Homo sapiens Inhibit - - Downregulation Leukemia Acute promyelocytic leukemia cell NB4 RT-PCR, ELISA TISSUE FACTOR 11189487 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Bone marrow cell Bone marrow blasts RT-PCR, ELISA Tjp1 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR Tjp1 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR Tjp1 32683294 Lung-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - Western blot Tjp2 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR Tjp2 30225639 Neuronal-toxicity Mus musculus Induce - - Downregulation Arch Toxicol - - QRT-PCR Tjp2 32683294 Lung-toxicity Mus musculus Induce - - Downregulation Toxicol Lett - - Western blot Tk 18822301 Lymphoma Mus musculus Inhibit - - Downregulation Mutat Res Lymphoma cell L5178Y RT-PCR TK 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Non-small cell lung cancer cell H358 Western blot TK 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell H1650 Western blot TK 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC2935 Western blot TK 25174355 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell HCC4006 Western blot TLE2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TLN2 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis TLR3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TLR4 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR TM4SF1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TM4SF4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TMEM10 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Tmf1 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR TMLHE 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TMPO 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TMS1 24993472 Leukemia Homo sapiens Inhibit - - Upregulation Acta Haematol Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot TMS1 24666483 Leukemia Homo sapiens Inhibit - - Upregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 RT-PCR, Western blot Tnf 31177080 Rheumatoid-arthritis Mus musculus Inhibit - - Upregulation Int Immunopharmacol CD4+T cell CD4+T cell ELISA Tnf 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell ELISA Tnf 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Melanoma cell B16 ELISA Tnf 12154019 Fibrosarcoma Mus musculus Inhibit - - Upregulation Cancer Res Fibrosarcoma cell Meth-A ELISA Tnf 12154019 Fibrosarcoma Mus musculus Inhibit - - Upregulation Cancer Res Fibrosarcoma cell Meth-A ELISA Tnf 12154019 Fibrosarcoma Mus musculus Inhibit - - Upregulation Cancer Res Fibrosarcoma cell Meth-A ELISA Tnf 31734849 Bone-toxicity Rattus norvegicus Induce - - Upregulation Arch Toxicol - - QRT-PCR Tnf 27461142 Immune-toxicity Mus musculus Induce - - Downregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 QRT-PCR Tnf 29049341 Immune-toxicity Mus musculus Induce - - Upregulation PLoS One Splenocyte Splenocytes QRT-PCR, ELISA Tnf 25413961 Lung-cancer Mus musculus Inhibit - - Downregulation Cell Biochem Biophys Lung cancer cell LEWIS QRT-PCR, Western blot Tnf 19545743 Immune-toxicity Mus musculus Induce - - Downregulation Transplant Proc - - RT-PCR Tnf 17517186 Lymphoma Rattus norvegicus Inhibit - - Upregulation Chin Med J (Engl) Pancreatic acinar cell Pancreatic acinar cell RT-PCR Tnf 12243866 Leukemia Mus musculus Inhibit - - Downregulation Toxicol Lett Myeloid leukemia cell JCS-16 RT-PCR TNF 20501519 Immune-toxicity Homo sapiens Induce - - Upregulation Hum Exp Toxicol Neutrophil cell Neutrophil Antibody array assay TNF 28404891 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Oncotarget Acute promyelocytic leukemia cell NB4 ELISA TNF 28404891 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Upregulation Oncotarget Acute promyelocytic leukemia cell HL-60 ELISA TNF 23253724 Skin-toxicity Homo sapiens Induce - - Downregulation Chin Med J (Engl) Acute monocytic leukemia cell THP-1 ELISA TNF 16920938 Immune-toxicity Homo sapiens Induce - - Upregulation J Immunol Peripheral blood mononuclear cell PBMC ELISA TNF 31078158 Leukemia Homo sapiens Inhibit Retinoic-acid synergy Downregulation Cell Mol Biol (Noisy-le-grand) Acute promyelocytic leukemia cell NB4 Kit TNF 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis TNF 31734849 Bone-toxicity Homo sapiens Induce - - Upregulation Arch Toxicol Articular chondrocyte cell HC-a QRT-PCR TNF 29228677 Kidney-toxicity Gallus gallus Induce - - Upregulation Oncotarget - - QRT-PCR TNF 28343272 Leukemia Homo sapiens Inhibit - - Downregulation Ann Hematol Acute promyelocytic leukemia cell NB4 QRT-PCR TNF 30145471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Int Immunopharmacol - - QRT-PCR TNF 31473897 Gastrointestinal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Biol Trace Elem Res - - QRT-PCR,Western blot TNF 30516227 Kidney-toxicity Gallus gallus Induce - - Upregulation Metallomics - - QRT-PCR,Western blot TNF 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot TNF 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot TNF 29705531 Gastrointestinal-toxicity Gallus gallus Induce Copper synergy Upregulation Int Immunopharmacol - - QRT-PCR,Western blot TNF 29569195 Liver-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Environ Sci Pollut Res Int - - QRT-PCR,Western blot TNF 31896471 Immune-toxicity Gallus gallus Induce CuSO4 synergy Upregulation Ecotoxicol Environ Saf - - QRT-PCR, Western blot TNF 31713821 Immune-toxicity Gallus gallus Induce - - Upregulation Environ Sci Pollut Res Int - - QRT-PCR, Western blot TNF 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot TNF 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot TNF 29054015 Neuronal-toxicity Gallus gallus Induce CuSO4 synergy Upregulation J Inorg Biochem - - QRT-PCR, Western blot TNF 12560223 Leukemia Homo