Details
| Name | UBE2E3 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | retinal pigment epithelial |
| Experiment Method | qPCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Cells depleted of UBE2E3 become senescent in the absence of overt DNA damage and have a distinct senescence-associated secretory phenotype, increased mitochondrial and lysosomal mass, an increased sensitivity to mitochondrial and lysosomal poisons, and an |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29879550 |
| Title | Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |