A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name APOE
Type gene
Species Mus musculus
Tissue nerve
Experiment Method PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description The APOE E4 allele, depression and neuroticism have each been found to have adverse associations with contemporaneously measured cognitive ability and subsequent cognitive decline. Possession of the E4 allele of the APOE gene has been linked to higher ris
Regulation Gene NA
Year 2018
Pubmed ID 29451880
Title Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA