Details
| Name | TP53 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | osteogenic sarcomas,Lymphoma |
| Experiment Method | Western Blots,RT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | MYC inactivation was associated with prototypical markers of senescence, including acidic beta-gal staining, induction of p16INK4a, and p15INK4b expression. Moreover, MYC inactivation induced global changes in chromatin structure associated with the marke |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17664422 |
| Title | Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |