A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TRIM28
Type gene
Species Homo sapiens
Tissue NA
Experiment Method PCR
Up/Down Up
Pro/Anti Pro
Funtion Description Here we describe a role for TRIM28 (also known as KRAB-associated protein 1, KAP1) on mediating oncogene-induced senescence (OIS). TRIM28 accumulates during OIS becoming phosphorylated on serine 824.
Regulation Gene NA
Year 2014
Pubmed ID 25160591
Title TRIM28/KAP1 regulates senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA