A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name UCP1
Type gene
Species Homo sapiens
Tissue NA
Experiment Method PCR,Transfection
Up/Down NA
Pro/Anti NA
Funtion Description In humans, the variability of the UCP1 gene is associated with obesity, fat gain and metabolism. Since regulation of metabolism is one of the key-pathways in lifespan extension, we tested the possible effects of UCP1 variability on survival. Two polymorph
Regulation Gene NA
Year 2011
Pubmed ID 21827845
Title Two variants located in the upstream enhancer region of human UCP1 gene affect gene expression and are correlated with human longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA