| Name |
WRN
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
Blood
|
| Experiment Method |
RT-PCR,Microarray,Western blot,other
|
| Up/Down |
Down
|
| Pro/Anti |
Anti
|
| Funtion Description |
Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-like DNA helicase. Mice lacking the helicase domain of the WRN homologue exhibit many phenotypic features of WS, including a prooxidant status and a shorter mean life span co
|
| Regulation Gene |
NA
|
| Year |
2010
|
| Pubmed ID |
19741171
|
| Title |
Vitamin C restores healthy aging in a mouse model for Werner syndrome.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|