sapiens Inhibit Interferon-alpha synergy Downregulation Blood Lymphoma cell HuT 102 RT-PCR TNFR1 17673311 Leukemia Homo sapiens Inhibit TNF-alpha synergy Upregulation Biochim Biophys Acta Histiocytic lymphoma cell U-937 Western blot TNFRSF10D 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis Tnfrsf11a 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis Tnfrsf11b 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis TNFRSF11B 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis TNFRSF1A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Tnfrsf1b 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis Tnfrsf1b 12243866 Leukemia Mus musculus Inhibit - - Downregulation Toxicol Lett Myeloid leukemia cell JCS-16 Northern blot Tnfrsf21 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis TNFRSF21 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis Tnfrsf25 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis TNFRSF4 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis Tnfrsf8 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis TNFSF10 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TNFSF11 17530438 Brain-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis TNFSF18 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis TNFSF4 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis TNFSF5 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis TNFSF6 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis Tnfsf7 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Downregulation Pancreas Pancreas cell AR42J Microarray analysis TNFSF8 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis TNNI3 28094846 Heart-toxicity Homo sapiens Induce - - Downregulation British Journal ofPharmacology Cardiomyocyte Cardiomyocyte Microarray analysis TOLLIP 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR TOP1 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis TOP1 15178684 Leukemia Homo sapiens Inhibit - - Upregulation J Biol Chem Acute promyelocytic leukemia cell NB4 Western blot TOPOII 16884364 Ovary-cancer Homo sapiens Inhibit - - Downregulation Int J Gynecol Cancer Ovarian cancer cell MDAH 2774 Western blot TOPOII 21775093 Leukemia Homo sapiens Inhibit - - Upregulation Biomed Pharmacother Chronic myelogenous leukemia cell K-562 Western blot, IHC TOR1A 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis TORC1 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR TORC1 29762750 Reproductive-toxicity Gallus gallus Induce - - Downregulation Poult Sci - - QRT-PCR,Western blot TORC2 31945648 Immune-toxicity Gallus gallus Induce CuSO4 synergy Downregulation J Inorg Biochem - - QRT-PCR TP35 22801079 Neuronal-toxicity Rattus norvegicus Induce - - Upregulation Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi Neurons cell NEURONS QRT-PCR TP53 26225652 Breast-cancer Homo sapiens Inhibit Paclitaxel synergy Upregulation Asian Pac J Cancer Prev Breast cancer cell MCF7 QRT-PCR TP53BP1 26871293 Brain-cancer Homo sapiens Inhibit - - Upregulation Oncotarget Glioma cell U87 Western blot, IFA TP53INP1 19763917 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR TP53TG3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TP73 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TP73 28533173 Leukemia Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR TP73 22944098 Leukemia Homo sapiens Inhibit - - Upregulation Hematology Acute promyelocytic leukemia cell NB4 QRT-PCR TP73 19763917 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR TPD52 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TPD52L2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Tph 23518225 Neuronal-toxicity Mus musculus Induce - - Downregulation Neuroscience - - Western blot TPM4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TPP2 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis TPT1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TRA1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TRAD 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Traf1 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis TRAF1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Traf2 19730151 Pancreas-toxicity Rattus norvegicus Induce - - Upregulation Pancreas Pancreas cell AR42J Microarray analysis TRAIL 17530438 Brain-cancer Homo sapiens Inhibit - - Downregulation Mol Biol Rep Glioblastoma cell T98G Microarray analysis TRAIL 30127933 Liver-cancer Homo sapiens Inhibit Sorafenib synergy Upregulation Oncol Lett Liver cancer cell Huh7 Western blot TRAPPC4 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis TRAPPC6B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Trb3 23892647 Vascular-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR Trbeta1 28849461 Neuronal-toxicity Mus musculus Induce Taurine detoxicity Downregulation Adv Exp Med Biol - - QRT-PCR, Western blot TRERF1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TRF1 15904916 Gastric-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Gastric cancer cell MGC-803 RT-PCR, Western blot TRF2 17643074 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Acute lymphoblastic leukemia cell MOLT-4 QRT-PCR,Western blot TRF2 17643074 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Chronic myelogenous leukemia cell K-562 QRT-PCR,Western blot TRF2 17643074 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Acute promyelocytic leukemia cell NB4 QRT-PCR,Western blot TRF2 17643074 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Leukemia cell Jurkat QRT-PCR,Western blot TRF2 15904916 Gastric-cancer Homo sapiens Inhibit - - Upregulation Eur J Pharmacol Gastric cancer cell MGC-803 RT-PCR, Western blot TRIB2 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TRIB2 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis TRIM26 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TRIP12 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TRKA 29898774 Brain-cancer Homo sapiens Inhibit - - Upregulation Biol Res Neuroblastoma cell SKNSH RT-PCR TRKA 16569477 Brain-cancer Homo sapiens Inhibit - - Downregulation Cancer Lett Neuroblastoma cell IMR-32 Western blot TRKB 29898774 Brain-cancer Homo sapiens Inhibit - - Upregulation Biol Res Neuroblastoma cell SKNSH RT-PCR TRKB 16711005 Melanoma Homo sapiens Inhibit - - Downregulation J Huazhong Univ Sci Technolog Med Sci Bladder carcinoma cell ECV304 Western blot TRKB 16569477 Brain-cancer Homo sapiens Inhibit - - Upregulation Cancer Lett Neuroblastoma cell IMR-32 Western blot TRKC 29898774 Brain-cancer Homo sapiens Inhibit - - Upregulation Biol Res Neuroblastoma cell SKNSH RT-PCR TRPB3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TRPM4 31054354 Vascular-toxicity Homo sapiens Induce 9-phenanthrol detoxicity Upregulation Toxicol Lett Human umbilical vein endothelial cells HUVECs QRT-PCR,Western blot, IFA Trx 26775255 Pancreas-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Biochimie - - QRT-PCR Trx 27291853 Liver-toxicity Rattus norvegicus Induce Taurine detoxicity Downregulation Sci Rep - - Western blot TRX 31442540 Liver-toxicity Gallus gallus Induce - - Upregulation Toxicol In Vitro Primary hepatocyte Primary hepatocytes QRT-PCR,Western blot TRX 18661523 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Cancer Lung cancer cell NCI-H727 QRT-PCR,Western blot TRX 18661523 Lung-cancer Homo sapiens Inhibit - - Upregulation Int J Cancer Lung cancer cell NCI-H727 QRT-PCR,Western blot TRX 27291853 Liver-toxicity Homo sapiens Induce Taurine detoxicity Downregulation Sci Rep Hepatocellular carcinoma cell HEPG2 Western blot TRX1 18157160 Liver-cancer Homo sapiens Inhibit - - Upregulation Cell Res Hepatocellular carcinoma cell HEPG2 Western blot TRX1 25572414 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol lung cancer cell H841 Western blot TRX1 25197347 Leukemia Homo sapiens Inhibit PX-12 synergy Downregulation Int J Clin Exp Pathol Acute promyelocytic leukemia cell NB4 Western blot TRXR 18587442 Lung-cancer Homo sapiens Inhibit - - Upregulation Br J Pharmacol Lung adenocarcinoma cell A549 Western blot TSC1 29442453 Leukemia Homo sapiens Inhibit - - Upregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR Tsc2 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR TSC2 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR TSC2 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Upregulation Pharmazie Acute promyelocytic leukemia cell HL-60 Western blot TSC2 23469683 Leukemia Homo sapiens Inhibit Amp-activated-protein-kinase-(ampk)-activator-5-amino-4-imidazolecarboxamide-riboside synergy Downregulation Pharmazie Acute promyelocytic leukemia cell NB4 Western blot TSHZ3 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis Tsp1 29088724 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Oncotarget - - IHC TSP1 29088724 Rheumatoid-arthritis Homo sapiens Inhibit - - Downregulation Oncotarget Rheumatoid arthritis fbroblast-like synoviocyte RAFLS QRT-PCR, ELISA TSPAN3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TSPAN4 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TSPYL2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis TSPYL2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis TTC7B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TTCL2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TUBG1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TUBULIN 28829335 Liver-cancer Homo sapiens Inhibit - - Deacetylation Nanotechnology Hepatocellular carcinoma cell SMMC-7721 IFA, Western blot TUBULIN 29959200 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Mol Cancer Ther Acute myeloid leukemia cell MOLM13 Western blot TUBULIN 10029061 Leukemia Homo sapiens Inhibit - - Downregulation Cancer Res Chronic myelogenous leukemia cell K-562 Western blot Twist 24756364 Liver-cancer Rattus norvegicus Inhibit - - Downregulation J Cancer Res Clin Oncol Hepatoma cell MCA-RH7777 IHC, Western blot TXN 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis TXNDC9 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TXNIP 18231732 Myeloma Homo sapiens Inhibit - - Downregulation J Huazhong Univ Sci Technolog Med Sci Myeloma cell RPMI 8226 Microarray analysis TXNL2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis TYK2 24762999 Leukemia Homo sapiens Inhibit 5-aza-2'-deoxycytidine synergy Downregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 QRT-PCR TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H23 Kit TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung cancer cell NCI-H358 Kit TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H1650 Kit TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H1975 Kit TYMS 20530422 Colorectal-cancer Homo sapiens Inhibit - - Downregulation Anticancer Res Colorectal adenocarcinoma cell HT-29 QRT-PCR,Western blot TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H1650 QRT-PCR,Western blot TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung cancer cell NCI-H358 QRT-PCR, Western blot TYMS 31906234 Cervical-cancer Homo sapiens Inhibit ABT-737 synergy Downregulation Cancers (Basel) Cervix squamous cell carcinoma cell SiHa Western blot TYMS 28927142 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung cancer cell SK-MES-1 Western blot TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H23 Western blot TYMS 24691991 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol Lung adenocarcinoma cell NCI-H1975 Western blot TYR 11834893 Gastric-cancer Homo sapiens Inhibit - - Dephosphorylation Pharmacology Gastric cancer