A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name WRN
Type gene
Species Homo sapiens
Tissue MCF7,GM08402,AG03141D,HG2940
Experiment Method Western blot,knockdown
Up/Down NA
Pro/Anti Anti
Funtion Description The gene responsible for Werner syndrome codes for a RecQ-type DNA helicase and is believed to be involved in different aspects of DNA repair, replication, and transcription. The human Werner protein (WRN) translocates from nucleoli to the nucleoplasm upo
Regulation Gene NA
Year 2007
Pubmed ID 17521388
Title Werner syndrome protein prevents DNA breaks upon chromatin structure alteration.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA