A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ATP7a
Type gene silence
Species Mus musculus
Tissue NA
Experiment Method PCR
Up/Down Up
Pro/Anti Pro
Funtion Description For both genes, older animal cohorts showed reproducible increases in transcripts expressed from the silenced alleles. The results support the hypothesis that epigenetic loss of gene repression occurs in normal tissues and may be a contributing factor in
Regulation Gene Atp7a
Year 2003
Pubmed ID 14704185
Title Age-associated activation of epigenetically repressed genes in the mouse.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA