A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TRF2
Type gene
Species Homo sapiens
Tissue NA
Experiment Method Western blotting
Up/Down NA
Pro/Anti Pro
Funtion Description Cells lacking WRN demonstrate genomic instability, including telomeric abnormalities and undergo premature senescence, suggesting defects in telomere metabolism,this notion is strongly supported by our finding of physical and functional interactions betwe
Regulation Gene NA
Year 2004
Pubmed ID 14712220
Title TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA