| Name |
TP53
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
dermal fibroblasts
|
| Experiment Method |
PCR,Immunofluorescence,Western Analysis
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
Hutchinson-Gilford progeria syndrome (HGPS) is a rare, debilitating disease with early mortality and rapid onset of aging-associated pathologies. It is linked to mutations in LMNA, which encodes A-type nuclear lamins. The most frequent HGPS-associated LMN
|
| Regulation Gene |
NA
|
| Year |
2008
|
| Pubmed ID |
18843043
|
| Title |
Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p55.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|