A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name APOE
Type gene
Species Homo sapiens
Tissue NA
Experiment Method PCR,other
Up/Down NA
Pro/Anti Anti
Funtion Description Recent evidence indicates that the absence of 4 allele seems to be a favorable survival factor. If this is the case, the frequency of 4 allele in healthy aged individuals would be expected to be lower compared to its distribution in the general population
Regulation Gene NA
Year 2006
Pubmed ID 17234815
Title Lower prevalence of epsilon 4 allele of apolipoprotein E gene in healthy, longer-lived individuals of Hellenic origin.
Drug NA
Disease CHD
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA