A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name APOE
Type gene
Species Mus musculus
Tissue aorta;heart
Experiment Method western blotting and PCR assays;Senescence-associated b-Gal staining;ELISA and biochemical analyses
Up/Down NA
Pro/Anti Anti
Funtion Description Exenatide mitigated diet-induced vascular aging and atherosclerotic plaque growth in ApoE-deficient mice under chronic stress.These results indicate that the exenatide-mediated beneficial vascular actions are likely attributable, at least in part, to the
Regulation Gene NA
Year 2017
Pubmed ID 28734203
Title Exenatide mitigated diet-induced vascular aging and atherosclerotic plaque growth in ApoE-deficient mice under chronic stress.
Drug exenatide
Disease atherosclerotic
Environment Factors diet
Circulating NA
Variant NA
High-throughput NA