cell MGC-803 Flow cytometry TYROSINE 10448126 Vascular-toxicity Sus scrofa Induce - - Upregulation Toxicol Appl Pharmacol Porcine aortic endothelial cell PAEC Western blot UBE2B 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis UBE2H 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis UBE3A 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis UBE4B 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis UBP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis UCHl5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ucp2 24905690 Immune-toxicity Danio rerio Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR UGDH 25258189 Bone-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis UGT1A1 24928535 Ovary-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Ovarian cancer cell SK-OV-3 QRT-PCR UGT1A6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis UHRF1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Ulk1 32781346 Reproductive-toxicity Mus musculus Induce - - Upregulation Ecotoxicol Environ Saf - - QRT-PCR Ulk1 32044640 Reproductive-toxicity Mus musculus Induce - - Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 QRT-PCR Ulk1 31605998 Development-toxicity Mus musculus Induce NaF detoxicity Upregulation Chemosphere - - QRT-PCR Ulk1 31326754 Development-toxicity Mus musculus Induce - - Upregulation Chemosphere - - QRT-PCR ULK1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR ULK1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR ULK1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR ULK1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR UPA 15962302 Fibrosarcoma Homo sapiens Inhibit - - Downregulation J Cell Biochem Fibrosarcoma cell HT1080 Northern blot,luciferase, Western blot UPA 27039805 Brain-cancer Homo sapiens Inhibit - - Downregulation Asian Pac J Cancer Prev Glioblastoma cell U-87 MG QRT-PCR UPA 23851143 Breast-cancer Homo sapiens Inhibit Human-growth-hormone synergy Downregulation Mol Cell Endocrinol Breast cancer cell MCF7 QRT-PCR UPAR 15962302 Fibrosarcoma Homo sapiens Inhibit - - Downregulation J Cell Biochem Fibrosarcoma cell HT1080 Northern blot,luciferase, Western blot UPF2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis UQCRC1 19996132 Liver-cancer Homo sapiens Inhibit - - Downregulation Cancer Genomics Proteomics Liver adenocarcinoma cell SK-HEP-1 Proteome profiling UQCRH 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis UREB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis USF2 25436934 Leukemia Homo sapiens Inhibit - - Downregulation Toxicol Lett Acute promyelocytic leukemia cell HL-60 QRT-PCR, Western blot USP3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis UVRAG 29307831 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Osteosarcoma cell MG-63 QRT-PCR VAC 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J BurkittĄ¯s lymphoma cell MuTu Western blot VAMP1 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis VAMP4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis VANGL1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis VASP 20129490 Blood-toxicity Homo sapiens Induce - - Phosphorylation,Downregulation Transl Res Platelet cell Platelet Western blot VAV3 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Vcam1 22465848 Bone-toxicity Rattus norvegicus Induce - - Downregulation Bone Primary osteoblast progenitor cell Mature asteoblast QRT-PCR, RT-PCR VCIP135 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Vdac 27638049 Development-toxicity Mus musculus Induce - - Upregulation Arch Biochem Biophys Embryonic fibroblast ATF4 +/+MEF Western blot VDAC 17374990 Cervical-cancer Homo sapiens Inhibit - - Downregulation Cancer Biol Ther Cervical adenocarcinoma cell HeLa Western blot VDAC 17203211 Lymphoma Homo sapiens Inhibit - - Upregulation Int J Oncol Burkitt's lymphoma cell Ramos Western blot VDAC 14647451 Myeloma Homo sapiens Inhibit - - Upregulation Oncogene Multiple myeloma cell IM-9 Western blot VDAC 12939460 Immune-toxicity Homo sapiens Induce - - Downregulation Mol Cancer Ther Normal peripheral blood cell T cell Western blot VDAC2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis VDR 31205465 Rheumatoid-arthritis Homo sapiens Inhibit Vitamin-D synergy Upregulation PPAR Res Fibroblast-like synoviocyte fibroblast-like synoviocytes QRT-PCR,Western blot Vecad 27671604 Heart-toxicity Rattus norvegicus Induce - - Downregulation Sci Rep - - QRT-PCR,Western blot VECAD 27671604 Heart-toxicity Homo sapiens Induce - - Downregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR,Western blot Vegf 17007042 Gastric-cancer Mus musculus Inhibit - - Downregulation World J Gastroenterol - - IFA Vegf 29088724 Rheumatoid-arthritis Mus musculus Inhibit - - Downregulation Oncotarget - - IHC Vegf 23210436 Asthma Mus musculus Inhibit - - Upregulation Can J Physiol Pharmacol - - IHC Vegf 16273603 Liver-cancer Rattus norvegicus Inhibit - - Downregulation World J Gastroenterol - - IHC Vegf 15888669 Melanoma Mus musculus Inhibit - - Upregulation Toxicol Sci Melanoma cell B16-F10 IHC Vegf 22488045 Immune-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR Vegf 25413961 Lung-cancer Mus musculus Inhibit - - Downregulation Cell Biochem Biophys Lung cancer cell LEWIS QRT-PCR, Western blot Vegf 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Myeloid-derived suppressor cell Myeloid-derived suppressor cell RT-PCR Vegf 28454374 Skin-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Melanoma cell B16 RT-PCR Vegf 28454374 Liver-cancer Mus musculus Inhibit - - Downregulation Oncol Lett Hepatoma cell Heptoma 22 RT-PCR Vegf 16827809 Leukemia Mus musculus Inhibit - - Upregulation Cancer Sci - - Western blot Vegf 16827809 Liver-cancer Mus musculus Inhibit - - Upregulation Cancer Sci Liver cancer cell H22 Western blot VEGF 17997939 Leukemia Homo sapiens Inhibit - - Downregulation Zhong Xi Yi Jie He Xue Bao Chronic myelogenous leukemia cell K-562 ELISA VEGF 17650671 Leukemia Homo sapiens Inhibit - - Downregulation Zhonghua Xue Ye Xue Za Zhi Chronic myelogenous leukemia cell K-562 ELISA VEGF 30612216 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Toxicol Breast cancer cell MDA-MB-231 ELISA VEGF 30612216 Breast-cancer Homo sapiens Inhibit - - Downregulation Cell Biol Toxicol Breast cancer cell Hs 578T ELISA VEGF 15888669 Bladder-cancer Homo sapiens Inhibit - - Upregulation Toxicol Sci Microvascular endothelial cell HMEC-1 ELISA VEGF 15888669 Bladder-cancer Homo sapiens Inhibit - - Upregulation Toxicol Sci Bladder carcinoma cell J82 ELISA VEGF 22664115 Leukemia Homo sapiens Inhibit - - Downregulation Hematology Acute promyelocytic leukemia cell HL-60 ELISA, QRT-PCR VEGF 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis VEGF 25196641 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H QRT-PCR, ELISA VEGF 25196641 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97L QRT-PCR, ELISA VEGF 29088724 Rheumatoid-arthritis Homo sapiens Inhibit - - Downregulation Oncotarget Rheumatoid arthritis fbroblast-like synoviocyte RAFLS QRT-PCR, ELISA VEGF 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell KU7 QRT-PCR, Western blot VEGF 17007042 Gastric-cancer Homo sapiens Inhibit - - Downregulation World J Gastroenterol Gastric adenocarcinoma cell SGC-7901 QRT-PCR, Western blot VEGF 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell PC-3 QRT-PCR, Western blot VEGF 25283513 Prostate-cancer Homo sapiens Inhibit - - Downregulation Cancer Sci Prostate carcinoma cell LNCaP QRT-PCR, Western blot VEGF 31421153 Vascular-toxicity Homo sapiens Induce - - Downregulation Toxicol Lett Human umbilical vein endothelial cells HUVECs Western blot VEGF 20435036 Bladder-cancer Homo sapiens Inhibit - - Downregulation Exp Cell Res Bladder carcinoma cell 253JBV Western blot VEGF 26781180 Liver-cancer Homo sapiens Inhibit - - Downregulation Mol Med Rep Hepatocellular carcinoma cell MHCC97H Western blot VEGF 30554581 Laryngeal-cancer Homo sapiens Inhibit - - Downregulation Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Hela carcinoma cell HEP-2 Western blot VEGF 30477221 Gastric-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Gastric cancer cell MGC-803 Western blot VEGF 30477221 Gastric-cancer Homo sapiens Inhibit - - Downregulation Int J Mol Sci Gastric adenocarcinoma cell SGC-7901 Western blot VEGF 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell SMMC-7721 Western blot VEGF 23975599 Liver-cancer Homo sapiens Inhibit Icariin synergy Downregulation Cell Biochem Biophys Hepatocellular carcinoma cell HEPG2 Western blot VEGFA 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Lung adenocarcinoma cell A549 IFA, Western blot VEGFA 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Large cell lung cancer cell NCI-H460 IFA, Western blot VEGFA 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Small cell lung cancer cell NCI-H446 IFA, Western blot VEGFA 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFA 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFA 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFA 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFA 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Asian Pac J Cancer Prev Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFA 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Asian Pac J Cancer Prev Histiocytic lymphoma cell U-937 QRT-PCR VEGFA 29699374 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Asian Pac J Cancer Prev Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFA 29699374 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Asian Pac J Cancer Prev Histiocytic lymphoma cell U-937 QRT-PCR VEGFA 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell SK-OV-3 QRT-PCR,Western blot VEGFA 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell A2780 QRT-PCR,Western blot VEGFA 26274316 Vascular-toxicity Homo sapiens Induce - - Downregulation PLoS One Human umbilical vein endothelial cells HUVECs QRT-PCR,Western blot VEGFA 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung adenocarcinoma cell A549 Western blot VEGFA 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Small cell lung cancer cell NCI-H446 Western blot VEGFA 25728215 Cervical-cancer Homo sapiens Inhibit - - Upregulation Environ Toxicol Cervix squamous cell carcinoma cell SiHa Western blot VEGFB 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFB 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFB 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFB 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFB 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Asian Pac J Cancer Prev Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFB 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Asian Pac J Cancer Prev Histiocytic lymphoma cell U-937 QRT-PCR VEGFB 29699374 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Asian Pac J Cancer Prev Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFB 29699374 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Asian Pac J Cancer Prev Histiocytic lymphoma cell U-937 QRT-PCR VEGFC 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFC 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFC 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFC 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFC 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Asian Pac J Cancer Prev Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFD 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFD 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFR1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFR1 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFR1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFR1 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFR1 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Asian Pac J Cancer Prev Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFR1 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell SK-OV-3 Western blot VEGFR1 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell A2780 Western blot VEGFR2 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFR2 31863650 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFR2 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Upregulation Cell J Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFR2 31721534 Leukemia Homo sapiens Inhibit Thalidomide synergy Downregulation Cell J Histiocytic lymphoma cell U-937 QRT-PCR VEGFR2 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Upregulation Asian Pac J Cancer Prev Acute myelogenous leukemia cell KG-1 QRT-PCR VEGFR2 28670885 Leukemia Homo sapiens Inhibit Sorafenib synergy Downregulation Asian Pac J Cancer Prev Histiocytic lymphoma cell U-937 QRT-PCR VEGFR2 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell SK-OV-3 QRT-PCR,Western blot VEGFR2 30014256 Ovary-cancer Homo sapiens Inhibit - - Downregulation J Biol Inorg Chem Ovarian cancer cell A2780 QRT-PCR,Western blot VEGFR2 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Lung adenocarcinoma cell A549 RT-PCR VEGFR2 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Large cell lung cancer cell NCI-H460 RT-PCR VEGFR2 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Small cell lung cancer cell NCI-H446 RT-PCR VEGFR2 16159421 Leukemia Homo sapiens Inhibit - - Upregulation Ai Zheng Erythroleukemia cell TF-1 RT-PCR, Flow cytometry VEGFR2 16159421 Leukemia Homo sapiens Inhibit - - Upregulation Ai Zheng Erythroleukemia cell HEL RT-PCR, Flow cytometry VEGFR2 25088040 Lung-cancer Homo sapiens Inhibit - - Downregulation Curr Cancer Drug Targets Human umbilical vein endothelial cells HUVECs RT-PCR, Western blot VEGFR2 28928847 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Human umbilical vein endothelial cells HUVECs Western blot VEGFR3 16159421 Leukemia Homo sapiens Inhibit - - Upregulation Ai Zheng Erythroleukemia cell HEL RT-PCR, Flow cytometry VEGFR3 16159421 Leukemia Homo sapiens Inhibit - - Upregulation Ai Zheng Acute promyelocytic leukemia cell NB4 RT-PCR, Flow cytometry VEGFR3 16159421 Leukemia Homo sapiens Inhibit - - Upregulation Ai Zheng Myeloma cell RPMI 8226 RT-PCR, Flow cytometry VGLL4 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Vim 24756364 Liver-cancer Rattus norvegicus Inhibit - - Downregulation J Cancer Res Clin Oncol Hepatoma cell MCA-RH7777 Western blot VIM 25258189 Bone-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Bone marrow-derived mesenchymal stem cell HMSC-bm Proteomics analysis VIM 27671604 Heart-toxicity Homo sapiens Induce - - Upregulation Sci Rep Aortic endothelial cell HAECs QRT-PCR VIM 31003765 Liver-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell HCCLM3 QRT-PCR,Western blot VIM 31003765 Liver-cancer Homo sapiens Inhibit - - Downregulation Biochem Biophys Res Commun Hepatocellular carcinoma cell SMMC-7721 QRT-PCR,Western blot VIM 24729530 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Carcinog Breast cancer cell MDA-MB-231 QRT-PCR, Western blot, IHC VIM 28956730 Lung-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Normal lung epithelial cell BEAS-2B Western blot VIM 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell 5-8F Western blot VIM 30770775 Nasopharyngeal-cancer Homo sapiens Inhibit - - Downregulation J Exp Clin Cancer Res Nasopharyngeal carcinoma cell CNE-2 Western blot VIM 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Nasopharyngealcarcinoma cell 5-8F Western blot VIM 30472098 Nasopharyngeal-cancer Homo sapiens Inhibit - - Upregulation Exp Cell Res Nasopharyngeal carcinoma cell CNE-2 Western blot VIM 25010681 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Colorectal adenocarcinoma cell HT-29 Western blot VIM 24729530 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Carcinog Breast cancer cell BT-549 Western blot VIM 24680928 Liver-cancer Homo sapiens Inhibit - - Downregulation Toxicol Lett Hepatocellular carcinoma cell MHCC97H Western blot VLDLR 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Vps34 32044640 Reproductive-toxicity Mus musculus Induce - - Upregulation J Hazard Mater Testis leydig tumor cell MLTC-1 QRT-PCR Vps54 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR VWF 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WASl 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR WBP5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WBSCR27 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WDFY2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WDR19 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WDR41 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WDR45 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Wee 23337567 Bone-cancer Rattus norvegicus Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR106 Western blot WEE 29048129 Myeloma Homo sapiens Inhibit - - Upregulation Br J Haematol Myeloma cell MM.1S Western blot WEE 22730174 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation,Upregulation J Cell Biochem Hepatocellular carcinoma cell HEPG2 Western blot WEE 22730174 Liver-cancer Homo sapiens Inhibit - - Dephosphorylation,Upregulation J Cell Biochem Hepatocellular carcinoma cell SMMC-7721 Western blot WEE 10850458 Myeloma Homo sapiens Inhibit - - Downregulation Cancer Res Myeloma cell MC/CAR Western