Details
| Name | TXNIP |
| Type | gene |
| Species | Mus musculus |
| Tissue | kidney |
| Experiment Method | PCR, RNAi, Western blot |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | However, in normal mice, TXNIP deficiency induced metabolic aging of mice and cellular senescence of kidney cells by inducing AKT activity and aging-associated gene expression. Altogether, these results suggest that TXNIP regulates cellular senescence by |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 30244523 |
| Title | TXNIP regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress. |
| Drug | 0 |
| Disease | NA |
| Environment Factors | H2O2 |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |