A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name WRN-1
Type gene
Species Caenorhabditis elegans
Tissue NA
Experiment Method RT-PCR
Up/Down Down
Pro/Anti Anti
Funtion Description When wrn-1 expression was inhibited by RNA interference (RNAi), a slight reduction in C. elegans life span was observed, with accompanying signs of premature aging.
Regulation Gene NA
Year 2004
Pubmed ID 15115755
Title A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA