Details
| Name | TP53 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | brain |
| Experiment Method | Western blot, qRT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | DS-3032b treatment enhanced TP53 target gene expression and induced G1 cell cycle arrest, senescence and apoptosis. |
| Regulation Gene | NA |
| Year | 2017 |
| Pubmed ID | 29416773 |
| Title | Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma. |
| Drug | DS-3032b |
| Disease | neuroblastoma |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |