A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TP53
Type gene
Species Worm
Tissue NA
Experiment Method qRT-PCR,Western Blot,other
Up/Down NA
Pro/Anti Pro
Funtion Description Considerable evidence supports a dual role for p53 in eliciting different responses depending on level of cellular stress. Mild or transient cellular damage, such as mild increase in free radical production, minor DNA damage, and transitory glucose or ATP
Regulation Gene NA
Year 2009
Pubmed ID 19416129
Title p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA