Details
| Name | XAF1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | lung |
| Experiment Method | RT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We found that XAF1 expression was increased by genotoxic agents, such as doxorubicin and ionizing radiation in pulmonary microvascular endothelial cells, consequently leading to premature senescence. |
| Regulation Gene | NA |
| Year | 2016 |
| Pubmed ID | 26802028 |
| Title | XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence. |
| Drug | NA |
| Disease | lung cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |