Details
| Name | TP53 |
| Type | gene |
| Species | Mus musculus |
| Tissue | MEF |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Cdc42GAP-/- mouse embryonic fibroblasts and/or tissues display reduced population doubling, significantly dampened DNA damage repair activity after DNA-damaging agent treatment, accumulated genomic abnormalities, and induction of p53, p16Ink4a, p21Cip1, a |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17227869 |
| Title | Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |