| Name |
DAXX
|
| Type |
gene silence
|
| Species |
Mus musculus
|
| Tissue |
Mouse ovarian surface epithelium
|
| Experiment Method |
RNAi,Western Blotting,qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
In this study, we both over-expressed DAXX and depleted DAXX in primary mOSE cells. We found that Daxx deletion accelerated senescence in a p53/p21-dependent manner and promoted DNA damage by interacting with PML bodies without affecting cell cycle progre
|
| Regulation Gene |
NA
|
| Year |
2013
|
| Pubmed ID |
23542781
|
| Title |
DAXX silencing suppresses mouse ovarian surface epithelial cell growth by inducing senescence and DNA damage
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|