blot WEE 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell MG-63 Western blot WEE 23337567 Bone-cancer Homo sapiens Inhibit - - Upregulation Biochem Pharmacol Osteosarcoma cell UMR-106 Western blot WEE1HU 18088464 Leukemia Homo sapiens Inhibit - - Upregulation Zhongguo Shi Yan Xue Ye Xue Za Zhi Acute promyelocytic leukemia cell NB4 RT-PCR WHSC1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WIP1 21175813 Liver-cancer Homo sapiens Inhibit - - Downregulation J Gastroenterol Hepatol Hepatocellular carcinoma cell HEPG2 Western blot WIPF1 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell MDA-MB-231 QRT-PCR WIPF1 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell SUM-159 QRT-PCR WIPF1 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell MCF7 QRT-PCR WIPI2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR WIPI2 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR WISP1 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis WNK2 19763917 Leukemia Homo sapiens Inhibit - - Upregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR WNT1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Huh7 QRT-PCR, Western blot WNT1 24678763 Liver-cancer Homo sapiens Inhibit - - Downregulation J Hematol Oncol Hepatocellular carcinoma cell Hep3B QRT-PCR, Western blot WNT16 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis WNT7A 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis WT1 16966277 Leukemia Homo sapiens Inhibit - - Downregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 RT-PCR, Western blot WWOX 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis Xbp1 23954561 Immune-toxicity Mus musculus Induce 4-phenylbutyric-acid detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR Xbp1 23954561 Immune-toxicity Mus musculus Induce N-acetylcysteine detoxicity Upregulation Toxicol Appl Pharmacol Leukemia cell RAW 264.7 RT-PCR XBP1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 Microarray analysis XBP1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 Microarray analysis XBP1 23883479 Leukemia Homo sapiens Inhibit AMN107 synergy Upregulation Exp Biol Med (Maywood) Chronic myelogenous leukemia cell K-562 QRT-PCR XBP1 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot XBP1 22959511 Leukemia Homo sapiens Inhibit - - Upregulation Leuk Res Chronic myelogenous leukemia cell K-562 QRT-PCR, Western blot XBP1 22922937 Myeloma Homo sapiens Inhibit Sulforaphane synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 RT-PCR XBP1 22922937 Myeloma Homo sapiens Inhibit Sulforaphane synergy Upregulation Oncol Rep Myeloma cell ARP-1 RT-PCR XBP1 22922937 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 RT-PCR XBP1 22922937 Myeloma Homo sapiens Inhibit Bortezomib synergy Upregulation Oncol Rep Myeloma cell ARP-1 RT-PCR XBP1 22922937 Myeloma Homo sapiens Inhibit Erysolin synergy Upregulation Oncol Rep Multiple myeloma cell KMS-11 RT-PCR XBP1 22922937 Myeloma Homo sapiens Inhibit Erysolin synergy Upregulation Oncol Rep Myeloma cell ARP-1 RT-PCR XBP1S 19878647 Leukemia Homo sapiens Inhibit - - Upregulation Biochem Biophys Res Commun Polymorphonuclear neutrophils cell Polymorphonuclear neutrophils RT-PCR Xbpis 23892647 Vascular-toxicity Mus musculus Induce - - Downregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR Xbpiu 23892647 Vascular-toxicity Mus musculus Induce - - Upregulation Arch Toxicol Lymphatic endothelial cell SVEC4-10 QRT-PCR Xiap 26815588 Heart-toxicity Rattus norvegicus Induce Morphine detoxicity Downregulation Biol Trace Elem Res Heart myoblast H9C2 QRT-PCR XIAP 19763917 Leukemia Homo sapiens Inhibit - - Downregulation Med Oncol Acute promyelocytic leukemia cell NB4 QRT-PCR XIAP 30316766 Leukemia Homo sapiens Inhibit BKM120 synergy Downregulation Eur J Pharmacol Acute promyelocytic leukemia cell NB4 QRT-PCR XIAP 28927142 Lung-cancer Homo sapiens Inhibit - - Downregulation Oncol Lett Lung cancer cell SW 900 Western blot XIAP 28187727 Liver-cancer Homo sapiens Inhibit Cryptotanshinone synergy Upregulation BMC Complement Altern Med Liver cancer cell BEL-7404 Western blot XIAP 23178716 Ovary-cancer Homo sapiens Inhibit - - Downregulation FEBS Lett Ovarian carcinoma cell HEY Western blot XIAP 21947421 Liver-cancer Homo sapiens Inhibit Oridonin synergy Downregulation Int J Oncol Liver cancer cell BEL-7402 Western blot XIAP 20605902 Leukemia Homo sapiens Inhibit Curcumin synergy Upregulation J Pharmacol Exp Ther Histiocytic lymphoma cell U-937 Western blot XIAP 18546268 Leukemia Homo sapiens Inhibit Genistein synergy Downregulation Int J Cancer Histiocytic lymphoma cell U-937 Western blot XIAP 18359480 Leukemia Homo sapiens Inhibit Quercetin synergy Downregulation Biochem Pharmacol Histiocytic lymphoma cell U-937 Western blot XIAP 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Lett Chronic myelogenous leukemia cell K-562 Western blot XIAP 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Lett Chronic myelogenous leukemia cell KU812 Western blot XIAP 29944906 Leukemia Homo sapiens Inhibit Cisplatin synergy Downregulation Cancer Lett Chronic myeloid leukemia cell MEG-A2 Western blot XIAP 16174796 Leukemia Homo sapiens Inhibit - - Downregulation J Pharmacol Exp Ther Blood monocyte BLOOD MONOCYTES Western blot XIAP 16174796 Leukemia Homo sapiens Inhibit - - Downregulation J Pharmacol Exp Ther Histiocytic lymphoma cell U-937 Western blot XIAP 16105982 Leukemia Homo sapiens Inhibit - - Downregulation Blood Acute myeloid leukemia cell ML1 Western blot XIAP 12168106 Leukemia Homo sapiens Inhibit - - Downregulation Int J Oncol Histiocytic lymphoma cell U-937 Western blot XIAP 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Upregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot XIAP 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Acute promyelocytic leukemia cell HL-60 Western blot XIAP 11368438 Leukemia Homo sapiens Inhibit STI-571 synergy Downregulation Leukemia Chronic myelogenous leukemia cell K-562 Western blot XIAP 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Downregulation Leuk Lymphoma Acute myelogenous leukemia cell KG-1a Western blot XIAP 25739941 Leukemia Homo sapiens Inhibit Aclacinomycin-a synergy Upregulation Leuk Lymphoma Acute promyelocytic leukemia cell HL-60 Western blot XIAP 25572414 Lung-cancer Homo sapiens Inhibit - - Downregulation Int J Oncol lung cancer cell H841 Western blot XPA 28237621 Lung-toxicity Homo sapiens Induce - - Downregulation DNA Repair (Amst) Lung fibroblast cell IMR-90 QRT-PCR Xpc 28237621 Skin-cancer Mus musculus Induce - - Downregulation DNA Repair (Amst) Primary keratinocyte Primary mouse keratinocyte Western blot XPC 28237621 Skin-cancer Homo sapiens Induce - - Downregulation DNA Repair (Amst) Lung fibroblast cell IMR-90 QRT-PCR, Western blot XPNPEP1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis XRCC3 17530438 Brain-cancer Homo sapiens Inhibit - - Upregulation Mol Biol Rep Glioblastoma cell U-87 MG Microarray analysis Yap 32954055 Vascular-toxicity Rattus norvegicus Induce Y27632 detoxicity Phosphorylation Bioact Mater smooth muscle cell A7r5 Western blot Yap 32954055 Vascular-toxicity Rattus norvegicus Induce verteporfin detoxicity Phosphorylation Bioact Mater smooth muscle cell A7r5 Western blot YAP 32954055 Vascular-toxicity Homo sapiens Induce - - Downregulation Bioact Mater Aortic SMC cell VSMCs Western blot YLpM1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis YT521 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis YWHAH 29442453 Leukemia Homo sapiens Inhibit - - Downregulation Adv Clin Exp Med Acute promyelocytic leukemia cell HL-60 QRT-PCR YY1 21792014 Cervical-cancer Homo sapiens Inhibit - - Downregulation Int J Gynecol Cancer Cervical adenocarcinoma cell HeLa RT-PCR, Western blot ZBTB42 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ZC3H11A 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ZDHHC2 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZDHHC6 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZEB1 28956730 Lung-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Normal lung epithelial cell BEAS-2B Western blot ZEB1 25010681 Colorectal-cancer Homo sapiens Inhibit - - Upregulation Cancer Biol Ther Colorectal adenocarcinoma cell HT-29 Western blot ZEB1 24729530 Breast-cancer Homo sapiens Inhibit - - Downregulation Mol Carcinog Breast cancer cell MDA-MB-231 Western blot ZEB2 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell MDA-MB-231 QRT-PCR ZEB2 28239645 Breast-cancer Homo sapiens Inhibit - - Downregulation JCI Insight Breast cancer cell SUM-159 QRT-PCR Zfand5 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ZFAND5 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZFYVE1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell BxPC-3 QRT-PCR ZFYVE1 31420604 Pancreas-cancer Homo sapiens Inhibit - - Upregulation Oncogene Pancreatic cancer cell MIA PaCa-2 QRT-PCR ZMPSTE24 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZMPSTE24 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ZNF11B 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF198 17121903 Leukemia Homo sapiens Inhibit - - Downregulation Clin Cancer Res Embryonic kidney cell HEK-293 Western blot ZNF200 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ZNF230 20016248 Skin-toxicity Homo sapiens Induce - - Downregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ZNF283 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF333 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF36 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF37 20016248 Skin-toxicity Homo sapiens Induce - - Upregulation Skin Pharmacol Physiol Keratinocyte HACAT Microarray analysis ZNF429 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF516 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF525 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF552 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ZNF554 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF600 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF70 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZNF720 25258189 Vascular-toxicity Homo sapiens Induce - - Downregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ZNF778 25258189 Vascular-toxicity Homo sapiens Induce - - Upregulation Environ Toxicol Umbilical mesenchymal stem cell HUMSC Microarray analysis ZNF9 20458559 Breast-cancer Homo sapiens Inhibit - - Downregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZO1 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - QRT-PCR,Western blot ZO2 31585240 Gastrointestinal-toxicity Cyprinus carpio Induce Zinc detoxicity Downregulation Fish Shellfish Immunol - - QRT-PCR Zpbp1 32460071 Reproductive-toxicity Mus musculus Induce - - Downregulation Sci Total Environ - - QRT-PCR ZRANB1 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis ZTA 21605886 Lung-cancer Homo sapiens Inhibit - - Upregulation Virology Lung adenocarcinoma cell A549 QRT-PCR ZTA 21605886 Lung-cancer Homo sapiens Inhibit - - Upregulation Virology Nasopharyngeal carcinoma cell CNE1 QRT-PCR ZTA 21605886 Lung-cancer Homo sapiens Inhibit - - Upregulation Virology Nasopharyngeal carcinoma cell NPC QRT-PCR ZTA 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J BurkittĄ¯s lymphoma cell MuTu QRT-PCR, Western blot ZTA 28637474 Lymphoma Homo sapiens Inhibit - - Downregulation Virol J BurkittĄ¯s lymphoma cell RaeL Western blot ZW10 20458559 Breast-cancer Homo sapiens Inhibit - - Upregulation Med Oncol Breast cancer cell MCF7 Microarray analysis