A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TP53
Type gene
Species Mus musculus
Tissue MEFs
Experiment Method qRT-PCR,Northern Blot,Western Blots,other
Up/Down NA
Pro/Anti Pro
Funtion Description p53 activity seems to act as a necessary but not sufficient condition for senescence to arise. Maintaining cells in the arrested state for long periods does not switch reversible arrest to cellular senescence.
Regulation Gene NA
Year 2008
Pubmed ID 18800172
Title Characterization of the p53 response to oncogene-induced senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA