| Name |
WNT16B
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
fibroblasts
|
| Experiment Method |
PCR, RNAi, Western blot, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
We found that WNT16B is overexpressed in cells undergoing stress-induced premature senescence and oncogene-induced senescence in both MRC5 cell line and the in vivo murine model of K-Ras(V12)-induced senescence.
|
| Regulation Gene |
NA
|
| Year |
2009
|
| Pubmed ID |
19951988
|
| Title |
WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway.
|
| Drug |
LY294002
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|