Details
| Name | WRN |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | Knockdown,other |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | The physiologic critical telomere shortening after serial rounds of cell division or acute DNA damage, known to inhibit the binding of telomerebinding proteins TRF1 and TRF2 and increasing telomere erosion, may promote telomere loop disruption and WRNmedi |
| Regulation Gene | NA |
| Year | 2006 |
| Pubmed ID | 17014852 |
| Title | Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |