A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TP53
Type gene
Species Mus musculus
Tissue MEFs
Experiment Method PCR,RT-PCR,Immunoblotting,other
Up/Down NA
Pro/Anti Pro
Funtion Description Ectopic expression of conditional murine p53 (p53val135) and oncogenic ras is enough to induce a senescent-like growth arrest at the restrictive temperature.
Regulation Gene NA
Year 2008
Pubmed ID 18204081
Title PPP1CA contributes to the senescence program induced by oncogenic Ras.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA