Details
| Name | TP63 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | fibroblasts |
| Experiment Method | qRT-PCR, microarray |
| Up/Down | differential expression |
| Pro/Anti | NA |
| Funtion Description | we tracked the progression of RT abnormalities during development, revealing altered RT of the TP63 gene as an early event in disease progression of both HGPS and RTS. Moreover, the RT abnormalities in progeroid patients were associated with altered isofo |
| Regulation Gene | NA |
| Year | 2017 |
| Pubmed ID | 29196523 |
| Title | DNA replication timing alterations identify common markers between distinct progeroid diseases |
| Drug | 0 |
| Disease | Hutchinson-Gilford progeria syndrome, Rothmund-Thomson syndrome (RTS) |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | GSE98475 |