A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name UBC
Type gene
Species Homo sapiens
Tissue bone
Experiment Method PCR,other
Up/Down Down
Pro/Anti Pro
Funtion Description The UBC gene expression gradually decreased during passaging along with the reduction in series of molecules including hub genes; CDK1, CCNA2, MCM10, E2F1, BRCA1, HIST1H1A and HIST1H3B. UBC knockdown in hBM-MSCs induced impaired proliferation in dose-depe
Regulation Gene NA
Year 2018
Pubmed ID 29382826
Title Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA