Details
| Name | LBR |
| Type | gene silence |
| Species | Mus musculus |
| Tissue | B and T lymphocytes |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | We describe a mouse pedigree, Lym3, with normal bone marrow and thymic development but profound and progressive lymphopenia particularly within the T cell compartment. Reduced T cell homeostatic proliferative potential and life span in vivo were found to |
| Regulation Gene | NA |
| Year | 2012 |
| Pubmed ID | 22105998 |
| Title | Reduced lymphocyte longevity and homeostatic proliferation in lamin B receptor-deficient mice results in profound and progressive lymphopenia |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |