| Name |
TP53
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
HEK-293T,U2OS,p54-deficient cells
|
| Experiment Method |
qPCR,Immunoblot,cell infection,Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Researchers have analysed miRNA levels in Zmpste24-deficient mice, a model of Hutchinson-Gilford progeria syndrome. We have found that expression of the miR-29 family of miRNAs is markedly upregulated in Zmpste24(-/-) progeroid mice as well as during norm
|
| Regulation Gene |
miR-29
|
| Year |
2011
|
| Pubmed ID |
21522133
|
| Title |
Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p54.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|