A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CISD2
Type gene silence
Species Mus musculus
Tissue NA
Experiment Method Western blot
Up/Down NA
Pro/Anti NA
Funtion Description Our study also reveals that Cisd2 is primarily localized in the mitochondria and that mitochondrial degeneration appears to have a direct phenotypic consequence that triggers the accelerated aging process in Cisd2 knockout mice; furthermore, mitochondrial
Regulation Gene CISD2
Year 2009
Pubmed ID 19451219
Title Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA